-
2
-
-
49749142616
-
Esophageal and gastric cardia cancers on 4238 Chinese patients residing in municipal and rural regions: A histopathological comparison during 24-year period
-
Fan YJ, Song X, Li JL, Li XM, Liu B, et al. (2008) Esophageal and gastric cardia cancers on 4238 Chinese patients residing in municipal and rural regions: a histopathological comparison during 24-year period. World J Surg 32: 1980-1988.
-
(2008)
World J Surg
, vol.32
, pp. 1980-1988
-
-
Fan, Y.J.1
Song, X.2
Li, J.L.3
Li, X.M.4
Liu, B.5
-
3
-
-
54349128438
-
Multidisciplinary management of gastric and gastroesophageal cancers
-
Moehler M, Lyros O, Gockel I, Galle PR, Lang H (2008) Multidisciplinary management of gastric and gastroesophageal cancers. World J Gastroenterol 14: 3773-3780.
-
(2008)
World J Gastroenterol
, vol.14
, pp. 3773-3780
-
-
Moehler, M.1
Lyros, O.2
Gockel, I.3
Galle, P.R.4
Lang, H.5
-
4
-
-
33749369305
-
Adenocarcinoma of the Esophagogastric Junction: Surgical Therapy Based on 1602 Consecutive Resected Patients
-
DOI 10.1016/j.soc.2006.07.015, PII S1055320706000603, Adenocarcinoma of the Gastroesophageal Junction
-
Feith M, Stein HJ, Siewert JR (2006) Adenocarcinoma of the esophagogastric junction: surgical therapy based on 1602 consecutive resected patients. Surg Oncol Clin N Am 15: 751-764. (Pubitemid 44499032)
-
(2006)
Surgical Oncology Clinics of North America
, vol.15
, Issue.4
, pp. 751-764
-
-
Feith, M.1
Stein, H.J.2
Siewert, J.R.3
-
6
-
-
77950524690
-
Predicting response to treatment in gastroesophageal junction adenocarcinomas: Combining clinical, imaging, and molecular biomarkers
-
Bain GH, Petty RD (2010) Predicting response to treatment in gastroesophageal junction adenocarcinomas: combining clinical, imaging, and molecular biomarkers. Oncologist 15: 270-284.
-
(2010)
Oncologist
, vol.15
, pp. 270-284
-
-
Bain, G.H.1
Petty, R.D.2
-
7
-
-
84865849441
-
Targeted therapy for gastric adenocarcinoma
-
Almhanna K (2012) Targeted therapy for gastric adenocarcinoma. Adv Pharmacol 65: 437-470.
-
(2012)
Adv Pharmacol
, vol.65
, pp. 437-470
-
-
Almhanna, K.1
-
8
-
-
84863506850
-
Molecular targeted agents for gastric and gastroesophageal junction cancer
-
Oshima T, Masuda M (2012) Molecular targeted agents for gastric and gastroesophageal junction cancer. Surg Today 42: 313-327.
-
(2012)
Surg Today
, vol.42
, pp. 313-327
-
-
Oshima, T.1
Masuda, M.2
-
9
-
-
78649332138
-
Esophageal adenocarcinoma: Treatment modalities in the era of targeted therapy
-
Mukherjee K, Chakravarthy AB, Goff LW, El-Rifai W (2010) Esophageal adenocarcinoma: treatment modalities in the era of targeted therapy. Dig Dis Sci 55: 3304-3314.
-
(2010)
Dig Dis Sci
, vol.55
, pp. 3304-3314
-
-
Mukherjee, K.1
Chakravarthy, A.B.2
Goff, L.W.3
El-Rifai, W.4
-
10
-
-
77953590185
-
PAK1 as a therapeutic target
-
Kichina JV, Goc A, Al-Husein B, Somanath PR, Kandel ES (2010) PAK1 as a therapeutic target. Expert Opin Ther Targets 14: 703-725.
-
(2010)
Expert Opin Ther Targets
, vol.14
, pp. 703-725
-
-
Kichina, J.V.1
Goc, A.2
Al-Husein, B.3
Somanath, P.R.4
Kandel, E.S.5
-
11
-
-
84884477715
-
The PAKs come of age: Celebrating 18 years of discovery
-
Field J, Manser E (2012) The PAKs come of age: Celebrating 18 years of discovery. Cell Logist 2: 54-58.
-
(2012)
Cell Logist
, vol.2
, pp. 54-58
-
-
Field, J.1
Manser, E.2
-
12
-
-
84876011758
-
PAK signaling in cancer
-
Ye DZ, Field J (2012) PAK signaling in cancer. Cell Logist 2: 105-116.
