-
1
-
-
0033971515
-
The utilization of recombinant prostanoid receptors to determine the affinities and selectivities of prostaglandins and related analogs
-
Abramovitz M, Adam M, Boie Y, Carriere M, Denis D, Godbout C, Lamontagne S, Rochette C, Sawyer N, Tremblay NM, Belley M, Gallant M, Dufresne C, Gareau Y, Ruel R, Juteau H, Labelle M, Ouimet N, Metters KM (2000) The utilization of recombinant prostanoid receptors to determine the affinities and selectivities of prostaglandins and related analogs. Biochim Biophys Acta 1483:285-293
-
(2000)
Biochim Biophys Acta
, vol.1483
, pp. 285-293
-
-
Abramovitz, M.1
Adam, M.2
Boie, Y.3
Carriere, M.4
Denis, D.5
Godbout, C.6
Lamontagne, S.7
Rochette, C.8
Sawyer, N.9
Tremblay, N.M.10
Belley, M.11
Gallant, M.12
Dufresne, C.13
Gareau, Y.14
Ruel, R.15
Juteau, H.16
Labelle, M.17
Ouimet, N.18
Metters, K.M.19
-
2
-
-
0033679134
-
Epoprostenol (prostacyclin) therapy in HIV-associated pulmonary hypertension
-
Aguilar RV, Farber HW (2000) Epoprostenol (prostacyclin) therapy in HIV-associated pulmonary hypertension. Am J Respir Crit Care Med 162:1846-1850
-
(2000)
Am J Respir Crit Care Med
, vol.162
, pp. 1846-1850
-
-
Aguilar, R.V.1
Farber, H.W.2
-
3
-
-
17144452827
-
Continuous intravenous epoprostenol for pulmonary hypertension due to the scleroderma spectrum of disease. A randomized, controlled trial
-
Badesch DB, Tapson VF, McGoon MD, Brundage BH, Rubin LJ, Wigley FM, Rich S, Barst RJ, Barrett PS, Kral KM, Jobsis MM, Loyd JE, Murali S, Frost A, Girgis R, Bourge RC, Ralph DD, Elliott CG, Hill NS, Langleben D, Schilz RJ, McLaughlin VV, Robbins IM, Groves BM, Shapiro S, Medsger TA Jr (2000) Continuous intravenous epoprostenol for pulmonary hypertension due to the scleroderma spectrum of disease. A randomized, controlled trial. Ann Intern Med 132:425-434
-
(2000)
Ann Intern Med
, vol.132
, pp. 425-434
-
-
Badesch, D.B.1
Tapson, V.F.2
McGoon, M.D.3
Brundage, B.H.4
Rubin, L.J.5
Wigley, F.M.6
Rich, S.7
Barst, R.J.8
Barrett, P.S.9
Kral, K.M.10
Jobsis, M.M.11
Loyd, J.E.12
Murali, S.13
Frost, A.14
Girgis, R.15
Bourge, R.C.16
Ralph, D.D.17
Elliott, C.G.18
Hill, N.S.19
Langleben, D.20
Schilz, R.J.21
McLaughlin, V.V.22
Robbins, I.M.23
Groves, B.M.24
Shapiro, S.25
Medsger Jr., T.A.26
more..
-
4
-
-
34250870730
-
Medical therapy for pulmonary arterial hypertension: Updated ACCP evidence-based clinical practice guidelines
-
Badesch DB, Abman SH, Simonneau G, Rubin LJ, McLaughlin VV (2007) Medical therapy for pulmonary arterial hypertension: Updated ACCP evidence-based clinical practice guidelines. Chest 131:1917-1928
-
(2007)
Chest
, vol.131
, pp. 1917-1928
-
-
Badesch, D.B.1
Abman, S.H.2
Simonneau, G.3
Rubin, L.J.4
McLaughlin, V.V.5
-
5
-
-
0036660618
-
Has angiogenesis been invited to the PPARty
-
Barger PM (2002) Has angiogenesis been invited to the PPARty J Mol Cell Cardiol 34:713-716
-
(2002)
J Mol Cell Cardiol
, vol.34
, pp. 713-716
-
-
Barger, P.M.1
-
6
-
-
0030031888
-
A comparison of continuous intravenous epoprostenol (prostacyclin) with conventional therapy for primary pulmonary hypertension
-
The Primary Pulmonary Hypertension Study Group
-
Barst RJ, Rubin LJ, Long WA, McGoon MD, Rich S, Badesch DB, Groves BM, Tapson VF, Bourge RC, Brundage BH (1996) A comparison of continuous intravenous epoprostenol (prostacyclin) with conventional therapy for primary pulmonary hypertension. The Primary Pulmonary Hypertension Study Group. N Engl J Med 334:296-302
-
(1996)
N Engl J Med
, vol.334
, pp. 296-302
-
-
Barst, R.J.1
Rubin, L.J.2
Long, W.A.3
McGoon, M.D.4
Rich, S.5
Badesch, D.B.6
Groves, B.M.7
Tapson, V.F.8
Bourge, R.C.9
Brundage, B.H.10
-
7
-
-
0038037766
-
Beraprost therapy for pulmonary arterial hypertension
-
Barst RJ, McGoon M, McLaughlin V, Tapson V, Rich S, Rubin L, Wasserman K, Oudiz R, Shapiro S, Robbins IM, Channick R, Badesch D, Rayburn BK, Flinchbaugh R, Sigman J, Arneson C, Jeffs R (2003) Beraprost therapy for pulmonary arterial hypertension. J Am Coll Cardiol 41:2119-2125
-
(2003)
J Am Coll Cardiol
, vol.41
, pp. 2119-2125
-
-
Barst, R.J.1
McGoon, M.2
McLaughlin, V.3
Tapson, V.4
Rich, S.5
Rubin, L.6
Wasserman, K.7
Oudiz, R.8
Shapiro, S.9
Robbins, I.M.10
Channick, R.11
Badesch, D.12
Rayburn, B.K.13
Flinchbaugh, R.14
Sigman, J.15
Arneson, C.16
Jeffs, R.17
-
8
-
-
33845360014
-
Long-term outcome in pulmonary arterial hypertension patients treated with subcutaneous treprostinil
-
Barst RJ, Galie N, Naeije R, Simonneau G, Jeffs R, Arneson C, Rubin LJ (2006) Long-term outcome in pulmonary arterial hypertension patients treated with subcutaneous treprostinil. Eur Respir J 28:1195-1203
-
(2006)
Eur Respir J
, vol.28
, pp. 1195-1203
-
-
Barst, R.J.1
Galie, N.2
Naeije, R.3
Simonneau, G.4
Jeffs, R.5
Arneson, C.6
Rubin, L.J.7
-
9
-
-
13044263122
-
Nuclear localization of prostaglandin E2 receptors
-
Bhattacharya M, Peri KG, Almazan G, Ribeiro-da-Silva A, Shichi H, Durocher Y, Abramovitz M, Hou X, Varma DR, Chemtob S (1998) Nuclear localization of prostaglandin E2 receptors. Proc Natl Acad Sci USA 95:15792-15797
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 15792-15797
-
-
Bhattacharya, M.1
Peri, K.G.2
Almazan, G.3
Ribeiro-Da-Silva, A.4
Shichi, H.5
Durocher, Y.6
Abramovitz, M.7
Hou, X.8
Varma, D.R.9
Chemtob, S.10
-
10
-
-
0033024889
-
Localization of functional prostaglandin E2 receptors EP3 and EP4 in the nuclear envelope
-
Bhattacharya M, Peri K, Ribeiro-da-Silva A, Almazan G, Shichi H, Hou X, Varma DR, Chemtob S (1999) Localization of functional prostaglandin E2 receptors EP3 and EP4 in the nuclear envelope. J Biol Chem 274:15719-15724
-
(1999)
J Biol Chem
, vol.274
, pp. 15719-15724
-
-
Bhattacharya, M.1
Peri, K.2
Ribeiro-Da-Silva, A.3
Almazan, G.4
Shichi, H.5
Hou, X.6
Varma, D.R.7
Chemtob, S.8
-
11
-
-
0030853952
-
A randomized controlled trial of epoprostenol therapy for severe congestive heart failure: The flolan international randomized survival trial (FIRST)
-
Califf RM, Adams KF, McKenna WJ, Gheorghiade M, Uretsky BF, McNulty SE, Darius H, Schulman K, Zannad F, Handberg-Thurmond E, Harrell FE Jr, Wheeler W, Soler-Soler J, Swedberg K (1997) A randomized controlled trial of epoprostenol therapy for severe congestive heart failure: The Flolan International Randomized Survival Trial (FIRST). Am Heart J 134:44-54
-
(1997)
Am Heart J
, vol.134
, pp. 44-54
-
-
Califf, R.M.1
