Sex differences in rates of obesity in bipolar disorder: Postulated mechanisms

Bipolar Disorders

Volumn 16, Issue 1, 2014, Pages 83-92

  Baskaran, Anusha ^a,b   Cha, Danielle S ^b,c   Powell, Alissa M ^b,c   Jalil, Dalya ^b   Mcintyre, Roger S ^b,c  

^a QUEEN S UNIVERSITY   (Canada)

^b UNIVERSITY HEALTH NETWORK   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

Author keywords

Bipolar disorder; Female; Metabolic syndrome; Obesity; Women

Indexed keywords

ABDOMINAL OBESITY; BIPOLAR DISORDER; CARDIOVASCULAR DISEASE; COMORBIDITY; DEPRESSION; DIABETES MELLITUS; DYSLIPIDEMIA; HUMAN; HYPERTENSION; LIFESTYLE; METABOLIC SYNDROME X; OBESITY; POPULATION; PRIORITY JOURNAL; REVIEW; SEASONAL VARIATION; SEX DIFFERENCE; STANDARDIZED MORTALITY RATIO;

BIPOLAR DISORDER; FEMALE; METABOLIC SYNDROME; OBESITY; WOMEN;

BIPOLAR DISORDER; FEMALE; HUMANS; LIFE CHANGE EVENTS; LIFE STYLE; MALE; OBESITY; PUBMED; REPRODUCTION; SEX CHARACTERISTICS;

EID: 84893130191     PISSN: 13985647     EISSN: 13995618     Source Type: Journal    
DOI: 10.1111/bdi.12141     Document Type: Review

References (92)

