메뉴 건너뛰기




Volumn 19, Issue 1, 2014, Pages 94-102

Echinacea purpurea (L.) Moench modulates human T-cell cytokine response

Author keywords

Cytokine response; Echinacea; Human T cell density; Immune modulation; Neutral and weakly acidic water soluble extract; Polysaccharides and phenolic compounds; Small molecule fingerprint analysis

Indexed keywords

CAFTARIC ACID; CICHORIC ACID; CYNARINE; ECHINACEA PURPUREA L MOENCH EXTRACT; GAMMA INTERFERON; HYDROXYACID; IMMUNOMODULATING AGENT; INTERLEUKIN 2; IONOMYCIN; PHORBOL 13 ACETATE 12 MYRISTATE; PLANT EXTRACT; POLYSACCHARIDE; UNCLASSIFIED DRUG;

EID: 84893273699     PISSN: 15675769     EISSN: 18781705     Source Type: Journal    
DOI: 10.1016/j.intimp.2013.12.019     Document Type: Article
Times cited : (30)

References (60)
  • 1
    • 34248147668 scopus 로고    scopus 로고
    • Use of herbs among adults based on evidence-based indications: Findings from the National Health Interview Survey
    • A. Bardia, N.L. Nisly, M.B. Zimmerman, B.M. Gryzlak, and R.B. Wallace Use of herbs among adults based on evidence-based indications: findings from the National Health Interview Survey Mayo Clin Proc 82 2007 561 566 (Pubitemid 46709424)
    • (2007) Mayo Clinic Proceedings , vol.82 , Issue.5 , pp. 561-566
    • Bardia, A.1    Nisly, N.L.2    Zimmerman, M.B.3    Gryzlak, B.M.4    Wallace, R.B.5
  • 2
    • 22844438903 scopus 로고    scopus 로고
    • Echinacea species (Echinacea angustifolia (DC.) Hell., Echinacea pallida (Nutt.) Nutt., Echinacea purpurea (L.) Moench): A review of their chemistry, pharmacology and clinical properties
    • DOI 10.1211/0022357056127
    • J. Barnes, L.A. Anderson, S. Gibbons, and J.D. Phillipson Echinacea species (Echinacea angustifolia (DC.) Hell., Echinacea pallida (Nutt.) Nutt., Echinacea purpurea (L.) Moench): a review of their chemistry, pharmacology and clinical properties J Pharm Pharmacol 57 2005 929 954 (Pubitemid 41039828)
    • (2005) Journal of Pharmacy and Pharmacology , vol.57 , Issue.8 , pp. 929-954
    • Barnes, J.1    Anderson, L.A.2    Gibbons, S.3    Phillipson, J.D.4
  • 3
    • 14944386159 scopus 로고    scopus 로고
    • Treatment of the common cold with echinacea: A structured review
    • DOI 10.1086/428061
    • T.J. Caruso, and J.M. Gwaltney Jr. Treatment of the common cold with Echinacea: a structured review Clin Infect Dis 40 2005 807 810 (Pubitemid 40365498)
    • (2005) Clinical Infectious Diseases , vol.40 , Issue.6 , pp. 807-810
    • Caruso, T.J.1    Gwaltney Jr., J.M.2
  • 4
    • 34250758071 scopus 로고    scopus 로고
    • Evaluation of echinacea for the prevention and treatment of the common cold: A meta-analysis
    • DOI 10.1016/S1473-3099(07)70160-3, PII S1473309907701603
    • S.A. Shah, S. Sander, C.M. White, M. Rinaldi, and C.I. Coleman Evaluation of Echinacea for the prevention and treatment of the common cold: a meta-analysis Lancet Infect Dis 7 2007 473 480 (Pubitemid 46962345)
    • (2007) Lancet Infectious Diseases , vol.7 , Issue.7 , pp. 473-480
    • Shah, S.A.1    Sander, S.2    White, C.M.3    Rinaldi, M.4    Coleman, C.I.5
  • 6
    • 45349106060 scopus 로고    scopus 로고