Adams, K.F.2
McKenna, W.J.3
Gheorghiade, M.4
Uretsky, B.F.5
McNulty, S.E.6
Darius, H.7
Schulman, K.8
Zannad, F.9
Handberg-Thurmond, E.10
Harrell Jr., F.E.11
Wheeler, W.12
Soler-Soler, J.13
Swedberg, K.14
-
12
-
-
33748931278
-
Safety and efficacy of inhaled treprostinil as add-on therapy to bosentan in pulmonary arterial hypertension
-
Channick RN, Olschewski H, Seeger W, Staub T, Voswinckel R, Rubin LJ (2006) Safety and efficacy of inhaled treprostinil as add-on therapy to bosentan in pulmonary arterial hypertension. J Am Coll Cardiol 48:1433-1437
-
(2006)
J Am Coll Cardiol
, vol.48
, pp. 1433-1437
-
-
Channick, R.N.1
Olschewski, H.2
Seeger, W.3
Staub, T.4
Voswinckel, R.5
Rubin, L.J.6
-
13
-
-
0142043475
-
Protein kinase A-dependent coupling of mouse prostacyclin receptors to Gi is cell-type dependent
-
Chow KB, Jones RL, Wise H (2003) Protein kinase A-dependent coupling of mouse prostacyclin receptors to Gi is cell-type dependent. Eur J Pharmacol 474:7-13
-
(2003)
Eur J Pharmacol
, vol.474
, pp. 7-13
-
-
Chow, K.B.1
Jones, R.L.2
Wise, H.3
-
14
-
-
0036007307
-
Differential effects of stable prostacyclin analogs on smooth muscle proliferation and cyclic AMP generation in human pulmonary artery
-
Clapp LH, Finney P, Turcato S, Tran S, Rubin LJ, Tinker A (2002) Differential effects of stable prostacyclin analogs on smooth muscle proliferation and cyclic AMP generation in human pulmonary artery. Am J Respir Cell Mol Biol 26:194-201
-
(2002)
Am J Respir Cell Mol Biol
, vol.26
, pp. 194-201
-
-
Clapp, L.H.1
Finney, P.2
Turcato, S.3
Tran, S.4
Rubin, L.J.5
Tinker, A.6
-
15
-
-
80052687748
-
Does the outcome justify an oral-first treatment strategy for management of pulmonary arterial hypertension
-
Cornwell WK, McLaughlin VV, Krishnan SM, Rubenfire M (2011) Does the outcome justify an oral-first treatment strategy for management of pulmonary arterial hypertension Chest 140:697-705
-
(2011)
Chest
, vol.140
, pp. 697-705
-
-
Cornwell, W.K.1
McLaughlin, V.V.2
Krishnan, S.M.3
Rubenfire, M.4
-
16
-
-
33947574300
-
Continuous intravenous iloprost to revert treatment failure of first-line inhaled iloprost therapy in patients with idiopathic pulmonary arterial hypertension
-
Ewert R, Opitz CF, Wensel R, Winkler J, Halank M, Felix SB (2007) Continuous intravenous iloprost to revert treatment failure of first-line inhaled iloprost therapy in patients with idiopathic pulmonary arterial hypertension. Clin Res Cardiol 96:211-217
-
(2007)
Clin Res Cardiol
, vol.96
, pp. 211-217
-
-
Ewert, R.1
Opitz, C.F.2
Wensel, R.3
Winkler, J.4
Halank, M.5
Felix, S.B.6
-
17
-
-
34447563745
-
Treprostinil potentiates the positive inotropic effect of catecholamines in adult rat ventricular cardiomyocytes
-
Fontana M, Olschewski H, Olschewski A, Schluter KD (2007) Treprostinil potentiates the positive inotropic effect of catecholamines in adult rat ventricular cardiomyocytes. Br J Pharmacol 151:779-786
-
(2007)
Br J Pharmacol
, vol.151
, pp. 779-786
-
-
Fontana, M.1
Olschewski, H.2
Olschewski, A.3
Schluter, K.D.4
-
18
-
-
0029002298
-
Unique response pathways are established by allosteric interactions among nuclear hormone receptors
-
Forman BM, Umesono K, Chen J, Evans RM (1995) Unique response pathways are established by allosteric interactions among nuclear hormone receptors. Cell 81:541-550
-
(1995)
Cell
, vol.81
, pp. 541-550
-
-
Forman, B.M.1
Umesono, K.2
Chen, J.3
Evans, R.M.4
-
19
-
-
0036569119
-
Effects of beraprost sodium, an oral prostacyclin analogue, in patients with pulmonary arterial hypertension: A randomized, double-blind, placebo-controlled trial
-
Galie N, Humbert M, Vachiery JL, Vizza CD, Kneussl M, Manes A, Sitbon O, Torbicki A, Delcroix M, Naeije R, Hoeper M, Chaouat A, Morand S, Besse B, Simonneau G (2002) Effects of beraprost sodium, an oral prostacyclin analogue, in patients with pulmonary arterial hypertension: A randomized, double-blind, placebo-controlled trial. J Am Coll Cardiol 39:1496-1502
-
(2002)
J Am Coll Cardiol
, vol.39
, pp. 1496-1502
-
-
Galie, N.1
Humbert, M.2
Vachiery, J.L.3
Vizza, C.D.4
Kneussl, M.5
Manes, A.6
Sitbon, O.7
Torbicki, A.8
Delcroix, M.9
Naeije, R.10
Hoeper, M.11
Chaouat, A.12
Morand, S.13
Besse, B.14
Simonneau, G.15
-
20
-
-
70049112901
-
Guidelines for the diagnosis and treatment of pulmonary hypertension: The task force for the diagnosis and treatment of pulmonary hypertension of the european society of cardiology (esc) and the european respiratory society (ers), endorsed by the international society of heart and lung transplantation (ishlt)
-
Galie N, Hoeper MM, Humbert M, Torbicki A, Vachiery JL, Barbera JA, Beghetti M, Corris P, Gaine S, Gibbs JS, Gomez-Sanchez MA, Jondeau G, Klepetko W, Opitz C, Peacock A, Rubin L, Zellweger M, Simonneau G, Vahanian A, Auricchio A, Bax J, Ceconi C, Dean V, Filippatos G, Funck-Brentano C, Hobbs R, Kearney P, McDonagh T, McGregor K, Popescu BA, Reiner Z, Sechtem U, Sirnes PA, Tendera M, Vardas P, Widimsky P, Sechtem U, Al AN, Andreotti F, Aschermann M, Asteggiano R, Benza R, Berger R, Bonnet D, Delcroix M, Howard L, Kitsiou AN, Lang I, Maggioni A, Nielsen-Kudsk JE, Park M, Perrone-Filardi P, Price S, Domenech MT, Vonk-Noordegraaf A, Zamorano JL (2009) Guidelines for the diagnosis and treatment of pulmonary hypertension: The Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS), endorsed by the International Society of Heart and Lung Transplantation (ISHLT). Eur Heart J 30:2493-2537
-
(2009)
Eur Heart J
, vol.30
, pp. 2493-2537
-
-
Galie, N.1
Hoeper, M.M.2
Humbert, M.3
Torbicki, A.4
Vachiery, J.L.5
Barbera, J.A.6
Beghetti, M.7
Corris, P.8
Gaine, S.9
Gibbs, J.S.10
Gomez-Sanchez, M.A.11
Jondeau, G.12
Klepetko, W.13
Opitz, C.14
Peacock, A.15
Rubin, L.16
Zellweger, M.17
Simonneau, G.18
Vahanian, A.19
Auricchio, A.20
Bax, J.21
Ceconi, C.22
Dean, V.23
Filippatos, G.24
Funck-Brentano, C.25
Hobbs, R.26
Kearney, P.27
McDonagh, T.28
McGregor, K.29
Popescu, B.A.30
Reiner, Z.31
Sechtem, U.32
Sirnes, P.A.33
Tendera, M.34
Vardas, P.35
Widimsky, P.36
Sechtem, U.37
Al, A.N.38
Andreotti, F.39
Aschermann, M.40
Asteggiano, R.41
Benza, R.42
Berger, R.43
Bonnet, D.44
Delcroix, M.45
Howard, L.46
Kitsiou, A.N.47
Lang, I.48
Maggioni, A.49
Nielsen-Kudsk, J.E.50
Park, M.51
Perrone-Filardi, P.52
Price, S.53
Domenech, M.T.54
Vonk-Noordegraaf, A.55
Zamorano, J.L.56
more..