1. Judd LL, Paulus MP, Wells KB, Rapaport MH. Socioeconomic burden of subsyndromal depressive symptoms and major depression in a sample of the general population. Am J Psychiatry 1996; 153: 1411-1417.
2. Collins PY, Patel V, Joestl SS et al. Grand challenges in global mental health. Nature 2011; 475: 27-30.
3. Taylor V, Macqueen G. Associations between bipolar disorder and metabolic syndrome: a review. J Clin Psychiatry 2006; 67: 1034-1041.
4. Kupfer DJ. The increasing medical burden in bipolar disorder. JAMA 2005; 293: 2528-2530.
5. Fiedorowicz JG, Palagummi NM, Forman-Hoffman VL, Miller DD, Haynes WG. Elevated prevalence of obesity, metabolic syndrome, and cardiovascular risk factors in bipolar disorder. Ann Clin Psychiatry 2008; 20: 131-137.
6. Ford ES. Prevalence of the metabolic syndrome defined by the International Diabetes Federation among adults in the U.S. Diabetes Care 2005; 28: 2745-2749.
7. McIntyre RS, Danilewitz M, Liauw SS et al. Bipolar disorder and metabolic syndrome: an international perspective. J Affect Disord 2010; 126: 366-387.
8. Dinan T, Thakore J, Citrome L et al. Metabolic and lifestyle issues and severe mental illness - new connections to well-being? J Psychopharmacol 2005; 19 (Suppl. 6): 188-222.
9. McIntyre RS, Konarski JZ, Misener VL, Kennedy SH. Bipolar disorder and diabetes mellitus: epidemiology, etiology, and treatment implications. Ann Clin Psychiatry 2005; 17: 83-93.
10. Goldstein BI, Liu S-M, Zivkovic N, Schaffer A, Chien L-C, Blanco C. The burden of obesity among adults with bipolar disorder in the United States. Bipolar Disord 2011; 13: 387-395.
11. Garcia-Portilla MP, Saiz PA, Benabarre A et al. The prevalence of metabolic syndrome in patients with bipolar disorder. J Affect Disord 2008; 106: 197-201.
12. Osby U, Brandt L, Correia N, Ekbom A, Sparen P. Excess mortality in bipolar and unipolar disorder in Sweden. Arch Gen Psychiatry 2001; 58: 844-850.
13. Kenna HA, Jiang B, Rasgon NL. Reproductive and metabolic abnormalities associated with bipolar disorder and its treatment. Harv Rev Psychiatry 2009; 17: 138-146.
14. Tirupati S, Chua LE. Obesity and metabolic syndrome in a psychiatric rehabilitation service. Aust N Z J Psychiatry 2007; 41: 606-610.
15. van Winkel R, De Hert M, Van Eyck D et al. Prevalence of diabetes and the metabolic syndrome in a sample of patients with bipolar disorder. Bipolar Disord 2008; 10: 342-348.
16. Arnold LM. Gender differences in bipolar disorder. Psychiatr Clin North Am 2003; 26: 595-620.
17. Barnes C, Mitchell P. Considerations in the management of bipolar disorder in women. Aust N Z J Psychiatry 2005; 39: 662-673.
18. Sit D. Women and bipolar disorder across the life span. J Am Med Womens Assoc 2004; 59: 91-100.
19. Vega P, Barbeito S, de Azua SR et al. Bipolar disorder differences between genders: special considerations for women. Womens Health 2011; 7: 663-674.
20. Sutin AR, Zonderman AB. Depressive symptoms are associated with weight gain among women. Psychol Med 2012; 42: 2351-2360.
21. Bond DJ, Kauer-Sant'Anna M, Lam RW, Yatham LN. Weight gain, obesity, and metabolic indices following a first manic episode: prospective 12-month data from the Systematic Treatment Optimization Program for Early Mania (STOP-EM). J Affect Disord 2010; 124: 108-117.
22. Cassidy F, Carroll BJ. Hypocholesterolemia during mixed manic episodes. Eur Arch Psychiatry Clin Neurosci 2002; 252: 110-114.
23. Pacifico L, Anania C, Ferraro F, Andreoli GM, Chiesa C. Thyroid function in childhood obesity and metabolic comorbidity. Clin Chim Acta 2012; 413: 396-405.
24. Reinehr T. Obesity and thyroid function. Mol Cell Endocrinol 2010; 316: 165-171.
25. Frye MA, Yatham L, Ketter TA et al. Depressive relapse during lithium treatment associated with increased serum thyroid-stimulating hormone: results from two placebo-controlled bipolar I maintenance studies. Acta Psychiatr Scand 2009; 120: 10-13.
26. Vo M, Ainalem A, Qiu C, Peterlin BL, Aurora SK, Williams MA. Body mass index and adult weight gain among reproductive age women with migraine. Headache 2011; 51: 559-569.
