메뉴 건너뛰기




Volumn 55, Issue 12, 2010, Pages 3304-3314

Esophageal adenocarcinoma: Treatment modalities in the era of targeted therapy

Author keywords

Cancer; Esophageal; Radiation; Surgery; Targets; Therapy

Indexed keywords

1 CYCLOPROPYL 3 [3 (5 MORPHOLINOMETHYL 1H BENZIMIDAZOL 2 YL) 1H PYRAZOL 4 YL]UREA; ANTINEOPLASTIC AGENT; BEVACIZUMAB; BRIVANIB; CARBOPLATIN; CETUXIMAB; CISPLATIN; DOCETAXEL; EPIRUBICIN; ERLOTINIB; FLUOROPYRIMIDINE; FLUOROURACIL; GEFITINIB; IMATINIB; IRINOTECAN; LAPATINIB; MATUZUMAB; MK 0547; MLN 8237; OBLIMERSEN; OXALIPLATIN; PACLITAXEL; PANITUMUMAB; SORAFENIB; SUNITINIB; TRASTUZUMAB; UNCLASSIFIED DRUG; UNINDEXED DRUG; VANDETANIB; VE 465; VORINOSTAT;

EID: 78649332138     PISSN: 01632116     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10620-010-1187-4     Document Type: Review
Times cited : (9)

References (119)
  • 1
    • 13744258445 scopus 로고    scopus 로고
    • The role of overdiagnosis and reclassification in the marked increase of esophageal adenocarcinoma incidence
    • 15657344
    • H Pohl HG Welch 2005 The role of overdiagnosis and reclassification in the marked increase of esophageal adenocarcinoma incidence J Natl Cancer Inst 97 2 142 146 15657344
    • (2005) J Natl Cancer Inst , vol.97 , Issue.2 , pp. 142-146
    • Pohl, H.1    Welch, H.G.2
  • 2
    • 51049091878 scopus 로고    scopus 로고
    • Incidence of adenocarcinoma of the esophagus among white Americans by sex, stage, and age
    • 18695138
    • LM Brown SS Devesa WH Chow 2008 Incidence of adenocarcinoma of the esophagus among white Americans by sex, stage, and age J Natl Cancer Inst 100 16 1184 1187 18695138
    • (2008) J Natl Cancer Inst , vol.100 , Issue.16 , pp. 1184-1187
    • Brown, L.M.1    Devesa, S.S.2    Chow, W.H.3
  • 3
    • 0032533670 scopus 로고    scopus 로고
    • Changing patterns in the incidence of esophageal and gastric carcinoma in the United States
    • 1:STN:280:DyaK1M%2FktlCjuw%3D%3D 9827707
    • SS Devesa WJ Blot JF Fraumeni Jr 1998 Changing patterns in the incidence of esophageal and gastric carcinoma in the United States Cancer 83 10 2049 2053 1:STN:280:DyaK1M%2FktlCjuw%3D%3D 9827707
    • (1998) Cancer , vol.83 , Issue.10 , pp. 2049-2053
    • Devesa, S.S.1    Blot, W.J.2    Fraumeni Jr., J.F.3
  • 4
    • 52449108090 scopus 로고    scopus 로고
    • Acid, bile, and CDX: The abcs of making Barrett's metaplasia
    • 1:CAS:528:DC%2BD1cXhtVaktrjJ 18556417
    • RF Souza K Krishnan SJ Spechler 2008 Acid, bile, and CDX: the abcs of making Barrett's metaplasia Am J Physiol Gastrointest Liver Physiol 295 2 G211 G218 1:CAS:528:DC%2BD1cXhtVaktrjJ 18556417
    • (2008) Am J Physiol Gastrointest Liver Physiol , vol.295 , Issue.2
    • Souza, R.F.1    Krishnan, K.2    Spechler, S.J.3
  • 5
    • 59549100166 scopus 로고    scopus 로고
    • Esophageal adenocarcinoma arising in Barrett esophagus
    • 1:CAS:528:DC%2BD1MXhsFOmu78%3D 18703277
    • HY Zhang SJ Spechler RF Souza 2009 Esophageal adenocarcinoma arising in Barrett esophagus Cancer Lett 275 2 170 177 1:CAS:528:DC%2BD1MXhsFOmu78%3D 18703277
    • (2009) Cancer Lett , vol.275 , Issue.2 , pp. 170-177
    • Zhang, H.Y.1    Spechler, S.J.2    Souza, R.F.3
  • 6
    • 0033580405 scopus 로고    scopus 로고
    • Symptomatic gastroesophageal reflux as a risk factor for esophageal adenocarcinoma
    • 1:STN:280:DyaK1M7msFeitw%3D%3D 10080844
    • J Lagergren R Bergstrom A Lindgren O Nyren 1999 Symptomatic gastroesophageal reflux as a risk factor for esophageal adenocarcinoma N Engl J Med 340 11 825 831 1:STN:280:DyaK1M7msFeitw%3D%3D 10080844
    • (1999) N Engl J Med , vol.340 , Issue.11 , pp. 825-831
    • Lagergren, J.1    Bergstrom, R.2    Lindgren, A.3    Nyren, O.4
  • 7
    • 0034837434 scopus 로고    scopus 로고
    • Genetic differences between adenocarcinomas arising in Barrett's esophagus and gastric mucosa
    • 1:STN:280:DC%2BD3MvnvFSmsA%3D%3D 11522743
    • W El-Rifai HF Frierson Jr CA Moskaluk, et al. 2001 Genetic differences between adenocarcinomas arising in Barrett's esophagus and gastric mucosa Gastroenterology 121 3 592 598 1:STN:280:DC%2BD3MvnvFSmsA%3D%3D 11522743
    • (2001) Gastroenterology , vol.121 , Issue.3 , pp. 592-598
    • El-Rifai, W.1    Frierson Jr., H.F.2    Moskaluk, C.A.3
  • 8
    • 33644874224 scopus 로고    scopus 로고
    • Hypermethylation and loss of expression of glutathione peroxidase-3 in Barrett's tumorigenesis
    • 1:CAS:528:DC%2BD2MXhtlClurfO 16229808
    • OJ Lee R Schneider-Stock PA McChesney, et al. 2005 Hypermethylation and loss of expression of glutathione peroxidase-3 in Barrett's tumorigenesis Neoplasia 7 9 854 861 1:CAS:528:DC%2BD2MXhtlClurfO 16229808
    • (2005) Neoplasia , vol.7 , Issue.9 , pp. 854-861
    • Lee, O.J.1    Schneider-Stock, R.2    McChesney, P.A.3
  • 9
    • 58249084836 scopus 로고    scopus 로고
    • DNA hypermethylation regulates the expression of members of the mu-class glutathione s-transferases and glutathione peroxidases in Barrett's adenocarcinoma
    • 1:CAS:528:DC%2BD1MXhs1SktL8%3D 18664505
    • DF Peng M Razvi H Chen, et al. 2009 DNA hypermethylation regulates the expression of members of the mu-class glutathione s-transferases and glutathione peroxidases in Barrett's adenocarcinoma Gut 58 1 5 15 1:CAS:528: DC%2BD1MXhs1SktL8%3D 18664505
    • (2009) Gut , vol.58 , Issue.1 , pp. 5-15
    • Peng, D.F.1    Razvi, M.2    Chen, H.3
  • 10
    • 58549106559 scopus 로고    scopus 로고
    • Silencing of mgmt expression by promoter hypermethylation in the metaplasia-dysplasia-carcinoma sequence of Barrett's esophagus
    • 1:CAS:528:DC%2BD1MXhtVeitbc%3D 19027227
    • D Kuester W El-Rifai D Peng, et al. 2009 Silencing of mgmt expression by promoter hypermethylation in the metaplasia-dysplasia-carcinoma sequence of Barrett's esophagus Cancer Lett 275 1 117 126 1:CAS:528:DC%2BD1MXhtVeitbc%3D 19027227
    • (2009) Cancer Lett , vol.275 , Issue.1 , pp. 117-126
    • Kuester, D.1    El-Rifai, W.2    Peng, D.3
  • 11
    • 1642365603 scopus 로고    scopus 로고
    • Biomarkers of esophageal adenocarcinoma and Barrett's esophagus
    • 1:CAS:528:DC%2BD2cXhslektLs%3D 14996709
    • DT McManus A Olaru SJ Meltzer 2004 Biomarkers of esophageal adenocarcinoma and Barrett's esophagus Cancer Res 64 5 1561 1569 1:CAS:528:DC%2BD2cXhslektLs%3D 14996709
    • (2004) Cancer Res , vol.64 , Issue.5 , pp. 1561-1569
    • McManus, D.T.1    Olaru, A.2    Meltzer, S.J.3
  • 12
    • 44849142186 scopus 로고    scopus 로고
    • Three-tiered risk stratification model to predict progression in Barrett's esophagus using epigenetic and clinical features
    • 18382671
    • F Sato Z Jin K Schulmann, et al. 2008 Three-tiered risk stratification model to predict progression in Barrett's esophagus using epigenetic and clinical features PLoS One 3 4 e1890 18382671
    • (2008) PLoS One , vol.3 , Issue.4 , pp. 1890
    • Sato, F.1    Jin, Z.2    Schulmann, K.3
  • 13
    • 0033526355 scopus 로고    scopus 로고
    • Chemo radiotherapy of locally advanced esophageal cancer: Long-term follow-up of a prospective randomized trial (rtog 85-01). Radiation therapy oncology group
    • 1:STN:280:DyaK1M3kvFagtw%3D%3D 10235156
    • JS Cooper MD Guo A Herskovic, et al. 1999 Chemo radiotherapy of locally advanced esophageal cancer: Long-term follow-up of a prospective randomized trial (rtog 85-01). Radiation therapy oncology group JAMA 281 17 1623 1627 1:STN:280:DyaK1M3kvFagtw%3D%3D 10235156
    • (1999) JAMA , vol.281 , Issue.17 , pp. 1623-1627
    • Cooper, J.S.1    Guo, M.D.2    Herskovic, A.3
  • 14
    • 0029737381 scopus 로고    scopus 로고
    • A comparison of multimodal therapy and surgery for esophageal adenocarcinoma
    • 1:STN:280:DyaK283psF2juw%3D%3D 8672151
    • TN Walsh N Noonan D Hollywood A Kelly N Keeling TP Hennessy 1996 A comparison of multimodal therapy and surgery for esophageal adenocarcinoma N Engl J Med 335 7 462 467 1:STN:280:DyaK283psF2juw%3D%3D 8672151
    • (1996) N Engl J Med , vol.335 , Issue.7 , pp. 462-467
    • Walsh, T.N.1    Noonan, N.2    Hollywood, D.3    Kelly, A.4    Keeling, N.5    Hennessy, T.P.6
  • 15
    • 78649322106 scopus 로고    scopus 로고
    • Is radiation therapy needed in the treatment of gastroesophageal junction adenocarcinoma?
