Stem cell-based bone repair

American Journal of Stem Cells

Volumn 1, Issue 2, 2012, Pages 106-113

  Fei, Yurong ^a   Xu, Ren He ^a   Hurley, Marja M ^a  

^a UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

Author keywords

And bone marrow stromal stem cells; Bone repair; Embryonic stem cells

Indexed keywords

5' NUCLEOTIDASE; ACTIVATING TRANSCRIPTION FACTOR 4; CD11B ANTIGEN; CD45 ANTIGEN; COLLAGEN TYPE 1; DEXAMETHASONE; GLYCOPHORIN A; OSTEOCALCIN; PEPTIDES AND PROTEINS; STRO 1 PROTEIN; TRANSCRIPTION FACTOR OSTERIX; TRANSCRIPTION FACTOR RUNX2; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1;

BONE REGENERATION; BONE REMODELING; CARCINOGENICITY; CELL DIFFERENTIATION; CELL RENEWAL; EMBRYONIC STEM CELL; HEMATOPOIETIC STEM CELL; HUMAN; IMMUNE RESPONSE; MESENCHYMAL STEM CELL; NONHUMAN; OSSIFICATION; OSTEOBLAST; OSTEOLYSIS; PLURIPOTENT STEM CELL; REVIEW; STEM CELL TRANSPLANTATION;

EID: 84893118072     PISSN: None     EISSN: 21604150     Source Type: Journal    
DOI: None     Document Type: Review

References (62)