-
21
-
-
0037006966
-
Combination therapy with oral sildenafil and inhaled iloprost for severe pulmonary hypertension
-
Ghofrani HA, Wiedemann R, Rose F, Olschewski H, Schermuly RT, Weissmann N, Seeger W, Grimminger F (2002) Combination therapy with oral sildenafil and inhaled iloprost for severe pulmonary hypertension. Ann Intern Med 136:515-522
-
(2002)
Ann Intern Med
, vol.136
, pp. 515-522
-
-
Ghofrani, H.A.1
Wiedemann, R.2
Rose, F.3
Olschewski, H.4
Schermuly, R.T.5
Weissmann, N.6
Seeger, W.7
Grimminger, F.8
-
22
-
-
0037868048
-
Oral sildenafil as long-term adjunct therapy to inhaled iloprost in severe pulmonary arterial hypertension
-
Ghofrani HA, Rose F, Schermuly RT, Olschewski H, Wiedemann R, Kreckel A, Weissmann N, Ghofrani S, Enke B, Seeger W, Grimminger F (2003) Oral sildenafil as long-term adjunct therapy to inhaled iloprost in severe pulmonary arterial hypertension. J Am Coll Cardiol 42:158-164
-
(2003)
J Am Coll Cardiol
, vol.42
, pp. 158-164
-
-
Ghofrani, H.A.1
Rose, F.2
Schermuly, R.T.3
Olschewski, H.4
Wiedemann, R.5
Kreckel, A.6
Weissmann, N.7
Ghofrani, S.8
Enke, B.9
Seeger, W.10
Grimminger, F.11
-
23
-
-
1042263812
-
Inhaled iloprost is a potent acute pulmonary vasodilator in HIV-related severe pulmonary hypertension
-
Ghofrani HA, Friese G, Discher T, Olschewski H, Schermuly RT, Weissmann N, Seeger W, Grimminger F, Lohmeyer J (2004) Inhaled iloprost is a potent acute pulmonary vasodilator in HIV-related severe pulmonary hypertension. Eur Respir J 23:321-326
-
(2004)
Eur Respir J
, vol.23
, pp. 321-326
-
-
Ghofrani, H.A.1
Friese, G.2
Discher, T.3
Olschewski, H.4
Schermuly, R.T.5
Weissmann, N.6
Seeger, W.7
Grimminger, F.8
Lohmeyer, J.9
-
24
-
-
42949166212
-
Prostacyclin therapies for the treatment of pulmonary arterial hypertension
-
Gomberg-Maitland M, Olschewski H (2008) Prostacyclin therapies for the treatment of pulmonary arterial hypertension. Eur Respir J 31:891-901
-
(2008)
Eur Respir J
, vol.31
, pp. 891-901
-
-
Gomberg-Maitland, M.1
Olschewski, H.2
-
25
-
-
30444458863
-
Transition from intravenous epoprostenol to intravenous treprostinil in pulmonary hypertension
-
Gomberg-Maitland M, Tapson VF, Benza RL, McLaughlin VV, Krichman A, Widlitz AC, Barst RJ (2005a) Transition from intravenous epoprostenol to intravenous treprostinil in pulmonary hypertension. Am J Respir Crit Care Med 172:1586-1589
-
(2005)
Am J Respir Crit Care Med
, vol.172
, pp. 1586-1589
-
-
Gomberg-Maitland, M.1
Tapson, V.F.2
Benza, R.L.3
McLaughlin, V.V.4
Krichman, A.5
Widlitz, A.C.6
Barst, R.J.7
-
26
-
-
27144440344
-
Efficacy and safety of sildenafil added to treprostinil in pulmonary hypertension
-
Gomberg-Maitland M, McLaughlin V, Gulati M, Rich S (2005b) Efficacy and safety of sildenafil added to treprostinil in pulmonary hypertension. Am J Cardiol 96:1334-1336
-
(2005)
Am J Cardiol
, vol.96
, pp. 1334-1336
-
-
Gomberg-Maitland, M.1
McLaughlin, V.2
Gulati, M.3
Rich, S.4
-
27
-
-
84907036107
-
Prostaglandins, platelets, and atherosclerosis
-
Gryglewski RJ (1980) Prostaglandins, platelets, and atherosclerosis. CRC Crit Rev Biochem 7:291-338
-
(1980)
CRC Crit Rev Biochem
, vol.7
, pp. 291-338
-
-
Gryglewski, R.J.1
-
28
-
-
84865648810
-
Computed tomography findings of pulmonary venoocclusive disease in scleroderma patients presenting with precapillary pulmonary hypertension
-
Gunther S, Jais X, Maitre S, Berezne A, Dorfmuller P, Seferian A, Savale L, Mercier O, Fadel E, Sitbon O, Mouthon L, Simonneau G, Humbert M, Montani D (2012) Computed tomography findings of pulmonary venoocclusive disease in scleroderma patients presenting with precapillary pulmonary hypertension. Arthritis Rheum 64:2995-3005
-
(2012)
Arthritis Rheum
, vol.64
, pp. 2995-3005
-
-
Gunther, S.1
Jais, X.2
Maitre, S.3
Berezne, A.4
Dorfmuller, P.5
Seferian, A.6
Savale, L.7
Mercier, O.8
Fadel, E.9
Sitbon, O.10
Mouthon, L.11
Simonneau, G.12
Humbert, M.13
Montani, D.14
-
29
-
-
0034700110
-
Prostacyclinmediated activation of peroxisome proliferator-activated receptor delta in colorectal cancer
-
Gupta RA, Tan J, Krause WF, Geraci MW, Willson TM, Dey SK, DuBois RN (2000) Prostacyclinmediated activation of peroxisome proliferator-activated receptor delta in colorectal cancer. Proc Natl Acad Sci USA 97:13275-13280
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 13275-13280
-
-
Gupta, R.A.1
Tan, J.2
Krause, W.F.3
Geraci, M.W.4
Willson, T.M.5
Dey, S.K.6
Dubois, R.N.7
-
30
-
-
84455189008
-
The experiences of patients with pulmonary arterial hypertension receiving continuous intravenous infusion of epoprostenol (Flolan) and their support persons
-
Hall H, Cote J, McBean A, Purden M (2012) The experiences of patients with pulmonary arterial hypertension receiving continuous intravenous infusion of epoprostenol (Flolan) and their support persons. Heart Lung 41:35-43
-
(2012)
Heart Lung
, vol.41
, pp. 35-43
-
-
Hall, H.1
Cote, J.2
McBean, A.3
Purden, M.4
-
31
-
-
0035824652
-
Prostacyclin-dependent apoptosis mediated by PPAR delta
-
Hatae T, Wada M, Yokoyama C, Shimonishi M, Tanabe T (2001) Prostacyclin-dependent apoptosis mediated by PPAR delta. J Biol Chem 276:46260-46267
-
(2001)
J Biol Chem
, vol.276
, pp. 46260-46267
-
-
Hatae, T.1
Wada, M.2
Yokoyama, C.3
Shimonishi, M.4
Tanabe, T.5
-
32
-
-
0021367046
-
Long-term treatment of primary pulmonary hypertension with continuous intravenous epoprostenol (prostacyclin)
-
Higenbottam T, Wheeldon D, Wells F, Wallwork J (1984) Long-term treatment of primary pulmonary hypertension with continuous intravenous epoprostenol (prostacyclin). Lancet 1:1046-1047
-
(1984)
Lancet
, vol.1
, pp. 1046-1047
-
-
Higenbottam, T.1
Wheeldon, D.2
Wells, F.3
Wallwork, J.4
-
33
-
-
0031920988
-
Treatment of pulmonary hypertension with the continuous infusion of a prostacyclin analogue, iloprost
-
Higenbottam TW, Butt AY, Dinh-Xuan AT, Takao M, Cremona G, Akamine S (1998) Treatment of pulmonary hypertension with the continuous infusion of a prostacyclin analogue, iloprost. Heart 79:175-179
-
(1998)
Heart
, vol.79