27. Lipton RB, Stewart WF, Diamond S, Diamond ML, Reed M. Prevalence and burden of migraine in the United States: data from the American Migraine Study II. Headache 2001; 41: 646-657.
28. Oedegaard KJ, Dilsaver SC, Hundal O et al. Are migraine and bipolar disorders comorbid phenomena?: findings from a pharmacoepidemiological study using the Norwegian Prescription Database. J Clin Psychopharmacol 2011; 31: 734-739.
29. McIntyre RS, Konarski JZ, Wilkins K, Bouffard B, Soczynska JK, Kennedy SH. The prevalence and impact of migraine headache in bipolar disorder: results from the Canadian Community Health Survey. Headache 2006; 46: 973-982.
30. Ortiz-Domínguez A, Hernández ME, Berlanga C et al. Immune variations in bipolar disorder: phasic differences. Bipolar Disord 2007; 9: 596-602.
31. Baskin SM, Smitherman TA. Migraine and psychiatric disorders: comorbidities, mechanisms, and clinical applications. Neurol Sci 2009; 30 (Suppl. 1): S61-S65.
32. Diflorio A, Jones I. Is sex important? Gender differences in bipolar disorder. Int Rev Psychiatry 2010; 22: 437-452.
33. Freeman MP, Gelenberg AJ. Bipolar disorder in women: reproductive events and treatment considerations. Acta Psychiatr Scand 2005; 112: 88-96.
34. Hartlage SA, Arduino KE, Gehlert S. Premenstrual dysphoric disorder and risk for major depressive disorder: a preliminary study. J Clin Psychol 2001; 57: 1571-1578.
35. Viguera AC, Nonacs R, Cohen LS, Tondo L, Murray A, Baldessarini RJ. Risk of recurrence of bipolar disorder in pregnant and nonpregnant women after discontinuing lithium maintenance. Am J Psychiatry 2000; 157: 179-184.
36. Wieck A, Davies RA, Hirst AD et al. Menstrual cycle effects on hypothalamic dopamine receptor function in women with a history of puerperal bipolar disorder. J Psychopharmacol 2003; 17: 204-209.
37. Marks MN, Wieck A, Checkley SA, Kumar R. Contribution of psychological and social factors to psychotic and non-psychotic relapse after childbirth in women with previous histories of affective disorder. J Affect Disord 1992; 24: 253-263.
38. Chandra PS. Post-ovariectomy and oestrogen therapy related recurrence of oestrogen withdrawal associated psychosis. Acta Psychiatr Scand 2002; 106: 76-77.
39. Mahe V, Dumaine A. Oestrogen withdrawal associated psychoses. Acta Psychiatr Scand 2001; 104: 323-331.
40. Yonkers KA, Vigod S, Ross LE. Diagnosis, pathophysiology, and management of mood disorders in pregnant and postpartum women. Obstet Gynecol 2011; 117: 961-977.
41. Bastian LA, West NA, Corcoran C, Munger RG. Number of children and the risk of obesity in older women. Prev Med 2005; 40: 99-104.
42. Harris HE, Ellison GT, Clement S. Do the psychosocial and behavioral changes that accompany motherhood influence the impact of pregnancy on long-term weight gain? J Psychosom Obstet Gynaecol 1999; 20: 65-79.
43. Avis NE, Brambilla D, McKinlay SM, Vass K. A longitudinal analysis of the association between menopause and depression. Results from the Massachusetts Women's Health Study. Ann Epidemiol 1994; 4: 214-220.
44. Hunter MS. Emotional well-being, sexual behaviour and hormone replacement therapy. Maturitas 1990; 12: 299-314.
45. Freeman MP, Smith KW, Freeman SA et al. The impact of reproductive events on the course of bipolar disorder in women. J Clin Psychiatry 2002; 63: 284-287.
46. Freeman EW, Sammel MD, Lin H, Nelson DB. Associations of hormones and menopausal status with depressed mood in women with no history of depression. Arch Gen Psychiatry 2006; 63: 375-382.
47. Huerta R, Mena A, Malacara JM, de Leon JD. Symptoms at the menopausal and premenopausal years: their relationship with insulin, glucose, cortisol, FSH, prolactin, obesity and attitudes towards sexuality. Psychoneuroendocrinology 1995; 20: 851-864.
48. Marsh WK, Ketter TA, Rasgon NL. Increased depressive symptoms in menopausal age women with bipolar disorder: age and gender comparison. J Psychiatr Res 2009; 43: 798-802.
