A low molecular weight zinc2+-dipicolylamine-based probe detects apoptosis during tumour treatment better than an annexin V-based probe

European Radiology

Volumn 24, Issue 2, 2014, Pages 363-370

  Palmowski, Karin ^a,b   Rix, Anne ^a   Lederle, Wiltrud ^a   Behrendt, Florian F ^a   Mottaghy, Felix M ^a,c   Gray, Brian D ^d   Pak, Koon Y ^e   Palmowski, Moritz ^a,e   Kiessling, Fabian ^a  

^a RWTH AACHEN UNIVERSITY   (Germany)

^b UNIVERSITY OF HEIDELBERG   (Germany)

^c MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

^d MOLECULAR TARGETING TECHNOLOGIES INC   (United States)

^e UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

Author keywords

Annexin V; Apoptosis; Molecular imaging; Optical imaging; Therapy monitoring; Tumour; Zn2+ DPA

Indexed keywords

ANNEXINVIVO 750; FLUORODEOXYGLUCOSE F 18; LIPOCORTIN 5; PHOSPHATIDYLSERINE; PSVUE 794; SUNITINIB; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; ZINC DIPICOLYLAMINE; ZINC ION;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIANGIOGENIC THERAPY; APOPTOSIS; ARTICLE; CONTROLLED STUDY; FEMALE; FLUORESCENCE IMAGING; GLUCOSE METABOLISM; HUMAN; HUMAN CELL; IMAGING SYSTEM; IMMUNOHISTOCHEMISTRY; MOLECULAR IMAGING; MOLECULAR PROBE; MOLECULAR WEIGHT; MOUSE; NICK END LABELING; NONHUMAN; ONCOLOGICAL PARAMETERS; PET SCANNER; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SENSITIVITY ANALYSIS; SQUAMOUS CELL CARCINOMA; THERAPY EFFECT; TREATMENT RESPONSE; TUMOR CELL; TUMOR TO MUSCLE RATIO; TUMOR VESSEL DENSITY; UMBILICAL VEIN ENDOTHELIAL CELL;

AMINES; ANGIOGENESIS INHIBITORS; ANIMALS; ANNEXIN A5; APOPTOSIS; CARCINOMA, SQUAMOUS CELL; FEMALE; FLUORODEOXYGLUCOSE F18; HUMANS; IMMUNOHISTOCHEMISTRY; INDOLES; MICE; MICE, NUDE; MOLECULAR PROBES; MOLECULAR WEIGHT; NEOPLASMS, EXPERIMENTAL; ORGANOMETALLIC COMPOUNDS; PICOLINIC ACIDS; PYRROLES; SKIN NEOPLASMS; TUMOR CELLS, CULTURED; ZINC;

EID: 84893311890     PISSN: 09387994     EISSN: 14321084     Source Type: Journal    
DOI: 10.1007/s00330-013-3014-8     Document Type: Article

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