, pp. 175-179
-
-
Higenbottam, T.W.1
Butt, A.Y.2
Dinh-Xuan, A.T.3
Takao, M.4
Cremona, G.5
Akamine, S.6
-
34
-
-
0041742185
-
Bosentan treatment in patients with primary pulmonary hypertension receiving nonparenteral prostanoids
-
Hoeper MM, Taha N, Bekjarova A, Gatzke R, Spiekerkoetter E (2003) Bosentan treatment in patients with primary pulmonary hypertension receiving nonparenteral prostanoids. Eur Respir J 22:330-334
-
(2003)
Eur Respir J
, vol.22
, pp. 330-334
-
-
Hoeper, M.M.1
Taha, N.2
Bekjarova, A.3
Gatzke, R.4
Spiekerkoetter, E.5
-
35
-
-
33847368988
-
Combining inhaled iloprost with bosentan in patients with idiopathic pulmonary arterial hypertension
-
Hoeper MM, Leuchte H, Halank M, Wilkens H, Meyer FJ, Seyfarth HJ, Wensel R, Ripken F, Bremer H, Kluge S, Hoeffken G, Behr J (2006) Combining inhaled iloprost with bosentan in patients with idiopathic pulmonary arterial hypertension. Eur Respir J 28:691-694
-
(2006)
Eur Respir J
, vol.28
, pp. 691-694
-
-
Hoeper, M.M.1
Leuchte, H.2
Halank, M.3
Wilkens, H.4
Meyer, F.J.5
Seyfarth, H.J.6
Wensel, R.7
Ripken, F.8
Bremer, H.9
Kluge, S.10
Hoeffken, G.11
Behr, J.12
-
36
-
-
0032790301
-
Short-term and long-term epoprostenol (prostacyclin) therapy in pulmonary hypertension secondary to connective tissue diseases: Results of a pilot study
-
Humbert M, Sanchez O, Fartoukh M, Jagot JL, Le Gall C, Sitbon O, Parent F, Simonneau G (1999) Short-term and long-term epoprostenol (prostacyclin) therapy in pulmonary hypertension secondary to connective tissue diseases: Results of a pilot study. Eur Respir J 13:1351-1356
-
(1999)
Eur Respir J
, vol.13
, pp. 1351-1356
-
-
Humbert, M.1
Sanchez, O.2
Fartoukh, M.3
Jagot, J.L.4
Le Gall, C.5
Sitbon, O.6
Parent, F.7
Simonneau, G.8
-
37
-
-
4544383466
-
Combination of bosentan with epoprostenol in pulmonary arterial hypertension: BREATHE-2
-
Humbert M, Barst RJ, Robbins IM, Channick RN, Galie N, Boonstra A, Rubin LJ, Horn EM, Manes A, Simonneau G (2004) Combination of bosentan with epoprostenol in pulmonary arterial hypertension: BREATHE-2. Eur Respir J 24:353-359
-
(2004)
Eur Respir J
, vol.24
, pp. 353-359
-
-
Humbert, M.1
Barst, R.J.2
Robbins, I.M.3
Channick, R.N.4
Galie, N.5
Boonstra, A.6
Rubin, L.J.7
Horn, E.M.8
Manes, A.9
Simonneau, G.10
-
38
-
-
38048999613
-
Short-and long-term effects of inhaled iloprost therapy in children with pulmonary arterial hypertension
-
Ivy DD, Doran AK, Smith KJ, Mallory GB Jr, Beghetti M, Barst RJ, Brady D, Law Y, Parker D, Claussen L, Abman SH (2008) Short-and long-term effects of inhaled iloprost therapy in children with pulmonary arterial hypertension. J Am Coll Cardiol 51:161-169
-
(2008)
J Am Coll Cardiol
, vol.51
, pp. 161-169
-
-
Ivy, D.D.1
Doran, A.K.2
Smith, K.J.3
Mallory Jr., G.B.4
Beghetti, M.5
Barst, R.J.6
Brady, D.7
Law, Y.8
Parker, D.9
Claussen, L.10
Abman, S.H.11
-
40
-
-
84856469571
-
Usefulness of first-line combination therapy with epoprostenol and bosentan in pulmonary arterial hypertension: An observational study
-
Kemp K, Savale L, O'Callaghan DS, Jais X, Montani D, Humbert M, Simonneau G, Sitbon O (2012) Usefulness of first-line combination therapy with epoprostenol and bosentan in pulmonary arterial hypertension: An observational study. J Heart Lung Transplant 31:150-158
-
(2012)
J Heart Lung Transplant
, vol.31
, pp. 150-158
-
-
Kemp, K.1
Savale, L.2
O'Callaghan, D.S.3
Jais, X.4
Montani, D.5
Humbert, M.6
Simonneau, G.7
Sitbon, O.8
-
41
-
-
34247333783
-
How prostacyclin improves cardiac output in right heart failure in conjunction with pulmonary hypertension
-
Kerbaul F, Brimioulle S, Rondelet B, Dewachter C, Hubloue I, Naeije R (2007) How prostacyclin improves cardiac output in right heart failure in conjunction with pulmonary hypertension. Am J Respir Crit Care Med 175:846-850
-
(2007)
Am J Respir Crit Care Med
, vol.175
, pp. 846-850
-
-
Kerbaul, F.1
Brimioulle, S.2
Rondelet, B.3
Dewachter, C.4
Hubloue, I.5
Naeije, R.6
-
42
-
-
84866423254
-
Bloodstream infections in patients with pulmonary arterial hypertension treated with intravenous prostanoids: Insights from the REVEAL REGISTRY(R)
-
Kitterman N, Poms A, Miller DP, Lombardi S, Farber HW, Barst RJ (2012) Bloodstream infections in patients with pulmonary arterial hypertension treated with intravenous prostanoids: Insights from the REVEAL REGISTRY(R). Mayo Clin Proc 87:825-834
-
(2012)
Mayo Clin Proc
, vol.87
, pp. 825-834
-
-
Kitterman, N.1
Poms, A.2
Miller, D.P.3
Lombardi, S.4
Farber, H.W.5
Barst, R.J.6
-
43
-
-
33751294515
-
How should we treat portopulmonary hypertension
-
Krowka MJ, Swanson KL (2006) How should we treat portopulmonary hypertension Eur Respir J 28:466-467
-
(2006)
Eur Respir J
, vol.28
, pp. 466-467
-
-
Krowka, M.J.1
Swanson, K.L.2
-
44
-
-
33745172176
-
Efficacy of long-term subcutaneous treprostinil sodium therapy in pulmonary hypertension
-
Lang I, Gomez-Sanchez M, Kneussl M, Naeije R, Escribano P, Skoro-Sajer N, Vachiery JL (2006) Efficacy of long-term subcutaneous treprostinil sodium therapy in pulmonary hypertension. Chest 129:1636-1643
-
(2006)
Chest
, vol.129
, pp. 1636-1643
-
-
Lang, I.1
Gomez-Sanchez, M.2
Kneussl, M.3
Naeije, R.4
Escribano, P.5
Skoro-Sajer, N.6
Vachiery, J.L.7
-
45
-
-
0036723641
-
Treatment of newborn rats with a VEGF receptor inhibitor causes pulmonary hypertension and abnormal lung structure
-
le Cras TD, Markham NE, Tuder RM, Voelkel NF, Abman SH (2002) Treatment of newborn rats with a VEGF receptor inhibitor causes pulmonary hypertension and abnormal lung structure. Am J Physiol Lung Cell Mol Physiol 283:L555-L562
-
(2002)
Am J Physiol Lung Cell Mol Physiol
, vol.283
, pp. 555-562
-
-
Le Cras, T.D.1
Markham, N.E.2
Tuder, R.M.3
Voelkel, N.F.4
Abman, S.H.5
-
46
-
-
84863298193
-
Peroxisome proliferator-activated receptor-beta/delta, the acute signaling factor in prostacyclin-induced pulmonary vasodilation
-