-
(2012)
Cell Logist
, vol.2
, pp. 105-116
-
-
Ye, D.Z.1
Field, J.2
-
14
-
-
0030612748
-
Rho effecters and reorganization of actin cytoskeleton
-
DOI 10.1016/S0014-5793(97)00317-7, PII S0014579397003177
-
Narumiya S, Ishizaki T, Watanabe N (1997) Rho effectors and reorganization of actin cytoskeleton. FEBS Lett 410: 68-72. (Pubitemid 27283386)
-
(1997)
FEBS Letters
, vol.410
, Issue.1
, pp. 68-72
-
-
Narumiya, S.1
Ishizaki, T.2
Watanabe, N.3
-
15
-
-
0034671927
-
Vascular endothelial growth factor up-regulation via p21-activated kinase-1 signaling regulates heregulin-beta1-mediated angiogenesis
-
DOI 10.1074/jbc.M006150200
-
Bagheri-Yarmand R, Vadlamudi RK, Wang RA, Mendelsohn J, Kumar R (2000) Vascular endothelial growth factor up-regulation via p21-activated kinase-1 signaling regulates heregulin-beta1-mediated angiogenesis. J Biol Chem 275: 39451-39457. (Pubitemid 32058970)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.50
, pp. 39451-39457
-
-
Bagheri-Yarmand, R.1
Vadlamudi, R.K.2
Wang, R.-A.3
Mendelsohn, J.4
Kumar, R.5
-
16
-
-
84863968373
-
Molecular pathways: Targeting p21-activated kinase 1 signaling in cancer-opportunities, challenges, and limitations
-
Eswaran J, Li DQ, Shah A, Kumar R (2012) Molecular pathways: targeting p21-activated kinase 1 signaling in cancer-opportunities, challenges, and limitations. Clin Cancer Res 18: 3743-3749.
-
(2012)
Clin Cancer Res
, vol.18
, pp. 3743-3749
-
-
Eswaran, J.1
Li, D.Q.2
Shah, A.3
Kumar, R.4
-
17
-
-
2642521235
-
Overexpression of HER2 (erbB2) in human breast epithelial cells unmasks transforming growth factor beta-induced cell motility
-
DOI 10.1074/jbc.M400081200
-
Ueda Y, Wang S, Dumont N, Yi JY, Koh Y, et al. (2004) Overexpression of HER2 (erbB2) in human breast epithelial cells unmasks transforming growth factor beta-induced cell motility. J Biol Chem 279: 24505-24513. (Pubitemid 38725316)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.23
, pp. 24505-24513
-
-
Ueda, Y.1
Wang, S.2
Dumont, N.3
Yi, J.Y.4
Koh, Y.5
Arteaga, C.L.6
-
18
-
-
33750324597
-
HER2/Neu (ErbB2) signaling to Rac1-Pak1 is temporally and spatially modulated by transforming growth factor beta
-
DOI 10.1158/0008-5472.CAN-06-2071
-
Wang SE, Shin I, Wu FY, Friedman DB, Arteaga CL (2006) HER2/Neu (ErbB2) signaling to Rac1-Pak1 is temporally and spatially modulated by transforming growth factor beta. Cancer research 66: 9591-9600. (Pubitemid 44623658)
-
(2006)
Cancer Research
, vol.66
, Issue.19
, pp. 9591-9600
-
-
Wang, S.E.1
Shin, I.2
Wu, F.Y.3
Friedman, D.B.4
Arteaga, C.L.5
-
19
-
-
78049337472
-
A Rac-Pak signaling pathway is essential for ErbB2-mediated transformation of human breast epithelial cancer cells
-
Arias-Romero LE, Villamar-Cruz O, Pacheco A, Kosoff R, Huang M, et al. (2010) A Rac-Pak signaling pathway is essential for ErbB2-mediated transformation of human breast epithelial cancer cells. Oncogene 29: 5839-5849.
-
(2010)
Oncogene
, vol.29
, pp. 5839-5849
-
-
Arias-Romero, L.E.1
Villamar-Cruz, O.2
Pacheco, A.3
Kosoff, R.4
Huang, M.5
-
20
-
-
84872873855
-
Thrombin stimulation of inflammatory breast cancer cells leads to aggressiveness via the EGFR-PAR1-Pak1 pathway
-
Ohshiro K, Bui-Nguyen TM, Divijendra Natha RS, Schwartz AM, Levine P, et al. (2012) Thrombin stimulation of inflammatory breast cancer cells leads to aggressiveness via the EGFR-PAR1-Pak1 pathway. Int J Biol Markers 27: e305-313.
-
(2012)
Int J Biol Markers
, vol.27
-
-
Ohshiro, K.1
Bui-Nguyen, T.M.2
Divijendra Natha, R.S.3
Schwartz, A.M.4
Levine, P.5
-
21
-
-
2542452838
-
Pak-1 expression increases with progression of colorectal carcinomas to metastasis
-
Carter JH, Douglass LE, Deddens JA, Colligan BM, Bhatt TR, et al. (2004) Pak-1 expression increases with progression of colorectal carcinomas to metastasis. Clinical cancer research: an official journal of the American Association for Cancer Research 10: 3448-3456.