    • Echinacea for preventing and treating the common cold
    • DOI 10.1055/s-2007-993766
    • K. Woelkart, K. Linde, and R. Bauer Echinacea for preventing and treating the common cold Planta Med 74 2008 633 637 (Pubitemid 351846777)
    • (2008) Planta Medica , vol.74 , Issue.6 , pp. 633-637
    • Woelkart, K.1    Linde, K.2    Bauer, R.3
  • 7
    • 33646200102 scopus 로고    scopus 로고
    • Echinacea in the prevention of induced rhinovirus colds: A meta-analysis
    • R. Schoop, P. Klein, A. Suter, and S.L. Johnston Echinacea in the prevention of induced rhinovirus colds: a meta-analysis Clin Ther 28 2006 174 183
    • (2006) Clin Ther , vol.28 , pp. 174-183
    • Schoop, R.1    Klein, P.2    Suter, A.3    Johnston, S.L.4
  • 8
  • 9
    • 72449195360 scopus 로고    scopus 로고
    • Anti-viral properties and mode of action of standardized Echinacea purpurea extract against highly pathogenic avian influenza virus (H5N1, H7N7) and swine-origin H1N1 (S-OIV)
    • S. Pleschka, M. Stein, R. Schoop, and J.B. Hudson Anti-viral properties and mode of action of standardized Echinacea purpurea extract against highly pathogenic avian influenza virus (H5N1, H7N7) and swine-origin H1N1 (S-OIV) Virol J 6 2009 197
    • (2009) Virol J , vol.6 , pp. 197
    • Pleschka, S.1    Stein, M.2    Schoop, R.3    Hudson, J.B.4
  • 10
    • 0036747149 scopus 로고    scopus 로고
    • Antiviral activity of characterized extracts from Echinacea spp. (Heliantheae: Asteraceae) against Herpes simplex virus (HSV-I)
    • DOI 10.1055/s-2002-34397
    • S.E. Binns, J. Hudson, S. Merali, and J.T. Arnason Antiviral activity of characterized extracts from Echinacea spp. (Heliantheae: Asteraceae) against herpes simplex virus (HSV-I) Planta Med 68 2002 780 783 (Pubitemid 35177620)
    • (2002) Planta Medica , vol.68 , Issue.9 , pp. 780-783
    • Binns, S.E.1    Hudson, J.2    Merali, S.3    Arnason, J.T.4
  • 12
    • 0037134631 scopus 로고    scopus 로고
    • Phytochemical variation in Echinacea from roots and flowerheads of wild and cultivated populations
    • DOI 10.1021/jf011439t
    • S.E. Binns, J.F. Livesey, J.T. Arnason, and B.R. Baum Phytochemical variation in Echinacea from roots and flowerheads of wild and cultivated populations J Agric Food Chem 50 2002 3673 3687 (Pubitemid 34640689)
    • (2002) Journal of Agricultural and Food Chemistry , vol.50 , Issue.13 , pp. 3673-3687
    • Binns, S.E.1    Livesey, J.F.2    Arnason, J.T.3    Baum, B.R.4
  • 13
    • 34447500693 scopus 로고    scopus 로고
    • The role of alkamides as an active principle of Echinacea
    • DOI 10.1055/s-2007-981531
    • K. Woelkart, and R. Bauer The role of alkamides as an active principle of Echinacea Planta Med 73 2007 615 623 (Pubitemid 47066152)
    • (2007) Planta Medica , vol.73 , Issue.7 , pp. 615-623
    • Woelkart, K.1    Bauer, R.2
  • 14
    • 33846241704 scopus 로고    scopus 로고
    • Liver enzyme-mediated oxidation of Echinacea purpurea alkylamides: Production of novel metabolites and changes in immunomodulatory activity
    • DOI 10.1055/s-2006-951718