Li Y, Connolly M, Nagaraj C, Tang B, Balint Z, Popper H, Smolle-Juettner FM, Lindenmann J, Kwapiszewska G, Aaronson PI, Wohlkoenig C, Leithner K, Olschewski H, Olschewski A (2012) Peroxisome proliferator-activated receptor-beta/delta, the acute signaling factor in prostacyclin-induced pulmonary vasodilation. Am J Respir Cell Mol Biol 46:372-379
-
(2012)
Am J Respir Cell Mol Biol
, vol.46
, pp. 372-379
-
-
Li, Y.1
Connolly, M.2
Nagaraj, C.3
Tang, B.4
Balint, Z.5
Popper, H.6
Smolle-Juettner, F.M.7
Lindenmann, J.8
Kwapiszewska, G.9
Aaronson, P.I.10
Wohlkoenig, C.11
Leithner, K.12
Olschewski, H.13
Olschewski, A.14
-
47
-
-
0037126044
-
Survival in primary pulmonary hypertension: The impact of epoprostenol therapy
-
McLaughlin VV, Shillington A, Rich S (2002) Survival in primary pulmonary hypertension: The impact of epoprostenol therapy. Circulation 106:1477-1482
-
(2002)
Circulation
, vol.106
, pp. 1477-1482
-
-
McLaughlin, V.V.1
Shillington, A.2
Rich, S.3
-
48
-
-
33845526777
-
Randomized study of adding inhaled iloprost to existing bosentan in pulmonary arterial hypertension
-
McLaughlin VV, Oudiz RJ, Frost A, Tapson VF, Murali S, Channick RN, Badesch DB, Barst RJ, Hsu HH, Rubin LJ (2006) Randomized study of adding inhaled iloprost to existing bosentan in pulmonary arterial hypertension. Am J Respir Crit Care Med 174:1257-1263
-
(2006)
Am J Respir Crit Care Med
, vol.174
, pp. 1257-1263
-
-
McLaughlin, V.V.1
Oudiz, R.J.2
Frost, A.3
Tapson, V.F.4
Murali, S.5
Channick, R.N.6
Badesch, D.B.7
Barst, R.J.8
Hsu, H.H.9
Rubin, L.J.10
-
49
-
-
77952301237
-
Addition of inhaled treprostinil to oral therapy for pulmonary arterial hypertension: A randomized controlled clinical trial
-
McLaughlin VV, Benza RL, Rubin LJ, Channick RN, Voswinckel R, Tapson VF, Robbins IM, Olschewski H, Rubenfire M, Seeger W (2010) Addition of inhaled treprostinil to oral therapy for pulmonary arterial hypertension: A randomized controlled clinical trial. J Am Coll Cardiol 55:1915-1922
-
(2010)
J Am Coll Cardiol
, vol.55
, pp. 1915-1922
-
-
McLaughlin, V.V.1
Benza, R.L.2
Rubin, L.J.3
Channick, R.N.4
Voswinckel, R.5
Tapson, V.F.6
Robbins, I.M.7
Olschewski, H.8
Rubenfire, M.9
Seeger, W.10
-
50
-
-
1642273850
-
Gene expression profile of the G(s)-coupled prostacyclin receptor in human vascular smooth muscle cells
-
Meyer-Kirchrath J, Debey S, Glandorff C, Kirchrath L, Schror K (2004) Gene expression profile of the G(s)-coupled prostacyclin receptor in human vascular smooth muscle cells. Biochem Pharmacol 67:757-765
-
(2004)
Biochem Pharmacol
, vol.67
, pp. 757-765
-
-
Meyer-Kirchrath, J.1
Debey, S.2
Glandorff, C.3
Kirchrath, L.4
Schror, K.5
-
51
-
-
0017094798
-
An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable substance that inhibits platelet aggregation
-
Moncada S, Gryglewski R, Bunting S, Vane JR (1976) An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable substance that inhibits platelet aggregation. Nature 263:663-665
-
(1976)
Nature
, vol.263
, pp. 663-665
-
-
Moncada, S.1
Gryglewski, R.2
Bunting, S.3
Vane, J.R.4
-
52
-
-
58849085018
-
Pulmonary veno-occlusive disease
-
Montani D, Price LC, Dorfmuller P, Achouh L, Jais X, Yaici A, Sitbon O, Musset D, Simonneau G, HumbertM(2009) Pulmonary veno-occlusive disease. Eur Respir J 33:189-200
-
(2009)
Eur Respir J
, vol.33
, pp. 189-200
-
-
Montani, D.1
Price, L.C.2
Dorfmuller, P.3
Achouh, L.4
Jais, X.5
Yaici, A.6
Sitbon, O.7
Musset, D.8
Simonneau, G.9
Humbert, M.10
-
53
-
-
84869209570
-
Differential effects of selexipag and prostacyclin analogs in rat pulmonary artery
-
Morrison K, Studer R, Ernst R, Haag F, Kauser K, Clozel M (2012) Differential effects of selexipag and prostacyclin analogs in rat pulmonary artery. J Pharmacol Exp Ther 343:547-555
-
(2012)
J Pharmacol Exp Ther
, vol.343
, pp. 547-555
-
-
Morrison, K.1
Studer, R.2
Ernst, R.3
Haag, F.4
Kauser, K.5
Clozel, M.6
-
54
-
-
84872202945
-
Src tyrosine kinase is crucial for potassium channel function in human pulmonary arteries
-
Nagaraj C, Tang B, Balint Z, Wygrecka M, Hrzenjak A, Kwapiszewska G, Stacher E, Lindenmann J, Weir EK, Olschewski H, Olschewski A (2012) Src tyrosine kinase is crucial for potassium channel function in human pulmonary arteries. Eur Respir J 41(1):85-95
-
(2012)
Eur Respir J
, vol.41
, Issue.1
, pp. 85-95
-
-
Nagaraj, C.1
Tang, B.2
Balint, Z.3
Wygrecka, M.4
Hrzenjak, A.5
Kwapiszewska, G.6
Stacher, E.7
Lindenmann, J.8
Weir, E.K.9
Olschewski, H.10
Olschewski, A.11
-
55
-
-
0037687432
-
Prognostic factors for survival in HIV-associated pulmonary arterial hypertension
-
Nunes H, Humbert M, Sitbon O, Morse JH, Deng Z, Knowles JA, Le Gall C, Parent F, Garcia G, Herve P, Barst RJ, Simonneau G (2003) Prognostic factors for survival in HIV-associated pulmonary arterial hypertension. Am J Respir Crit Care Med 167:1433-1439
-
(2003)
Am J Respir Crit Care Med
, vol.167
, pp. 1433-1439
-
-
Nunes, H.1
Humbert, M.2
Sitbon, O.3
Morse, J.H.4
Deng, Z.5
Knowles, J.A.6
Le Gall, C.7
Parent, F.8
Garcia, G.9
Herve, P.10
Barst, R.J.11
Simonneau, G.12
-
56
-
-
0018869114
-
Effects of intravenous infusion of prostacyclin (PGI2) in man
-
O'Grady J, Warrington S, Moti MJ, Bunting S, Flower R, Fowle AS, Higgs EA, Moncada S (1980) Effects of intravenous infusion of prostacyclin (PGI2) in man. Prostaglandins 19:319-332
-
(1980)
Prostaglandins
, vol.19
, pp. 319-332
-
-
O'Grady, J.1
Warrington, S.2
Moti, M.J.3
Bunting, S.4
Flower, R.5
Fowle, A.S.6
Higgs, E.A.7
Moncada, S.8
-
58
-
-
0029993602
-
Aerosolized prostacyclin and iloprost in severe pulmonary hypertension
-
Olschewski H, Walmrath D, Schermuly R, Ghofrani A, Grimminger F, Seeger W (1996) Aerosolized prostacyclin and iloprost in severe pulmonary hypertension. Ann Intern Med 124:820-824
-
(1996)
Ann Intern Med
, vol.124
, pp. 820-824
-
-
Olschewski, H.1
Walmrath, D.2
Schermuly, R.3
Ghofrani, A.4
Grimminger, F.5
Seeger, W.6
-
59
-
-
0032810972
-
Inhaled prostacyclin and iloprost in severe pulmonary hypertension secondary to lung fibrosis
-
Olschewski H, Ghofrani HA, Walmrath D, Schermuly R, Temmesfeld-Wollbruck B, Grimminger F, Seeger W (1999) Inhaled prostacyclin and iloprost in severe pulmonary hypertension secondary to lung fibrosis. Am J Respir Crit Care Med 160:600-607