    • 19343142
    • JE Tepper 2008 Is radiation therapy needed in the treatment of gastroesophageal junction adenocarcinoma? Gastrointest Cancer Res 2 4 Suppl S2 S5 19343142
    • (2008) Gastrointest Cancer Res , vol.2 , Issue.SUPPL.
    • Tepper, J.E.1
  • 16
    • 0038359143 scopus 로고    scopus 로고
    • A meta-analysis of randomized controlled trials that compared neoadjuvant chemoradiation and surgery to surgery alone for resectable esophageal cancer
    • 12781882
    • JD Urschel H Vasan 2003 A meta-analysis of randomized controlled trials that compared neoadjuvant chemoradiation and surgery to surgery alone for resectable esophageal cancer Am J Surg 185 6 538 543 12781882
    • (2003) Am J Surg , vol.185 , Issue.6 , pp. 538-543
    • Urschel, J.D.1    Vasan, H.2
  • 17
    • 3042584502 scopus 로고    scopus 로고
    • Preoperative chemoradiotherapy for oesophageal cancer: A systematic review and meta-analysis
    • 1:STN:280:DC%2BD2czitVCksA%3D%3D 15194636
    • F Fiorica D Di Bona F Schepis, et al. 2004 Preoperative chemoradiotherapy for oesophageal cancer: a systematic review and meta-analysis Gut 53 7 925 930 1:STN:280:DC%2BD2czitVCksA%3D%3D 15194636
    • (2004) Gut , vol.53 , Issue.7 , pp. 925-930
    • Fiorica, F.1    Di Bona, D.2    Schepis, F.3
  • 18
    • 62649146912 scopus 로고    scopus 로고
    • Preoperative therapy for esophageal cancer
    • 19327572 ix
    • GY Ku DH Ilson 2009 Preoperative therapy for esophageal cancer Gastroenterol Clin North Am 38 1 135 152 19327572 ix
    • (2009) Gastroenterol Clin North Am , vol.38 , Issue.1 , pp. 135-152
    • Ku, G.Y.1    Ilson, D.H.2
  • 19
    • 44349134478 scopus 로고    scopus 로고
    • Treatment results of adenocarcinoma of the gastroesophageal junction
    • 18613391
    • Y Yonemura N Kojima T Kawamura, et al. 2008 Treatment results of adenocarcinoma of the gastroesophageal junction Hepatogastroenterology 55 82-83 475 481 18613391
    • (2008) Hepatogastroenterology , vol.55 , Issue.8283 , pp. 475-481
    • Yonemura, Y.1    Kojima, N.2    Kawamura, T.3
  • 20
    • 0037337363 scopus 로고    scopus 로고
    • Colonic interposition after esophagectomy for cancer
    • 12611579
    • PA Davis S Law J Wong 2003 Colonic interposition after esophagectomy for cancer Arch Surg 138 3 303 308 12611579
    • (2003) Arch Surg , vol.138 , Issue.3 , pp. 303-308
    • Davis, P.A.1    Law, S.2    Wong, J.3
  • 21
    • 36148963600 scopus 로고    scopus 로고
    • Comparing outcomes after transthoracic and transhiatal esophagectomy: A 5-year prospective cohort of 17,395 patients
    • 18035255
    • RC Connors BC Reuben LA Neumayer DA Bull 2007 Comparing outcomes after transthoracic and transhiatal esophagectomy: a 5-year prospective cohort of 17,395 patients J Am Coll Surg 205 6 735 740 18035255
    • (2007) J Am Coll Surg , vol.205 , Issue.6 , pp. 735-740
    • Connors, R.C.1    Reuben, B.C.2    Neumayer, L.A.3    Bull, D.A.4
  • 22
    • 34347353303 scopus 로고    scopus 로고
    • Adenocarcinoma of the gastroesophageal junction: Influence of esophageal resection margin and operative approach on outcome
    • 17592282
    • AP Barbour NP Rizk M Gonen, et al. 2007 Adenocarcinoma of the gastroesophageal junction: influence of esophageal resection margin and operative approach on outcome Ann Surg 246 1 1 8 17592282
    • (2007) Ann Surg , vol.246 , Issue.1 , pp. 1-8
    • Barbour, A.P.1    Rizk, N.P.2    Gonen, M.3
  • 23
    • 0025160290 scopus 로고
    • Surgical therapy of oesophageal carcinoma
    • 1:STN:280:DyaK3czms1ymuw%3D%3D 2203505
    • JM Muller H Erasmi M Stelzner U Zieren H Pichlmaier 1990 Surgical therapy of oesophageal carcinoma Br J Surg 77 8 845 857 1:STN:280:DyaK3czms1ymuw%3D%3D 2203505
    • (1990) Br J Surg , vol.77 , Issue.8 , pp. 845-857
    • Muller, J.M.1    Erasmi, H.2    Stelzner, M.3    Zieren, U.4    Pichlmaier, H.5
  • 24
    • 0037153029 scopus 로고    scopus 로고
    • Extended transthoracic resection compared with limited transhiatal resection for adenocarcinoma of the esophagus
    • 12444180
    • JB Hulscher JW van Sandick AG de Boer, et al. 2002 Extended transthoracic resection compared with limited transhiatal resection for adenocarcinoma of the esophagus N Engl J Med 347 21 1662 1669 12444180
    • (2002) N Engl J Med , vol.347 , Issue.21 , pp. 1662-1669
    • Hulscher, J.B.1    Van Sandick, J.W.2    De Boer, A.G.3
  • 25
    • 0342601968 scopus 로고    scopus 로고
    • Proposal for improved staging criteria for carcinoma of the esophagus and cardia
    • 9332912 discussion 364-365
    • FH Ellis Jr GJ Heatley K Balogh 1997 Proposal for improved staging criteria for carcinoma of the esophagus and cardia Eur J Cardiothorac Surg 12 3 361 364 9332912 discussion 364-365
    • (1997) Eur J Cardiothorac Surg , vol.12 , Issue.3 , pp. 361-364
    • Ellis Jr., F.H.1    Heatley, G.J.2    Balogh, K.3
  • 26
    • 60949104411 scopus 로고    scopus 로고
    • Predictors of major morbidity and mortality after esophagectomy for esophageal cancer: A Society of Thoracic Surgeons general thoracic surgery database risk adjustment model
    • 19258071 discussion 596
    • CD Wright JC Kucharczuk SM O'Brien JD Grab MS Allen 2009 Predictors of major morbidity and mortality after esophagectomy for esophageal cancer: a Society of Thoracic Surgeons general thoracic surgery database risk adjustment model J Thorac Cardiovasc Surg 137 3 587 595 19258071 discussion 596
    • (2009) J Thorac Cardiovasc Surg , vol.137 , Issue.3 , pp. 587-595
    • Wright, C.D.1    Kucharczuk, J.C.2    O'Brien, S.M.3    Grab, J.D.4    Allen, M.S.5
  • 27
    • 43049093717 scopus 로고    scopus 로고
    • Perioperative anesthetic management for esophagectomy
    • 18456214 vi
    • JM Ng 2008 Perioperative anesthetic management for esophagectomy Anesthesiol Clin 26 2 293 304 18456214 vi
    • (2008) Anesthesiol Clin , vol.26 , Issue.2 , pp. 293-304
    • Ng, J.M.1
  • 28
    • 0033967758 scopus 로고    scopus 로고
    • Eliminating the cervical esophagogastric anastomotic leak with a side-to-side stapled anastomosis
    • 1:STN:280:DC%2BD3c7hsFOnug%3D%3D 10649203
    • MB Orringer B Marshall MD Iannettoni 2000 Eliminating the cervical esophagogastric anastomotic leak with a side-to-side stapled anastomosis J Thorac Cardiovasc Surg 119 2 277 288 1:STN:280:DC%2BD3c7hsFOnug%3D%3D 10649203
    • (2000) J Thorac Cardiovasc Surg , vol.119 , Issue.2 , pp. 277-288
    • Orringer, M.B.1    Marshall, B.2    Iannettoni, M.D.3
  • 30
    • 0030881527 scopus 로고    scopus 로고
    • A prospective randomized comparison of transhiatal and transthoracic resection for lower-third esophageal carcinoma
    • 1:STN:280:DyaK2svmsVehtw%3D%3D 9324146
    • KM Chu SY Law M Fok J Wong 1997 A prospective randomized comparison of transhiatal and transthoracic resection for lower-third esophageal carcinoma Am J Surg 174 3 320 324 1:STN:280:DyaK2svmsVehtw%3D%3D 9324146
    • (1997) Am J Surg , vol.174 , Issue.3 , pp. 320-324
    • Chu, K.M.1    Law, S.Y.2    Fok, M.3    Wong, J.4
  • 31
    • 44649130030 scopus 로고    scopus 로고
    • En bloc esophagectomy reduces local recurrence and improves survival compared with transhiatal resection after neoadjuvant therapy for esophageal adenocarcinoma
    • 1:STN:280:DC%2BD1czns1GisQ%3D%3D 18544359
    • C Rizzetto SR DeMeester JA Hagen CG Peyre JC Lipham TR DeMeester 2008 En bloc esophagectomy reduces local recurrence and improves survival compared with transhiatal resection after neoadjuvant therapy for esophageal adenocarcinoma J Thorac Cardiovasc Surg 135 6 1228 1236 1:STN:280:DC%2BD1czns1GisQ%3D%3D 18544359
    • (2008) J Thorac Cardiovasc Surg , vol.135 , Issue.6 , pp. 1228-1236
    • Rizzetto, C.1    Demeester, S.R.2    Hagen, J.A.3    Peyre, C.G.4    Lipham, J.C.5    Demeester, T.R.6
  • 32
    • 26444562421 scopus 로고    scopus 로고
    • Early esophageal cancer: Pattern of lymphatic spread and prognostic factors for long-term survival after surgical resection
    • 16192817 discussion 573-565
