The derivation of mesenchymal stem cells from human embryonic stem cells

Cells Tissues Organs

Volumn 189, Issue 1-4, 2008, Pages 256-260

  Brown, Shelley E ^a   Tong, Wilbur ^a   Krebsbach, Paul H ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

Author keywords

Human embryonic stem cells; Mesenchymal stem cells; Osteoblasts; Osteoprogenitor cells

Indexed keywords

GREEN FLUORESCENT PROTEIN;

ADIPOCYTE; CELL DIFFERENTIATION; CONFERENCE PAPER; CONTROLLED STUDY; EMBRYONIC STEM CELL; HUMAN; HUMAN CELL; IMMUNOPHENOTYPING; LENTIVIRINAE; MESENCHYMAL STEM CELL; OSTEOBLAST; PRIORITY JOURNAL; PROTEIN EXPRESSION;

BIOLOGICAL MARKERS; CELL DIFFERENTIATION; CELL LINEAGE; CELLS, CULTURED; EMBRYONIC STEM CELLS; GREEN FLUORESCENT PROTEINS; HUMANS; LENTIVIRUS; MESENCHYMAL STEM CELLS; TRANSDUCTION, GENETIC;

LENTIVIRUS;

EID: 57449120498     PISSN: 14226405     EISSN: None     Source Type: Journal    
DOI: 10.1159/000151746     Document Type: Conference Paper

References (19)

1. Ahn, S., S. Kim, K. Park, S. Moon, H. Lee, G. Kim, Y. Lee, K. Park, K. Cha, H. Chung (2006) Primary bone-derived cells induce osteogenic differentiation without exogenous factors in human embryonic stem cells. Biochem Biophys Res Commun 340: 403-408.
2. Barberi, T., L.M. Willis, N.D. Socci, L. Studer (2005) Derivation of multipotent mesenchymal precursors from human embryonic stem cells. PLoS Med 2: e161.
3. Bianco, P., M. Riminucci, S. Gronthos, P. Robey (2003) Bone marrow stromal stem cells: nature, biology, and potential applications. Stem Cells 19: 180-192.
4. Cao, T., B. Heng, C. Ye, H. Liu, W. Toh, P. Robson, P. Li, Y. Hong, L. Stanton (2005) Osteogenic differentiation within intact human embryoid bodies result in a marked increase in osteocalcin secretion after 12 days of in vitro culture, and formation of morphologically distinct nodule-like structures. Tissue Cell 37: 325-334.
5. Duplomb, L., M. Dagouassat, P. Jourdon, D. Heymann (2007) Concise review: embryonic stem cells: a new tool to study osteoblast and osteoclast differentiation. Stem Cells 25: 544-552.
6. Gronthos, S., S.E. Graves, S. Ohta, P.J. Simmons (1994) The STRO-1+ fraction of adult human bone marrow contains the osteogenic precursors. Blood 84: 4164-4173.
7. Gronthos, S., A.C.W. Zannettino, S.E. Graves, S. Ohta, S.J. Hay, P.J. Simmons (1999) Differential cell surface expression of the STRO-1 and alkaline phosphatase antigens on discrete developmental stages in primary cultures of human bone cells. J Bone Miner Res 14: 47-56.
8. Kalajzic, I., Z. Kalajzic, S. Clark, A. Lichtler, D. Rowe (2002) Use of Col1a1GFP transgenes to identify subpopulations of cells at different stages of the osteoblast lineage. J Bone Miner Res 17: 15-25.
9. Kalajzic, I., A. Staal, W. Yang, Y. Wu, S. Johnson, J. Feyen, W. Krueger, P. Maye, F. Yu, Y. Zhao, L. Kuo, R. Gupta, L. Achenie, H. Wang, D. Shin, D. Rowe (2005) Expression profile of osteoblastic lineage at defined stages of differentiation. J Biol Chem 280: 24618-24626.
10. Karp, J., L. Ferreira, A. Khademhosseini, A. Kwon, J. Yeh, R. Langer (2006) Cultivation of human embryonic stem cells without the embryoid body step enhances osteogenesis in vitro. Stem Cells 24: 835-843.
11. Krebsbach, P.H., J.R. Harrison, A.C. Lichtler, C. O. Woody, D.W. Rowe, B.E. Kream (1993) Transgenic expression of COL1A1-chloramphenicol acetyltransferase fusion genes in bone: differential utilization of promoter elements in vivo and in cultured cells. Mol Cell Biol 13: 5168-5174.
12. Lian, Q., E. Lye, K.S. Yeo, E.K.W. Tan, M. Salto-Tellez, T.M. Liu, N. Palanisamy, R.M. El Oakley, E.H. Lee, B. Lim, S. Lim (2007) Derivation of clinically compliant MSCs from CD105+, CD24-differentiated human ESCs. Stem Cells 25: 425-436.
13. Olivier, E., A.C. Rybicki, E.E. Bouhassira (2006) Differentiation of human embryonic stem cells into bipotent mesenchymal stem cells. Stem Cells 24: 1914-1922.
14. Pittenger, M., A. Mackay, S. Beck (1996) Human mesenchymal stem cells can be directed into chondrocytes, adipocytes or osteocytes. Mol Biol Cell 7: 305a.
15. Sotille, V., A. Thomson, J. McWhir (2003) In vitro osteogenic differentiation of human ES cells. Cloning Stem Cells 5: 149-155.
16. Stewart, K., S. Walsh, J. Screen, C.M. Jefferiss, J. Chainey, G. Jordan, J.N. Beresford (1999) Further characterization of cells expressing STRO-1 in cultures of adult human bone marrow stromal cells. Jf Bone Miner Res 14: 1345-1356.
17. Thomson, J., J. Itskovitz-Eldor, S. Shapiro, M. Waknitz, J. Swiergiel, V. Marshall, J. Jones (1998) Embryonic stem cell lines derived from human blastocysts. Science 282: 1145-1147.
18. Tong, W., S.E. Brown, P.H. Krebsbach (2007) Human embryonic stem cells undergo osteogenic differentiation in human bone marrow stromal cell microenvironments. J Stem Cells 2: 139-147.
19. Wagers, A., I. Weissman (2004) Plasticity of adult stem cells. Cells 116: 639-648.