-
(1999)
Am J Respir Crit Care Med
, vol.160
, pp. 600-607
-
-
Olschewski, H.1
Ghofrani, H.A.2
Walmrath, D.3
Schermuly, R.4
Temmesfeld-Wollbruck, B.5
Grimminger, F.6
Seeger, W.7
-
60
-
-
0034696634
-
Inhaled iloprost to treat severe pulmonary hypertension. An uncontrolled trial
-
German PPH Study Group
-
Olschewski H, Ghofrani HA, Schmehl T, Winkler J, Wilkens H, Hoper MM, Behr J, Kleber FX, Seeger W (2000) Inhaled iloprost to treat severe pulmonary hypertension. An uncontrolled trial. German PPH Study Group. Ann Intern Med 132:435-443
-
(2000)
Ann Intern Med
, vol.132
, pp. 435-443
-
-
Olschewski, H.1
Ghofrani, H.A.2
Schmehl, T.3
Winkler, J.4
Wilkens, H.5
Hoper, M.M.6
Behr, J.7
Kleber, F.X.8
Seeger, W.9
-
61
-
-
0035543338
-
Cellular pathophysiology and therapy of pulmonary hypertension
-
Olschewski H, Rose F, Grunig E, Ghofrani HA, Walmrath D, Schulz R, Schermuly R, Grimminger F, Seeger W (2001a) Cellular pathophysiology and therapy of pulmonary hypertension. J Lab Clin Med 138:367-377
-
(2001)
J Lab Clin Med
, vol.138
, pp. 367-377
-
-
Olschewski, H.1
Rose, F.2
Grunig, E.3
Ghofrani, H.A.4
Walmrath, D.5
Schulz, R.6
Schermuly, R.7
Grimminger, F.8
Seeger, W.9
-
62
-
-
0035174580
-
Physiologic basis for the treatment of pulmonary hypertension
-
Olschewski H, Olschewski A, Rose F, Schermuly R, Schutte H, Weissmann N, Seeger W, Grimminger F (2001b) Physiologic basis for the treatment of pulmonary hypertension. J Lab Clin Med 138:287-297
-
(2001)
J Lab Clin Med
, vol.138
, pp. 287-297
-
-
Olschewski, H.1
Olschewski, A.2
Rose, F.3
Schermuly, R.4
Schutte, H.5
Weissmann, N.6
Seeger, W.7
Grimminger, F.8
-
63
-
-
0036682273
-
Inhaled iloprost for severe pulmonary hypertension
-
Olschewski H, Simonneau G, Galie N, Higenbottam T, Naeije R, Rubin LJ, Nikkho S, Speich R, Hoeper MM, Behr J, Winkler J, Sitbon O, Popov W, Ghofrani HA, Manes A, Kiely DG, Ewert R, Meyer A, Corris PA, Delcroix M, Gomez-Sanchez M, Siedentop H, SeegerW(2002) Inhaled iloprost for severe pulmonary hypertension. N Engl J Med 347:322-329
-
(2002)
N Engl J Med
, vol.347
, pp. 322-329
-
-
Olschewski, H.1
Simonneau, G.2
Galie, N.3
Higenbottam, T.4
Naeije, R.5
Rubin, L.J.6
Nikkho, S.7
Speich, R.8
Hoeper, M.M.9
Behr, J.10
Winkler, J.11
Sitbon, O.12
Popov, W.13
Ghofrani, H.A.14
Manes, A.15
Kiely, D.G.16
Ewert, R.17
Meyer, A.18
Corris, P.A.19
Delcroix, M.20
Gomez-Sanchez, M.21
Siedentop, H.22
Seeger, W.23
more..
-
64
-
-
0142074258
-
Pharmacodynamics and pharmacokinetics of inhaled iloprost, aerosolized by three different devices, in severe pulmonary hypertension
-
Olschewski H, Rohde B, Behr J, Ewert R, Gessler T, Ghofrani HA, Schmehl T (2003) Pharmacodynamics and pharmacokinetics of inhaled iloprost, aerosolized by three different devices, in severe pulmonary hypertension. Chest 124:1294-1304
-
(2003)
Chest
, vol.124
, pp. 1294-1304
-
-
Olschewski, H.1
Rohde, B.2
Behr, J.3
Ewert, R.4
Gessler, T.5
Ghofrani, H.A.6
Schmehl, T.7
-
65
-
-
33646816053
-
Impact of TASK-1 in human pulmonary artery smooth muscle cells
-
Olschewski A, Li Y, Tang B, Hanze J, Eul B, Bohle RM, Wilhelm J, Morty RE, Brau ME, Weir EK, Kwapiszewska G, Klepetko W, Seeger W, Olschewski H (2006) Impact of TASK-1 in human pulmonary artery smooth muscle cells. Circ Res 98:1072-1080
-
(2006)
Circ Res
, vol.98
, pp. 1072-1080
-
-
Olschewski, A.1
Li, Y.2
Tang, B.3
Hanze, J.4
Eul, B.5
Bohle, R.M.6
Wilhelm, J.7
Morty, R.E.8
Brau, M.E.9
Weir, E.K.10
Kwapiszewska, G.11
Klepetko, W.12
Seeger, W.13
Olschewski, H.14
-
66
-
-
77951621266
-
Long-term therapy with inhaled iloprost in patients with pulmonary hypertension
-
Olschewski H, Hoeper MM, Behr J, Ewert R, Meyer A, Borst MM, Winkler J, Pfeifer M, Wilkens H, Ghofrani HA, Nikkho S, SeegerW(2010) Long-term therapy with inhaled iloprost in patients with pulmonary hypertension. Respir Med 104:731-740
-
(2010)
Respir Med
, vol.104
, pp. 731-740
-
-
Olschewski, H.1
Hoeper, M.M.2
Behr, J.3
Ewert, R.4
Meyer, A.5
Borst, M.M.6
Winkler, J.7
Pfeifer, M.8
Wilkens, H.9
Ghofrani, H.A.10
Nikkho, S.11
Seeger, W.12
-
67
-
-
84868212644
-
Safety and efficacy of transition from systemic prostanoids to inhaled treprostinil in pulmonary arterial hypertension
-
Perez VA, Rosenzweig E, Rubin LJ, Poch D, Bajwa A, Park M, Jain M, Bourge RC, Kudelko K, Spiekerkoetter E, Liu J, Hsi A, Zamanian RT (2012) Safety and efficacy of transition from systemic prostanoids to inhaled treprostinil in pulmonary arterial hypertension. Am J Cardiol 110(10):1546-1550
-
(2012)
Am J Cardiol
, vol.110
, Issue.10
, pp. 1546-1550
-
-
Perez, V.A.1
Rosenzweig, E.2
Rubin, L.J.3
Poch, D.4
Bajwa, A.5
Park, M.6
Jain, M.7
Bourge, R.C.8
Kudelko, K.9
Spiekerkoetter, E.10
Liu, J.11
Hsi, A.12
Zamanian, R.T.13
-
68
-
-
1542328876
-
Comparative analysis of the in vivo angiogenic properties of stable prostacyclin analogs: A possible role for peroxisome proliferator-activated receptors
-
Pola R, Gaetani E, Flex A, Aprahamian TR, Bosch-Marce M, Losordo DW, Smith RC, Pola P (2004) Comparative analysis of the in vivo angiogenic properties of stable prostacyclin analogs: A possible role for peroxisome proliferator-activated receptors. J Mol Cell Cardiol 36:363-370
-
(2004)
J Mol Cell Cardiol
, vol.36
, pp. 363-370
-
-
Pola, R.1
Gaetani, E.2
Flex, A.3
Aprahamian, T.R.4
Bosch-Marce, M.5
Losordo, D.W.6
Smith, R.C.7
Pola, P.8
-
69
-
-
30744436109
-
Occult alveolar haemorrhage in pulmonary veno-occlusive disease
-
Rabiller A, Jais X, Hamid A, Resten A, Parent F, Haque R, Capron F, Sitbon O, Simonneau G, Humbert M (2006) Occult alveolar haemorrhage in pulmonary veno-occlusive disease. Eur Respir J 27:108-113
-
(2006)
Eur Respir J
, vol.27
, pp. 108-113
-
-
Rabiller, A.1
Jais, X.2
Hamid, A.3
Resten, A.4
Parent, F.5
Haque, R.6
Capron, F.7
Sitbon, O.8
Simonneau, G.9
Humbert, M.10
-
70
-
-
0031939716
-
Prostaglandins promote and block adipogenesis through opposing effects on peroxisome proliferator-activated receptor gamma
-
