Estimation of retinal ganglion cell loss in glaucomatous eyes with a relative afferent pupillary defect

Investigative Ophthalmology and Visual Science

Volumn 55, Issue 1, 2013, Pages 513-522

  Tatham, Andrew J ^a   Meira Freitas, Daniel ^a   Weinreb, Robert N ^a   Marvasti, Amir H ^a   Zangwill, Linda M ^a   Medeiros, Felipe A ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Glaucoma; Pupillograph; Pupils

Indexed keywords

ADULT; AFFERENT PUPILLARY DEFECT; ARTICLE; CELL LOSS; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; DISEASE SEVERITY; FEMALE; GLAUCOMA; HUMAN; INTRAOCULAR PRESSURE; MAJOR CLINICAL STUDY; MALE; OPTIC DISK; PRIORITY JOURNAL; PUPILLOMETRY; RETINA GANGLION CELL; SCORING SYSTEM; SPECTRAL DOMAIN OPTICAL COHERENCE TOMOGRAPHY; VISUAL ACUITY; VISUAL FIELD; VISUAL STIMULATION;

EID: 84893189310     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.13-12921     Document Type: Article

References (40)

1. Greenfield DS, Liebmann JM, Ritch R, et al. Visual field and intraocular pressure asymmetry in the low-pressure glaucoma treatment study. Ophthalmology. 2007;114:460-465.
2. Gugleta K, Orgül S, Flammer J. Asymmetry in intraocular pressure and retinal nerve fiber layer thickness in normal-tension glaucoma. Ophthalmologica. 1999;213:219-223.
3. Wang JC, Gazzard G, Foster PJ, et al. Interocular asymmetry of visual field defects in primary open angle glaucoma and primary angle-closure glaucoma. Eye. 2004;18:365-368.
4. Krupin T, Liebmann JM, Greenfield DS, et al. The Low-pressure Glaucoma Treatment Study (LoGTS) study design and baseline characteristics of enrolled patients. Ophthalmology. 2005;112: 376-385.
5. Wilhelm H, Wilhelm B. Clinical applications of pupillography. J Neuroophthalmol. 2003;23:42-49.
6. Chew SS, Cunnningham WJ, Gamble GD, et al. Retinal nerve fiber layer loss in glaucoma patients with a relative afferent pupillary defect. Invest Ophthalmol Vis Sci. 2010;51:5049-5053.
7. Levatin P. Pupillary escape in disease of the retina or optic nerve. Arch Ophthalmol. 1959;62:768-779.
8. Kerrison JB, Buchanan K, Rosenberg ML, et al. Quantification of optic nerve axon loss associated with a relative afferent pupillary defect in the monkey. Arch Ophthalmol. 2001;119: 1333-1341.
9. Kawasaki A, Moore P, Kardon RH. Variability of the relative afferent pupillary defect. Am J Ophthalmol. 1995;120:622-633.
10. Thompson HS, Corbett JJ, Cox TA. How to measure the relative afferent pupillary defect. Surv Ophthalmol. 1981;26: 39-42.
11. Skorkovskja K, Wilhelm H, Lüdtke H, et al. Relative afferent pupillary defect in glaucoma [in German]. Klin Monbl Augenheilkd. 2011;228:979-983.
12. Charalel RA, Lin HS, Singh K. Glaucoma screening using relative afferent pupillary defect [published online ahead of print January 13, 2013]. J Glaucoma. doi:10.1097/ IJG.0b013e31826a9742.
13. Lankaranian D, Altangerel U, Spaeth GL, et al. The usefulness of a new method of testing for a relative afferent pupillary defect in patients with ocular hypertension and glaucoma. Trans Am Ophthalmol Soc. 2005;103:200-207.
14. Wilhelm H, Peters T, Lüdtke H, et al. The prevalence of relative afferent pupillary defects in normal subjects. J Neurooph-thalmol. 2007;27:263-267.
15. Lowenstein O, Loewenfeld IE. Electronic pupillography. A new instrument and some clinical applications. Arch Oph-thalmol. 1958;59:352-363.
16. Jonas JB, Zach FM, Naumann GO. Quantitative pupillometry of relative afferent defects in glaucoma. Arch Ophthalmol. 1990; 108:479-480.
17. Thompson HS, Montague P, Cox TA, Corbett JJ. The relationship between visual acuity, pupillary defect, and visual field loss. Am J Ophthalmol. 1982;93:681-688.
18. Johnson LN, Hill RA, Bartholomew MJ. Correlation of afferent pupillary defect with visual field loss on automated perimetry. Ophthalmology. 1988;95:1649-1655.