    • HJ Stein M Feith BL Bruecher J Naehrig M Sarbia JR Siewert 2005 Early esophageal cancer: pattern of lymphatic spread and prognostic factors for long-term survival after surgical resection Ann Surg 242 4 566 573 16192817 discussion 573-565
    • (2005) Ann Surg , vol.242 , Issue.4 , pp. 566-573
    • Stein, H.J.1    Feith, M.2    Bruecher, B.L.3    Naehrig, J.4    Sarbia, M.5    Siewert, J.R.6
  • 33
    • 0032893289 scopus 로고    scopus 로고
    • Prevalence and location of nodal metastases in distal esophageal adenocarcinoma confined to the wall: Implications for therapy
    • 1:STN:280:DyaK1M7gt1GhsQ%3D%3D 9869753 discussion 23-15
    • JJ Nigro JA Hagen TR DeMeester, et al. 1999 Prevalence and location of nodal metastases in distal esophageal adenocarcinoma confined to the wall: Implications for therapy J Thorac Cardiovasc Surg 117 1 16 23 1:STN:280:DyaK1M7gt1GhsQ%3D%3D 9869753 discussion 23-15
    • (1999) J Thorac Cardiovasc Surg , vol.117 , Issue.1 , pp. 16-23
    • Nigro, J.J.1    Hagen, J.A.2    Demeester, T.R.3
  • 34
    • 0032033714 scopus 로고    scopus 로고
    • Esophageal carcinoma: Depth of tumor invasion is predictive of regional lymph node status
    • 1:STN:280:DyaK1c7os1Cntg%3D%3D 9527214
    • TW Rice G Zuccaro Jr DJ Adelstein LA Rybicki EH Blackstone JR Goldblum 1998 Esophageal carcinoma: depth of tumor invasion is predictive of regional lymph node status Ann Thorac Surg 65 3 787 792 1:STN:280:DyaK1c7os1Cntg%3D%3D 9527214
    • (1998) Ann Thorac Surg , vol.65 , Issue.3 , pp. 787-792
    • Rice, T.W.1    Zuccaro Jr., G.2    Adelstein, D.J.3    Rybicki, L.A.4    Blackstone, E.H.5    Goldblum, J.R.6
  • 35
    • 24044509153 scopus 로고    scopus 로고
    • Surgery alone versus chemoradiotherapy followed by surgery for resectable cancer of the oesophagus: A randomised controlled phase III trial
    • 16129366
    • BH Burmeister BM Smithers V Gebski, et al. 2005 Surgery alone versus chemoradiotherapy followed by surgery for resectable cancer of the oesophagus: a randomised controlled phase III trial Lancet Oncol 6 9 659 668 16129366
    • (2005) Lancet Oncol , vol.6 , Issue.9 , pp. 659-668
    • Burmeister, B.H.1    Smithers, B.M.2    Gebski, V.3
  • 36
    • 33745726677 scopus 로고    scopus 로고
    • Perioperative chemotherapy versus surgery alone for resectable gastroesophageal cancer
    • 1:CAS:528:DC%2BD28Xms1Chsrw%3D 16822992
    • D Cunningham WH Allum SP Stenning, et al. 2006 Perioperative chemotherapy versus surgery alone for resectable gastroesophageal cancer N Engl J Med 355 1 11 20 1:CAS:528:DC%2BD28Xms1Chsrw%3D 16822992
    • (2006) N Engl J Med , vol.355 , Issue.1 , pp. 11-20
    • Cunningham, D.1    Allum, W.H.2    Stenning, S.P.3
  • 37
    • 0037129734 scopus 로고    scopus 로고
    • Surgical resection with or without preoperative chemotherapy in oesophageal cancer: A randomised controlled trial
    • Medical Research Council Oesophageal Cancer Working Group
    • Medical Research Council Oesophageal Cancer Working Group 2002 Surgical resection with or without preoperative chemotherapy in oesophageal cancer: a randomised controlled trial Lancet 359 9319 1727 1733
    • (2002) Lancet , vol.359 , Issue.9319 , pp. 1727-1733
  • 38
    • 0032585510 scopus 로고    scopus 로고
    • Chemotherapy followed by surgery compared with surgery alone for localized esophageal cancer
    • 1:STN:280:DyaK1M%2FnslCjsg%3D%3D 9869669
    • DP Kelsen R Ginsberg TF Pajak, et al. 1998 Chemotherapy followed by surgery compared with surgery alone for localized esophageal cancer N Engl J Med 339 27 1979 1984 1:STN:280:DyaK1M%2FnslCjsg%3D%3D 9869669
    • (1998) N Engl J Med , vol.339 , Issue.27 , pp. 1979-1984
    • Kelsen, D.P.1    Ginsberg, R.2    Pajak, T.F.3
  • 39
    • 0026769381 scopus 로고
    • Combined chemotherapy and radiotherapy compared with radiotherapy alone in patients with cancer of the esophagus
    • 1:STN:280:DyaK383mtFKkuw%3D%3D 1584260
    • A Herskovic K Martz M al-Sarraf, et al. 1992 Combined chemotherapy and radiotherapy compared with radiotherapy alone in patients with cancer of the esophagus N Engl J Med 326 24 1593 1598 1:STN:280:DyaK383mtFKkuw%3D%3D 1584260
    • (1992) N Engl J Med , vol.326 , Issue.24 , pp. 1593-1598
    • Herskovic, A.1    Martz, K.2    Al-Sarraf, M.3
  • 40
    • 0024535574 scopus 로고
    • Randomized clinical trial on the combination of preoperative irradiation and surgery in the treatment of esophageal carcinoma: Report on 206 patients
    • 1:CAS:528:DyaL1MXktV2mt7Y%3D 2646253
    • M Wang XZ Gu WB Yin GJ Huang LJ Wang DW Zhang 1989 Randomized clinical trial on the combination of preoperative irradiation and surgery in the treatment of esophageal carcinoma: report on 206 patients Int J Radiat Oncol Biol Phys 16 2 325 327 1:CAS:528:DyaL1MXktV2mt7Y%3D 2646253
    • (1989) Int J Radiat Oncol Biol Phys , vol.16 , Issue.2 , pp. 325-327
    • Wang, M.1    Gu, X.Z.2    Yin, W.B.3    Huang, G.J.4    Wang, L.J.5    Zhang, D.W.6
  • 41
    • 0031780121 scopus 로고    scopus 로고
    • Preoperative radiotherapy in esophageal carcinoma: A meta-analysis using individual patient data (oesophageal cancer collaborative group)
    • 1:STN:280:DyaK1c3pslKhug%3D%3D 9635705
    • SJ Arnott W Duncan M Gignoux, et al. 1998 Preoperative radiotherapy in esophageal carcinoma: a meta-analysis using individual patient data (oesophageal cancer collaborative group) Int J Radiat Oncol Biol Phys 41 3 579 583 1:STN:280:DyaK1c3pslKhug%3D%3D 9635705
    • (1998) Int J Radiat Oncol Biol Phys , vol.41 , Issue.3 , pp. 579-583
    • Arnott, S.J.1    Duncan, W.2    Gignoux, M.3
  • 42
    • 0027055350 scopus 로고
    • Pre-operative radiotherapy prolongs survival in operable esophageal carcinoma: A randomized, multicenter study of pre-operative radiotherapy and chemotherapy. The second Scandinavian trial in esophageal cancer
    • 1:STN:280:DyaK3s%2FovVyhsg%3D%3D 1455880 discussion 1110
    • K Nygaard S Hagen HS Hansen, et al. 1992 Pre-operative radiotherapy prolongs survival in operable esophageal carcinoma: a randomized, multicenter study of pre-operative radiotherapy and chemotherapy. The second Scandinavian trial in esophageal cancer World J Surg 16 6 1104 1109 1:STN:280: DyaK3s%2FovVyhsg%3D%3D 1455880 discussion 1110
    • (1992) World J Surg , vol.16 , Issue.6 , pp. 1104-1109
    • Nygaard, K.1    Hagen, S.2    Hansen, H.S.3
  • 43
    • 0019866843 scopus 로고
    • Preoperative radiotherapy for carcinoma of the esophagus
    • 1:STN:280:DyaL38%2FktVWgsA%3D%3D 6794167
    • B Launois D Delarue JP Campion M Kerbaol 1981 Preoperative radiotherapy for carcinoma of the esophagus Surg Gynecol Obstet 153 5 690 692 1:STN:280:DyaL38%2FktVWgsA%3D%3D 6794167
    • (1981) Surg Gynecol Obstet , vol.153 , Issue.5 , pp. 690-692
    • Launois, B.1    Delarue, D.2    Campion, J.P.3    Kerbaol, M.4
  • 44
    • 0023222879 scopus 로고
    • The value of preoperative radiotherapy in esophageal cancer: Results of a study of the E.O.R.T.C
    • 1:STN:280:DyaL2szitFChuw%3D%3D 3630187
    • M Gignoux A Roussel B Paillot, et al. 1987 The value of preoperative radiotherapy in esophageal cancer: results of a study of the E.O.R.T.C World J Surg 11 4 426 432 1:STN:280:DyaL2szitFChuw%3D%3D 3630187
    • (1987) World J Surg , vol.11 , Issue.4 , pp. 426-432
    • Gignoux, M.1    Roussel, A.2    Paillot, B.3
  • 45
    • 33646485700 scopus 로고    scopus 로고
    • Systematic overview of preoperative (neoadjuvant) chemoradiotherapy trials in oesophageal cancer: Evidence of a radiation and chemotherapy dose response
    • 1:CAS:528:DC%2BD28Xjs1Wnurc%3D 16545878
    • JI Geh SJ Bond SM Bentzen R Glynne-Jones 2006 Systematic overview of preoperative (neoadjuvant) chemoradiotherapy trials in oesophageal cancer: evidence of a radiation and chemotherapy dose response Radiother Oncol 78 3 236 244 1:CAS:528:DC%2BD28Xjs1Wnurc%3D 16545878
    • (2006) Radiother Oncol , vol.78 , Issue.3 , pp. 236-244
    • Geh, J.I.1    Bond, S.J.2    Bentzen, S.M.3    Glynne-Jones, R.4
  • 46
    • 31544432336 scopus 로고    scopus 로고
    • Induction cisplatin and paclitaxel followed by combination chemoradiotherapy with 5-fluorouracil, cisplatin, and paclitaxel before resection in localized esophageal cancer: A phase II report