-
(2004)
Clinical Cancer Research: An Official Journal of the American Association for Cancer Research
, vol.10
, pp. 3448-3456
-
-
Carter, J.H.1
Douglass, L.E.2
Deddens, J.A.3
Colligan, B.M.4
Bhatt, T.R.5
-
22
-
-
33646682385
-
PAK1 hyperactivation is sufficient for mammary gland tumor formation
-
DOI 10.1038/sj.onc.1209309, PII 1209309
-
Wang RA, Zhang H, Balasenthil S, Medina D, Kumar R (2006) PAK1 hyperactivation is sufficient for mammary gland tumor formation. Oncogene 25: 2931-2936. (Pubitemid 43739243)
-
(2006)
Oncogene
, vol.25
, Issue.20
, pp. 2931-2936
-
-
Wang, R.-A.1
Zhang, H.2
Balasenthil, S.3
Medina, D.4
Kumar, R.5
-
23
-
-
34248531653
-
P21-Activated Protein Kinase Is Overexpressed in Hepatocellular Carcinoma and Enhances Cancer Metastasis Involving c-Jun NH2-Terminal Kinase Activation and Paxillin Phosphorylation
-
Ching YP, Leong VY, Lee MF, Xu HT, Jin DY, et al. (2007) P21-Activated Protein Kinase Is Overexpressed in Hepatocellular Carcinoma and Enhances Cancer Metastasis Involving c-Jun NH2-Terminal Kinase Activation and Paxillin Phosphorylation Cancer research 67: 3601-3608.
-
(2007)
Cancer Research
, vol.67
, pp. 3601-3608
-
-
Ching, Y.P.1
Leong, V.Y.2
Lee, M.F.3
Xu, H.T.4
Jin, D.Y.5
-
24
-
-
77956514340
-
P21-activated protein kinase 1 induces colorectal cancer metastasis involving ERK activation and phosphorylation of FAK at Ser-910
-
Li LH, Zheng MH, Luo Q, Ye Q, Feng B, et al. (2010) P21-activated protein kinase 1 induces colorectal cancer metastasis involving ERK activation and phosphorylation of FAK at Ser-910. Int J Oncol 37: 951-962.
-
(2010)
Int J Oncol
, vol.37
, pp. 951-962
-
-
Li, L.H.1
Zheng, M.H.2
Luo, Q.3
Ye, Q.4
Feng, B.5
-
25
-
-
84863247385
-
P21-activated protein kinase 1 is overexpressed in gastric cancer and induces cancer metastasis
-
Li LH, Luo Q, Zheng MH, Pan C, Wu GY, et al. (2012) P21-activated protein kinase 1 is overexpressed in gastric cancer and induces cancer metastasis. Oncol Rep 27: 1435-1442.
-
(2012)
Oncol Rep
, vol.27
, pp. 1435-1442
-
-
Li, L.H.1
Luo, Q.2
Zheng, M.H.3
Pan, C.4
Wu, G.Y.5
-
26
-
-
84864123373
-
PAK1 is a breast cancer oncogene that coordinately activates MAPK and MET signaling
-
Shrestha Y, Schafer EJ, Boehm JS, Thomas SR, He F, et al. (2012) PAK1 is a breast cancer oncogene that coordinately activates MAPK and MET signaling. Oncogene 31: 3397-3408.
-
(2012)
Oncogene
, vol.31
, pp. 3397-3408
-
-
Shrestha, Y.1
Schafer, E.J.2
Boehm, J.S.3
Thomas, S.R.4
He, F.5
-
27
-
-
16844377441
-
Pak1 phosphorylation of Snail, a master regulator of epithelial-to- mesenchyme transition, modulates Snail's subcellular localization and functions
-
Yang Z, Rayala S, Nguyen D, Vadlamudi RK, Chen S, et al. (2005) Pak1 phosphorylation of snail, a master regulator of epithelial-to-mesenchyme transition, modulates snail's subcellular localization and functions. Cancer Res 65: 3179-3184. (Pubitemid 40524599)
-
(2005)
Cancer Research
, vol.65
, Issue.8
, pp. 3179-3184
-
-
Yang, Z.1
Rayala, S.2
Nguyen, D.3
Vadlamudi, R.K.4
Chen, S.5
Kumar, R.6
-
28
-
-
79955568142
-
Targeting p21-activated kinase 1 (PAK1) to induce apoptosis of tumor cells
-
Ong CC, Jubb AM, Haverty PM, Zhou W, Tran V, et al. (2011) Targeting p21-activated kinase 1 (PAK1) to induce apoptosis of tumor cells. Proc Natl Acad Sci U S A 108: 7177-7182.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 7177-7182
-
-
Ong, C.C.1
Jubb, A.M.2
Haverty, P.M.3
Zhou, W.4
Tran, V.5
-
29
-
-
0034604338
-
Structure of PAK1 in an autoinhibited conformation reveals a multistage activation switch
-
Lei M, Lu W, Meng W, Parrini MC, Eck MJ, et al. (2000) Structure of PAK1 in an autoinhibited conformation reveals a multistage activation switch. Cell 102: 387-397.