49. Joffe H, Cohen LS, Suppes T et al. Valproate is associated with new-onset oligoamenorrhea with hyperandrogenism in women with bipolar disorder. Biol Psychiatry 2006; 59: 1078-1086.
50. McIntyre RS, Mancini DA, McCann S, Srinivasan J, Kennedy SH. Valproate, bipolar disorder and polycystic ovarian syndrome. Bipolar Disord 2003; 5: 28-35.
51. Stephenson T, Stewart G. PCOS: clinical presentation guides treatment of this multifaceted disease. JAAPA 2010; 23: 20-24.
52. Banaszewska B, Duleba AJ, Spaczynski RZ, Pawelczyk L. Lipids in polycystic ovary syndrome: role of hyperinsulinemia and effects of metformin. Am J Obstet Gynecol 2006; 194: 1266-1272.
53. Lo JC, Feigenbaum SL, Yang J, Pressman AR, Selby JV, Go AS. Epidemiology and adverse cardiovascular risk profile of diagnosed polycystic ovary syndrome. J Clin Endocrinol Metab 2006; 91: 1357-1363.
54. Knochenhauer ES, Key TJ, Kahsar-Miller M, Waggoner W, Boots LR, Azziz R. Prevalence of the polycystic ovary syndrome in unselected black and white women of the southeastern United States: a prospective study. J Clin Endocrinol Metab 1998; 83: 3078-3082.
55. Apridonidze T, Essah PA, Iuorno MJ, Nestler JE. Prevalence and characteristics of the metabolic syndrome in women with polycystic ovary syndrome. J Clin Endocrinol Metab 2005; 90: 1929-1935.
56. Barfield E, Liu YH, Kessler M, Pawelczak M, David R, Shah B. The prevalence of abnormal liver enzymes and metabolic syndrome in obese adolescent females with polycystic ovary syndrome. J Pediatr Adolesc Gynecol 2009; 22: 318-322.
57. Daruy-Filho L, Brietzke E, Lafer B, Grassi-Oliveira R. Childhood maltreatment and clinical outcomes of bipolar disorder. Acta Psychiatr Scand 2011; 124: 427-434.
58. Post RM, Leverich GS, Xing G, Weiss RB. Developmental vulnerabilities to the onset and course of bipolar disorder. Dev Psychopathol 2001; 13: 581-598.
59. Hyun M, Friedman SD, Dunner DL. Relationship of childhood physical and sexual abuse to adult bipolar disorder. Bipolar Disord 2000; 2: 131-135.
60. Conus P, Cotton S, Schimmelmann BG et al. Pretreatment and outcome correlates of past sexual and physical trauma in 118 bipolar I disorder patients with a first episode of psychotic mania. Bipolar Disord 2010; 12: 244-252.
61. Whitaker RC, Wright JA, Pepe MS, Seidel KD, Dietz WH. Predicting obesity in young adulthood from childhood and parental obesity. N Engl J Med 1997; 337: 869-873.
62. Pine DS, Goldstein RB, Wolk S, Weissman MM. The association between childhood depression and adulthood body mass index. Pediatrics 2001; 107: 1049-1056.
63. Felitti VJ, Anda RF, Nordenberg D et al. Relationship of childhood abuse and household dysfunction to many of the leading causes of death in adults. The Adverse Childhood Experiences (ACE) Study. Am J Prev Med 1998; 14: 245-258.
64. Alciati A, Gesuele F, Rizzi A, Sarzi-Puttini P, Foschi D. Childhood parental loss and bipolar spectrum in obese bariatric surgery candidates. Int J Psychiatry Med 2011; 41: 155-171.
65. Holt RI, Peveler RC. Obesity, serious mental illness and antipsychotic drugs. Diabetes Obes Metab 2009; 11: 665-679.
66. Lee HA, Lee WK, Kong KA et al. The effect of eating behavior on being overweight or obese during preadolescence. J Prev Med Public Health 2011; 44: 226-233.
67. McElroy SL, Kotwal R, Malhotra S, Nelson EB, Keck PE, Nemeroff CB. Are mood disorders and obesity related? A review for the mental health professional. J Clin Psychiatry 2004; 65: 634-651.
68. Elmslie JL, Mann JI, Silverstone JT, Williams SM, Romans SE. Determinants of overweight and obesity in patients with bipolar disorder. J Clin Psychiatry 2001; 62: 486-491.
69. Pepino MY, Mennella JA. Habituation to the pleasure elicited by sweetness in lean and obese women. Appetite 2012; 58: 800-805.
70. Epstein LH, Temple JL, Roemmich JN, Bouton ME. Habituation as a determinant of human food intake. Psychol Rev 2009; 116: 384-407.
71. McLaren L, Godley J, MacNairn IA. Social class, gender, and time use: implications for the social determinants of body weight? Health Rep 2009; 20: 65-73.