    • 16418887
    • LR Henry M Goldberg W Scott, et al. 2006 Induction cisplatin and paclitaxel followed by combination chemoradiotherapy with 5-fluorouracil, cisplatin, and paclitaxel before resection in localized esophageal cancer: a phase II report Ann Surg Oncol 13 2 214 220 16418887
    • (2006) Ann Surg Oncol , vol.13 , Issue.2 , pp. 214-220
    • Henry, L.R.1    Goldberg, M.2    Scott, W.3
  • 47
    • 69849083419 scopus 로고    scopus 로고
    • Multicenter phase II trial of preoperative induction chemotherapy followed by chemoradiation with docetaxel and cisplatin for locally advanced esophageal carcinoma (sakk 75/02)
    • 1:STN:280:DC%2BD1MrnsVCquw%3D%3D 19465425
    • T Ruhstaller L Widmer JC Schuller, et al. 2009 Multicenter phase II trial of preoperative induction chemotherapy followed by chemoradiation with docetaxel and cisplatin for locally advanced esophageal carcinoma (sakk 75/02) Ann Oncol 20 9 1522 1528 1:STN:280:DC%2BD1MrnsVCquw%3D%3D 19465425
    • (2009) Ann Oncol , vol.20 , Issue.9 , pp. 1522-1528
    • Ruhstaller, T.1    Widmer, L.2    Schuller, J.C.3
  • 48
    • 33847156303 scopus 로고    scopus 로고
    • Survival benefits from neoadjuvant chemoradiotherapy or chemotherapy in oesophageal carcinoma: A meta-analysis
    • 1:CAS:528:DC%2BD2sXisVCqs78%3D 17329193
    • V Gebski B Burmeister BM Smithers K Foo J Zalcberg J Simes 2007 Survival benefits from neoadjuvant chemoradiotherapy or chemotherapy in oesophageal carcinoma: a meta-analysis Lancet Oncol 8 3 226 234 1:CAS:528: DC%2BD2sXisVCqs78%3D 17329193
    • (2007) Lancet Oncol , vol.8 , Issue.3 , pp. 226-234
    • Gebski, V.1    Burmeister, B.2    Smithers, B.M.3    Foo, K.4    Zalcberg, J.5    Simes, J.6
  • 49
    • 75449106396 scopus 로고    scopus 로고
    • Neoadjuvant chemoradiotherapy for resectable esophageal carcinoma: A meta-analysis
    • 20014464
    • HL Jin H Zhu TS Ling HJ Zhang RH Shi 2009 Neoadjuvant chemoradiotherapy for resectable esophageal carcinoma: a meta-analysis World J Gastroenterol 15 47 5983 5991 20014464
    • (2009) World J Gastroenterol , vol.15 , Issue.47 , pp. 5983-5991
    • Jin, H.L.1    Zhu, H.2    Ling, T.S.3    Zhang, H.J.4    Shi, R.H.5
  • 51
    • 62349141015 scopus 로고    scopus 로고
    • Survival in lymph node negative adenocarcinoma of the esophagus after R0 resection with and without neoadjuvant therapy: Evidence for downstaging of n status
    • 19476789
    • JM Leers S Ayazi JA Hagen, et al. 2009 Survival in lymph node negative adenocarcinoma of the esophagus after R0 resection with and without neoadjuvant therapy: evidence for downstaging of n status J Am Coll Surg 208 4 553 556 19476789
    • (2009) J Am Coll Surg , vol.208 , Issue.4 , pp. 553-556
    • Leers, J.M.1    Ayazi, S.2    Hagen, J.A.3
  • 52
    • 39749198188 scopus 로고    scopus 로고
    • Persistent association of nailfold capillaroscopy changes and skin involvement over thirty-six months with duration of untreated disease in patients with juvenile dermatomyositis
    • 18240225
    • S Christen-Zaech R Seshadri J Sundberg AS Paller LM Pachman 2008 Persistent association of nailfold capillaroscopy changes and skin involvement over thirty-six months with duration of untreated disease in patients with juvenile dermatomyositis Arthritis Rheum 58 2 571 576 18240225
    • (2008) Arthritis Rheum , vol.58 , Issue.2 , pp. 571-576
    • Christen-Zaech, S.1    Seshadri, R.2    Sundberg, J.3    Paller, A.S.4    Pachman, L.M.5
  • 53
    • 33746961739 scopus 로고    scopus 로고
    • Mechanisms of disease: Oncogene addiction-a rationale for molecular targeting in cancer therapy
    • 1:CAS:528:DC%2BD28Xpt1OktL8%3D 16894390
    • IB Weinstein AK Joe 2006 Mechanisms of disease: oncogene addiction-a rationale for molecular targeting in cancer therapy Nat Clin Pract Oncol 3 8 448 457 1:CAS:528:DC%2BD28Xpt1OktL8%3D 16894390
    • (2006) Nat Clin Pract Oncol , vol.3 , Issue.8 , pp. 448-457
    • Weinstein, I.B.1    Joe, A.K.2
  • 55
    • 52049122139 scopus 로고    scopus 로고
    • Tumor dormancy and oncogene addiction
    • 1:CAS:528:DC%2BD1cXht1Cjsb%2FP 18834407
    • DW Felsher 2008 Tumor dormancy and oncogene addiction APMIS 116 7-8 629 637 1:CAS:528:DC%2BD1cXht1Cjsb%2FP 18834407
    • (2008) APMIS , vol.116 , Issue.78 , pp. 629-637
    • Felsher, D.W.1
  • 56
    • 44849093562 scopus 로고    scopus 로고
    • Oncogene addiction
    • 1:CAS:528:DC%2BD1cXltlSmtrk%3D 18451130 discussion 3080
    • IB Weinstein A Joe 2008 Oncogene addiction Cancer Res 68 9 3077 3080 1:CAS:528:DC%2BD1cXltlSmtrk%3D 18451130 discussion 3080
    • (2008) Cancer Res , vol.68 , Issue.9 , pp. 3077-3080
    • Weinstein, I.B.1    Joe, A.2
  • 57
    • 44849137232 scopus 로고    scopus 로고
    • Oncogene addiction versus oncogene amnesia: Perhaps more than just a bad habit?
    • 1:CAS:528:DC%2BD1cXltlSmtrc%3D 18451131 discussion 3086
    • DW Felsher 2008 Oncogene addiction versus oncogene amnesia: perhaps more than just a bad habit? Cancer Res 68 9 3081 3086 1:CAS:528:DC%2BD1cXltlSmtrc%3D 18451131 discussion 3086
    • (2008) Cancer Res , vol.68 , Issue.9 , pp. 3081-3086
    • Felsher, D.W.1
  • 58
    • 67649354927 scopus 로고    scopus 로고
    • Simultaneous blockade of the epidermal growth factor receptor/mammalian target of rapamycin pathway by epidermal growth factor receptor inhibitors and rapamycin results in reduced cell growth and survival in biliary tract cancer cells
    • 1:CAS:528:DC%2BD1MXntVKgsbY%3D 19509244
    • B Herberger W Berger H Puhalla, et al. 2009 Simultaneous blockade of the epidermal growth factor receptor/mammalian target of rapamycin pathway by epidermal growth factor receptor inhibitors and rapamycin results in reduced cell growth and survival in biliary tract cancer cells Mol Cancer Ther 8 6 1547 1556 1:CAS:528:DC%2BD1MXntVKgsbY%3D 19509244
    • (2009) Mol Cancer Ther , vol.8 , Issue.6 , pp. 1547-1556
    • Herberger, B.1    Berger, W.2    Puhalla, H.3
  • 59
    • 53349142277 scopus 로고    scopus 로고
    • Gains and amplifications of c-myc, EGFR, and 20.Q13 loci in the no dysplasia-dysplasia-adenocarcinoma sequence of Barrett's esophagus
    • 1:CAS:528:DC%2BD1cXnsVKgt7g%3D 18559552
    • AM Rygiel F Milano FJ Ten Kate, et al. 2008 Gains and amplifications of c-myc, EGFR, and 20.Q13 loci in the no dysplasia-dysplasia-adenocarcinoma sequence of Barrett's esophagus Cancer Epidemiol Biomarkers Prev 17 6 1380 1385 1:CAS:528:DC%2BD1cXnsVKgt7g%3D 18559552
    • (2008) Cancer Epidemiol Biomarkers Prev , vol.17 , Issue.6 , pp. 1380-1385
    • Rygiel, A.M.1    Milano, F.2    Ten Kate, F.J.3
  • 60
    • 0032848367 scopus 로고    scopus 로고
    • Concomitant analysis of the epidermal growth factor receptor family in esophageal cancer: Overexpression of epidermal growth factor receptor mRNA but not of c-erbb-2 and c-erbb-3
    • 1:STN:280:DyaK1MvksVWktg%3D%3D 10512940
    • H Friess A Fukuda WH Tang, et al. 1999 Concomitant analysis of the epidermal growth factor receptor family in esophageal cancer: overexpression of epidermal growth factor receptor mRNA but not of c-erbb-2 and c-erbb-3 World J Surg 23 10 1010 1018 1:STN:280:DyaK1MvksVWktg%3D%3D 10512940
    • (1999) World J Surg , vol.23 , Issue.10 , pp. 1010-1018
    • Friess, H.1    Fukuda, A.2    Tang, W.H.3
  • 61
    • 2342437556 scopus 로고    scopus 로고
    • Epidermal growth factor receptor expression correlates with histologic grade in resected esophageal adenocarcinoma
    • 15120370
    • NW Wilkinson JD Black E Roukhadze, et al. 2004 Epidermal growth factor receptor expression correlates with histologic grade in resected esophageal adenocarcinoma J Gastrointest Surg 8 4 448 453 15120370
    • (2004) J Gastrointest Surg , vol.8 , Issue.4 , pp. 448-453
    • Wilkinson, N.W.1    Black, J.D.2    Roukhadze, E.3
  • 62
    • 0033905181 scopus 로고    scopus 로고
    • Molecular biology of esophageal cancer
    • 10967750
    • TA D'Amico DH Harpole Jr 2000 Molecular biology of esophageal cancer Chest Surg Clin N Am 10 3 451 469 10967750
    • (2000) Chest Surg Clin N Am , vol.10 , Issue.3 , pp. 451-469