    • N.B. Cech, K. Tutor, B.A. Doty, K. Spelman, M. Sasagawa, and G.M. Raner et al. Liver enzyme-mediated oxidation of Echinacea purpurea alkylamides: production of novel metabolites and changes in immunomodulatory activity Planta Med 72 2006 1372 1377 (Pubitemid 46102390)
    • (2006) Planta Medica , vol.72 , Issue.15 , pp. 1372-1377
    • Cech, N.B.1    Tutor, K.2    Doty, B.A.3    Spelman, K.4    Sasagawa, M.5    Raner, G.M.6    Wenner, C.A.7
  • 15
    • 82155173478 scopus 로고    scopus 로고
    • Effects of Chemically Characterized Fractions from Aerial Parts of Echinacea purpurea and E. Angustifolia on Myelopoiesis in Rats
    • S. Ramasahayam, H.N. Baraka, F.M. Abdel Bar, B.S. Abuasal, M.P. Widrlechner, and K.A. El Sayed et al. Effects of Chemically Characterized Fractions from Aerial Parts of Echinacea purpurea and E. angustifolia on Myelopoiesis in Rats Planta Med 77 2011 1883 1889
    • (2011) Planta Med , vol.77 , pp. 1883-1889
    • Ramasahayam, S.1    Baraka, H.N.2    Abdel Bar, F.M.3    Abuasal, B.S.4    Widrlechner, M.P.5    El Sayed, K.A.6
  • 16
  • 17
    • 77952422312 scopus 로고    scopus 로고
    • Echinacea purpurea aerial extract alters course of influenza infection in mice
    • D. Fusco, X. Liu, C. Savage, Y. Taur, W. Xiao, and E. Kennelly et al. Echinacea purpurea aerial extract alters course of influenza infection in mice Vaccine 28 2010 3956 3962
    • (2010) Vaccine , vol.28 , pp. 3956-3962
    • Fusco, D.1    Liu, X.2    Savage, C.3    Taur, Y.4    Xiao, W.5    Kennelly, E.6
  • 18
    • 33144484366 scopus 로고    scopus 로고
    • Echinacea extracts modulate the pattern of chemokine and cytokine secretion in rhinovirus-infected and uninfected epithelial cells
    • DOI 10.1002/ptr.1824
    • M. Sharma, J.T. Arnason, A. Burt, and J.B. Hudson Echinacea extracts modulate the pattern of chemokine and cytokine secretion in rhinovirus-infected and uninfected epithelial cells Phytother Res 20 2006 147 152 (Pubitemid 43266841)
    • (2006) Phytotherapy Research , vol.20 , Issue.2 , pp. 147-152
    • Sharma, M.1    Arnason, J.T.2    Burt, A.3    Hudson, J.B.4
  • 22
    • 70349912047 scopus 로고    scopus 로고
    • Endogenous levels of Echinacea alkylamides and ketones are important contributors to the inhibition of prostaglandin E2 and nitric oxide production in cultured macrophages
    • C.A. LaLone, L. Rizshsky, K.D. Hammer, L. Wu, A.K. Solco, and M. Yum et al. Endogenous levels of Echinacea alkylamides and ketones are important contributors to the inhibition of prostaglandin E2 and nitric oxide production in cultured macrophages J Agric Food Chem 57 2009 8820 8830
    • (2009) J Agric Food Chem , vol.57 , pp. 8820-8830
    • Lalone, C.A.1    Rizshsky, L.2    Hammer, K.D.3    Wu, L.4    Solco, A.K.5    Yum, M.6
  • 23
    • 81255138129 scopus 로고    scopus 로고
    • Echinacea alkamides prevent lipopolysaccharide/D-galactosamine-induced acute hepatic injury through JNK pathway-mediated HO-1 expression
    • C.C. Hou, C.C. Huang, and L.F. Shyur Echinacea alkamides prevent lipopolysaccharide/D-galactosamine-induced acute hepatic injury through JNK pathway-mediated HO-1 expression J Agric Food Chem 59 2011 11966 11974
    • (2011) J Agric Food Chem , vol.59 , pp. 11966-11974