-
(2000)
Cell
, vol.102
, pp. 387-397
-
-
Lei, M.1
Lu, W.2
Meng, W.3
Parrini, M.C.4
Eck, M.J.5
-
30
-
-
34547433543
-
Inhibition of p21-activated kinase rescues symptoms of fragile X syndrome in mice
-
DOI 10.1073/pnas.0705003104
-
Hayashi ML, Rao BS, Seo JS, Choi HS, Dolan BM, et al. (2007) Inhibition of p21-activated kinase rescues symptoms of fragile X syndrome in mice. Proc Natl Acad Sci U S A 104: 11489-11494. (Pubitemid 47175167)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.27
, pp. 11489-11494
-
-
Hayashi, M.L.1
Rao, B.S.S.2
Seo, J.-S.3
Choi, H.-S.4
Dolan, B.M.5
Choi, S.-Y.6
Chattarji, S.7
Tonegawa, S.8
-
31
-
-
76249092901
-
Curcumin suppresses proliferation and invasion in human gastric cancer cells by downregulation of PAK1 activity and cyclin D1 expression
-
Cai XZ, Wang J, Li XD, Wang GL, Liu FN, et al. (2009) Curcumin suppresses proliferation and invasion in human gastric cancer cells by downregulation of PAK1 activity and cyclin D1 expression. Cancer Biol Ther 8: 1360-1368.
-
(2009)
Cancer Biol Ther
, vol.8
, pp. 1360-1368
-
-
Cai, X.Z.1
Wang, J.2
Li, X.D.3
Wang, G.L.4
Liu, F.N.5
-
32
-
-
84868626073
-
The response to PAK1 inhibitor IPA3 distinguishes between cancer cells with mutations in BRAF and Ras oncogenes
-
Singhal R, Kandel ES (2012) The response to PAK1 inhibitor IPA3 distinguishes between cancer cells with mutations in BRAF and Ras oncogenes. Oncotarget 3: 700-708.
-
(2012)
Oncotarget
, vol.3
, pp. 700-708
-
-
Singhal, R.1
Kandel, E.S.2
-
33
-
-
84868547553
-
p21-activated kinases and gastrointestinal cancer
-
He H, Baldwin GS (2013) p21-activated kinases and gastrointestinal cancer. Biochim Biophys Acta 1833: 33-39.
-
(2013)
Biochim Biophys Acta
, vol.1833
, pp. 33-39
-
-
He, H.1
Baldwin, G.S.2
-
34
-
-
33846846632
-
Temporal trends of esophageal cancer during 1995-2004 in Nanao Island, an extremely high-risk area in China
-
DOI 10.1007/s10654-006-9086-x
-
Su M, Liu M, Tian DP, Li XY, Zhang GH, et al. (2007) Temporal trends of esophageal cancer during 1995-2004 in Nanao Island, an extremely high-risk area in China. Eur J Epidemiol 22: 43-48. (Pubitemid 46208245)
-
(2007)
European Journal of Epidemiology
, vol.22
, Issue.1
, pp. 43-48
-
-
Su, M.1
Liu, M.2
Tian, D.-P.3
Li, X.-Y.4
Zhang, G.-H.5
Yang, H.-L.6
Fan, X.7
Huang, H.-H.8
Gao, Y.-X.9
-
35
-
-
84875217023
-
Esophagus or stomach? The seventh TNM classification for Siewert type II/III junctional adenocarcinoma
-
Hasegawa S, Yoshikawa T, Aoyama T, Hayashi T, Yamada T, et al. (2013) Esophagus or stomach? The seventh TNM classification for Siewert type II/III junctional adenocarcinoma. Ann Surg Oncol 20: 773-779.
-
(2013)
Ann Surg Oncol
, vol.20
, pp. 773-779
-
-
Hasegawa, S.1
Yoshikawa, T.2
Aoyama, T.3
Hayashi, T.4
Yamada, T.5
-
36
-
-
78650865669
-
Gastric cardiac carcinomas involving the esophagus are more adequately staged as gastric cancers by the 7th edition of the American Joint Commission on Cancer Staging System
-
Huang Q, Shi J, Feng A, Fan X, Zhang L, et al. (2011) Gastric cardiac carcinomas involving the esophagus are more adequately staged as gastric cancers by the 7th edition of the American Joint Commission on Cancer Staging System. Mod Pathol 24: 138-146.
