-
2
-
-
3042656398
-
Stomach cancer
-
Stewart BW, Kleihues P, eds. Lyon: IARC Press
-
Ohgaki H, Matsukura N. Stomach cancer. In: Stewart BW, Kleihues P, eds. World cancer report. Lyon: IARC Press, 2003.197 p.
-
(2003)
World cancer report
, pp. 197
-
-
Ohgaki, H.1
Matsukura, N.2
-
3
-
-
0342514585
-
Molecular epidemiology, pathogenesis and prevention of gastric cancer
-
Stadtlander CT, Waterbor JW. Molecular epidemiology, pathogenesis and prevention of gastric cancer. Carcinogenesis 1999;20:2195-2208
-
(1999)
Carcinogenesis
, vol.20
, pp. 2195-2208
-
-
Stadtlander, C.T.1
Waterbor, J.W.2
-
5
-
-
0036836941
-
Emerging functions of p21-activated kinases in human cancer cells
-
Kumar R, Vadlamudi RK. Emerging functions of p21-activated kinases in human cancer cells. J Cell Physiol 2002;193:133-144
-
(2002)
J Cell Physiol
, vol.193
, pp. 133-144
-
-
Kumar, R.1
Vadlamudi, R.K.2
-
6
-
-
0040056864
-
P21-Activated kinase 1 phosphorylates the death agonist Bad and protects cells from apoptosis
-
DOI 10.1128/MCB.20.2.453-461.2000
-
Schurmann A, Mooney AF, Sanders LC, Sells MA, Wang HG, Reed JC, Bokoch GM. P21-activated kinase 1 phosphorylates the death agonist bad and protects cells from apoptosis. Mol Cell Biol 2000;20:453-461 (Pubitemid 30023086)
-
(2000)
Molecular and Cellular Biology
, vol.20
, Issue.2
, pp. 453-461
-
-
Schurmann, A.1
Mooney, A.F.2
Sanders, L.C.3
Sells, M.A.4
Wang, H.G.5
Reed, J.C.6
Bokoch, G.M.7
-
7
-
-
0034680834
-
Regulatable expression of p21-activated kinase-1 promotes anchorage-independent growth and abnormal organization of mitotic spindles in human epithelial breast cancer cells
-
DOI 10.1074/jbc.M002138200
-
Vadlamudi RK, Adam L, Wang RA, Mandal M, Nguyen D, Sahin A, Chernoff J, Hung MC, Kumar R. Regulatable expression of p21-activated kinase-1 promotes anchorage-independent growth and abnormal organization of mitotic spindles in human epithelial breast cancer cells. J Biol Chem 2000;275:36238-36244 (Pubitemid 30841175)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.46
, pp. 36238-36244
-
-
Vadlamudi, R.K.1
Adam, L.2
Wang, R.-A.3
Mandal, M.4
Nguyen, D.5
Sahin, A.6
Chernoff, J.7
Hung, M.-C.8
Kumar, R.9
-
8
-
-
35648963602
-
JAK2 tyrosine kinase phosphorylates PAK1 and regulates PAK1 activity and functions
-
DOI 10.1074/jbc.M701794200
-
Rider L, Shatrova A, Feener EP, Webb L, Diakonova M. JAK2 tyrosine kinase phosphorylates PAK1 and regulates PAK1 activity and functions. J Biol Chem 2007;282:30985-30996 (Pubitemid 350035237)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.42
, pp. 30985-30996
-
-
Rider, L.1
Shatrova, A.2
Feener, E.P.3
Webb, L.4
Diakonova, M.5
-
9
-
-
0034731505
-
P21-activated kinase (PAK1) is phosphorylated and activated by 3-phosphoinositidedependent kinase-1 (PDK1)
-
King CC, Gardiner EM, Zenke FT, Bohl BP, Newton AC, Hemmings BA, Bokoch GM. P21-activated kinase (PAK1) is phosphorylated and activated by 3-phosphoinositidedependent kinase-1 (PDK1). J Biol Chem 2000;275:41201-41209
-
(2000)
J Biol Chem
, vol.275
, pp. 41201-41209
-
-
King, C.C.1
Gardiner, E.M.2
Zenke, F.T.3
Bohl, B.P.4
Newton, A.C.5
Hemmings, B.A.6
Bokoch, G.M.7
-
10
-
-
0034282225
-
Regulation of anchorage-dependent signal transduction by protein kinase a and p21-activated kinase
-
DOI 10.1038/35023536
-
Howe AK, Juliano RL. Regulation of anchorage-dependent signal transduction by protein kinase A and p21-activated kinase. Nature Cell Biol 2000;2:593-600. (Pubitemid 30742832)
