DT-13, a saponin of dwarf lilyturf tuber, exhibits anti-cancer activity by down-regulating C-C chemokine receptor type 5 and vascular endothelial growth factor in MDA-MB-435 cells

Chinese Journal of Natural Medicines

Volumn 12, Issue 1, 2014, Pages 24-29

  Ren Ping, Zhao ^a   Sen Sen, Lin ^a   Yuan, Sheng Tao ^a   Yu, Bo Yang ^a   Bai, Xian Shu ^b   Sun, Li ^a   Zhang, Lu Yong ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

^b SAARLAND UNIVERSITY   (Germany)

Author keywords

Anticancer activity; CCR5; DT 13; HIF 1 ; Ophiopogon japonicus; Saponin; VEGF

Indexed keywords

ANTINEOPLASTIC AGENT; CHEMOKINE RECEPTOR CCR5; DT 13; HYPOXIA INDUCIBLE FACTOR 1ALPHA; MESSENGER RNA; SAPONIN DERIVATIVE; UNCLASSIFIED DRUG; VASCULOTROPIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER INHIBITION; CELL ADHESION; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; DRUG SCREENING; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LUNG METASTASIS; METASTASIS INHIBITION; MIGRATION INHIBITION; MOUSE; NONHUMAN; PROTEIN CONTENT; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ANTICANCER ACTIVITY; CCR5; DT-13; HIF-1Α; OPHIOPOGON JAPONICUS; R285; SAPONIN; VEGF;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; BREAST NEOPLASMS; CELL ADHESION; CELL LINE, TUMOR; CELL MOVEMENT; DRUGS, CHINESE HERBAL; FEMALE; HUMANS; LIRIOPE PLANT; MICE; MICE, NUDE; PLANT TUBERS; RECEPTORS, CCR5; SAPONINS; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84893408222     PISSN: 20956975     EISSN: 18755364     Source Type: Journal    
DOI: 10.1016/S1875-5364(14)60005-4     Document Type: Article

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