Enteroviral infections and development of type 1 diabetes: The brothers karamazov within the CVBs

Diabetes

Volumn 63, Issue 2, 2014, Pages 384-386

  Dotta, Francesco ^a   Sebastiani, Guido ^b  

^a UNIVERSITY OF SIENA   (Italy)

^b Fondazione Umberto Di Mario ONLUS   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

NEUTRALIZING ANTIBODY;

COXSACKIE VIRUS B; CROSS PROTECTION; DISEASE ASSOCIATION; DISEASE COURSE; DISEASE PREDISPOSITION; ENTEROVIRUS; ENTEROVIRUS INFECTION; ENVIRONMENTAL FACTOR; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; NOTE; PRIORITY JOURNAL;

ANIMALS; ANTIBODIES, VIRAL; COXSACKIEVIRUS INFECTIONS; DIABETES MELLITUS, TYPE 1; ENTEROVIRUS B, HUMAN; ENTEROVIRUS INFECTIONS; FEMALE; HUMANS; INSULIN-SECRETING CELLS; MALE;

EID: 84893155387     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db13-1441     Document Type: Note

References (17)

1. Ziegler AG, Nepom GT. Prediction and pathogenesis in type 1 diabetes. Immunity 2010;32:468-478
2. Grieco FA, Vendrame F, Spagnuolo I, Dotta F. Innate immunity and the pathogenesis of type 1 diabetes. Semin Immunopathol 2011;33:57-66
3. Coppieters KT, Dotta F, Amirian N, et al. Demonstration of isletautoreactive CD8 T cells in insulitic lesions from recent onset and longterm type 1 diabetes patients. J Exp Med 2012;209:51-60
4. Okada H, Kuhn C, Feillet H, Bach JF. The 'hygiene hypothesis' for autoimmune and allergic diseases: an update. Clin Exp Immunol 2010;160:1-9
5. Spagnuolo I, Patti A, Sebastiani G, Nigi L, Dotta F. The case for virus-induced type 1 diabetes. Curr Opin Endocrinol Diabetes Obes 2013;20:292-298
6. Yeung WC, Rawlinson WD, Craig ME. Enterovirus infection and type 1 diabetes mellitus: systematic review and meta-analysis of observational molecular studies. BMJ 2011;342:d35
7. Roivainen M, Ylipaasto P, Savolainen C, Galama J, Hovi T, Otonkoski T. Functional impairment and killing of human beta cells by enteroviruses: the capacity is shared by a wide range of serotypes, but the extent is a characteristic of individual virus strains. Diabetologia 2002;45:693-702
8. Boettler T, von Herrath M. Protection against or triggering of type 1 diabetes? Different roles for viral infections. Expert Rev Clin Immunol 2011; 7:45-53
9. Oikarinen S, Tauriainen S, Hober D, et al.; VirDiab Study Group. Virus antibody survey in different European populations indicates risk association between coxsackievirus B1 and type 1 diabetes. Diabetes 2014;63:655-662
10. Laitinen OH, Honkanen H, Pakkanen O, et al. Coxsackievirus B1 is associated with induction of b-cell autoimmunity that portends type 1 diabetes. Diabetes 2014;63:446-455
11. Kemball CC, Harkins S, Whitmire JK, Flynn CT, Feuer R, Whitton JL. Coxsackievirus B3 inhibits antigen presentation in vivo, exerting a profound and selective effect on the MHC class I pathway. PLoS Pathog 2009;5: e1000618
12. Mukherjee A, Morosky SA, Delorme-Axford E, et al. The coxsackievirus B 3C protease cleaves MAVS and TRIF to attenuate host type I interferon and apoptotic signaling. PLoS Pathog 2011;7:e1001311
13. Grieco FA, Sebastiani G, Spagnuolo I, Patti A, Dotta F. Immunology in the clinic review series; focus on type 1 diabetes and viruses: how viral infections modulate beta cell function. Clin Exp Immunol 2012;168:24-29
14. Hindersson M, Orn A, Harris RA, Frisk G. Strains of coxsackie virus B4 differed in their ability to induce acute pancreatitis and the responses were negatively correlated to glucose tolerance. Arch Virol 2004;149:1985-2000
15. Dotta F, Censini S, van Halteren AG, et al. Coxsackie B4 virus infection of beta cells and natural killer cell insulitis in recent-onset type 1 diabetic patients. Proc Natl Acad Sci USA 2007;104:5115-5120
16. Roivainen M, Klingel K. Virus infections and type 1 diabetes risk. Curr Diab Rep 2010;10:350-356
17. Ghazarian L, Diana J, Simoni Y, Beaudoin L, Lehuen A. Prevention or acceleration of type 1 diabetes by viruses. Cell Mol Life Sci 2013;70:239-255