1. Slater BJ, Kwan MD, Gupta DM, Panetta NJ, and Longaker MT. Mesenchymal cells for skeletal tissue engineering. Expert Opinion on Biological Therapy 2008; 8: 885-893.
2. Verettas DA, Galanis B, Kazakos K, Hatziyiannakis A and Kotsios E. Fractures of the proximal part of the femur in patients under 50 years of age. Injury 2002; 33: 41-45.
3. Meijer GJ, de Bruijn JD, Koole R and van Blitterswijk CA. Cell-based bone tissue engineering. PLoS Medicine 2007; 4: e9.
4. Kneser U, Schaefer DJ, Polykandriotis E and Horch RE. Tissue engineering of bone: the reconstructive surgeon's point of view. Journal of Cellular and Molecular Medicine 2006; 10: 7-19.
5. Marolt D, Knezevic M and Novakovic GV. Bone tissue engineering with human stem cells. Stem Cell Research & Therapy 2010; 4: 10-20.
6. Harada, S and Rodan, GA., Control of osteoblast function and regulation of bone mass. Nature 2003; 423: 349-355.
7. Raisz LG. Pathogenesis of osteoporosis: concepts, conflicts, and prospects. Journal Clinical Investigation 2005; 115: 3318-3325.
8. Karsenty G. Transcriptional control of skeletogenesis. Annual Review of Genomics and Hu man Genetics 2008; 9: 183-196.
9. Baron R. General Principles of Bone Biology. Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism, ed. by Murray J. Favus. The American Society for Bone and Mineral Research, Washington, D.C., 2003; 1-8.
10. Ornitz DM, Marie PJ. FGF signaling pathways in endochondral and intramembranous bone development and human genetic disease. Genes and Development 2002; 16: 1446-1465.
11. Thomson JA, Itskovitz-Eldor J, Shapiro SS, Waknitz MA, Swiergiel JJ, Marshall VS, Jones JM. Embryonic Stem Cell Lines Derived from Human Blastocysts. Science 1998; 282: 1145-1147.
12. Martin, GR. Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells. Proceedings of the National Academy of Sciences of the United States 1981; 78: 7634-7638.
13. Evans MJ and Kaufman MH. Establishment in culture of pluripotential cells from mouse embryos. Nature 1981; 292: 154-156.
14. Itskovitz-Eldor J, Schuldiner M, Karsenti D, Eden A, Yanuka O, Amit M, Soreq H, Benvenisty N. Differentiation of human embryonic stem cells into embryoid bodies compromising the three embryonic germ layers. Molecular Medicine 2000; 6: 88-95.
15. Buttery LD, Bourne S, Xynos JD, Wood H, Hughes FJ, Hughes SP, Episkopou V, Polak JM. Differentiation of osteoblasts and in vitro bone formation from murine embryonic stem cells. Tissue Engineering 2001; 7: 89-99.
16. Bielby RC, Boccaccini AR, Polak JM, Buttery LD. In vitro differentiation and in vivo mineralization of osteogenic cells derived from human embryonic stem cells. Tissue Engineering 2004; 10: 1518-25.
17. Jukes JM, Both SK, Leusink A, Sterk LM, van Blitterswijk CA, de Boer J. Endochondral bone tissue engineering using embryonic stem cells. Proceedings of the National Academy of Sciences of the United States 2008; 105: 6840-6845.
18. Arpornmaeklong P, Brown SE, Wang Z, Krebsbach PH. Phenotypic characterization, osteoblastic differentiation, and bone regeneration capacity of human embryonic stem cellderived mesenchymal stem cells. Stem Cells and Development 2009; 18: 955-968.
19. Choo A, Lim SK. Derivation of mesenchymal stem cells from human embryonic stem cells. Methods in Molecular Biology 2011; 690: 175-182.
20. Brown SE, Tong W, Krebsbach PH. The derivation of mesenchymal stem cells from human embryonic stem cells. Cells Tissues Organs 2009; 189: 256-260.
21. Olivier EN, Rybicki AC, Bouhassira EE. Differentiation of Human Embryonic Stem Cells into Bipotent Mesenchymal Stem Cells. Stem Cells 2006; 24: 1914-1922.
22. Tremoleda JL, Forsyth NR, Khan NS, Wojtacha D, Christodoulou I, Tye BJ, Racey SN, Collishaw S, Sottile V, Thomson AJ, Simpson AH, Noble BS, McWhir J. Bone tissue formation from human embryonic stem cells in vivo. Cloning Stem Cells 2008; 10: 119-132.
23. Both SK, van Apeldoorn AA, Jukes JM, Englund MC, Hyllner J, van Blitterswijk CA, de Boer J. Differential bone-forming capacity of osteogenic cells from either embryonic stem cells or bone marrow-derived mesenchymal stem cells. Journal of Tissue Engineering and Regenerative Medicine 2011; 5: 180-190.
