Production of selenoprotein P (Sepp1) by hepatocytes is central to selenium homeostasis

Journal of Biological Chemistry

Volumn 287, Issue 48, 2012, Pages 40414-40424

  Hill, Kristina E ^a   Wu, Sen ^b,d   Motley, Amy K ^a   Stevenson, Teri D ^a   Winfrey, Virginia P ^a   Capecchi, Mario R ^b   Atkins, John F ^b,c   Burk, Raymond F ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY COLLEGE CORK   (Ireland)

^d CHINA AGRICULTURAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN E; CLINICAL MANIFESTATION; EXTRACELLULAR PROTEINS; GLUTATHIONES; HEPATOCYTES; PERIPHERAL TISSUE; PRIMARY STRUCTURES; SELENIUM CONCENTRATIONS; SELENIUM DEFICIENCY; SELENOCYSTEINE; SELENOPROTEIN P; SELENOPROTEINS; WHOLE-BODY;

HISTOLOGY; MAMMALS; MOLECULAR BIOLOGY; PHYSIOLOGY; TISSUE;

SELENIUM;

GLUTATHIONE PEROXIDASE 1; MESSENGER RNA; SELENIUM; SELENOPROTEIN P;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOACCUMULATION; CELL FUNCTION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DIET SUPPLEMENTATION; DOWN REGULATION; DRUG MECHANISM; FEMALE; GENE DELETION; GENE EXPRESSION; GENE LOCATION; HOMEOSTASIS; LIVER CELL; LIVER METABOLISM; LIVER PROTECTION; MALE; METABOLITE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN SYNTHESIS; SELENIUM DEFICIENCY; SEPP1 GENE; TISSUE DISTRIBUTION; TRANSPORT KINETICS; URINARY EXCRETION;

ANIMALS; BIOLOGICAL TRANSPORT; FEMALE; HEPATOCYTES; HOMEOSTASIS; LIVER; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; SELENIUM; SELENOPROTEIN P;

MUS;

EID: 84869992888     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.421404     Document Type: Article

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