-
(2011)
Mod Pathol
, vol.24
, pp. 138-146
-
-
Huang, Q.1
Shi, J.2
Feng, A.3
Fan, X.4
Zhang, L.5
-
37
-
-
1642377561
-
ONCOMINE: A Cancer Microarray Database and Integrated Data-Mining Platform
-
Rhodes DR, Yu J, Shanker K, Deshpande N, Varambally R, et al. (2004) ONCOMINE: a cancer microarray database and integrated data-mining platform. Neoplasia 6: 1-6. (Pubitemid 38391943)
-
(2004)
Neoplasia
, vol.6
, Issue.1
, pp. 1-6
-
-
Rhodes, D.R.1
Yu, J.2
Shanker, K.3
Deshpande, N.4
Varambally, R.5
Ghosh, D.6
Barrette, T.7
Pandey, A.8
Chinnaiyan, A.M.9
-
38
-
-
0035887459
-
Molecular classification of human carcinomas by use of gene expression signatures
-
Su AI, Welsh JB, Sapinoso LM, Kern SG, Dimitrov P, et al. (2001) Molecular classification of human carcinomas by use of gene expression signatures. Cancer Res 61: 7388-7393. (Pubitemid 32995021)
-
(2001)
Cancer Research
, vol.61
, Issue.20
, pp. 7388-7393
-
-
Su, A.I.1
Welsh, J.B.2
Sapinoso, L.M.3
Kern, S.G.4
Dimitrov, P.5
Lapp, H.6
Schultz, P.G.7
Powell, S.M.8
Moskaluk, C.A.9
Frierson Jr., H.F.10
Hampton, G.M.11
-
39
-
-
77953805124
-
Genetic profiles of gastroesophageal cancer: Combined analysis using expression array and tiling array-comparative genomic hybridization
-
Isinger-Ekstrand A, Johansson J, Ohlsson M, Francis P, Staaf J, et al. (2010) Genetic profiles of gastroesophageal cancer: combined analysis using expression array and tiling array-comparative genomic hybridization. Cancer Genet Cytogenet 200: 120-126.
-
(2010)
Cancer Genet Cytogenet
, vol.200
, pp. 120-126
-
-
Isinger-Ekstrand, A.1
Johansson, J.2
Ohlsson, M.3
Francis, P.4
Staaf, J.5
-
40
-
-
0032441150
-
Cluster analysis and display of genome-wide expression patterns
-
DOI 10.1073/pnas.95.25.14863
-
Eisen MB, Spellman PT, Brown PO, Botstein D (1998) Cluster analysis and display of genome-wide expression patterns. Proc Natl Acad Sci U S A 95: 14863-14868. (Pubitemid 29003722)
-
(1998)
Proceedings of the National Academy of Sciences of the United States of America
, vol.95
, Issue.25
, pp. 14863-14868
-
-
Eisen, M.B.1
Spellman, P.T.2
Brown, P.O.3
Botstein, D.4
-
41
-
-
0035949683
-
+-pump
-
DOI 10.1073/pnas.191389398
-
Gaxiola RA, Li J, Undurraga S, Dang LM, Allen GJ, et al. (2001) Drought- and salt-tolerant plants result from overexpression of the AVP1 H+-pump. Proc Natl Acad Sci U S A 98: 11444-11449. (Pubitemid 32928748)
-
(2001)
Proceedings of the National Academy of Sciences of the United States of America
, vol.98
, Issue.20
, pp. 11444-11449
-
-
Gaxiola, R.A.1
Li, J.2
Undurraga, S.3
Dang, L.M.4
Allen, G.J.5
Alper, S.L.6
Fink, G.R.7
-
42
-
-
84875226458
-
MicroRNA-7 functions as an anti-metastatic microRNA in gastric cancer by targeting insulin-like growth factor-1 receptor
-
Zhao X, Dou W, He L, Liang S, Tie J, et al. (2012) MicroRNA-7 functions as an anti-metastatic microRNA in gastric cancer by targeting insulin-like growth factor-1 receptor. Oncogene.
-
(2012)
Oncogene
-
-
Zhao, X.1
Dou, W.2
He, L.3
Liang, S.4
Tie, J.5
-
43
-
-
0023710206
-
Comparing the areas under two or more correlated receiver operating characteristic curves: A nonparametric approach
-
DeLong ER, DeLong DM, Clarke-Pearson DL (1988) Comparing the areas under two or more correlated receiver operating characteristic curves: a nonparametric approach. Biometrics 44: 837-845.
-
(1988)
Biometrics
, vol.44
, pp. 837-845
-
-
DeLong, E.R.1
DeLong, D.M.2
Clarke-Pearson, D.L.3
-
44
-
-
84871229995
-
Trastuzumab: Updated mechanisms of action and resistance in breast cancer
-
Vu T, Claret FX (2012) Trastuzumab: updated mechanisms of action and resistance in breast cancer. Front Oncol 2: 62.