-
(2000)
Nature Cell Biology
, vol.2
, Issue.9
, pp. 593-600
-
-
Howe, A.K.1
Juliano, R.L.2
-
11
-
-
0035907296
-
The mechanism of PAK activation. Autophosphorylation events in both regulatory and kinase domains control activity
-
DOI 10.1074/jbc.M009316200
-
Chong C, Tan L, Lim L, Manser E. The mechanism of Pak activation. Autophosphorylation events in both regulatory and kinase domains control activity. J Biol Chem 2001;276:17347-17353 (Pubitemid 37411545)
-
(2001)
Journal of Biological Chemistry
, vol.276
, Issue.20
, pp. 17347-17353
-
-
Chong, C.1
Tan, L.2
Lim, L.3
Manser, E.4
-
12
-
-
0034680834
-
Regulatable expression of p21-activated kinase-1 promotes anchorage- independent growth and abnormal organization of mitotic spindles in human epithelial breast cancer cells
-
Vadlamudi RK, Adam L, Wang RA, Mandal M, Nguyen D, Sahin A, Chernoff J, Hung MC, Kumar R. Regulatable expression of p21-activated kinase-1 promotes anchorage- independent growth and abnormal organization of mitotic spindles in human epithelial breast cancer cells. J Biol Chem 2000;275:36238-36244
-
(2000)
J Biol Chem
, vol.275
, pp. 36238-36244
-
-
Vadlamudi, R.K.1
Adam, L.2
Wang, R.A.3
Mandal, M.4
Nguyen, D.5
Sahin, A.6
Chernoff, J.7
Hung, M.C.8
Kumar, R.9
-
13
-
-
2542452838
-
Pak-1 expression increases with progression of colorectal carcinomas to metastasis
-
DOI 10.1158/1078-0432.CCR-03-0210
-
Carter JH, Douglass LE, Deddens JA, Colligan BM, Bhatt TR, Pemberton JO, Konicek S, Hom J, Marshall M, Graff JR. Pak-1 expression increases with progression of colorectal carcinomas to metastasis. Clin Cancer Res 2004;10:3448-3456 (Pubitemid 38685452)
-
(2004)
Clinical Cancer Research
, vol.10
, Issue.10
, pp. 3448-3456
-
-
Carter, J.H.1
Douglass, L.E.2
Deddens, J.A.3
Colligan, B.M.4
Bhatt, T.R.5
Pemberton, J.O.6
Konicek, S.7
Hom, J.8
Marshall, M.9
Graff, J.R.10
-
14
-
-
0041423391
-
Combined array comparative genomic hybridization and tissue microarray analysis suggest PAK1 at 11q13.5-q14 as a critical oncogene target in ovarian carcinoma
-
Schraml P, Schwerdtfeger G, Burkhalter F, Raggi A, Schmidt D, Ruffalo T, King W, Wilber K, Mihatsch MJ, Moch H. Combined array comparative genomic hybridization and tissue microarray analysis suggest PAK1 at 11q13.5-q14 as a critical oncogene target in ovarian carcinoma. Am J Pathol 2003;163:985-992 (Pubitemid 37040134)
-
(2003)
American Journal of Pathology
, vol.163
, Issue.3
, pp. 985-992
-
-
Schraml, P.1
Schwerdtfeger, G.2
Burkhalter, F.3
Raggi, A.4
Schmidt, D.5
Ruffalo, T.6
King, W.7
Wilber, K.8
Mihatsch, M.J.9
Moch, H.10
-
15
-
-
34648828070
-
Modulation of p21-activated kinase 1 alters the behavior of renal cell carcinoma
-
O'sullivan GC, Tangney M, Casey G, Ambrose M, Houston A, Barry OP. Modulation of p21-activated kinase 1 alters the behavior of renal cell carcinoma. Int J Cancer 2007;121:1930-1940
-
(2007)
Int J Cancer
, vol.121
, pp. 1930-1940
-
-
O'Sullivan, G.C.1
Tangney, M.2
Casey, G.3
Ambrose, M.4
Houston, A.5
Barry, O.P.6
-
16
-
-
0037107380
-
P21-activated kinase-1 phosphorylates and transactivates estrogen receptor-a and promotes hyperplasia in mammary epithelium
-
DOI 10.1093/emboj/cdf543
-
Wang RA, Mazumdar A, Vadlamudi RK, Kumar R. P21-activated kinase-1 phosphorylates and transactivates estrogen receptor-a and promotes hyperplasia in mammary epithelium. EMBO J 2002;21:5437-5447 (Pubitemid 35231023)
