Intestinal epithelial apoptosis initiates gut mucosal injury during extracorporeal membrane oxygenation in the newborn piglet

Laboratory Investigation

Volumn 94, Issue 2, 2014, Pages 150-160

  Mohankumar, Krishnan ^a   Killingsworth, Cheryl R ^b   Britt McIlwain, R ^b   Timpa, Joseph G ^b   Jagadeeswaran, Ramasamy ^a   Namachivayam, Kopperuncholan ^c   Kurundkar, Ashish R ^c   Kelly, David R ^c   Garzon, Steven A ^a   Maheshwari, Akhil ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^c University of Alabama at Birmingham   (United States)

Author keywords

apoptotic; ECMO; extracorporeal circulation; mucosal injury; neonate

Indexed keywords

CASPASE 8; CASPASE 9; FAS LIGAND; FATTY ACID BINDING PROTEIN 2; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL ISOLATION; CELL SELECTION; CONTROLLED STUDY; CRYPT CELL; ENZYME IMMUNOASSAY; EXTRACORPOREAL OXYGENATION; FLUORESCENCE ANALYSIS; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; INTESTINE EPITHELIUM CELL; INTESTINE INJURY; INTESTINE MUCOSA; INTESTINE VILLUS; MAST CELL; NEWBORN; NICK END LABELING; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PIGLET; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ANIMALS; ANIMALS, NEWBORN; APOPTOSIS; BLOTTING, WESTERN; CASPASE 8; CASPASE 9; CELL NUCLEUS; DNA PRIMERS; ENZYME-LINKED IMMUNOSORBENT ASSAY; EXTRACORPOREAL MEMBRANE OXYGENATION; FAS LIGAND PROTEIN; FATTY ACID-BINDING PROTEINS; FLOW CYTOMETRY; IMMUNOHISTOCHEMISTRY; IN SITU NICK-END LABELING; INTESTINAL MUCOSA; P38 MITOGEN-ACTIVATED PROTEIN KINASES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; STATISTICS, NONPARAMETRIC; SWINE;

EID: 84893225557     PISSN: 00236837     EISSN: 15300307     Source Type: Journal    
DOI: 10.1038/labinvest.2013.149     Document Type: Article

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