    • D'Amico, T.A.1    Harpole Jr., D.H.2
  • 63
    • 0033631528 scopus 로고    scopus 로고
    • Malignant progression in Barrett's esophagus: Pathology and molecular biology
    • 1:STN:280:DC%2BD3c7lslKhtw%3D%3D 10693236
    • J Mueller M Werner JR Siewert 2000 Malignant progression in Barrett's esophagus: pathology and molecular biology Recent Results Cancer Res 155 29 41 1:STN:280:DC%2BD3c7lslKhtw%3D%3D 10693236
    • (2000) Recent Results Cancer Res , vol.155 , pp. 29-41
    • Mueller, J.1    Werner, M.2    Siewert, J.R.3
  • 64
    • 34047153280 scopus 로고    scopus 로고
    • Heparin-binding EGF-like growth factor is an early response gene to chemotherapy and contributes to chemotherapy resistance
    • 1:CAS:528:DC%2BD2sXjsFSiuro%3D 17001310
    • F Wang R Liu SW Lee CM Sloss J Couget JC Cusack 2007 Heparin-binding EGF-like growth factor is an early response gene to chemotherapy and contributes to chemotherapy resistance Oncogene 26 14 2006 2016 1:CAS:528: DC%2BD2sXjsFSiuro%3D 17001310
    • (2007) Oncogene , vol.26 , Issue.14 , pp. 2006-2016
    • Wang, F.1    Liu, R.2    Lee, S.W.3    Sloss, C.M.4    Couget, J.5    Cusack, J.C.6
  • 65
    • 33846928248 scopus 로고    scopus 로고
    • Expression of epidermal growth factor receptor in esophageal and esophagogastric junction adenocarcinomas: Association with poor outcome
    • 1:CAS:528:DC%2BD2sXis1Smt74%3D 17211865
    • KL Wang TT Wu IS Choi, et al. 2007 Expression of epidermal growth factor receptor in esophageal and esophagogastric junction adenocarcinomas: association with poor outcome Cancer 109 4 658 667 1:CAS:528:DC%2BD2sXis1Smt74%3D 17211865
    • (2007) Cancer , vol.109 , Issue.4 , pp. 658-667
    • Wang, K.L.1    Wu, T.T.2    Choi, I.S.3
  • 66
    • 0346963103 scopus 로고    scopus 로고
    • Epidermal growth factor receptor, p53 mutation, and pathological response predict survival in patients with locally advanced esophageal cancer treated with preoperative chemoradiotherapy
    • 1:CAS:528:DC%2BD3sXhtVSqurvP 14695149
    • MK Gibson SC Abraham TT Wu, et al. 2003 Epidermal growth factor receptor, p53 mutation, and pathological response predict survival in patients with locally advanced esophageal cancer treated with preoperative chemoradiotherapy Clin Cancer Res 9 17 6461 6468 1:CAS:528:DC%2BD3sXhtVSqurvP 14695149
    • (2003) Clin Cancer Res , vol.9 , Issue.17 , pp. 6461-6468
    • Gibson, M.K.1    Abraham, S.C.2    Wu, T.T.3
  • 67
    • 1542350261 scopus 로고    scopus 로고
    • Cell and molecular biology of the small intestine: New insights into differentiation, growth and repair
    • 1:CAS:528:DC%2BD2cXivFGqs7o%3D 15703624
    • JR Walters 2004 Cell and molecular biology of the small intestine: new insights into differentiation, growth and repair Curr Opin Gastroenterol 20 2 70 76 1:CAS:528:DC%2BD2cXivFGqs7o%3D 15703624
    • (2004) Curr Opin Gastroenterol , vol.20 , Issue.2 , pp. 70-76
    • Walters, J.R.1
  • 68
    • 4744364736 scopus 로고    scopus 로고
    • Expression of the intestinal marker CDX2 in the columnar-lined esophagus with and without intestinal (Barrett's) metaplasia
    • 1:CAS:528:DC%2BD2cXovFOqt78%3D 15167938
    • GM Groisman M Amar A Meir 2004 Expression of the intestinal marker CDX2 in the columnar-lined esophagus with and without intestinal (Barrett's) metaplasia Mod Pathol 17 10 1282 1288 1:CAS:528:DC%2BD2cXovFOqt78%3D 15167938
    • (2004) Mod Pathol , vol.17 , Issue.10 , pp. 1282-1288
    • Groisman, G.M.1    Amar, M.2    Meir, A.3
  • 69
    • 27744567515 scopus 로고    scopus 로고
    • Increased CDX2 and decreased PITX1 homeobox gene expression in Barrett's esophagus and Barrett's-associated adenocarcinoma
    • 16291394
    • RV Lord J Brabender K Wickramasinghe, et al. 2005 Increased CDX2 and decreased PITX1 homeobox gene expression in Barrett's esophagus and Barrett's-associated adenocarcinoma Surgery 138 5 924 931 16291394
    • (2005) Surgery , vol.138 , Issue.5 , pp. 924-931
    • Lord, R.V.1    Brabender, J.2    Wickramasinghe, K.3
  • 70
    • 59149090672 scopus 로고    scopus 로고
    • Bile acid alone, or in combination with acid, induces CDX2 expression through activation of the epidermal growth factor receptor (EGFR)
    • 18854960
    • NE Avissar L Toia Y Hu, et al. 2009 Bile acid alone, or in combination with acid, induces CDX2 expression through activation of the epidermal growth factor receptor (EGFR) J Gastrointest Surg 13 2 212 222 18854960
    • (2009) J Gastrointest Surg , vol.13 , Issue.2 , pp. 212-222
    • Avissar, N.E.1    Toia, L.2    Hu, Y.3
  • 71
    • 33846220461 scopus 로고    scopus 로고
    • Epidermal growth factor receptor kinase domain mutations in esophageal and pancreatic adenocarcinomas
    • EL Kwak J Jankowski SP Thayer, et al. 2006 Epidermal growth factor receptor kinase domain mutations in esophageal and pancreatic adenocarcinomas Clin Cancer Res 12 Pt 1 14 4283 4287
    • (2006) Clin Cancer Res , vol.121 , Issue.14 , pp. 4283-4287
    • Kwak, E.L.1    Jankowski, J.2    Thayer, S.P.3
  • 72
    • 20044379030 scopus 로고    scopus 로고
    • Downregulation of TS, DPD, ERCC1, GST-Pi, EGFR, and HER2 gene expression after neoadjuvant three-modality treatment in patients with esophageal cancer
    • 15737843
    • S Schneider K Uchida J Brabender, et al. 2005 Downregulation of TS, DPD, ERCC1, GST-Pi, EGFR, and HER2 gene expression after neoadjuvant three-modality treatment in patients with esophageal cancer J Am Coll Surg 200 3 336 344 15737843
    • (2005) J Am Coll Surg , vol.200 , Issue.3 , pp. 336-344
    • Schneider, S.1    Uchida, K.2    Brabender, J.3
  • 73
    • 77149128980 scopus 로고    scopus 로고
    • Current opinion on optimal treatment choices in first-line therapy for advanced or metastatic colorectal cancer: Report from the Adelaide Colorectal Tumour Group Meeting; Stockholm, Sweden; September 2008
    • 1:CAS:528:DC%2BC3cXisVehsL0%3D 20100683
    • TJ Price NC Tebbutt CS Karapetis, et al. 2010 Current opinion on optimal treatment choices in first-line therapy for advanced or metastatic colorectal cancer: report from the Adelaide Colorectal Tumour Group Meeting; Stockholm, Sweden; September 2008 Clin Colorectal Cancer 9 1 8 14 1:CAS:528: DC%2BC3cXisVehsL0%3D 20100683
    • (2010) Clin Colorectal Cancer , vol.9 , Issue.1 , pp. 8-14
    • Price, T.J.1    Tebbutt, N.C.2    Karapetis, C.S.3
  • 74
    • 38149088836 scopus 로고    scopus 로고
    • Cetuximab with concurrent chemoradiation for esophagogastric cancer: Assessment of toxicity
    • 1:CAS:528:DC%2BD1cXosVGnug%3D%3D 17980508
    • H Safran M Suntharalingam T Dipetrillo, et al. 2008 Cetuximab with concurrent chemoradiation for esophagogastric cancer: assessment of toxicity Int J Radiat Oncol Biol Phys 70 2 391 395 1:CAS:528:DC%2BD1cXosVGnug%3D%3D 17980508
    • (2008) Int J Radiat Oncol Biol Phys , vol.70 , Issue.2 , pp. 391-395
    • Safran, H.1    Suntharalingam, M.2    Dipetrillo, T.3
  • 75
    • 33847663871 scopus 로고    scopus 로고
    • Phase II study of cetuximab in combination with FOLFIRI in patients with untreated advanced gastric or gastroesophageal junction adenocarcinoma (FOLCETUX study)
    • 1:STN:280:DC%2BD2s7hsVKjsA%3D%3D 17164226
    • C Pinto F Di Fabio S Siena, et al. 2007 Phase II study of cetuximab in combination with FOLFIRI in patients with untreated advanced gastric or gastroesophageal junction adenocarcinoma (FOLCETUX study) Ann Oncol 18 3 510 517 1:STN:280:DC%2BD2s7hsVKjsA%3D%3D 17164226
    • (2007) Ann Oncol , vol.18 , Issue.3 , pp. 510-517
    • Pinto, C.1    Di Fabio, F.2    Siena, S.3
  • 76
    • 45549103190 scopus 로고    scopus 로고
    • Epidermal growth factor receptor-directed therapy in esophageal cancer
    • 1:CAS:528:DC%2BD1cXnsVCls70%3D 18477853
    • AU Pande RV Iyer A Rani, et al. 2007 Epidermal growth factor receptor-directed therapy in esophageal cancer Oncology 73 5-6 281 289 1:CAS:528:DC%2BD1cXnsVCls70%3D 18477853
    • (2007) Oncology , vol.73 , Issue.56 , pp. 281-289
    • Pande, A.U.1    Iyer, R.V.2    Rani, A.3
  • 77
    • 33644860817 scopus 로고    scopus 로고