-
(2002)
EMBO Journal
, vol.21
, Issue.20
, pp. 5437-5447
-
-
Wang, R.-A.1
Mazumdar, A.2
Vadlamudi, R.K.3
Kumar, R.4
-
18
-
-
0036711657
-
Filamin is essential in actin cytoskeletal assembly mediated by p21-activated kinase 1
-
DOI 10.1038/ncb838
-
Vadlamudi RK, Li F, Adam L, Nguyen D, Ohta Y, Stossel TP, Kumar R. Filamin is essential in actin cytoskeletal assembly mediated by p21-activated kinase 1. Nat Cell Biol 2002;4:681-690 (Pubitemid 34993704)
-
(2002)
Nature Cell Biology
, vol.4
, Issue.9
, pp. 681-690
-
-
Vadlamudi, R.K.1
Li, F.2
Adam, L.3
Nguyen, D.4
Ohta, Y.5
Stossel, T.P.6
Kumar, R.7
-
19
-
-
0035914037
-
Over-expression of FoxM1 stimulates cyclin B1 expression
-
DOI 10.1016/S0014-5793(01)02915-5, PII S0014579301029155
-
Leung TW, Lin SS, Tsang AC, Tong CS, Ching JC, Leung WY, Gimlich R, Wong GG, Yao KM. Over-expression of FoxM1 stimulates cyclin B1 expression. FEBS Lett 2001;507:59-66. (Pubitemid 33000299)
-
(2001)
FEBS Letters
, vol.507
, Issue.1
, pp. 59-66
-
-
Leung, T.W.C.1
Lin, S.S.W.2
Tsang, A.C.C.3
Tong, C.S.W.4
Ching, J.C.Y.5
Leung, W.Y.6
Gimlich, R.7
Wong, G.G.8
Yao, K.-M.9
-
20
-
-
0032587325
-
IκB-mediated inhibition of virus-induced beta interferon transcription
-
Algarté M, Nguyen H, Heylbroeck C, Lin R, Hiscott J. IκB-mediated inhibition of virus-induced b interferon transcription. J Virol 1999;73:2694-2702 (Pubitemid 29135654)
-
(1999)
Journal of Virology
, vol.73
, Issue.4
, pp. 2694-2702
-
-
Algarte, M.1
Nguyen, H.2
Heylbroeck, C.3
Lin, R.4
Hiscott, J.5
-
21
-
-
34248531653
-
P21-activated protein kinase is overexpressed in hepatocellular carcinoma and enhances cancer metastasis involving c-Jun NH2-terminal kinase activation and paxillin phosphorylation
-
Ching YP, Leong VY, Lee MF, Xu HT, Jin DY, Ng IO. P21-activated protein kinase is overexpressed in hepatocellular carcinoma and enhances cancer metastasis involving c-Jun NH2-terminal kinase activation and paxillin phosphorylation. Cancer Res 2007;67:3601-3608
-
(2007)
Cancer Res
, vol.67
, pp. 3601-3608
-
-
Ching, Y.P.1
Leong, V.Y.2
Lee, M.F.3
Xu, H.T.4
Jin, D.Y.5
Ng, I.O.6
-
22
-
-
0036668638
-
P21-activated kinase 1 interacts with and phosphorylates histone H3 in breast cancer cells
-
DOI 10.1093/embo-reports/kvf157
-
Li F, Adam L, Vadlamudi RK, Zhou H, Sen S, Chernoff J, Mandal M, Kumar R. p21-activated kinase 1 interacts with and phosphorylates histone H3 in breast cancer cells. EMBO Rep 2002;3:767-773 (Pubitemid 34966016)
-
(2002)
EMBO Reports
, vol.3
, Issue.8
, pp. 767-773
-
-
Li, F.1
Adam, L.2
Vadlamudi, R.K.3
Zhou, H.4
Sen, S.5
Chernoff, J.6
Mandal, M.7
Kumar, R.8
-
23
-
-
0346462998
-
P21-activated Kinase-1 Signaling Mediates Cyclin D1 Expression in Mammary Epithelial and Cancer Cells
-
DOI 10.1074/jbc.M309937200
-
Balasenthil S, Sahin AA, Barnes CJ, Wang RA, Pestell RG, Vadlamudi RK, Kumar R. p21-activated kinase-1 signaling mediates cyclin D1 expression in mammary epithelial and cancer cells. J Biol Chem 2004;279:1422-1428 (Pubitemid 38082670)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.2
, pp. 1422-1428
-
-
Balasenthil, S.1
Sahin, A.A.2
Barnes, C.J.3
Wang, R.-A.4
Pestell, R.G.5
Vadlamudi, R.K.6
Kumar, R.7
-
24
-
-
34247540411
-
Regulation of the G2-M cell cycle progression by the ERK5-NFκB signaling pathway
-
