The saponin monomer of dwarf lilyturf tuber, DT-13, inhibits angiogenesis under hypoxia and normoxia via multi-targeting activity

Oncology Reports

Volumn 29, Issue 4, 2013, Pages 1379-1386

  Zhao, Renping ^a   Sun, Li ^a   Lin, Sensen ^a   Bai, Xianshu ^b   Yu, Boyang ^a   Yuan, Shengtao ^a   Zhang, Luyong ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

^b SAARLAND UNIVERSITY   (Germany)

Author keywords

Angiogenesis; DT 13; Dwarf lilyturf tuber; Human umbilical vein endothelial cells; Hypoxia; Normoxia; Vascular endothelial growth factor

Indexed keywords

DT 13; HYPOXIA INDUCIBLE FACTOR 1ALPHA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN KINASE B; SAPONIN DERIVATIVE; UNCLASSIFIED DRUG; VASCULOTROPIN; VASCULOTROPIN RECEPTOR 2;

ANTIANGIOGENIC ACTIVITY; ARTICLE; CELL HYPOXIA; CELL PROLIFERATION; CHORIOALLANTOIS; CONTROLLED STUDY; DOWN REGULATION; DRUG STRUCTURE; DWARF LILYTURF TUBER; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; MIGRATION INHIBITION; PRIORITY JOURNAL; TUBER (GENUS); UMBILICAL VEIN ENDOTHELIAL CELL; WESTERN BLOTTING;

ANIMALS; BREAST NEOPLASMS; CELL ADHESION; CELL HYPOXIA; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; CHICKENS; CHORIOALLANTOIC MEMBRANE; FEMALE; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; LIRIOPE PLANT; NEOVASCULARIZATION, PATHOLOGIC; SAPONINS; SIGNAL TRANSDUCTION; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84874755348     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2013.2272     Document Type: Article

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