Reginato MJ, Krakow SL, Bailey ST, Lazar MA (1998) Prostaglandins promote and block adipogenesis through opposing effects on peroxisome proliferator-activated receptor gamma. J Biol Chem 273:1855-1858
-
(1998)
J Biol Chem
, vol.273
, pp. 1855-1858
-
-
Reginato, M.J.1
Krakow, S.L.2
Bailey, S.T.3
Lazar, M.A.4
-
71
-
-
33750098824
-
Sildenafil treatment for portopulmonary hypertension
-
Reichenberger F, Voswinckel R, Steveling E, Enke B, Kreckel A, Olschewski H, Grimminger F, Seeger W, Ghofrani HA (2006) Sildenafil treatment for portopulmonary hypertension. Eur Respir J 28:563-567
-
(2006)
Eur Respir J
, vol.28
, pp. 563-567
-
-
Reichenberger, F.1
Voswinckel, R.2
Steveling, E.3
Enke, B.4
Kreckel, A.5
Olschewski, H.6
Grimminger, F.7
Seeger, W.8
Ghofrani, H.A.9
-
72
-
-
0031765160
-
A survey of diagnostic practices and the use of epoprostenol in patients with primary pulmonary hypertension
-
Robbins IM, Christman BW, Newman JH, Matlock R, Loyd JE (1998) A survey of diagnostic practices and the use of epoprostenol in patients with primary pulmonary hypertension. Chest 114:1269-1275
-
(1998)
Chest
, vol.114
, pp. 1269-1275
-
-
Robbins, I.M.1
Christman, B.W.2
Newman, J.H.3
Matlock, R.4
Loyd, J.E.5
-
73
-
-
0346272799
-
Increased neutrophil mediator release in patients with pulmonary hypertension-suppression by inhaled iloprost
-
Rose F, Hattar K, Gakisch S, Grimminger F, Olschewski H, Seeger W, Tschuschner A, Schermuly RT, Weissmann N, Hanze J, Sibelius U, Ghofrani HA (2003) Increased neutrophil mediator release in patients with pulmonary hypertension-suppression by inhaled iloprost. Thromb Haemost 90:1141-1149
-
(2003)
Thromb Haemost
, vol.90
, pp. 1141-1149
-
-
Rose, F.1
Hattar, K.2
Gakisch, S.3
Grimminger, F.4
Olschewski, H.5
Seeger, W.6
Tschuschner, A.7
Schermuly, R.T.8
Weissmann, N.9
Hanze, J.10
Sibelius, U.11
Ghofrani, H.A.12
-
74
-
-
0033551155
-
Long-term prostacyclin for pulmonary hypertension with associated congenital heart defects
-
Rosenzweig EB, Kerstein D, Barst RJ (1999) Long-term prostacyclin for pulmonary hypertension with associated congenital heart defects. Circulation 99:1858-1865
-
(1999)
Circulation
, vol.99
, pp. 1858-1865
-
-
Rosenzweig, E.B.1
Kerstein, D.2
Barst, R.J.3
-
75
-
-
0019985926
-
Prostacyclin-induced acute pulmonary vasodilation in primary pulmonary hypertension
-
Rubin LJ, Groves BM, Reeves JT, Frosolono M, Handel F, Cato AE (1982) Prostacyclin-induced acute pulmonary vasodilation in primary pulmonary hypertension. Circulation 66:334-338
-
(1982)
Circulation
, vol.66
, pp. 334-338
-
-
Rubin, L.J.1
Groves, B.M.2
Reeves, J.T.3
Frosolono, M.4
Handel, F.5
Cato, A.E.6
-
76
-
-
0037086133
-
Continuous subcutaneous infusion of treprostinil, a prostacyclin analogue, in patients with pulmonary arterial hypertension. A double-blind, randomized, placebo-controlled trial
-
Simonneau G, Barst RJ, Galie N, Naeije R, Rich S, Bourge RC, Keogh A, Oudiz R, Frost A, Blackburn SD, Crow JW, Rubin LJ (2002) Continuous subcutaneous infusion of treprostinil, a prostacyclin analogue, in patients with pulmonary arterial hypertension. A double-blind, randomized, placebo-controlled trial. Am J Respir Crit Care Med 165:800-804
-
(2002)
Am J Respir Crit Care Med
, vol.165
, pp. 800-804
-
-
Simonneau, G.1
Barst, R.J.2
Galie, N.3
Naeije, R.4
Rich, S.5
Bourge, R.C.6
Keogh, A.7
Oudiz, R.8
Frost, A.9
Blackburn, S.D.10
Crow, J.W.11
Rubin, L.J.12
-
77
-
-
54549125950
-
Addition of sildenafil to long-term intravenous epoprostenol therapy in patients with pulmonary arterial hypertension: A randomized trial
-
Simonneau G, Rubin LJ, Galie N, Barst RJ, Fleming TR, Frost AE, Engel PJ, Kramer MR, Burgess G, Collings L, Cossons N, Sitbon O, Badesch DB (2008) Addition of sildenafil to long-term intravenous epoprostenol therapy in patients with pulmonary arterial hypertension: A randomized trial. Ann Intern Med 149:521-530
-
(2008)
Ann Intern Med
, vol.149
, pp. 521-530
-
-
Simonneau, G.1
Rubin, L.J.2
Galie, N.3
Barst, R.J.4
Fleming, T.R.5
Frost, A.E.6
Engel, P.J.7
Kramer, M.R.8
Burgess, G.9
Collings, L.10
Cossons, N.11
Sitbon, O.12
Badesch, D.B.13
-
78
-
-
84863528040
-
Selexipag: An oral, selective prostacyclin receptor agonist for the treatment of pulmonary arterial hypertension
-
Simonneau G, Torbicki A, Hoeper MM, Delcroix M, Karlocai K, Galie N, Degano B, Bonderman D, Kurzyna M, Efficace M, Giorgino R, Lang IM (2012) Selexipag: An oral, selective prostacyclin receptor agonist for the treatment of pulmonary arterial hypertension. Eur Respir J 40:874-880
-
(2012)
Eur Respir J
, vol.40
, pp. 874-880
-
-
Simonneau, G.1
Torbicki, A.2
Hoeper, M.M.3
Delcroix, M.4
Karlocai, K.5
Galie, N.6
Degano, B.7
Bonderman, D.8
Kurzyna, M.9
Efficace, M.10
Giorgino, R.11
Lang, I.M.12
-
79
-
-
0037151645
-
Long-term intravenous epoprostenol infusion in primary pulmonary hypertension: Prognostic factors and survival
-
Sitbon O, Humbert M, Nunes H, Parent F, Garcia G, Herve P, Rainisio M, Simonneau G (2002) Long-term intravenous epoprostenol infusion in primary pulmonary hypertension: Prognostic factors and survival. J Am Coll Cardiol 40:780-788
-
(2002)
J Am Coll Cardiol
, vol.40
, pp. 780-788
-
-
Sitbon, O.1
Humbert, M.2
Nunes, H.3
Parent, F.4
Garcia, G.5
Herve, P.6
Rainisio, M.7
Simonneau, G.8
-
80
-
-
33846598425
-
Rapid switch from intravenous epoprostenol to intravenous treprostinil in patients with pulmonary arterial hypertension
-
Sitbon O, Manes A, Jais X, Pallazini M, Humbert M, Presotto L, Paillette L, Zaccardelli D, Davis G, Jeffs R, Simonneau G, Galie N (2007) Rapid switch from intravenous epoprostenol to intravenous treprostinil in patients with pulmonary arterial hypertension. J Cardiovasc Pharmacol 49:1-5
-
(2007)
J Cardiovasc Pharmacol
, vol.49
, pp. 1-5
-
-
Sitbon, O.1
Manes, A.2
Jais, X.3
Pallazini, M.4
Humbert, M.5
Presotto, L.6
Paillette, L.7
Zaccardelli, D.8
Davis, G.9
Jeffs, R.10
Simonneau, G.11
Galie, N.12
-
81
-
-
84864522564
-
Modern age pathology of pulmonary arterial hypertension
-
