메뉴 건너뛰기




Volumn 171, Issue 4, 2014, Pages 849-858

Pancreatic cancer

Author keywords

chemotherapy resistance; gemcitabine; midkine; Notch; pancreatic cancer; PDAC; therapy; tumour

Indexed keywords

FIBROBLAST GROWTH FACTOR; FLUOROURACIL; GEMCITABINE; MIDKINE; MITOGEN ACTIVATED PROTEIN KINASE; NOTCH2 RECEPTOR; SONIC HEDGEHOG PROTEIN; STRESS ACTIVATED PROTEIN KINASE; TRANSFORMING GROWTH FACTOR BETA; WNT PROTEIN;

EID: 84893068657     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/bph.12401     Document Type: Review
Times cited : (64)

References (87)
  • 1
    • 0024292722 scopus 로고
    • Most human carcinomas of the exocrine pancreas contain mutant c-K-ras genes
    • Almoguera C, Shibata D, Forrester K, Martin J, Arnheim N, Perucho M, (1988). Most human carcinomas of the exocrine pancreas contain mutant c-K-ras genes. Cell 53: 549-554.
    • (1988) Cell , vol.53 , pp. 549-554
    • Almoguera, C.1    Shibata, D.2    Forrester, K.3    Martin, J.4    Arnheim, N.5    Perucho, M.6
  • 2
    • 34247392005 scopus 로고    scopus 로고
    • Drosophila follicle cells are patterned by multiple levels of Notch signaling and antagonism between the Notch and JAK/STAT pathways
    • Assa-Kunik E, Torres IL, Schejter ED, Johnston DS, Shilo BZ, (2007). Drosophila follicle cells are patterned by multiple levels of Notch signaling and antagonism between the Notch and JAK/STAT pathways. Development 134: 1161-1169.
    • (2007) Development , vol.134 , pp. 1161-1169
    • Assa-Kunik, E.1    Torres, I.L.2    Schejter, E.D.3    Johnston, D.S.4    Shilo, B.Z.5
  • 3
    • 0035374620 scopus 로고    scopus 로고
    • Tyrosine-phosphorylated low density lipoprotein receptor-related protein 1 (Lrp1) associates with the adaptor protein SHC in SRC- transformed cells
    • Barnes H, Larsen B, Tyers M, van Der Geer P, (2001). Tyrosine- phosphorylated low density lipoprotein receptor-related protein 1 (Lrp1) associates with the adaptor protein SHC in SRC- transformed cells. J Biol Chem 276: 19119-19125.
    • (2001) J Biol Chem , vol.276 , pp. 19119-19125
    • Barnes, H.1    Larsen, B.2    Tyers, M.3    Van Der Geer, P.4
  • 4
    • 34547903586 scopus 로고    scopus 로고
    • Validation of the 6th edition AJCC Pancreatic Cancer Staging System: Report from the National Cancer Database
    • Bilimoria KY, Bentrem DJ, Ko CY, Ritchey J, Stewart AK, Winchester DP, et al. (2007). Validation of the 6th edition AJCC Pancreatic Cancer Staging System: report from the National Cancer Database. Cancer 110: 738-744.
    • (2007) Cancer , vol.110 , pp. 738-744
    • Bilimoria, K.Y.1    Bentrem, D.J.2    Ko, C.Y.3    Ritchey, J.4    Stewart, A.K.5    Winchester, D.P.6
  • 5
    • 0035313042 scopus 로고    scopus 로고
    • The alpha 4 beta 1 (very late antigen (VLA)-4, CD49d/CD29) and alpha 5 beta 1 (VLA-5, CD49e/CD29) integrins mediate beta 2 (CD11/CD18) integrin-independent neutrophil recruitment to endotoxin-induced lung inflammation
    • Burns JA, Issekutz TB, Yagita H, Issekutz AC, (2001). The alpha 4 beta 1 (very late antigen (VLA)-4, CD49d/CD29) and alpha 5 beta 1 (VLA-5, CD49e/CD29) integrins mediate beta 2 (CD11/CD18) integrin-independent neutrophil recruitment to endotoxin-induced lung inflammation. J Immunol 166: 4644-4649.