-
(2012)
Front Oncol
, vol.2
, pp. 62
-
-
Vu, T.1
Claret, F.X.2
-
45
-
-
84862553312
-
Molecular Mechanisms of Trastuzumab Resistance in HER2 Overexpressing Breast Cancer
-
Fiszman GL, Jasnis MA (2011) Molecular Mechanisms of Trastuzumab Resistance in HER2 Overexpressing Breast Cancer. Int J Breast Cancer 2011: 352182.
-
(2011)
Int J Breast Cancer
, vol.2011
, pp. 352182
-
-
Fiszman, G.L.1
Jasnis, M.A.2
-
46
-
-
77953500567
-
Differences underlying EGFR and HER2 oncogene addiction
-
Faber AC, Wong KK, Engelman JA (2010) Differences underlying EGFR and HER2 oncogene addiction. Cell Cycle 9: 851-852.
-
(2010)
Cell Cycle
, vol.9
, pp. 851-852
-
-
Faber, A.C.1
Wong, K.K.2
Engelman, J.A.3
-
47
-
-
60749085908
-
Overcoming resistance to tyrosine kinase inhibitors: Lessons learned from cancer cells treated with EGFR antagonists
-
Rexer BN, Engelman JA, Arteaga CL (2009) Overcoming resistance to tyrosine kinase inhibitors: lessons learned from cancer cells treated with EGFR antagonists. Cell Cycle 8: 18-22.
-
(2009)
Cell Cycle
, vol.8
, pp. 18-22
-
-
Rexer, B.N.1
Engelman, J.A.2
Arteaga, C.L.3
-
48
-
-
62649157431
-
ErbB receptors in the biology and pathology of the aerodigestive tract
-
Morgan S, Grandis JR (2009) ErbB receptors in the biology and pathology of the aerodigestive tract. Exp Cell Res 315: 572-582.
-
(2009)
Exp Cell Res
, vol.315
, pp. 572-582
-
-
Morgan, S.1
Grandis, J.R.2
-
49
-
-
33845240595
-
Molecular basis for sensitivity and acquired resistance to gefitinib in HER2-overexpressing human gastric cancer cell lines derived from liver metastasis
-
DOI 10.1038/sj.bjc.6603459, PII 6603459
-
Yokoyama H, Ikehara Y, Kodera Y, Ikehara S, Yatabe Y, et al. (2006) Molecular basis for sensitivity and acquired resistance to gefitinib in HER2-overexpressing human gastric cancer cell lines derived from liver metastasis. Br J Cancer 95: 1504-1513. (Pubitemid 44863353)
-
(2006)
British Journal of Cancer
, vol.95
, Issue.11
, pp. 1504-1513
-
-
Yokoyama, H.1
Ikehara, Y.2
Kodera, Y.3
Ikehara, S.4
Yatabe, Y.5
Mochizuki, Y.6
Koike, M.7
Fujiwara, M.8
Nakao, A.9
Tatematsu, M.10
Nakanishi, H.11
-
50
-
-
81755161341
-
HER2 testing in gastric and gastroesophageal junction cancers: A new therapeutic target and diagnostic challenge
-
Hicks DG, Whitney-Miller C (2011) HER2 testing in gastric and gastroesophageal junction cancers: a new therapeutic target and diagnostic challenge. Appl Immunohistochem Mol Morphol 19: 506-508.
-
(2011)
Appl Immunohistochem Mol Morphol
, vol.19
, pp. 506-508
-
-
Hicks, D.G.1
Whitney-Miller, C.2
-
51
-
-
0032561206
-
Heregulin regulates cytoskeletal reorganization and cell migration through the p21-activated kinase-1 via phosphatidylinositol-3 kinase
-
DOI 10.1074/jbc.273.43.28238
-
Adam L, Vadlamudi R, Kondapaka SB, Chernoff J, Mendelsohn J, et al. (1998) Heregulin regulates cytoskeletal reorganization and cell migration through the p21-activated kinase-1 via phosphatidylinositol-3 kinase. J Biol Chem 273: 28238-28246. (Pubitemid 28496122)
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.43
, pp. 28238-28246
-
-
Adam, L.1
Vadlamudi, R.2
Kondapaka, S.B.3
Chernoff, J.4
Mendelsohn, J.5
Kumar, R.6
-
52
-
-
0028946573
-
Obesity, alcohol, and tobacco as risk factors for cancers of the esophagus and gastric cardia: Adenocarcinoma versus squamous cell carcinoma
-
Vaughan TL, Davis S, Kristal A, Thomas DB (1995) Obesity, alcohol, and tobacco as risk factors for cancers of the esophagus and gastric cardia: adenocarcinoma versus squamous cell carcinoma. Cancer Epidemiol Biomarkers Prev 4: 85-92.
