Streptococcus pneumoniae serine protease HtrA, but not SFP or PrtA, is a major virulence factor in pneumonia

PLoS ONE

Volumn 8, Issue 11, 2013, Pages

  De Stoppelaar, Sacha F ^a   Bootsma, Hester J ^b   Zomer, Aldert ^b   Roelofs, Joris J T H ^a   Hermans, Peter W M ^b   Van 't Veer, Cornelis ^a   Van Der Poll, Tom ^a  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

^b RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN HTRA; PROTEIN PRTA; PROTEIN SFP; SERINE PROTEINASE; UNCLASSIFIED DRUG; VIRULENCE FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL GENOME; BACTERIAL GROWTH; BACTERIAL LOAD; BACTERIAL VIRULENCE; BACTERIUM MUTANT; CONTROLLED STUDY; FEMALE; IN VITRO STUDY; IN VIVO STUDY; INDEL MUTATION; LUNG INFILTRATE; MALE; MOUSE; NONHUMAN; PROTEIN FUNCTION; RESPIRATORY TRACT INFLAMMATION; STREPTOCOCCUS PNEUMONIA; STREPTOCOCCUS PNEUMONIAE;

ANIMALS; BACTERIAL PROTEINS; COLONY COUNT, MICROBIAL; FEMALE; GENE KNOCKOUT TECHNIQUES; GENOME, BACTERIAL; LUNG; MALE; MICE; MUTAGENESIS, INSERTIONAL; PNEUMONIA, PNEUMOCOCCAL; SERINE PROTEASES; STREPTOCOCCUS PNEUMONIAE; VIRULENCE FACTORS;

EID: 84893191324     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0080062     Document Type: Article

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