    • Hou, C.C.1    Huang, C.C.2    Shyur, L.F.3
  • 24
    • 77955696239 scopus 로고    scopus 로고
    • Enrichment of Echinacea angustifolia with Bauer alkylamide 11 and Bauer ketone 23 increased anti-inflammatory potential through interference with cox-2 enzyme activity
    • C.A. LaLone, N. Huang, L. Rizshsky, L. Yum, N. Singh, and C. Hauck et al. Enrichment of Echinacea angustifolia with Bauer alkylamide 11 and Bauer ketone 23 increased anti-inflammatory potential through interference with cox-2 enzyme activity J Agric Food Chem 58 2009 8573 8584
    • (2009) J Agric Food Chem , vol.58 , pp. 8573-8584
    • Lalone, C.A.1    Huang, N.2    Rizshsky, L.3    Yum, L.4    Singh, N.5    Hauck, C.6
  • 25
    • 0025973476 scopus 로고
    • Application of purified polysaccharides from cell cultures of the plant Echinacea purpurea to mice mediates protection against systemic infections with Listeria monocytogenes and Candida albicans
    • J. Roesler, C. Steinmuller, A. Kiderlen, A. Emmendorffer, H. Wagner, and M.L. Lohmann-Matthes Application of purified polysaccharides from cell cultures of the plant Echinacea purpurea to mice mediates protection against systemic infections with Listeria monocytogenes and Candida albicans Int J Immunopharmacol 13 1991 27 37
    • (1991) Int J Immunopharmacol , vol.13 , pp. 27-37
    • Roesler, J.1    Steinmuller, C.2    Kiderlen, A.3    Emmendorffer, A.4    Wagner, H.5    Lohmann-Matthes, M.L.6
  • 26
    • 0027184406 scopus 로고
    • Polysaccharides isolated from plant cell cultures of Echinacea purpurea enhance the resistance of immunosuppressed mice against systemic infections with Candida albicans and Listeria monocytogenes
    • C. Steinmuller, J. Roesler, E. Grottrup, G. Franke, H. Wagner, and M.L. Lohmann-Matthes Polysaccharides isolated from plant cell cultures of Echinacea purpurea enhance the resistance of immunosuppressed mice against systemic infections with Candida albicans and Listeria monocytogenes Int J Immunopharmacol 15 1993 605 614 (Pubitemid 23216864)
    • (1993) International Journal of Immunopharmacology , vol.15 , Issue.5 , pp. 605-614
    • Steinmuller, C.1    Roesler, J.2    Grottrup, E.3    Franke, G.4    Wagner, H.5    Lohmann-Matthes, M.-L.6
  • 30
    • 84893244054 scopus 로고
    • Miniaturization of three carbohydrate analyses using a microsample plate reader miniaturization of three carbohydrate analyses using a microsample plate reader
    • J. Fox, and J.F. DaR Miniaturization of three carbohydrate analyses using a microsample plate reader miniaturization of three carbohydrate analyses using a microsample plate reader Anal Chem 195 1991 09 96
    • (1991) Anal Chem , vol.195 , pp. 09-96
    • Fox, J.1    Dar, J.F.2
  • 31
    • 55449135099 scopus 로고    scopus 로고
    • Pre-column derivatization and RP-HPLC determination of free amino acids in plasma and its application in inborn aminoacidopathies screening
    • J. Zheng, Y.J. Gu, S.P. Yan, L.G. Ma, D.H. Mu, and G.X. Li Pre-column derivatization and RP-HPLC determination of free amino acids in plasma and its application in inborn aminoacidopathies screening J Instrum Anal 24 2005 22 25
