Inhibition of LINE-1 retrotransposon-encoded reverse transcriptase modulates the expression of cell differentiation genes in breast cancer cells

Breast Cancer Research and Treatment

Volumn 143, Issue 2, 2014, Pages 239-253

  Patnala, Radhika ^a,c   Lee, Sung Hun ^a,d   Dahlstrom, Jane E ^a,b   Ohms, Stephen ^a   Chen, Long ^a   Dheen, S Thameem ^c   Rangasamy, Danny ^a  

^a Biology and Environment   (Australia)

^b CANBERRA HOSPITAL   (Australia)

^c NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^d UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

Breast cancer cells; Cell growth; Differentiation; Efavirenz; Gene expression; LINE 1; Retrotransposons

Indexed keywords

EFAVIRENZ; MESSENGER RNA; RNA DIRECTED DNA POLYMERASE; BENZOXAZINE DERIVATIVE; RNA DIRECTED DNA POLYMERASE INHIBITOR;

ARTICLE; BREAST CANCER; CANCER CELL; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL STRUCTURE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE REPRESSION; HUMAN; HUMAN CELL; LONG INTERSPERSED ELEMENT 1; PRIORITY JOURNAL; PROTEIN EXPRESSION; RETROPOSON; UPREGULATION; BIOSYNTHESIS; BREAST TUMOR; CELL CYCLE; DRUG EFFECTS; FEMALE; GENETICS; LONG INTERSPERSED REPEAT; MCF 7 CELL LINE; PSEUDOPODIUM; TUMOR CELL LINE;

BENZOXAZINES; BREAST NEOPLASMS; CELL CYCLE; CELL DIFFERENTIATION; CELL LINE, TUMOR; CELL PROLIFERATION; FEMALE; GENE EXPRESSION PROFILING; HUMANS; LONG INTERSPERSED NUCLEOTIDE ELEMENTS; MCF-7 CELLS; PSEUDOPODIA; REVERSE TRANSCRIPTASE INHIBITORS; RNA, MESSENGER; RNA-DIRECTED DNA POLYMERASE;

EID: 84893093139     PISSN: 01676806     EISSN: 15737217     Source Type: Journal    
DOI: 10.1007/s10549-013-2812-7     Document Type: Article

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