The possible role of mesenchymal stem cells therapy in the repair of experimentally induced colitis in male albino rats

International Journal of Stem Cells

Volumn 6, Issue 2, 2013, Pages 92-103

  Fawzy, Sohair Ahmed ^a   Abo Elnou, Rahma Kamal El din ^a   El Deeb, Dalia Fathy Abd El Maksoud ^a   Abd Elkader, Marwa Mohamed Yousry ^a  

^a CAIRO UNIVERSITY   (Egypt)

Author keywords

Acetic acid; Colitis; MSCs; PKH26; Rat colon

Indexed keywords

EID: 84893136015     PISSN: 20053606     EISSN: 20055447     Source Type: Journal    
DOI: 10.15283/ijsc.2013.6.2.92     Document Type: Article

References (40)

1. Herías MV, Koninkx JF, Vos JG, Huis in't Veld JH, van Dijk JE. Probiotic effects of Lactobacillus casei on DSS-induced ulcerative colitis in mice. Int J Food Microbiol 2005;103:143-155
2. Elson CO, Sartor RB, Tennyson GS, Riddell RH. Experimental models of inflammatory bowel disease. Gastroenterology 1995;109:1344-1367
3. Hagar HH, El-Medany A, El-Eter E, Arafa M. Ameliorative effect of pyrrolidinedithiocarbamate on acetic acid-induced colitis in rats. Eur J Pharmacol 2007;554:69-77
4. Grove JE, Bruscia E, Krause DS. Plasticity of bone marrow-derived stem cells. Stem Cells 2004;22:487-500
5. Matsumoto T, Okamoto R, Yajima T, Mori T, Okamoto S, Ikeda Y, Mukai M, Yamazaki M, Oshima S, Tsuchiya K, Nakamura T, Kanai T, Okano H, Inazawa J, Hibi T, Watanabe M. Increase of bone marrow-derived secretory lineage epithelial cells during regeneration in the human intestine. Gastroenterology 2005;128:1851-1867
6. Brittan M, Wright NA. Stem cell in gastrointestinal structure and neoplastic development. Gut 2004;53:899-910
7. Tanaka F, Tominaga K, Ochi M, Tanigawa T, Watanabe T, Fujiwara Y, Ohta K, Oshitani N, Higuchi K, Arakawa T. Exogenous administration of mesenchymal stem cells ameliorates dextran sulfate sodium-induced colitis via anti-inflammatory action in damaged tissue in rats. Life Sci 2008;83:771-779
8. Wei Y, Nie Y, Lai J, Wan YJ, Li Y. Comparison of the population capacity of hematopoietic and mesenchymal stem cells in experimental colitis rat model. Transplantation 2009;88:42-48
9. Le Blanc K, Ringdén O. Immunomodulation by mesenchymal stem cells and clinical experience. J Intern Med 2007;262:509-525
10. Aggarwal S, Pittenger MF. Human mesenchymal stem cells modulate allogeneic immune cell responses. Blood 2005;105:1815-1822
11. Harisa GE, Abo-Salem OM, El-Sayed el-SM, Taha EI, El-Halawany N. L-arginine augments the antioxidant effect of garlic against acetic acid-induced ulcerative colitis in rats. Pak J Pharm Sci 2009;22:373-380
12. Liang L, Dong C, Chen X, Fang Z, Xu J, Liu M, Zhang X, Gu DS, Wang D, Du W, Zhu D, Han ZC. Human umbilical cord mesenchymal stem cells ameliorate mice trinitrobenzene sulfonic acid (TNBS)-induced colitis. Cell Transplant 2011;20:1395-1408
13. Cho YB, Kim MS, Kang MJ, Shin HJ, Kim SH, Kim HC, Yun SH, Lee WY, Chun HK. Immunomodulatory Effects of Mesenchymal Stem Cells in a Murine Model of TNBSInduced Colitis. J Korean Surg Soc 2010;79:317-325
14. Millar AD, Rampton DS, Chander CL, Claxson AW, Blades S, Coumbe A, Panetta J, Morris CJ, Blake DR. Evaluating the antioxidant potential of new treatments for inflammatory bowel disease using a rat model of colitis. Gut 1996; 39:407-415
15. Alhadlaq A, Mao JJ. Mesenchymal stem cells: isolation and therapeutics. Stem Cells Dev 2004;13:436-448
16. Rochefort GY, Vaudin P, Bonnet N, Pages JC, Domenech J, Charbord P, Eder V. Influence of hypoxia on the domiciliation of mesenchymal stem cells after infusion into rats: possibilities of targeting pulmonary artery remodeling via cells therapies? Respir Res 2005;6:125.
17. Abdel Aziz MT, El Asmar MF, Atta HM, Mahfouz S, Fouad HH, Roshdy NK, Rashed LA, Sabry D, Hassouna AA, Taha FM. Efficacy of mesenchymal stem cells in suppression of hepatocarcinorigenesis in rats: possible role of Wnt signaling. J Exp Clin Cancer Res 2011;30:49
18. Kiernan JA. Histological and histochemical methods. In: theory and practice. London, New York & New Delhi: Arnold Publisher; 2001. 111-162
19. Bancroft JD, Gamble MN. Mucins. In: Theory Practice of Histological Technique. London: Churchill Livingstone; 2002. 177-183
20. Suvarna SK, Layton C, Bancroft JD. Connective and mesenchymal tissue with their stains. In: Bancroft's Theory and practice of histological techniques. Oxford: Churchill Livingstone Elsevier; 2012. 187-214