72. Kimokoti RW, Newby PK, Gona P et al. Diet quality, physical activity, smoking status, and weight fluctuation are associated with weight change in women and men. J Nutr 2010; 140: 1287-1293.
73. Amianto F, Lavagnino L, Leombruni P, Gastaldi F, Daga GA, Fassino S. Hypomania across the binge eating spectrum. A study on hypomanic symptoms in full criteria and sub-threshold binge eating subjects. J Affect Disord 2011; 133: 580-583.
74. Javaras KN, Pope HG, Lalonde JK et al. Co-occurrence of binge eating disorder with psychiatric and medical disorders. J Clin Psychiatry 2008; 69: 266-273.
75. Kleinman NL, Brook RA, Rajagopalan K, Gardner HH, Brizee TJ, Smeeding JE. Lost time, absence costs, and reduced productivity output for employees with bipolar disorder. J Occup Environ Med 2005; 47: 1117-1124.
76. Hruschka DJ. Do economic constraints on food choice make people fat? A critical review of two hypotheses for the poverty-obesity paradox. Am J Hum Biol 2012; 24: 277-285.
77. Burkert NT, Freidl W, Muckenhuber J, Stronegger WJ, Rasky E. Self-perceived health, quality of life, and health-related behavior in obesity: is social status a mediator? Wien Klin Wochenschr 2012; 124: 271-275.
78. Chapman BP, Fiscella K, Duberstein P, Kawachi I, Coletta M. Can the influence of childhood socioeconomic status on men's and women's adult body mass be explained by adult socioeconomic status or personality? Findings from a national sample. Health Psychol 2009; 28: 419-427.
79. Brown SL, Salive ME, Guralnik JM, Pahor M, Chapman DP, Blazer D. Antidepressant use in the elderly: association with demographic characteristics, health-related factors, and health care utilization. J Clin Epidemiol 1995; 48: 445-453.
80. Wang PS, Berglund P, Kessler RC. Recent care of common mental disorders in the United States: prevalence and conformance with evidence-based recommendations. J Gen Intern Med 2000; 15: 284-292.
81. Williams JB, Spitzer RL, Linzer M et al. Gender differences in depression in primary care. Am J Obstet Gynecol 1995; 173: 654-659.
82. Malhi GS, Tanious M, Das P, Berk M. The science and practice of lithium therapy. Aust N Z J Psychiatry 2012; 46: 192-211.
83. Sathya A, Radhika R, Mahadevan S, Sriram U. Mania as a presentation of primary hypothyroidism. Singapore Med J 2009; 50: e65-e67.
84. Stowell CP, Barnhill JW. Acute mania in the setting of severe hypothyroidism. Psychosomatics 2005; 46: 259-261.
85. Bowden CL. Valproate. Bipolar Disord 2003; 5: 189-202.
86. Joffe H, Cohen LS, Suppes T et al. Longitudinal follow-up of reproductive and metabolic features of valproate-associated polycystic ovarian syndrome features: a preliminary report. Biol Psychiatry 2006; 60: 1378-1381.
87. Andreazza AC, Kapczinski F, Kauer-Sant'Anna M et al. 3-Nitrotyrosine and glutathione antioxidant system in patients in the early and late stages of bipolar disorder. J Psychiatry Neurosci 2009; 34: 263-271.
88. Covell NH, Weissman EM, Essock SM. Weight gain with clozapine compared to first generation antipsychotic medications. Schizophr Bull 2004; 30: 229-240.
89. Wu RR, Zhao JP, Zhai JG, Guo XF, Guo WB. Sex difference in effects of typical and atypical antipsychotics on glucose-insulin homeostasis and lipid metabolism in first-episode schizophrenia. J Clin Psychopharmacol 2007; 27: 374-379.
90. Andersen SW, Clemow DB, Corya SA. Long-term weight gain in patients treated with open-label olanzapine in combination with fluoxetine for major depressive disorder. J Clin Psychiatry 2005; 66: 1468-1476.
91. Fava M, Amsterdam JD, Deltito JA, Salzman C, Schwaller M, Dunner DL. A double-blind study of paroxetine, fluoxetine, and placebo in outpatients with major depression. Ann Clin Psychiatry 1998; 10: 145-150.
92. Sussman N, Ginsberg DL, Bikoff J. Effects of nefazodone on body weight: a pooled analysis of selective serotonin reuptake inhibitor- and imipramine-controlled trials. J Clin Psychiatry 2001; 62: 256-260.