    • (2005) J Instrum Anal , vol.24 , pp. 22-25
    • Zheng, J.1    Gu, Y.J.2    Yan, S.P.3    Ma, L.G.4    Mu, D.H.5    Li, G.X.6
  • 32
    • 33645381049 scopus 로고    scopus 로고
    • Immuno-suppressive effect of blocking the CD28 signaling pathway in T-cells by an active component of Echinacea found by a novel pharmaceutical screening method
    • G.C. Dong, P.H. Chuang, M.D. Forrest, Y.C. Lin, and H.M. Chen Immuno-suppressive effect of blocking the CD28 signaling pathway in T-cells by an active component of Echinacea found by a novel pharmaceutical screening method J Med Chem 49 2006 1845 1854
    • (2006) J Med Chem , vol.49 , pp. 1845-1854
    • Dong, G.C.1    Chuang, P.H.2    Forrest, M.D.3    Lin, Y.C.4    Chen, H.M.5
  • 33
    • 36749072576 scopus 로고    scopus 로고
    • Echinacea alkylamides modulate induced immune responses in T-cells
    • DOI 10.1016/j.fitote.2007.07.012, PII S0367326X07001979
    • A. Matthias, L. Banbury, K.M. Bone, D.N. Leach, and R.P. Lehmann Echinacea alkylamides modulate induced immune responses in T-cells Fitoterapia 79 2008 53 58 (Pubitemid 350216287)
    • (2008) Fitoterapia , vol.79 , Issue.1 , pp. 53-58
    • Matthias, A.1    Banbury, L.2    Bone, K.M.3    Leach, D.N.4    Lehmann, R.P.5
  • 34
    • 33646571138 scopus 로고    scopus 로고
    • Echinacea alkylamides inhibit interleukin-2 production by Jurkat T cells
    • DOI 10.1016/j.intimp.2006.02.003, PII S1567576906000622
    • M. Sasagawa, N.B. Cech, D.E. Gray, G.W. Elmer, and C.A. Wenner Echinacea alkylamides inhibit interleukin-2 production by Jurkat T cells Int Immunopharmacol 6 2006 1214 1221 (Pubitemid 43728177)
    • (2006) International Immunopharmacology , vol.6 , Issue.7 , pp. 1214-1221
    • Sasagawa, M.1    Cech, N.B.2    Gray, D.E.3    Elmer, G.W.4    Wenner, C.A.5
  • 35
    • 0002626655 scopus 로고
    • Plant phenolics
    • J.B. Harborne, Academic Press London, IK
    • R. Ibrahim, and D. Barron Plant phenolics J.B. Harborne, Methods in Plant Biochemistry 1989 Academic Press London, IK 75
    • (1989) Methods in Plant Biochemistry , pp. 75
    • Ibrahim, R.1    Barron, D.2
  • 36
    • 0036628708 scopus 로고    scopus 로고
    • Immunological studies of Revitonil®, a phytopharmaceutical containing Echinacea purpurea and Glycyrrhiza glabra root extract
    • H. Wagner, and K. Jurcic Immunological studies of Revitonil, a phytopharmaceutical containing Echinacea purpurea and Glycyrrhiza glabra root extract Phytomedicine 9 2002 390 397 (Pubitemid 34920161)
    • (2002) Phytomedicine , vol.9 , Issue.5 , pp. 390-397
    • Wagner, H.1    Jurcic, K.2
  • 37
  • 39
    • 0001665797 scopus 로고
    • Structural analysis of a 4-0-methyl-glucuronoarabinoxylan with immune-stimulating activity from Echinacea purpurea
    • A. Proksch, and H. Wagner Structural analysis of a 4-0-methyl- glucuronoarabinoxylan with immune-stimulating activity from Echinacea purpurea Phytochemistry 26 1987 1989 1993
    • (1987) Phytochemistry , vol.26 , pp. 1989-1993
    • Proksch, A.1    Wagner, H.2
  • 41
    • 21544451431 scopus 로고    scopus 로고
    • In vitro and in vivo immune stimulating effects of a new standardized Echinacea angustifolia root extract (Polinacea™)