    • (2001) J Immunol , vol.166 , pp. 4644-4649
    • Burns, J.A.1    Issekutz, T.B.2    Yagita, H.3    Issekutz, A.C.4
  • 6
    • 8244254377 scopus 로고    scopus 로고
    • Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: A randomized trial
    • Burris HA III, Moore MJ, Andersen J, Green MR, Rothenberg ML, Modiano MR, et al. (1997). Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: a randomized trial. J Clin Oncol 15: 2403-2413.
    • (1997) J Clin Oncol , vol.15 , pp. 2403-2413
    • Burris III, H.A.1    Moore, M.J.2    Andersen, J.3    Green, M.R.4    Rothenberg, M.L.5    Modiano, M.R.6
  • 7
    • 0029125820 scopus 로고
    • K-ras mutation and pancreatic adenocarcinoma
    • Caldas C, Kern SE, (1995). K-ras mutation and pancreatic adenocarcinoma. Int J Pancreatol 18: 1-6.
    • (1995) Int J Pancreatol , vol.18 , pp. 1-6
    • Caldas, C.1    Kern, S.E.2
  • 8
    • 84873341409 scopus 로고    scopus 로고
    • Deciphering the mechanisms of tumorigenesis in human pancreatic ductal epithelial cells
    • Chang Z, Li Z, Wang X, Kang Y, Yuan Y, Niu J, et al. (2013). Deciphering the mechanisms of tumorigenesis in human pancreatic ductal epithelial cells. Clin Cancer Res 19: 549-559.
    • (2013) Clin Cancer Res , vol.19 , pp. 549-559
    • Chang, Z.1    Li, Z.2    Wang, X.3    Kang, Y.4    Yuan, Y.5    Niu, J.6
  • 9
    • 84863012865 scopus 로고    scopus 로고
    • Oncogenic Kras is required for both the initiation and maintenance of pancreatic cancer in mice
    • Collins MA, Bednar F, Zhang Y, Brisset JC, Galbán S, Galbán CJ, et al. (2012). Oncogenic Kras is required for both the initiation and maintenance of pancreatic cancer in mice. J Clin Invest 122: 639-653.
    • (2012) J Clin Invest , vol.122 , pp. 639-653
    • Collins, M.A.1    Bednar, F.2    Zhang, Y.3    Brisset, J.C.4    Galbán, S.5    Galbán, C.J.6
  • 10
    • 84879639998 scopus 로고    scopus 로고
    • Classification, morphology and molecular pathology of premalignant lesions of the pancreas
    • Cooper CL, O'Toole SA, Kench JG, (2013). Classification, morphology and molecular pathology of premalignant lesions of the pancreas. Pathology 45: 286-304.
    • (2013) Pathology , vol.45 , pp. 286-304
    • Cooper, C.L.1    O'Toole, S.A.2    Kench, J.G.3
  • 11
    • 67651180835 scopus 로고    scopus 로고
    • In vitro and in vivo suppression of hepatocellular carcinoma growth by midkine-Antisense oligonucleotide-loaded nanoparticles
    • Dai LC, Yao X, Wang X, Niu SQ, Zhou LF, Fu FF, et al. (2009). In vitro and in vivo suppression of hepatocellular carcinoma growth by midkine-Antisense oligonucleotide-loaded nanoparticles. World J Gastroenterol 15: 1966-1972.
    • (2009) World J Gastroenterol , vol.15 , pp. 1966-1972
    • Dai, L.C.1    Yao, X.2    Wang, X.3    Niu, S.Q.4    Zhou, L.F.5    Fu, F.F.6
  • 12
    • 59249090274 scopus 로고    scopus 로고
    • Midkine translocated to nucleoli and involved in carcinogenesis
    • Dai L-C, (2009). Midkine translocated to nucleoli and involved in carcinogenesis. World J Gastroenterol 15: 412-416.
    • (2009) World J Gastroenterol , vol.15 , pp. 412-416
    • Dai, L.-C.1
  • 13
    • 84876437832 scopus 로고    scopus 로고