24. Polak DJ. Regenerative medicine. Opportunities and challenges: a brief overview. Journal of the Royal Society Interface 2010; 6: S777-781.
25. Takahashi K, Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 2006; 126: 663-676.
26. Takahashi K, Tanabe K, Ohnuki M, Narita M, Ichisaka T, Tomoda K, Yamanaka S. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 2007; 131: 861-872.
27. Yu J, Vodyanik MA, Smuga-Otto K, Antosiewicz-Bourget J, Frane JL, Tian S, Nie J, Jonsdottir GA, Ruotti V, Stewart R, Slukvin II, Thomson JA. Induced pluripotent stem cell lines derived from human somatic cells. Science 2007; 318: 1917-1920.
28. Zhou H, Wu S, Joo JY, Zhu S, Han DW, Lin T, Trauger S, Bien G, Yao S, Zhu Y, Siuzdak G, Schöler HR, Duan L, Ding S., Generation of induced pluripotent stem cells using recombinant proteins. Cell Stem Cell 2009; 4: 381-384.
29. Park IH, Zhao R, West JA, Yabuuchi A, Huo H, Ince TA, Lerou PH, Lensch MW, Daley GQ. Reprogramming of human somatic cells to pluripotency with defined factors. Nature 2008; 451: 141-146.
30. Kooreman NG, Wu JC. Tumorigenicity of pluripotent stem cells: biological insights from molecular imaging. Journal of the Royal Society Interface 2010; 7: S753-763.
31. Pomper MG, Hammond H, Yu X, Ye Z, Foss CA, Lin DD, Fox JJ, Cheng L. Serial imaging of human embryonic stem-cell engraftment and teratoma formation in live mouse models. Cell Research 2009; 19: 370-379.
32. Pittenger MF, Mackay AM, Beck SC, Jaiswal RK, Douglas R, Mosca JD, Moorman MA, Simonetti DW, Craig S, Marshak DR. Multilineage potential of adult human mesenchymal stem cells. Science 1999; 284: 143-147.
33. Friedenstein AJ, Chailakhyan RK, Gerasimov UV. Bone marrow osteogenic stem cells: in vitro cultivation and transplantation in diffusion chambers. Cell & Tissue Kinetics 1987; 20: 263-272.
34. Quarto R, Mastrogiacomo M, Cancedda R, Kutepov SM, Mukhachev V, Lavroukov A, Kon E, Marcacci M. Repair of large bone defects with the use of autologous bone marrow stromal cells. The New Englang Journal of Medicine 2001; 344: 385-386.
35. Abdallah BM, Kassem M. The use of mesenchymal (skeletal) stem cells for treatment of degenerative diseases: current status and future perspectives. Journal of Cell Physiology 2009; 218: 9-12.
36. Abdallah BM, Haack-Sørensen M, Burns JS, Elsnab B, Jakob F, Hokland P, Kassem M. Maintenance of differentiation potential of human bone marrow mesenchymal stem cells immortalized by human telomerase reverse transcriptase gene despite of extensive proliferation. Biochemical and Biophysical Research Communications 2005; 326: 527-538.
37. Post S, Abdallah BM, Bentzon JF, Kassem M. Demonstration of the presence of independent pre-osteoblastic and pre-adipocytic cell populations in bone marrow-derived mesenchymal stem cells. Bone 2008; 43: 32-39.
38. Kolf CM, Cho E, Tuan RS. Mesenchymal stromal cells. Biology of adult mesenchymal stem cells: regulation of niche, self-renewal and differentiation. Arthritis Research & Therapy 2007; 9: 204-214.
39. Dennis JE, Carbillet JP, Caplan AI, Charbord P. The STRO-1+ marrow cell population is multipotential. Cells Tissues Organs 2002; 170: 73-82.
40. Lin G, Liu G, Banie L, Wang G, Ning H, Lue TF, Lin CS. Tissue distribution of mesenchymal stem cell marker Stro-1. Stem Cells and Development 2011; 20: 1747-1752.
41. Ramasamy R, Tong CK, Seow HF, Vidyadaran S, Dazzi F. The immunosuppressive effects of human bone marrow-derived mesenchymal stem cells target T cell proliferation but not its effector function. Cellular Immunology 2008; 251: 131-136.
42. Le Blanc K. Immunomodulatory effects of fetal and adult mesenchymal stem cells. Cytotherapy 2003; 5: 485-489.
43. Yoshikawa T, Ohgushi H, Nakajima H, Yamada E, Ichijima K, Tamai S, Ohta T. In vivo osteogenic durability of cultured bone in porous ceramics: a novel method for autogenous bone graft substitution. Transplantation 2000; 69: 128-134.
44. Both SK, van der Muijsenberg AJ, van Blitterswijk CA, de Boer J, de Bruijn JD. A rapid and efficient method for expansion of human mesenchymal stem cells. Tissue Engineering 2007; 13: 3-9.