Stacher E, Graham BB, Hunt JM, Gandjeva A, Groshong SD, McLaughlin VV, Jessup M, Grizzle WE, Aldred MA, Cool CD, Tuder RM (2012) Modern age pathology of pulmonary arterial hypertension. Am J Respir Crit Care Med 186:261-272
-
(2012)
Am J Respir Crit Care Med
, vol.186
, pp. 261-272
-
-
Stacher, E.1
Graham, B.B.2
Hunt, J.M.3
Gandjeva, A.4
Groshong, S.D.5
McLaughlin, V.V.6
Jessup, M.7
Grizzle, W.E.8
Aldred, M.A.9
Cool, C.D.10
Tuder, R.M.11
-
82
-
-
1642276214
-
Induction of hyaluronic acid synthase 2 (HAS2) in human vascular smooth muscle cells by vasodilatory prostaglandins
-
Sussmann M, Sarbia M, Meyer-Kirchrath J, Nusing RM, Schror K, Fischer JW (2004) Induction of hyaluronic acid synthase 2 (HAS2) in human vascular smooth muscle cells by vasodilatory prostaglandins. Circ Res 94:592-600
-
(2004)
Circ Res
, vol.94
, pp. 592-600
-
-
Sussmann, M.1
Sarbia, M.2
Meyer-Kirchrath, J.3
Nusing, R.M.4
Schror, K.5
Fischer, J.W.6
-
83
-
-
70349084966
-
Endothelin-1 inhibits background two-pore domain channel TASK-1 in primary human pulmonary artery smooth muscle cells
-
Tang B, Li Y, Nagaraj C, Morty RE, Gabor S, Stacher E, Voswinckel R, Weissmann N, Leithner K, Olschewski H, Olschewski A (2009) Endothelin-1 inhibits background two-pore domain channel TASK-1 in primary human pulmonary artery smooth muscle cells. Am J Respir Cell Mol Biol 41:476-483
-
(2009)
Am J Respir Cell Mol Biol
, vol.41
, pp. 476-483
-
-
Tang, B.1
Li, Y.2
Nagaraj, C.3
Morty, R.E.4
Gabor, S.5
Stacher, E.6
Voswinckel, R.7
Weissmann, N.8
Leithner, K.9
Olschewski, H.10
Olschewski, A.11
-
84
-
-
0035130107
-
Inhibition of the VEGF receptor 2 combined with chronic hypoxia causes cell death-dependent pulmonary endothelial cell proliferation and severe pulmonary hypertension
-
Taraseviciene-Stewart L, Kasahara Y, Alger L, Hirth P, Mc MG, Waltenberger J, Voelkel NF, Tuder RM (2001) Inhibition of the VEGF receptor 2 combined with chronic hypoxia causes cell death-dependent pulmonary endothelial cell proliferation and severe pulmonary hypertension. FASEB J 15:427-438
-
(2001)
FASEB J
, vol.15
, pp. 427-438
-
-
Taraseviciene-Stewart, L.1
Kasahara, Y.2
Alger, L.3
Hirth, P.4
Mc, M.G.5
Waltenberger, J.6
Voelkel, N.F.7
Tuder, R.M.8
-
85
-
-
33749537060
-
Favorable effects of inhaled treprostinil in severe pulmonary hypertension: Results from randomized controlled pilot studies
-
Voswinckel R, Enke B, Reichenberger F, Kohstall M, Kreckel A, Krick S, Gall H, Gessler T, Schmehl T, Ghofrani HA, Schermuly RT, Grimminger F, Rubin LJ, Seeger W, Olschewski H (2006) Favorable effects of inhaled treprostinil in severe pulmonary hypertension: Results from randomized controlled pilot studies. J Am Coll Cardiol 48:1672-1681
-
(2006)
J Am Coll Cardiol
, vol.48
, pp. 1672-1681
-
-
Voswinckel, R.1
Enke, B.2
Reichenberger, F.3
Kohstall, M.4
Kreckel, A.5
Krick, S.6
Gall, H.7
Gessler, T.8
Schmehl, T.9
Ghofrani, H.A.10
Schermuly, R.T.11
Grimminger, F.12
Rubin, L.J.13
Seeger, W.14
Olschewski, H.15
-
86
-
-
50849116416
-
Acute effects of the combination of sildenafil and inhaled treprostinil on haemodynamics and gas exchange in pulmonary hypertension
-
Voswinckel R, Reichenberger F, Enke B, Kreckel A, Krick S, Gall H, Schermuly RT, Grimminger F, Rubin LJ, Olschewski H, Seeger W, Ghofrani HA (2008) Acute effects of the combination of sildenafil and inhaled treprostinil on haemodynamics and gas exchange in pulmonary hypertension. Pulm Pharmacol Ther 25:824-832
-
(2008)
Pulm Pharmacol Ther
, vol.25
, pp. 824-832
-
-
Voswinckel, R.1
Reichenberger, F.2
Enke, B.3
Kreckel, A.4
Krick, S.5
Gall, H.6
Schermuly, R.T.7
Grimminger, F.8
Rubin, L.J.9
Olschewski, H.10
Seeger, W.11
Ghofrani, H.A.12
-
87
-
-
58349110755
-
Metered dose inhaler delivery of treprostinil for the treatment of pulmonary hypertension
-
Voswinckel R, Reichenberger F, Gall H, Schmehl T, Gessler T, Schermuly RT, Grimminger F, Rubin LJ, Seeger W, Ghofrani HA, Olschewski H (2009) Metered dose inhaler delivery of treprostinil for the treatment of pulmonary hypertension. Pulm Pharmacol Ther 22:50-56
-
(2009)
Pulm Pharmacol Ther
, vol.22
, pp. 50-56
-
-
Voswinckel, R.1
Reichenberger, F.2
Gall, H.3
Schmehl, T.4
Gessler, T.5
Schermuly, R.T.6
Grimminger, F.7
Rubin, L.J.8
Seeger, W.9
Ghofrani, H.A.10
Olschewski, H.11
-
88
-
-
0027366628
-
Aerosolised prostacyclin in adult respiratory distress syndrome
-
Walmrath D, Schneider T, Pilch J, Grimminger F, Seeger W (1993) Aerosolised prostacyclin in adult respiratory distress syndrome. Lancet 342:961-962
-
(1993)
Lancet
, vol.342
, pp. 961-962
-
-
Walmrath, D.1
Schneider, T.2
Pilch, J.3
Grimminger, F.4
Seeger, W.5
-
89
-
-
0029880173
-
Direct comparison of inhaled nitric oxide and aerosolized prostacyclin in acute respiratory distress syndrome
-
Walmrath D, Schneider T, Schermuly R, Olschewski H, Grimminger F, Seeger W (1996) Direct comparison of inhaled nitric oxide and aerosolized prostacyclin in acute respiratory distress syndrome. Am J Respir Crit Care Med 153:991-996
-
(1996)
Am J Respir Crit Care Med
, vol.153
, pp. 991-996
-
-
Walmrath, D.1
Schneider, T.2
Schermuly, R.3
Olschewski, H.4
Grimminger, F.5
Seeger, W.6
-
90
-
-
0024804879
-
The acute administration of vasodilators in primary pulmonary hypertension. Experience from the National Institutes of Health Registry on Primary Pulmonary Hypertension
-
Weir EK, Rubin LJ, Ayres SM, Bergofsky EH, Brundage BH, Detre KM, Elliott CG, Fishman AP, Goldring RM, Groves BM (1989) The acute administration of vasodilators in primary pulmonary hypertension. Experience from the National Institutes of Health Registry on Primary Pulmonary Hypertension. Am Rev Respir Dis 140:1623-1630
-
(1989)
Am Rev Respir Dis
, vol.140
, pp. 1623-1630
-
-
Weir, E.K.1
Rubin, L.J.2
Ayres, S.M.3
Bergofsky, E.H.4
Brundage, B.H.5
Detre, K.M.6
Elliott, C.G.7
Fishman, A.P.8
Goldring, R.M.9
Groves, B.M.10
-
91
-
-
0038391490
-
Multiple signalling options for prostacyclin
-
Wise H (2003) Multiple signalling options for prostacyclin. Acta Pharmacol Sin 24:625-630
-
(2003)
Acta Pharmacol Sin
, vol.24
, pp. 625-630
-
-
Wise, H.1
|