    • Selective requirement of PI3K/PDK1 signaling for Kras oncogene-driven pancreatic cell plasticity and cancer
    • Eser S, Reiff N, Messer M, Seidler B, Gottschalk K, Dobler M, et al. (2013). Selective requirement of PI3K/PDK1 signaling for Kras oncogene-driven pancreatic cell plasticity and cancer. Cancer Cell 23: 406-420.
    • (2013) Cancer Cell , vol.23 , pp. 406-420
    • Eser, S.1    Reiff, N.2    Messer, M.3    Seidler, B.4    Gottschalk, K.5    Dobler, M.6
  • 14
    • 0027250183 scopus 로고
    • Structural characterisation of native and recombinant forms of the neurotrophic cytokine MK
    • Fabri L, Maruta H, Muramatsu H, Muramatsu T, Simpson RJ, Burgess AW, et al. (1993). Structural characterisation of native and recombinant forms of the neurotrophic cytokine MK. J Chromatogr 646: 213-225.
    • (1993) J Chromatogr , vol.646 , pp. 213-225
    • Fabri, L.1    Maruta, H.2    Muramatsu, H.3    Muramatsu, T.4    Simpson, R.J.5    Burgess, A.W.6
  • 15
    • 84878017569 scopus 로고    scopus 로고
    • Association between hepatitis B or hepatitis C virus infection and risk of pancreatic adenocarcinoma development: A systematic review and meta-Analysis
    • Fiorino S, Chili E, Bacchi-Reggiani L, Masetti M, Deleonardi G, Grondona AG, et al. (2013). Association between hepatitis B or hepatitis C virus infection and risk of pancreatic adenocarcinoma development: a systematic review and meta-Analysis. Pancreatology 13: 147-160.
    • (2013) Pancreatology , vol.13 , pp. 147-160
    • Fiorino, S.1    Chili, E.2    Bacchi-Reggiani, L.3    Masetti, M.4    Deleonardi, G.5    Grondona, A.G.6
  • 16
    • 79960385475 scopus 로고    scopus 로고
    • Notch signaling activated by replication stress-induced expression of midkine drives epithelial-mesenchymal transition and chemoresistance in pancreatic cancer
    • Güngör C, Zander H, Effenberger KE, Vashist YK, Kalinina T, Izbicki JR, et al. (2011). Notch signaling activated by replication stress-induced expression of midkine drives epithelial-mesenchymal transition and chemoresistance in pancreatic cancer. Cancer Res 71: 5009-5019.
    • (2011) Cancer Res , vol.71 , pp. 5009-5019
    • Güngör, C.1    Zander, H.2    Effenberger, K.E.3    Vashist, Y.K.4    Kalinina, T.5    Izbicki, J.R.6
  • 17
    • 84893122015 scopus 로고    scopus 로고
    • Current developments, problems and solutions in the non-surgical treatment of pancreatic cancer
    • Guo XZ, Cui ZM, Liu X, (2013). Current developments, problems and solutions in the non-surgical treatment of pancreatic cancer. World J Gastrointest Oncol 5: 20-28.
    • (2013) World J Gastrointest Oncol , vol.5 , pp. 20-28
    • Guo, X.Z.1    Cui, Z.M.2    Liu, X.3
  • 19
    • 0030609980 scopus 로고    scopus 로고
    • Increased expression of alpha6-integrin receptors and of mRNA encoding the putative 37 kDa laminin receptor precursor in pancreatic carcinoma
    • Halatsch ME, Hirsch-Ernst KI, Kahl GF, Weinel RJ, (1997). Increased expression of alpha6-integrin receptors and of mRNA encoding the putative 37 kDa laminin receptor precursor in pancreatic carcinoma. Cancer Lett 118: 7-11.
    • (1997) Cancer Lett , vol.118 , pp. 7-11
    • Halatsch, M.E.1    Hirsch-Ernst, K.I.2    Kahl, G.F.3    Weinel, R.J.4
  • 20