45. Mendes SC, Van Den Brink I, De Bruijn JD, Van Blitterswijk CA. In vivo bone formation by human bone marrow cells: effect of osteogenic culture supplements and cell densities. Journal of Materials Science: Materials in Medicine 1998; 9: 855-858.
46. Scotti C, Tonnarelli B, Papadimitropoulos A, Scherberich A, Schaeren S, Schauerte A, Lopez-Rios J, Zeller R, Barbero A, Martin I. Recapitulation of endochondral bone formation using human adult mesenchymal stem cells as a paradigm for developmental engineering. Proceedings of the National Academy of Sciences of the United States 2010; 107: 7251-7256.
47. Blum JS, Barry MA, Mikos AG, Jansen JA. In vivo evaluation of gene therapy vectors in ex vivoderived marrow stromal cells for bone regeneration in a rat critical-size calvarial defect model. Human Gene Therapy 2003; 14: 1689-1701.
48. Nather A, David V, Teng JW, Lee CW, Pereira BP. Effect of autologous mesenchymal stem cells on biological healing of allografts in critical-sized tibial defects simulated in adult rabbits. ANNALS Academy of Medicine Singapore 2010; 39: 599-606.
49. Bruder SP, Kraus KH, Goldberg VM, Kadiyala S. The Effect of Implants Loaded with Autologous Mesenchymal Stem Cells on the Healing of Canine Segmental Bone Defects. The Journal of Bone & Joint Surgery 1998; 80: 985-996.
50. van Gaalen SM, Dhert WJ, van den Muysenberg A, Oner FC, van Blitterswijk C, verbout AJ, de Bruijn JD. Bone tissue engineering for spine fusion: an experimental study on ectopic and orthotopic implants in rats. Tissue Engineering 2004; 10: 231-239.
51. Oliveira SM, Mijares DQ, Turner G, Amaral IF, Barbosa MA, Teixeira CC. Engineering endochondral bone: in vivo studies. Tissue Engineering Part A 2009; 15: 635-643.
52. Zuk PA, Zhu M, Mizuno H, Huang J, Futrell JW, Katz AJ, Benhaim P, Lorenz HP, Hedrick MH. Multilineage cells from human adipose tissue: implications for cell-based therapies. Tissue Engineering 2001; 7: 211-228.
53. Gimble JM, Katz AJ, Bunnell BA. Adipose-Derived Stem Cells for Regenerative Medicine. Circulation Research 2007; 100: 1249-1260.
54. Jurgens WJ, Oedayrajsingh-Varma MJ, Helder MN, Zandiehdoulabi B, Schouten TE, Kuik DJ, Ritt MJ, van Milligen FJ. Effect of tissueharvesting site on yield of stem cells derived from adipose tissue: implications for cell-based therapies. Cell and Tissue Research 2008; 332: 415-426.
55. Nishida S, Endo N, Yamagiwa H, Tanizawa T, Takahashi HE. Number of osteoprogenitor cells in human bone marrow markedly decreases after skeletal maturation. Journal of Bone Mineral Metabolism 1999; 17: 171-177.
56. Stenderup K, Justesen J, Clausen C, Kassem M. Aging is associated with decreased maximal life span and accelerated senescence of bone marrow stromal cells. Bone 2003; 33: 919-926.
57. Mueller SM, Glowacki J. Age-related decline in the osteogenic potential of human bone marrow cells cultured in three-dimensional collagen sponges. Journal of Cell Biochemistry 2001; 82: 583-590.
58. Bianco P, Riminucci M, Gronthos S, Robey PG. Bone marrow stromal stem cells: nature, biology, and potential applications. Stem Cells 2001; 19: 180-192.
59. Simonsen JL, Rosada C, Serakinci N, Justesen J, Stenderup K, Rattan SI, Jensen TG, Kassem M. Telomerase expression extends the proliferative life-span and maintains the osteogenic potential of human bone marrow stromal cells. Nature Biotechnology 2002; 20: 592-596.
60. Shi S, Gronthos S, Chen S, Reddi A, Counter CM, Robey PG, Wang CY. Bone formation by human postnatal bone marrow stromal stem cells is enhanced by telomerase expression. Nature Biotechnology 2002; 20: 587-591.
61. Kim D, Kim C, Moon JI, Chung YG, Chang MY, Han BS, Ko S, Yang E, Cha KY, Lanza R, Kim KS. Generation of human induced pluripotent stem cells by direct delivery of reprogramming proteins. Cell Stem Cell 2009; 4: 472-476.
62. Warren L, Manos PD, Ahfeldt T, Loh YH, Li H, Lau F, Ebina W, Mandal PK, Smith ZD, Meissner A, Daley GQ, Brack AS, Collins JJ, Cowan C, Schlaeger TM, Rossi DJ. Highly Efficient Reprogramming to Pluripotency and Directed Differentiation of Human Cells with Synthetic Modified mRNA. Cell Stem Cell 2010; 7: 618-630.