    • Targeting the epidermal growth factor receptor by erlotinib (Tarceva) for the treatment of esophageal cancer
    • 1:CAS:528:DC%2BD28XislKlsb4%3D 16217753
    • AP Sutter M Hopfner A Huether K Maaser H Scherubl 2006 Targeting the epidermal growth factor receptor by erlotinib (Tarceva) for the treatment of esophageal cancer Int J Cancer 118 7 1814 1822 1:CAS:528:DC%2BD28XislKlsb4%3D 16217753
    • (2006) Int J Cancer , vol.118 , Issue.7 , pp. 1814-1822
    • Sutter, A.P.1    Hopfner, M.2    Huether, A.3    Maaser, K.4    Scherubl, H.5
  • 78
    • 33646089413 scopus 로고    scopus 로고
    • Epidermal growth factor receptor tyrosine kinase inhibitor, erlotinib, and concurrent 5-fluorouracil, cisplatin and radiotherapy for patients with esophageal cancer: A phase i study
    • 1:CAS:528:DC%2BD2MXht1Glt7zP 16317296
    • MC Dobelbower SM Russo KP Raisch, et al. 2006 Epidermal growth factor receptor tyrosine kinase inhibitor, erlotinib, and concurrent 5-fluorouracil, cisplatin and radiotherapy for patients with esophageal cancer: a phase I study Anticancer Drugs 17 1 95 102 1:CAS:528:DC%2BD2MXht1Glt7zP 16317296
    • (2006) Anticancer Drugs , vol.17 , Issue.1 , pp. 95-102
    • Dobelbower, M.C.1    Russo, S.M.2    Raisch, K.P.3
  • 79
    • 33750618860 scopus 로고    scopus 로고
    • Phase II trial of erlotinib in gastroesophageal junction and gastric adenocarcinomas: SWOG 0127
    • 1:CAS:528:DC%2BD28Xht1eiu73L 17050876
    • T Dragovich S McCoy CM Fenoglio-Preiser, et al. 2006 Phase II trial of erlotinib in gastroesophageal junction and gastric adenocarcinomas: SWOG 0127 J Clin Oncol 24 30 4922 4927 1:CAS:528:DC%2BD28Xht1eiu73L 17050876
    • (2006) J Clin Oncol , vol.24 , Issue.30 , pp. 4922-4927
    • Dragovich, T.1    McCoy, S.2    Fenoglio-Preiser, C.M.3
  • 80
    • 55449114575 scopus 로고    scopus 로고
    • Pilot study of gefitinib, oxaliplatin, and radiotherapy for esophageal adenocarcinoma: Tissue effect predicts clinical response
    • 1:CAS:528:DC%2BD1cXpvFKnsbY%3D 18845990
    • M Javle A Pande R Iyer, et al. 2008 Pilot study of gefitinib, oxaliplatin, and radiotherapy for esophageal adenocarcinoma: tissue effect predicts clinical response Am J Clin Oncol 31 4 329 334 1:CAS:528: DC%2BD1cXpvFKnsbY%3D 18845990
    • (2008) Am J Clin Oncol , vol.31 , Issue.4 , pp. 329-334
    • Javle, M.1    Pande, A.2    Iyer, R.3
  • 81
    • 35348826772 scopus 로고    scopus 로고
    • A phase II study of gefitinib monotherapy in advanced esophageal adenocarcinoma: Evidence of gene expression, cellular, and clinical response
    • 1:CAS:528:DC%2BD2sXhtFSntLvP 17908981
    • DR Ferry M Anderson K Beddard, et al. 2007 A phase II study of gefitinib monotherapy in advanced esophageal adenocarcinoma: evidence of gene expression, cellular, and clinical response Clin Cancer Res 13 19 5869 5875 1:CAS:528:DC%2BD2sXhtFSntLvP 17908981
    • (2007) Clin Cancer Res , vol.13 , Issue.19 , pp. 5869-5875
    • Ferry, D.R.1    Anderson, M.2    Beddard, K.3
  • 82
    • 34247245135 scopus 로고    scopus 로고
    • Oncogenic K-ras signals through epidermal growth factor receptor and wild-type H-ras to promote radiation survival in pancreatic and colorectal carcinoma cells
    • 1:CAS:528:DC%2BD2sXkvVWgsrw%3D 17460778
    • KA Cengel KR Voong S Chandrasekaran, et al. 2007 Oncogenic K-ras signals through epidermal growth factor receptor and wild-type H-ras to promote radiation survival in pancreatic and colorectal carcinoma cells Neoplasia 9 4 341 348 1:CAS:528:DC%2BD2sXkvVWgsrw%3D 17460778
    • (2007) Neoplasia , vol.9 , Issue.4 , pp. 341-348
    • Cengel, K.A.1    Voong, K.R.2    Chandrasekaran, S.3
  • 83
    • 33846702126 scopus 로고    scopus 로고
    • Activation of downstream epidermal growth factor receptor (EGFR) signaling provides gefitinib-resistance in cells carrying EGFR mutation
    • 1:CAS:528:DC%2BD2sXis1amtLw%3D 17270025
    • A Uchida S Hirano H Kitao, et al. 2007 Activation of downstream epidermal growth factor receptor (EGFR) signaling provides gefitinib-resistance in cells carrying EGFR mutation Cancer Sci 98 3 357 363 1:CAS:528:DC%2BD2sXis1amtLw%3D 17270025
    • (2007) Cancer Sci , vol.98 , Issue.3 , pp. 357-363
    • Uchida, A.1    Hirano, S.2    Kitao, H.3
  • 84
    • 0034230732 scopus 로고    scopus 로고
    • K-ras codon 12 mutations in Barrett's oesophagus and adenocarcinomas of the oesophagus and oesophagogastric junction
    • 1:CAS:528:DC%2BD3cXlvFWntb4%3D 10937677
    • RV Lord R O'Grady C Sheehan AF Field RL Ward 2000 K-ras codon 12 mutations in Barrett's oesophagus and adenocarcinomas of the oesophagus and oesophagogastric junction J Gastroenterol Hepatol 15 7 730 736 1:CAS:528:DC%2BD3cXlvFWntb4%3D 10937677
    • (2000) J Gastroenterol Hepatol , vol.15 , Issue.7 , pp. 730-736
    • Lord, R.V.1    O'Grady, R.2    Sheehan, C.3    Field, A.F.4    Ward, R.L.5
  • 85
    • 36249001678 scopus 로고    scopus 로고
    • Bile acids induce overexpression of homeobox gene CDX-2 and vascular endothelial growth factor (VEGF) in human Barrett's esophageal mucosa and adenocarcinoma cell line
    • 1:CAS:528:DC%2BD2sXht1ynu7vK 17852856
    • G Burnat T Rau E Elshimi EG Hahn PC Konturek 2007 Bile acids induce overexpression of homeobox gene CDX-2 and vascular endothelial growth factor (VEGF) in human Barrett's esophageal mucosa and adenocarcinoma cell line Scand J Gastroenterol 42 12 1460 1465 1:CAS:528:DC%2BD2sXht1ynu7vK 17852856
    • (2007) Scand J Gastroenterol , vol.42 , Issue.12 , pp. 1460-1465
    • Burnat, G.1    Rau, T.2    Elshimi, E.3    Hahn, E.G.4    Konturek, P.C.5
  • 86
    • 33646590940 scopus 로고    scopus 로고
    • Molecular determinants in targeted therapy for esophageal adenocarcinoma
    • 1:CAS:528:DC%2BD28Xlt1SlsLo%3D 16702519 discussion 481-472
    • D Vallbohmer JH Peters H Kuramochi, et al. 2006 Molecular determinants in targeted therapy for esophageal adenocarcinoma Arch Surg 141 5 476 481 1:CAS:528:DC%2BD28Xlt1SlsLo%3D 16702519 discussion 481-472
    • (2006) Arch Surg , vol.141 , Issue.5 , pp. 476-481
    • Vallbohmer, D.1    Peters, J.H.2    Kuramochi, H.3
  • 87
    • 57349134381 scopus 로고    scopus 로고
    • Genetic polymorphisms of VEGF, interactions with cigarette smoking exposure and esophageal adenocarcinoma risk
    • 1:CAS:528:DC%2BD1cXhsVOgsLfN 18780893
    • R Zhai G Liu K Asomaning, et al. 2008 Genetic polymorphisms of VEGF, interactions with cigarette smoking exposure and esophageal adenocarcinoma risk Carcinogenesis 29 12 2330 2334 1:CAS:528:DC%2BD1cXhsVOgsLfN 18780893
    • (2008) Carcinogenesis , vol.29 , Issue.12 , pp. 2330-2334
    • Zhai, R.1    Liu, G.2    Asomaning, K.3
  • 88
    • 33644638219 scopus 로고    scopus 로고
    • Expression of carbonic anhydrase IX (CA IX), a hypoxia-related protein, rather than vascular-endothelial growth factor (VEGF), a pro-angiogenic factor, correlates with an extremely poor prognosis in esophageal and gastric adenocarcinomas
    • 16495697
    • A Driessen W Landuyt S Pastorekova, et al. 2006 Expression of carbonic anhydrase IX (CA IX), a hypoxia-related protein, rather than vascular-endothelial growth factor (VEGF), a pro-angiogenic factor, correlates with an extremely poor prognosis in esophageal and gastric adenocarcinomas Ann Surg 243 3 334 340 16495697
    • (2006) Ann Surg , vol.243 , Issue.3 , pp. 334-340
    • Driessen, A.1    Landuyt, W.2    Pastorekova, S.3
  • 89
    • 33846629672 scopus 로고    scopus 로고
    • Multicenter phase II study of irinotecan, cisplatin, and bevacizumab in patients with metastatic gastric or gastroesophageal junction adenocarcinoma
    • 1:CAS:528:DC%2BD28XhtlemurbM 17114652
    • MA Shah RK Ramanathan DH Ilson, et al. 2006 Multicenter phase II study of irinotecan, cisplatin, and bevacizumab in patients with metastatic gastric or gastroesophageal junction adenocarcinoma J Clin Oncol 24 33 5201 5206 1:CAS:528:DC%2BD28XhtlemurbM 17114652
    • (2006) J Clin Oncol , vol.24 , Issue.33 , pp. 5201-5206
    • Shah, M.A.1    Ramanathan, R.K.2    Ilson, D.H.3
  • 90
    • 3843150503 scopus 로고    scopus 로고
    • Vascular endothelial growth factor in esophageal cancer