19. Kardon RH, Haupert CL, Thompson HS. The relationship between static perimetry and the relative afferent pupillary defect. Am J Ophthalmol. 1993;115:351-356.
20. Bovino JA, Burton TC. Measurement of the relative afferent pupillary defect in retinal detachment. Am J Ophthalmol. 1980;90:19-21.
21. Folk JC, Thompson HS, Farmer SG, et al. Relative afferent pupillary defect in eyes with retinal detachment. Ophthalmic Surg. 1987;18:757-759.
22. Newsome DA, Milton RC, Gass JD. Afferent pupillary defect in macular degeneration. Am J Ophthalmol. 1981;92:396-402.
23. Harwerth RS, Wheat JL, Fredette MJ, Anderson DR. Linking structure and function in glaucoma. Prog Retin Eye Res. 2010; 29:249-271.
24. Medeiros FA, Lisboa R, Weinreb RN, et al. A combined index of structure and function for staging glaucomatous damage. Arch Ophthalmol. 2012;130:1107-1116.
25. Medeiros FA, Zangwill LM, Anderson DR, et al. Estimating the rate of retinal ganglion cell loss in glaucoma. Am J Ophthalmol. 2012;154:814-824.
26. Medeiros FA, Lisboa R, Weinreb RN, et al. Retinal ganglion cell count estimates associated with early development of visual field defects in glaucoma. Ophthalmology. 2013;120:736-744.
27. Sample PA, Girkin CA, Zangwill LM, et al. The African Descent and Glaucoma Evaluation Study (ADAGES): design and baseline data. Arch Ophthalmol. 2009;127:1136-1145.
28. Medeiros FA, Weinreb RN, Sample PA, et al. Validation of a predictive model to estimate the risk of conversion from ocular hypertension to glaucoma. Arch Ophthalmol. 2005; 123:1351-1360.
29. Medeiros FA, Vizzeri G, Zangwill LM, et al. Comparison of retinal nerve fiber layer and optic disc imaging for diagnosing glaucoma in patients suspected of having the disease. Ophthalmology. 2008;115:1340-1346.
30. Racette L, Liebmann JM, Girkin CA, et al. African Descent and Glaucoma Evaluation Study (ADAGES): III. Ancestry differences in visual function in healthy eyes. Arch Ophthalmol. 2010; 128:551-559.
31. Sarezky D, Krupin T, Cohen A, et al. Correlation between intereye difference in visual field mean deviation values and relative afferent pupillary response as measured by an automated pupillometer in subjects with glaucoma [published online ahead of print January 18, 2013]. J Glaucoma. doi:10.1097/IJG.0b013e31827b1522
32. Medeiros FA, Zangwill LM, Bowd C, et al. The structure and function relationship in glaucoma: implications for detection of progression and measurement of rates of change. Invest Ophthalmol Vis Sci. 2012;53:6939-6946.
33. Lagrèze WD, Kardon RH. Correlation of relative afferent pupillary defect and estimated retinal ganglion cell loss. Graefes Arch Clin Exp Ophthalmol. 1998;236:401-404.
34. Tatsumi Y, Nakamura M, Fujioka M, et al. Quantification of retinal nerve fiber layer thickness reduction associated with a relative afferent pupillary defect in asymmetric glaucoma. Br J Ophthalmology. 2007;91:633-637.
35. Chang DS, Boland MV, Arora KS, et al. Symmetry of the pupillary light reflex and its relationship to retinal nerve fiber layer thickness and visual field defect. Invest Ophthalmol Vis Sci. 2013;54:5596-5601.
36. Garway-Heath DF, Caprioli J, Fitzke FW, et al. Scaling the hill of vision: the physiological relationship between light sensitivity and ganglion cell numbers. Invest Ophthalmol Vis Sci. 2000; 41:1774-1782.
37. Chang DS, Xu L, Boland MV, Friedman DS. Accuracy of pupil assessment for the detection of glaucoma: a systematic review and meta-analysis. Ophthalmology. 2013;120:2217-2225.
38. Carle CF, Maddess T, James AC. Contraction anisocoria: segregation, summation, and saturation in the pupillary pathway. Invest Ophthalmol Vis Sci. 2011;52:2365-7231.
39. Kawasaki A, Kardon RH. Intrinsically photosensitive retinal ganglion cells. J Neuroophthalmol. 2007;27:195-204.
40. Kankipati L, Girkin CA, Gamlin PD. The post-illumination pupil response is reduced in glaucoma patients. Invest Ophthalmol Vis Sci. 2011;52:2287-2292.