-
(1995)
Cancer Epidemiol Biomarkers Prev
, vol.4
, pp. 85-92
-
-
Vaughan, T.L.1
Davis, S.2
Kristal, A.3
Thomas, D.B.4
-
53
-
-
68549135302
-
Predictive value of initial PET-SUVmax in patients with locally advanced esophageal and gastroesophageal junction adenocarcinoma
-
Rizk NP, Tang L, Adusumilli PS, Bains MS, Akhurst TJ, et al. (2009) Predictive value of initial PET-SUVmax in patients with locally advanced esophageal and gastroesophageal junction adenocarcinoma. J Thorac Oncol 4: 875-879.
-
(2009)
J Thorac Oncol
, vol.4
, pp. 875-879
-
-
Rizk, N.P.1
Tang, L.2
Adusumilli, P.S.3
Bains, M.S.4
Akhurst, T.J.5
-
54
-
-
51649087089
-
Does neoadjuvant treatment for gastric cancer patients with positive peritoneal cytology at staging laparoscopy improve survival?
-
Badgwell B, Cormier JN, Krishnan S, Yao J, Staerkel GA, et al. (2008) Does neoadjuvant treatment for gastric cancer patients with positive peritoneal cytology at staging laparoscopy improve survival? Ann Surg Oncol 15: 2684-2691.
-
(2008)
Ann Surg Oncol
, vol.15
, pp. 2684-2691
-
-
Badgwell, B.1
Cormier, J.N.2
Krishnan, S.3
Yao, J.4
Staerkel, G.A.5
-
55
-
-
33846629672
-
Multicenter phase II study of irinotecan, cisplatin, and bevacizumab in patients with metastatic gastric or gastroesophageal junction adenocarcinoma
-
DOI 10.1200/JCO.2006.08.0887
-
Shah MA, Ramanathan RK, Ilson DH, Levnor A, D'Adamo D, et al. (2006) Multicenter phase II study of irinotecan, cisplatin, and bevacizumab in patients with metastatic gastric or gastroesophageal junction adenocarcinoma. J Clin Oncol 24: 5201-5206. (Pubitemid 46631363)
-
(2006)
Journal of Clinical Oncology
, vol.24
, Issue.33
, pp. 5201-5206
-
-
Shah, M.A.1
Ramanathan, R.K.2
Ilson, D.H.3
Levnor, A.4
D'Adamo, D.5
O'Reilly, E.6
Tse, A.7
Trocola, R.8
Schwartz, L.9
Capanu, M.10
Schwartz, G.K.11
Kelsen, D.P.12
-
56
-
-
10744219536
-
The Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor ZD1839 (Iressa) Suppresses c-Src and Pak1 Pathways and Invasiveness of Human Cancer Cells
-
DOI 10.1158/1078-0432.CCR-0382-03
-
Yang Z, Bagheri-Yarmand R, Wang RA, Adam L, Papadimitrakopoulou VV, et al. (2004) The epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 (Iressa) suppresses c-Src and Pak1 pathways and invasiveness of human cancer cells. Clin Cancer Res 10: 658-667. (Pubitemid 38174006)
-
(2004)
Clinical Cancer Research
, vol.10
, Issue.2
, pp. 658-667
-
-
Yang, Z.1
Bagheri-Yarmand, R.2
Wang, R.-A.3
Adam, L.4
Papadimitrakopoulou, V.V.5
Clayman, G.L.6
El-Naggar, A.7
Lotan, R.8
Barnes, C.J.9
Hong, W.K.10
Kumar, R.11
-
57
-
-
77956262693
-
Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): A phase 3, open-label, randomised controlled trial
-
Bang YJ, Van Cutsem E, Feyereislova A, Chung HC, Shen L, et al. (2010) Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): a phase 3, open-label, randomised controlled trial. Lancet 376: 687-697.
-
(2010)
Lancet
, vol.376
, pp. 687-697
-
-
Bang, Y.J.1
Van Cutsem, E.2
Feyereislova, A.3
Chung, H.C.4
Shen, L.5
-
58
-
-
70350714440
-
Downregulation of p21-activated kinase-1 inhibits the growth of gastric cancer cells involving cyclin B1
-
Liu F, Li X, Wang C, Cai X, Du Z, et al. (2009) Downregulation of p21-activated kinase-1 inhibits the growth of gastric cancer cells involving cyclin B1. International journal of cancer Journal international du cancer 125: 2511-2519.
-
(2009)
International Journal of Cancer Journal International du Cancer
, vol.125
, pp. 2511-2519
-
-
Liu, F.1
Li, X.2
Wang, C.3
Cai, X.4
Du, Z.5
-
59
-
-
77953186827
-
Prognostic significance of genetic alterations detected by high-density single nucleotide polymorphism array in gastric cancer
-
Tada M, Kanai F, Tanaka Y, Sanada M, Nannya Y, et al. (2010) Prognostic significance of genetic alterations detected by high-density single nucleotide polymorphism array in gastric cancer. Cancer Sci 101: 1261-1269.