    • DOI 10.1016/j.fitote.2005.02.001, PII S0367326X05000481
    • P. Morazzoni, A. Cristoni, F. Di Pierro, C. Avanzini, D. Ravarino, and S. Stornello et al. In vitro and in vivo immune stimulating effects of a new standardized Echinacea angustifolia root extract (Polinacea) Fitoterapia 76 2005 401 411 (Pubitemid 40922599)
    • (2005) Fitoterapia , vol.76 , Issue.5 , pp. 401-411
    • Morazzoni, P.1    Cristoni, A.2    Di Pierro, F.3    Avanzini, C.4    Ravarino, D.5    Stornello, S.6    Zucca, M.7    Musso, T.8
  • 42
    • 33644813470 scopus 로고    scopus 로고
    • Bioavailability of echinacea constituents: Caco-2 monolayers and pharmacokinetics of the alkylamides and caffeic acid conjugates
    • DOI 10.3390/10101242
    • A. Matthias, K.G. Penman, N.J. Matovic, K.M. Bone, J.J. De Voss, and R.P. Lehmann Bioavailability of Echinacea constituents: Caco-2 monolayers and pharmacokinetics of the alkylamides and caffeic acid conjugates Molecules 10 2005 1242 1251 (Pubitemid 43349745)
    • (2005) Molecules , vol.10 , Issue.10 , pp. 1242-1251
    • Matthias, A.1    Penman, K.G.2    Matovic, N.J.3    Bone, K.M.4    De Voss, J.J.5    Lehmann, R.P.6
  • 43
    • 84863249916 scopus 로고    scopus 로고
    • Adjuvant activity of Chinese herbal polysaccharides in inactivated veterinary rabies vaccines
    • Y. Liu, S. Zhang, F. Zhang, and R. Hu Adjuvant activity of Chinese herbal polysaccharides in inactivated veterinary rabies vaccines Int J Biol Macromol 50 2012 598 602
    • (2012) Int J Biol Macromol , vol.50 , pp. 598-602
    • Liu, Y.1    Zhang, S.2    Zhang, F.3    Hu, R.4
  • 45
    • 58549108464 scopus 로고    scopus 로고
    • Blocking effect of an immuno-suppressive agent, cynarin, on CD28 of T-cell receptor
    • G.C. Dong, P.H. Chuang, K.C. Chang, P.S. Jan, P.I. Hwang, and H.B. Wu et al. Blocking effect of an immuno-suppressive agent, cynarin, on CD28 of T-cell receptor Pharm Res 26 2009 375 381
    • (2009) Pharm Res , vol.26 , pp. 375-381
    • Dong, G.C.1    Chuang, P.H.2    Chang, K.C.3    Jan, P.S.4    Hwang, P.I.5    Wu, H.B.6
  • 46
    • 45349106987 scopus 로고    scopus 로고
    • Immunomodulatory lipids in plants: Plant fatty acid amides and the human endocannabinoid system
    • DOI 10.1055/s-2008-1034302
    • J. Gertsch Immunomodulatory lipids in plants: plant fatty acid amides and the human endocannabinoid system Planta Med 74 2008 638 650 (Pubitemid 351846778)
    • (2008) Planta Medica , vol.74 , Issue.6 , pp. 638-650
    • Gertsch, J.1
  • 47
    • 33744916587 scopus 로고    scopus 로고
    • Alkylamides from Echinacea are a new class of cannabinomimetics: Cannabinoid type 2 receptor-dependent and -independent immunomodulatory effects
    • DOI 10.1074/jbc.M601074200
    • S. Raduner, A. Majewska, J.Z. Chen, X.Q. Xie, J. Hamon, and B. Faller et al. Alkylamides from Echinacea are a new class of cannabinomimetics. Cannabinoid type 2 receptor-dependent and -independent immunomodulatory effects J Biol Chem 281 2006 14192 14206 (Pubitemid 43848347)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.20 , pp. 14192-14206