    • 1:CAS:528:DC%2BD2cXns1Ghtrk%3D 15282704
    • A Kleespies M Guba KW Jauch CJ Bruns 2004 Vascular endothelial growth factor in esophageal cancer J Surg Oncol 87 2 95 104 1:CAS:528: DC%2BD2cXns1Ghtrk%3D 15282704
    • (2004) J Surg Oncol , vol.87 , Issue.2 , pp. 95-104
    • Kleespies, A.1    Guba, M.2    Jauch, K.W.3    Bruns, C.J.4
  • 91
    • 33746863318 scopus 로고    scopus 로고
    • Molecular dissection of 17q12 amplicon in upper gastrointestinal adenocarcinomas
    • 1:CAS:528:DC%2BD28XmvFGku70%3D 16849520
    • N Maqani A Belkhiri C Moskaluk S Knuutila AA Dar W El-Rifai 2006 Molecular dissection of 17q12 amplicon in upper gastrointestinal adenocarcinomas Mol Cancer Res 4 7 449 455 1:CAS:528:DC%2BD28XmvFGku70%3D 16849520
    • (2006) Mol Cancer Res , vol.4 , Issue.7 , pp. 449-455
    • Maqani, N.1    Belkhiri, A.2    Moskaluk, C.3    Knuutila, S.4    Dar, A.A.5    El-Rifai, W.6
  • 92
    • 19644373932 scopus 로고    scopus 로고
    • ERBB2 amplifications in esophageal adenocarcinoma
    • 15511476
    • PS Dahlberg BA Jacobson G Dahal, et al. 2004 ERBB2 amplifications in esophageal adenocarcinoma Ann Thorac Surg 78 5 1790 1800 15511476
    • (2004) Ann Thorac Surg , vol.78 , Issue.5 , pp. 1790-1800
    • Dahlberg, P.S.1    Jacobson, B.A.2    Dahal, G.3
  • 93
    • 7244236377 scopus 로고    scopus 로고
    • Coamplification and coexpression of GRB7 and ERBB2 is found in high grade intraepithelial neoplasia and in invasive Barrett's carcinoma
    • 1:CAS:528:DC%2BD2cXpslKru7Y%3D 15386389
    • A Walch K Specht H Braselmann, et al. 2004 Coamplification and coexpression of GRB7 and ERBB2 is found in high grade intraepithelial neoplasia and in invasive Barrett's carcinoma Int J Cancer 112 5 747 753 1:CAS:528:DC%2BD2cXpslKru7Y%3D 15386389
    • (2004) Int J Cancer , vol.112 , Issue.5 , pp. 747-753
    • Walch, A.1    Specht, K.2    Braselmann, H.3
  • 94
    • 0027294912 scopus 로고
    • Amplification and over-expression of the EGFR and erbB-2 genes in human esophageal adenocarcinomas
    • 1:STN:280:DyaK3s3lt1CqtA%3D%3D 8098013
    • M al-Kasspooles JH Moore MB Orringer DG Beer 1993 Amplification and over-expression of the EGFR and erbB-2 genes in human esophageal adenocarcinomas Int J Cancer 54 2 213 219 1:STN:280:DyaK3s3lt1CqtA%3D%3D 8098013
    • (1993) Int J Cancer , vol.54 , Issue.2 , pp. 213-219
    • Al-Kasspooles, M.1    Moore, J.H.2    Orringer, M.B.3    Beer, D.G.4
  • 95
    • 33845689934 scopus 로고    scopus 로고
    • Frequent homogeneous HER-2 amplification in primary and metastatic adenocarcinoma of the esophagus
    • 1:CAS:528:DC%2BD28XhtlaktrnL 17143264
    • U Reichelt P Duesedau M Tsourlakis, et al. 2007 Frequent homogeneous HER-2 amplification in primary and metastatic adenocarcinoma of the esophagus Mod Pathol 20 1 120 129 1:CAS:528:DC%2BD28XhtlaktrnL 17143264
    • (2007) Mod Pathol , vol.20 , Issue.1 , pp. 120-129
    • Reichelt, U.1    Duesedau, P.2    Tsourlakis, M.3
  • 96
    • 33748299461 scopus 로고    scopus 로고
    • Her-2/neu in Barrett esophagus: A comparative study between histology, immunohistochemistry, and fluorescence in situ hybridization
    • 1:CAS:528:DC%2BD28XhtVWnt7zP 16932066
    • E Rossi V Villanacci G Bassotti, et al. 2006 Her-2/neu in Barrett esophagus: a comparative study between histology, immunohistochemistry, and fluorescence in situ hybridization Diagn Mol Pathol 15 3 125 130 1:CAS:528:DC%2BD28XhtVWnt7zP 16932066
    • (2006) Diagn Mol Pathol , vol.15 , Issue.3 , pp. 125-130
    • Rossi, E.1    Villanacci, V.2    Bassotti, G.3
  • 97
    • 0033963379 scopus 로고    scopus 로고
    • HER-2/neu gene amplification by fish predicts poor survival in Barrett's esophagus-associated adenocarcinoma
    • 1:CAS:528:DC%2BD3cXptVegtA%3D%3D 10665910
    • TP Brien RD Odze CE Sheehan BJ McKenna JS Ross 2000 HER-2/neu gene amplification by fish predicts poor survival in Barrett's esophagus-associated adenocarcinoma Hum Pathol 31 1 35 39 1:CAS:528:DC%2BD3cXptVegtA%3D%3D 10665910
    • (2000) Hum Pathol , vol.31 , Issue.1 , pp. 35-39
    • Brien, T.P.1    Odze, R.D.2    Sheehan, C.E.3    McKenna, B.J.4    Ross, J.S.5
  • 98
    • 0037099616 scopus 로고    scopus 로고
    • Gastric cancers overexpress DARPP-32 and a novel isoform, t-DARPP
    • 1:CAS:528:DC%2BD38XlsV2lsb0%3D 12124342
    • W El-Rifai MF Smith Jr G Li, et al. 2002 Gastric cancers overexpress DARPP-32 and a novel isoform, t-DARPP Cancer Res 62 14 4061 4064 1:CAS:528:DC%2BD38XlsV2lsb0%3D 12124342
    • (2002) Cancer Res , vol.62 , Issue.14 , pp. 4061-4064
    • El-Rifai, W.1    Smith Jr., M.F.2    Li, G.3
  • 99
    • 23044503458 scopus 로고    scopus 로고
    • DARPP-32: A novel antiapoptotic gene in upper gastrointestinal carcinomas
    • 1:CAS:528:DC%2BD2MXmvFSltrg%3D 16061638
    • A Belkhiri A Zaika N Pidkovka S Knuutila C Moskaluk W El-Rifai 2005 DARPP-32: a novel antiapoptotic gene in upper gastrointestinal carcinomas Cancer Res 65 15 6583 6592 1:CAS:528:DC%2BD2MXmvFSltrg%3D 16061638
    • (2005) Cancer Res , vol.65 , Issue.15 , pp. 6583-6592
    • Belkhiri, A.1    Zaika, A.2    Pidkovka, N.3    Knuutila, S.4    Moskaluk, C.5    El-Rifai, W.6
  • 100
    • 51649096911 scopus 로고    scopus 로고
    • Expression of t-DARPP mediates trastuzumab resistance in breast cancer cells
    • 1:CAS:528:DC%2BD1cXosFGitbw%3D 18579663
    • A Belkhiri AA Dar DF Peng, et al. 2008 Expression of t-DARPP mediates trastuzumab resistance in breast cancer cells Clin Cancer Res 14 14 4564 4571 1:CAS:528:DC%2BD1cXosFGitbw%3D 18579663
    • (2008) Clin Cancer Res , vol.14 , Issue.14 , pp. 4564-4571
    • Belkhiri, A.1    Dar, A.A.2    Peng, D.F.3
  • 101
    • 74849117382 scopus 로고    scopus 로고
    • Both t-DARPP and DARPP-32 can cause resistance to trastuzumab in breast cancer cells and are frequently expressed in primary breast cancers
    • 19301121
    • S Hamel A Bouchard C Ferrario, et al. 2009 Both t-DARPP and DARPP-32 can cause resistance to trastuzumab in breast cancer cells and are frequently expressed in primary breast cancers Breast Cancer Res Treat 120 47 57 19301121
    • (2009) Breast Cancer Res Treat , vol.120 , pp. 47-57
    • Hamel, S.1    Bouchard, A.2    Ferrario, C.3
  • 102
    • 11144352181 scopus 로고    scopus 로고
    • Monoclonal antibody to HER-2/neu receptor enhances radiosensitivity of esophageal cancer cell lines expressing HER-2/neu oncoprotein
    • 1:CAS:528:DC%2BD2MXjsVCq 15629613
    • S Sato Y Kajiyama M Sugano, et al. 2005 Monoclonal antibody to HER-2/neu receptor enhances radiosensitivity of esophageal cancer cell lines expressing HER-2/neu oncoprotein Int J Radiat Oncol Biol Phys 61 1 203 211 1:CAS:528:DC%2BD2MXjsVCq 15629613
    • (2005) Int J Radiat Oncol Biol Phys , vol.61 , Issue.1 , pp. 203-211
    • Sato, S.1    Kajiyama, Y.2    Sugano, M.3
  • 103
    • 33846227021 scopus 로고    scopus 로고
    • Phase I/II study of trastuzumab, paclitaxel, cisplatin and radiation for locally advanced, HER2 overexpressing, esophageal adenocarcinoma
    • 1:CAS:528:DC%2BD2sXntlentA%3D%3D 17097832
    • H Safran T Dipetrillo P Akerman, et al. 2007 Phase I/II study of trastuzumab, paclitaxel, cisplatin and radiation for locally advanced, HER2 overexpressing, esophageal adenocarcinoma Int J Radiat Oncol Biol Phys 67 2 405 409 1:CAS:528:DC%2BD2sXntlentA%3D%3D 17097832
    • (2007) Int J Radiat Oncol Biol Phys , vol.67 , Issue.2 , pp. 405-409
    • Safran, H.1    Dipetrillo, T.2    Akerman, P.3
  • 104
    • 70350204423 scopus 로고    scopus 로고
    • Efficacy results from the ToGA trial: A phase III study of trastuzumab added to standard chemotherapy (CT) in first-line human epidermal growth factor receptor 2 (HER2)-positive advanced gastric cancer (GC) (abstract from 2009 ASCO Annual Meeting)
    • abstract no. LBA4507
    • Van Cutsem E, Kang Y-K, Chung HC, et al. Efficacy results from the ToGA trial: A phase III study of trastuzumab added to standard chemotherapy (CT) in first-line human epidermal growth factor receptor 2 (HER2)-positive advanced gastric cancer (GC) (abstract from 2009 ASCO Annual Meeting). J Clin Oncol. 2009;27(18S), abstract no. LBA4507.