-
(2010)
Cancer Sci
, vol.101
, pp. 1261-1269
-
-
Tada, M.1
Kanai, F.2
Tanaka, Y.3
Sanada, M.4
Nannya, Y.5
-
60
-
-
84862654141
-
Genome-wide screening for genetic alterations in esophageal cancer by aCGH identifies 11q13 amplification oncogenes associated with nodal metastasis
-
Ying J, Shan L, Li J, Zhong L, Xue L, et al. (2012) Genome-wide screening for genetic alterations in esophageal cancer by aCGH identifies 11q13 amplification oncogenes associated with nodal metastasis. PLoS One 7: e39797.
-
(2012)
PLoS One
, vol.7
-
-
Ying, J.1
Shan, L.2
Li, J.3
Zhong, L.4
Xue, L.5
-
61
-
-
84862742319
-
Hepatitis B virus X protein confers resistance of hepatoma cells to anoikis by up-regulating and activating p21-activated kinase 1
-
Xu J, Liu H, Chen L, Wang S, Zhou L, et al. (2012) Hepatitis B virus X protein confers resistance of hepatoma cells to anoikis by up-regulating and activating p21-activated kinase 1. Gastroenterology 143: 199-212 e194.
-
(2012)
Gastroenterology
, vol.143
-
-
Xu, J.1
Liu, H.2
Chen, L.3
Wang, S.4
Zhou, L.5
-
62
-
-
77649091619
-
Estrogen receptor-alpha phosphorylation at serine 305, nuclear p21-activated kinase 1 expression, and response to tamoxifen in postmenopausal breast cancer
-
Bostner J, Skoog L, Fornander T, Nordenskjold B, Stal O (2010) Estrogen receptor-alpha phosphorylation at serine 305, nuclear p21-activated kinase 1 expression, and response to tamoxifen in postmenopausal breast cancer. Clinical cancer research: an official journal of the American Association for Cancer Research 16: 1624-1633.
-
(2010)
Clinical Cancer Research: An Official Journal of the American Association for Cancer Research
, vol.16
, pp. 1624-1633
-
-
Bostner, J.1
Skoog, L.2
Fornander, T.3
Nordenskjold, B.4
Stal, O.5
-
63
-
-
70350714440
-
Downregulation of p21-activated kinase-1 inhibits the growth of gastric cancer cells involving cyclin B1
-
Liu F, Li X, Wang C, Cai X, Du Z, et al. (2009) Downregulation of p21-activated kinase-1 inhibits the growth of gastric cancer cells involving cyclin B1. Int J Cancer 125: 2511-2519.
-
(2009)
Int J Cancer
, vol.125
, pp. 2511-2519
-
-
Liu, F.1
Li, X.2
Wang, C.3
Cai, X.4
Du, Z.5
-
64
-
-
79956137341
-
Potential role of minichromosome maintenance protein 2 as a screening biomarker in esophageal cancer high-risk population in China
-
Huang B, Hu B, Su M, Tian D, Guo Y, et al. (2011) Potential role of minichromosome maintenance protein 2 as a screening biomarker in esophageal cancer high-risk population in China. Hum Pathol 42: 808-816.
-
(2011)
Hum Pathol
, vol.42
, pp. 808-816
-
-
Huang, B.1
Hu, B.2
Su, M.3
Tian, D.4
Guo, Y.5
-
65
-
-
40149107735
-
Analysis of basement membrane structure and inflammation during the development of esophageal squamous cell carcinoma in the Chinese Chaoshan high risk region
-
DOI 10.1080/07357900701683901, PII 790382366
-
Zhang GH, Su M, Tian DP, Huang HH, Wu XY, et al. (2008) Analysis of basement membrane structure and inflammation during the development of esophageal squamous cell carcinoma in the Chinese Chaoshan high risk region. Cancer Invest 26: 296-305. (Pubitemid 351329004)
-
(2008)
Cancer Investigation
, vol.26
, Issue.3
, pp. 296-305
-
-
Zhang, G.-H.1
Su, M.2
Tian, D.-P.3
Huang, H.-H.4
Wu, X.-Y.5
Zheng, R.-M.6
Li, Q.-S.7
-
66
-
-
56549110778
-
Changing trends in the proportion of adenocarcinoma of the esophagogastric junction in a large tertiary referral center in Japan
-
Kusano C, Gotoda T, Khor CJ, Katai H, Kato H, et al. (2008) Changing trends in the proportion of adenocarcinoma of the esophagogastric junction in a large tertiary referral center in Japan. J Gastroenterol Hepatol 23: 1662-1665.
-
(2008)
J Gastroenterol Hepatol
, vol.23
, pp. 1662-1665
-
-
Kusano, C.1
Gotoda, T.2
Khor, C.J.3
Katai, H.4
Kato, H.5
|