    • Raduner, S.1    Majewska, A.2    Chen, J.-Z.3    Xie, X.-Q.4    Hamon, J.5    Faller, B.6    Altmann, K.-H.7    Gertsch, J.8
  • 48
    • 70249113423 scopus 로고    scopus 로고
    • Role for PPARgamma in IL-2 inhibition in T cells by Echinacea-derived undeca-2E-ene-8,10-diynoic acid isobutylamide
    • K. Spelman, K. Iiams-Hauser, N.B. Cech, E.W. Taylor, N. Smirnoff, and C.A. Wenner Role for PPARgamma in IL-2 inhibition in T cells by Echinacea-derived undeca-2E-ene-8,10-diynoic acid isobutylamide Int Immunopharmacol 9 2009 1260 1264
    • (2009) Int Immunopharmacol , vol.9 , pp. 1260-1264
    • Spelman, K.1    Iiams-Hauser, K.2    Cech, N.B.3    Taylor, E.W.4    Smirnoff, N.5    Wenner, C.A.6
  • 49
    • 33646596315 scopus 로고    scopus 로고
    • Binding studies of an arabinogalactan-protein from Echinacea purpurea to leucocytes
    • DOI 10.1016/j.phymed.2005.01.017, PII S0944711305001650
    • S. Thude, B. Classen, W. Blaschek, D. Barz, and H. Thude Binding studies of an arabinogalactan-protein from Echinacea purpurea to leucocytes Phytomedicine 13 2006 425 427 (Pubitemid 43728729)
    • (2006) Phytomedicine , vol.13 , Issue.6 , pp. 425-427
    • Thude, S.1    Classen, B.2    Blaschek, W.3    Barz, D.4    Thude, H.5
  • 50
    • 33750957816 scopus 로고    scopus 로고
    • Modulatory effects of Echinacea purpurea extracts on human dendritic cells: A cell- and gene-based study
    • C.Y. Wang, M.T. Chiao, P.J. Yen, W.C. Huang, C.C. Hou, and S.C. Chien et al. Modulatory effects of Echinacea purpurea extracts on human dendritic cells: a cell- and gene-based study Genomics 88 2006 801 808
    • (2006) Genomics , vol.88 , pp. 801-808
    • Wang, C.Y.1    Chiao, M.T.2    Yen, P.J.3    Huang, W.C.4    Hou, C.C.5    Chien, S.C.6
  • 51
    • 77958552759 scopus 로고    scopus 로고
    • Stimulatory effect of Echinacea purpurea extract on the trafficking activity of mouse dendritic cells: Revealed by genomic and proteomic analyses
    • S.Y. Yin, W.H. Wang, B.X. Wang, K. Aravindaram, P.I. Hwang, and H.M. Wu et al. Stimulatory effect of Echinacea purpurea extract on the trafficking activity of mouse dendritic cells: revealed by genomic and proteomic analyses BMC Genomics 11 2010 612
    • (2010) BMC Genomics , vol.11 , pp. 612
    • Yin, S.Y.1    Wang, W.H.2    Wang, B.X.3    Aravindaram, K.4    Hwang, P.I.5    Wu, H.M.6
  • 54
    • 67349209561 scopus 로고    scopus 로고
    • Synergistic immunomopharmacological effects of N-alkylamides in Echinacea purpurea herbal extracts
    • A. Chicca, S. Raduner, F. Pellati, T. Strompen, K.H. Altmann, and R. Schoop et al. Synergistic immunomopharmacological effects of N-alkylamides in Echinacea purpurea herbal extracts Int Immunopharmacol 9 2009 850 858
    • (2009) Int Immunopharmacol , vol.9 , pp. 850-858
    • Chicca, A.1    Raduner, S.2    Pellati, F.3    Strompen, T.4    Altmann, K.H.5    Schoop, R.6
  • 55
    • 77957245871 scopus 로고    scopus 로고
    • Echinacea and its alkylamides: Effects on the influenza A-induced secretion of cytokines, chemokines, and PGE from RAW 264.7 macrophage-like cells