    • (2009) J Clin Oncol. , vol.27 , Issue.18
    • Van Cutsem, E.1    Kang, Y.-K.2    Chung, H.C.3
  • 105
    • 19944427370 scopus 로고    scopus 로고
    • Trastuzumab, paclitaxel, cisplatin, and radiation for adenocarcinoma of the esophagus: A phase i study
    • 1:CAS:528:DC%2BD2cXosFShsr4%3D 15581047
    • H Safran T DiPetrillo A Nadeem, et al. 2004 Trastuzumab, paclitaxel, cisplatin, and radiation for adenocarcinoma of the esophagus: a phase I study Cancer Invest 22 5 670 677 1:CAS:528:DC%2BD2cXosFShsr4%3D 15581047
    • (2004) Cancer Invest , vol.22 , Issue.5 , pp. 670-677
    • Safran, H.1    Dipetrillo, T.2    Nadeem, A.3
  • 106
    • 51649095569 scopus 로고    scopus 로고
    • The Aurora kinase family in cell division and cancer
    • 1:CAS:528:DC%2BD1cXhtFCktrfE 18662747
    • G Vader SM Lens 2008 The Aurora kinase family in cell division and cancer Biochim Biophys Acta 1786 1 60 72 1:CAS:528:DC%2BD1cXhtFCktrfE 18662747
    • (2008) Biochim Biophys Acta , vol.1786 , Issue.1 , pp. 60-72
    • Vader, G.1    Lens, S.M.2
  • 107
    • 23744503085 scopus 로고    scopus 로고
    • Aurora kinases: Shining lights on the therapeutic horizon?
    • 1:CAS:528:DC%2BD2MXmsFKqsrc%3D 16049526
    • PD Andrews 2005 Aurora kinases: shining lights on the therapeutic horizon? Oncogene 24 32 5005 5015 1:CAS:528:DC%2BD2MXmsFKqsrc%3D 16049526
    • (2005) Oncogene , vol.24 , Issue.32 , pp. 5005-5015
    • Andrews, P.D.1
  • 108
    • 0037017398 scopus 로고    scopus 로고
    • Drosophila Aurora A kinase is required to localize D-TACC to centrosomes and to regulate astral microtubules
    • 1:CAS:528:DC%2BD38XhtVOqt7g%3D 11827981
    • R Giet D McLean S Descamps, et al. 2002 Drosophila Aurora A kinase is required to localize D-TACC to centrosomes and to regulate astral microtubules J Cell Biol 156 3 437 451 1:CAS:528:DC%2BD38XhtVOqt7g%3D 11827981
    • (2002) J Cell Biol , vol.156 , Issue.3 , pp. 437-451
    • Giet, R.1    McLean, D.2    Descamps, S.3
  • 109
    • 33845743957 scopus 로고    scopus 로고
    • Aurora kinases: New targets for cancer therapy
    • 1:CAS:528:DC%2BD28Xht1Kns7rK 17145803
    • RD Carvajal A Tse GK Schwartz 2006 Aurora kinases: new targets for cancer therapy Clin Cancer Res 12 23 6869 6875 1:CAS:528:DC%2BD28Xht1Kns7rK 17145803
    • (2006) Clin Cancer Res , vol.12 , Issue.23 , pp. 6869-6875
    • Carvajal, R.D.1    Tse, A.2    Schwartz, G.K.3
  • 110
    • 0031714080 scopus 로고    scopus 로고
    • Tumour amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation
    • 1:CAS:528:DyaK1cXms1eis78%3D 9771714
    • H Zhou J Kuang L Zhong, et al. 1998 Tumour amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation Nat Genet 20 2 189 193 1:CAS:528:DyaK1cXms1eis78%3D 9771714
    • (1998) Nat Genet , vol.20 , Issue.2 , pp. 189-193
    • Zhou, H.1    Kuang, J.2    Zhong, L.3
  • 111
    • 42149088289 scopus 로고    scopus 로고
    • Frequent overexpression of Aurora Kinase A in upper gastrointestinal adenocarcinomas correlates with potent antiapoptotic functions
    • 1:CAS:528:DC%2BD1cXls1Gkt74%3D 18311783
    • AA Dar A Zaika MB Piazuelo, et al. 2008 Frequent overexpression of Aurora Kinase A in upper gastrointestinal adenocarcinomas correlates with potent antiapoptotic functions Cancer 112 8 1688 1698 1:CAS:528:DC%2BD1cXls1Gkt74%3D 18311783
    • (2008) Cancer , vol.112 , Issue.8 , pp. 1688-1698
    • Dar, A.A.1    Zaika, A.2    Piazuelo, M.B.3
  • 112
    • 30544438805 scopus 로고    scopus 로고
    • Polymorphisms of the AURKA (STK15/Aurora kinase) gene and breast cancer risk (United States)
    • 16411056
    • DG Cox SE Hankinson DJ Hunter 2006 Polymorphisms of the AURKA (STK15/Aurora kinase) gene and breast cancer risk (United States) Cancer Causes Control 17 1 81 83 16411056
    • (2006) Cancer Causes Control , vol.17 , Issue.1 , pp. 81-83
    • Cox, D.G.1    Hankinson, S.E.2    Hunter, D.J.3
  • 113
    • 34249791474 scopus 로고    scopus 로고
    • Aurora-A and p16 polymorphisms contribute to an earlier age at diagnosis of pancreatic cancer in Caucasians
    • 1:CAS:528:DC%2BD2sXlt1KrtbY%3D 17505013
    • J Chen D Li C Wei, et al. 2007 Aurora-A and p16 polymorphisms contribute to an earlier age at diagnosis of pancreatic cancer in Caucasians Clin Cancer Res 13 10 3100 3104 1:CAS:528:DC%2BD2sXlt1KrtbY%3D 17505013
    • (2007) Clin Cancer Res , vol.13 , Issue.10 , pp. 3100-3104
    • Chen, J.1    Li, D.2    Wei, C.3
  • 114
    • 55349124289 scopus 로고    scopus 로고
    • Aurora kinase A inhibition leads to p73-dependent apoptosis in p53- deficient cancer cells
    • 1:CAS:528:DC%2BD1cXhtlSkurzE 18974145
    • AA Dar A Belkhiri J Ecsedy A Zaika W El-Rifai 2008 Aurora kinase A inhibition leads to p73-dependent apoptosis in p53- deficient cancer cells Cancer Res 68 21 8998 9004 1:CAS:528:DC%2BD1cXhtlSkurzE 18974145
    • (2008) Cancer Res , vol.68 , Issue.21 , pp. 8998-9004
    • Dar, A.A.1    Belkhiri, A.2    Ecsedy, J.3    Zaika, A.4    El-Rifai, W.5
  • 115
    • 60149085428 scopus 로고    scopus 로고
    • The Aurora kinase A regulates GSK-3β in gastric cancer cells
    • 19060929
    • AA Dar A Belkhiri W El-Rifai 2008 The Aurora kinase A regulates GSK-3β in gastric cancer cells Oncogene 28 866 875 19060929
    • (2008) Oncogene , vol.28 , pp. 866-875
    • Dar, A.A.1    Belkhiri, A.2    El-Rifai, W.3
  • 116
    • 53049109358 scopus 로고    scopus 로고
    • Targeting Aurora kinase with MK-0457 inhibits ovarian cancer growth
    • 1:CAS:528:DC%2BD1cXhtVKmsbvF 18765535
    • YG Lin A Immaneni WM Merritt, et al. 2008 Targeting Aurora kinase with MK-0457 inhibits ovarian cancer growth Clin Cancer Res 14 17 5437 5446 1:CAS:528:DC%2BD1cXhtVKmsbvF 18765535
    • (2008) Clin Cancer Res , vol.14 , Issue.17 , pp. 5437-5446
    • Lin, Y.G.1    Immaneni, A.2    Merritt, W.M.3
  • 117
    • 59349096086 scopus 로고    scopus 로고
    • The Aurora kinase inhibitor VE-465 has anticancer effects in pre-clinical studies of human hepatocellular carcinoma
    • 1:CAS:528:DC%2BD1MXhs1ektrk%3D 19155085
    • ZZ Lin HC Hsu CH Hsu, et al. 2009 The Aurora kinase inhibitor VE-465 has anticancer effects in pre-clinical studies of human hepatocellular carcinoma J Hepatol 50 3 518 527 1:CAS:528:DC%2BD1MXhs1ektrk%3D 19155085
    • (2009) J Hepatol , vol.50 , Issue.3 , pp. 518-527
    • Lin, Z.Z.1    Hsu, H.C.2    Hsu, C.H.3
  • 119
    • 67649588612 scopus 로고    scopus 로고
    • Aurora kinase inhibitors in preclinical and clinical testing
    • 1:CAS:528:DC%2BD1MXjvVWnsLo%3D 19335272
    • CH Cheung MS Coumar HP Hsieh JY Chang 2009 Aurora kinase inhibitors in preclinical and clinical testing Expert Opin Investig Drugs 18 4 379 398 1:CAS:528:DC%2BD1MXjvVWnsLo%3D 19335272
    • (2009) Expert Opin Investig Drugs , vol.18 , Issue.4 , pp. 379-398
    • Cheung, C.H.1    Coumar, M.S.2    Hsieh, H.P.3    Chang, J.Y.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.