Sepp1UF forms are N-terminal selenoprotein P truncations that have peroxidase activity when coupled with thioredoxin reductase-1

Free Radical Biology and Medicine

Volumn 69, Issue , 2014, Pages 67-76

  Kurokawa, Suguru ^a   Eriksson, Sofi ^b   Rose, Kristie L ^a   Wu, Sen ^c   Motley, Amy K ^a   Hill, Salisha ^a   Winfrey, Virginia P ^a   McDonald, W Hayes ^a   Capecchi, Mario R ^c   Atkins, John F ^c,d   Arnér, Elias S J ^b   Hill, Kristina E ^a   Burk, Raymond F ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b KAROLINSKA INSTITUTE   (Sweden)

^c UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY COLLEGE CORK   (Ireland)

Author keywords

Extracellular peroxidase activity; Free radicals; Megalin; Selenium homeostasis; Selenium containing proteins; Selenoprotein P forms

Indexed keywords

GLUTATHIONE PEROXIDASE 3; HYDROGEN PEROXIDE; MEGALIN; PEROXIDASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE DEHYDROGENASE; SELENIUM; SELENOCYSTEINE; SELENOPROTEIN P; TERT BUTYL HYDROPEROXIDE; THIOREDOXIN; THIOREDOXIN REDUCTASE 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ENDOCYTOSIS; ENZYME ACTIVITY; ENZYME SYNTHESIS; FEMALE; IN VIVO STUDY; KIDNEY PROXIMAL TUBULE; MALE; MASS SPECTROMETRY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN URINE LEVEL; URINALYSIS;

EXTRACELLULAR PEROXIDASE ACTIVITY; FREE RADICALS; MEGALIN; SELENIUM HOMEOSTASIS; SELENIUM-CONTAINING PROTEINS; SELENOPROTEIN P FORMS;

ANIMALS; BIOLOGICAL TRANSPORT; ENDOCYTOSIS; GLUTATHIONE PEROXIDASE; HYDROGEN PEROXIDE; KIDNEY GLOMERULUS; KIDNEY TUBULES, PROXIMAL; MICE; OXIDATION-REDUCTION; PROTEIN STRUCTURE, TERTIARY; SELENOCYSTEINE; SELENOPROTEINS; THIOREDOXIN REDUCTASE 1;

EID: 84893287614     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2014.01.010     Document Type: Article

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