    • N.B. Cech, V. Kandhi, J.M. Davis, A. Hamilton, D. Eads, and S.M. Laster Echinacea and its alkylamides: effects on the influenza A-induced secretion of cytokines, chemokines, and PGE from RAW 264.7 macrophage-like cells Int Immunopharmacol 10 2010 1268 1278
    • (2010) Int Immunopharmacol , vol.10 , pp. 1268-1278
    • Cech, N.B.1    Kandhi, V.2    Davis, J.M.3    Hamilton, A.4    Eads, D.5    Laster, S.M.6
  • 56
    • 57849101746 scopus 로고    scopus 로고
    • Variability in in vitro macrophage activation by commercially diverse bulk Echinacea plant material is predominantly due to bacterial lipoproteins and lipopolysaccharides
    • H. Tamta, N.D. Pugh, P. Balachandran, R. Moraes, J. Sumiyanto, and D.S. Pasco Variability in in vitro macrophage activation by commercially diverse bulk Echinacea plant material is predominantly due to bacterial lipoproteins and lipopolysaccharides J Agric Food Chem 56 2008 10552 10556
    • (2008) J Agric Food Chem , vol.56 , pp. 10552-10556
    • Tamta, H.1    Pugh, N.D.2    Balachandran, P.3    Moraes, R.4    Sumiyanto, J.5    Pasco, D.S.6
  • 57
    • 0019123552 scopus 로고
    • Biochemical and biological characterization of lymphocyte regulatory molecules. V. Identification of an interleukin 2-producing human leukemia T cell line
    • DOI 10.1084/jem.152.6.1709
    • S. Gillis, and J. Watson Biochemical and biological characterization of lymphocyte regulatory molecules. V. Identification of an interleukin 2-producing human leukemia T cell line J Exp Med 152 1980 1709 1719 (Pubitemid 11210348)
    • (1980) Journal of Experimental Medicine , vol.152 , Issue.6 , pp. 1709-1719
    • Gillis, S.1    Watson, J.2
  • 58
    • 77952738203 scopus 로고    scopus 로고
    • Differential cytokine regulation by NF-kappaB and AP-1 in Jurkat T-cells
    • H. Khalaf, J. Jass, and P.E. Olsson Differential cytokine regulation by NF-kappaB and AP-1 in Jurkat T-cells BMC Immunol 11 2010 26
    • (2010) BMC Immunol , vol.11 , pp. 26
    • Khalaf, H.1    Jass, J.2    Olsson, P.E.3
  • 59
    • 78149483844 scopus 로고    scopus 로고
    • IL-2 mRNA stabilization upon PMA stimulation is dependent on NF90-Ser647 phosphorylation by protein kinase CbetaI
    • P. Zhu, W. Jiang, L. Cao, W. Yu, Y. Pei, and X. Yang et al. IL-2 mRNA stabilization upon PMA stimulation is dependent on NF90-Ser647 phosphorylation by protein kinase CbetaI J Immunol 185 2010 5140 5149
    • (2010) J Immunol , vol.185 , pp. 5140-5149
    • Zhu, P.1    Jiang, W.2    Cao, L.3    Yu, W.4    Pei, Y.5    Yang, X.6
  • 60
    • 36549003590 scopus 로고    scopus 로고
    • The effect of Echinacea purpurea, Astragalus membranaceus and Glycyrrhiza glabra on CD25 expression in humans: A pilot study
    • DOI 10.1002/ptr.2207
    • H. Zwickey, J. Brush, C.M. Iacullo, E. Connelly, W.L. Gregory, and A. Soumyanath et al. The effect of Echinacea purpurea, Astragalus membranaceus and Glycyrrhiza glabra on CD25 expression in humans: a pilot study Phytother Res 21 2007 1109 1112 (Pubitemid 350190313)
    • (2007) Phytotherapy Research , vol.21 , Issue.11 , pp. 1109-1112
    • Zwickey, H.1    Brush, J.2    Iacullo, C.M.3    Connelly, E.4    Gregory, W.L.5    Soumyanath, A.6    Buresh, R.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.