DOI 10.1083/jcb.200609166
-
Cude K, Wang Y, Choi HJ, Hsuan SL, Zhang H, Wang CY, Xia Z. Regulation of the G2-M cell cycle progression by the ERK5-NFκB signaling pathway. J Cell Biol 2007;177:253-264 (Pubitemid 46658637)
-
(2007)
Journal of Cell Biology
, vol.177
, Issue.2
, pp. 253-264
-
-
Cude, K.1
Wang, Y.2
Choi, H.-J.3
Hsuan, S.-L.4
Zhang, H.5
Wang, C.-Y.6
Xia, Z.7
-
25
-
-
34447320201
-
Notch inhibition in Kaposi's sarcoma tumor cells leads to mitotic catastrophe through nuclear factor-κB signaling
-
DOI 10.1158/1535-7163.MCT-07-0093
-
Curry CL, Reed LL, Broude E, Golde TE, Miele L, Foreman KE. Notch inhibition in Kaposi's sarcoma tumor cells leads to mitotic catastrophe through nuclear factor-κB signaling. Mol Cancer Ther 2007;6:1983-1992 (Pubitemid 47052488)
-
(2007)
Molecular Cancer Therapeutics
, vol.6
, Issue.7
, pp. 1983-1992
-
-
Curry, C.L.1
Reed, L.L.2
Broude, E.3
Golde, T.E.4
Miele, L.5
Foreman, K.E.6
-
26
-
-
0346690266
-
Activation of p21-Activated Kinase 1-Nuclear Factor κB Signaling by Kaposi's Sarcoma-Associated Herpes Virus G Protein-Coupled Receptor during Cellular Transformation
-
Dadke D, Fryer BH, Golemis EA, Field J. Activation of p21-activated kinase 1-nuclear factor κB signaling by Kaposi's sarcoma-associated herpes virus G protein-coupled receptor during cellular transformation. Cancer Res 2003;63:8837-8847 (Pubitemid 38064063)
-
(2003)
Cancer Research
, vol.63
, Issue.24
, pp. 8837-8847
-
-
Dadke, D.1
Fryer, B.H.2
Golemis, E.A.3
Field, J.4
-
27
-
-
0034733041
-
Stimulation of NFκB activity by multiple signaling pathways requires PAK1
-
DOI 10.1074/jbc.M909860199
-
Frost JA, Swantek JL, Stippec S, Yin MJ, Gaynor R, Cobb MH. Stimulation of. NFκB activity by multiple signaling pathways requires PAK1. J Biol Chem 2000;275:19693-19699 (Pubitemid 30441565)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.26
, pp. 19693-19699
-
-
Frost, J.A.1
Swantek, J.L.2
Stippec, S.3
Yin, M.J.4
Gaynor, R.5
Cobb, M.H.6
-
28
-
-
0034671936
-
P21-activated kinase 1 activates the nuclear factor κB (NF-κB)-inducing kinase-κB kinases NF-κB pathway and proinflammatory cytokines in Helicobacter pylori infection
-
DOI 10.1074/jbc.M007617200
-
Foryst-Ludwig A, Naumann M. p21-activated kinase 1 activates the nuclear factor κB (NF-κB)-inducing kinase-Iκ B kinases NF-κB pathway and proinflammatory cytokines in Helicobacter pylori infection. J Biol Chem 2000;275:39779-39785 (Pubitemid 32059009)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.50
, pp. 39779-39785
-
-
Foryst-Ludwig, A.1
Naumann, M.2
-
29
-
-
26944442735
-
The GIT-associated kinase PAK targets to the centrosome and regulates Aurora-A
-
DOI 10.1016/j.molcel.2005.08.035, PII S1097276505016011
-
Zhao ZS, Lim JP, Ng YW, Lim L, Manser E. The GIT-associated kinase PAK targets to the centrosome and regulates Aurora-A. Mol Cell 2005;20:237-249 (Pubitemid 41484169)
-
(2005)
Molecular Cell
, vol.20
, Issue.2
, pp. 237-249
-
-
Zhao, Z.-S.1
Lim, J.P.2
Ng, Y.-W.3
Lim, L.4
Manser, E.5
-
30
-
-
50049129364
-
P21-activated kinase is required for mitotic progression and regulates Plk1
-
Maroto B, Ye MB, von Lohneysen K, Schnelzer A, Knaus UG. P21-activated kinase is required for mitotic progression and regulates Plk1. Oncogene 2008;27:4900-4908
-
(2008)
Oncogene
, vol.27
, pp. 4900-4908
-
-
Maroto, B.1
Ye, M.B.2
Von Lohneysen, K.3
Schnelzer, A.4
Knaus, U.G.5
|