21. Zhang J, Zhi W, Tan M, Chen X, Li X, Deng L. An experimental study on rabbit bone marrow mesenchymal stem cells double-labeled by PKH26 and 5-bromo-2'-deoxyuridine in vitro and application in cardiac patch. Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 2010;24:828-833
22. Emsley R, Dunn G, White IR. Mediation and moderation of treatment effects in randomised controlled trials of complex interventions. Stat Methods Med Res 2010;19:237-270
23. Soliman NBE, Kalleny NK, Abd El Samad AA. Effect of Omega-3 versus Omega-6 fatty acids on induced ulcerative colitis in male albino rat. light and electron microscopic study. Egypt J Histol 2010;33:620-634
24. Nakhai LA, Mohammadirad A, Yasa N, Minaie B, Nikfar S, Ghazanfari G, Zamani MJ, Dehghan G, Jamshidi H, Boushehri VS, Khorasani R, Abdollahi M. Benefits of zataria multiflora boiss in experimental model of mouse inflammatory bowel disease. Evid Based Complement Alternat Med 2007;4:43-50
25. Kumar V, Abbas AK, Aster JC, Robbins SL. Cell Injury, Cell Death and Adaptations, Inflammation and Repair. In: Robbins Basic Pathology. Philadelphia, London: Saunders; 2012. 1-26, 29-74
26. Tanaka H, Arimura Y, Yabana T, Goto A, Hosokawa M, Nagaishi K, Yamashita K, Yamamoto H, Sasaki Y, Fujimiya M, Imai K, Shinomura Y. Myogenic lineage differentiated mesenchymal stem cells enhance recovery from dextran sulfate sodium-induced colitis in the rat. J Gastroenterol 2011;46:143-152
27. Rubin R, Strayer DS. Inflammation. In: Rubin's Pathology: Clinicopathologic Foundations of Medicine. Philadelphia: Lippincott Williams & Wilkins; 2012. 47-82
28. Hayashi Y, Tsuji S, Tsujii M, Nishida T, Ishii S, Iijima H, Nakamura T, Eguchi H, Miyoshi E, Hayashi N, Kawano S. Topical implantation of mesenchymal stem cells has beneficial effects on healing of experimental colitis in rats. J Pharmacol Exp Ther 2008;326:523-531
29. Rampton DS. Unravelling the pathogenesis of inflammatory bowel disease. In: Inflammatory bowel disease: clinical diagnosis and management. London: Martin Dunitz; 2000.35-50
30. Komori M, Tsuji S, Tsujii M, Murata H, Iijima H, Yasumaru M, Nishida T, Irie T, Kawano S, Hori M. Involvement of bone marrow-derived cells in healing of experimental colitis in rats. Wound Repair Regen 2005;13:109-118
31. Valcz G, Krenócs T, Sipos F, Leiszter K, Tóth K, Balogh Z, Csizmadia A, Muzes G, Molnár B, Tulassay Z. The role of the bone marrow derived mesenchymal stem cells in colonic epithelial regeneration. Pathol Oncol Res 2011;17:11-6
32. Newman RE, Yoo D, LeRoux MA, Danilkovitch-Miagkova A. Treatment of inflammatory diseases with mesenchymal stem cells. Inflamm Allergy Drug Targets 2009;8:110-123
33. Andoh A, Bamba S, Fujiyama Y, Brittan M, Wright NA. Colonic subepithelial myofibroblasts in mucosal inflammation and repair: contribution of bone marrow-derived stem cells to the gut regenerative response. J Gastroenterol 2005; 40:1089-1099
34. Linden SK, Florin TH, McGuckin MA. Mucin dynamics in intestinal bacterial infection. PLoS One 2008;3:3952-3965
35. Micallef L, Vedrenne N, Billet F, Coulomb B, Darby IA, Desmoulière A. The myofibroblast, multiple origins for major roles in normal and pathological tissue repair. Fibrogenesis Tissue Repair 2012;5 Suppl 1:S5
36. Castelo-Branco MT, Soares ID, Lopes DV, Buongusto F, Martinusso CA, do Rosario A Jr, Souza SA, Gutfilen B, Fonseca LM, Elia C, Madi K, Schanaider A, Rossi MI, Souza HS. Intraperitoneal but not intravenous cryopreserved mesenchymal stromal cells home to the inflamed colon and ameliorate experimental colitis. PLoS One 2012; 7:e33360
37. Suga H, Eto H, Shigeura T, Inoue K, Aoi N, Kato H, Nishimura S, Manabe I, Gonda K, Yoshimura K. IFATS collection: Fibroblast growth factor-2-induced hepatocyte growth factor secretion by adipose-derived stromal cells inhibits postinjury fibrogenesis through a c-Jun N-terminal kinase-dependent mechanism. Stem Cells 2009;27:238-249
38. Elkhafif N, El Baz H, Hammam O, Hassan S, Salah F, Mansour W, Mansy S, Yehia H, Zaki A, Magdy R. CD133(+) human umbilical cord blood stem cells enhance angiogenesis in experimental chronic hepatic fibrosis. APMIS 2011;119:66-75
39. Okamoto R, Watanabe M. Cellular and molecular mechanisms of the epithelial repair in IBD. Dig Dis Sci 2005;50 Suppl 1:S34-38
40. Brittan M, Alison MR, Schier S, Wright NA. Bone marrow stem cell-mediated regeneration in IBD: where do we go from here? Gastroenterology 2007;132:1171-1173