Functional analysis of a breast cancer-associated FGFR2 single nucleotide polymorphism using zinc finger mediated genome editing

PLoS ONE

Volumn 8, Issue 11, 2013, Pages

  Robbez Masson, Luisa J ^a   Bödör, Csaba ^a   Jones, J Louise ^a   Hurst, Helen C ^a   Fitzgibbon, Jude ^a   Hart, Ian R ^a   Grose, Richard P ^a  

^a QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ESTROGEN RECEPTOR ALPHA; FIBROBLAST GROWTH FACTOR RECEPTOR 2; HEPATOCYTE NUCLEAR FACTOR 3ALPHA; TRANSCRIPTION FACTOR RUNX2;

ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CANCER RISK; CELL CYCLE PROGRESSION; CELL FUNCTION; CELL PROLIFERATION; CONTROLLED STUDY; FGFR2 GENE; GENE EXPRESSION; GENE LOCUS; GENETIC RISK; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; PROTEIN PROTEIN INTERACTION; RNA EDITING; SINGLE NUCLEOTIDE POLYMORPHISM;

ALLELES; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL PROLIFERATION; CLONE CELLS; ESTROGEN RECEPTOR ALPHA; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE ORDER; HAPLOTYPES; HEPATOCYTE NUCLEAR FACTOR 3-ALPHA; HETEROZYGOTE; HUMANS; INTRONS; MCF-7 CELLS; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTEIN BINDING; RECEPTOR, FIBROBLAST GROWTH FACTOR, TYPE 2; RNA EDITING; SIGNAL TRANSDUCTION; ZINC FINGERS;

EID: 84893174624     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0078839     Document Type: Article

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