    • 34948888231 scopus 로고    scopus 로고
    • Increased survival using platinum analog combined with gemcitabine as compared to single-Agent gemcitabine in advanced pancreatic cancer: Pooled analysis of two randomized trials, the GERCOR/GISCAD intergroup study and a German multicenter study
    • Heinemann V, Labianca R, Hinke A, Louvet C, (2007). Increased survival using platinum analog combined with gemcitabine as compared to single-Agent gemcitabine in advanced pancreatic cancer: pooled analysis of two randomized trials, the GERCOR/GISCAD intergroup study and a German multicenter study. Ann Oncol 18: 1652-1659.
    • (2007) Ann Oncol , vol.18 , pp. 1652-1659
    • Heinemann, V.1    Labianca, R.2    Hinke, A.3    Louvet, C.4
  • 22
    • 0025325071 scopus 로고
    • Evaluation of the antitumor activity of gemcitabine (2′,2′- difluoro-2′-deoxycytidine)
    • Hertel LW, Boder GB, Kroin JS, Rinzel SM, Poore GA, Todd GC, et al. (1990). Evaluation of the antitumor activity of gemcitabine (2′,2′- difluoro-2′-deoxycytidine). Cancer Res 50: 4417-4422.
    • (1990) Cancer Res , vol.50 , pp. 4417-4422
    • Hertel, L.W.1    Boder, G.B.2    Kroin, J.S.3    Rinzel, S.M.4    Poore, G.A.5    Todd, G.C.6
  • 23
    • 19344362405 scopus 로고    scopus 로고
    • Trp53R172H and KrasG12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice
    • Hingorani SR, Wang L, Multani AS, Combs C, Deramaudt TB, Hruban RH, et al. (2005). Trp53R172H and KrasG12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice. Cancer Cell 7: 469-483.
    • (2005) Cancer Cell , vol.7 , pp. 469-483
    • Hingorani, S.R.1    Wang, L.2    Multani, A.S.3    Combs, C.4    Deramaudt, T.B.5    Hruban, R.H.6
  • 24
    • 45849139695 scopus 로고    scopus 로고
    • Midkine induces epithelial-mesenchymal transition through Notch2/Jak2-Stat3 signaling in human keratinocytes
    • Huang Y, Hoque MO, Wu F, Trink B, Sidransky D, Ratovitski EA, (2008a). Midkine induces epithelial-mesenchymal transition through Notch2/Jak2-Stat3 signaling in human keratinocytes. Cell Cycle 7: 1613-1622.
    • (2008) Cell Cycle , vol.7 , pp. 1613-1622
    • Huang, Y.1    Hoque, M.O.2    Wu, F.3    Trink, B.4    Sidransky, D.5    Ratovitski, E.A.6
  • 25
    • 55549128887 scopus 로고    scopus 로고
    • Midkine promotes tetraspanin-integrin interaction and induces FAK-Stat1alpha pathway contributing to migration/invasiveness of human head and neck squamous cell carcinoma cells
    • Huang Y, Sook-Kim M, Ratovitski E, (2008b). Midkine promotes tetraspanin-integrin interaction and induces FAK-Stat1alpha pathway contributing to migration/invasiveness of human head and neck squamous cell carcinoma cells. Biochem Biophys Res Commun 377: 474-478.
    • (2008) Biochem Biophys Res Commun , vol.377 , pp. 474-478
    • Huang, Y.1    Sook-Kim, M.2    Ratovitski, E.3
  • 27
    • 84872389824 scopus 로고    scopus 로고
    • Protein-protein interaction and SNP analysis in intraductal papillary mucinous neoplasm
    • Jiang P, Zang W, Wang L, Xu Y, Liu Y, Deng SX, (2013). Protein-protein interaction and SNP analysis in intraductal papillary mucinous neoplasm. Gene 513: 219-224.
    • (2013) Gene , vol.513 , pp. 219-224
    • Jiang, P.1    Zang, W.2    Wang, L.3    Xu, Y.4    Liu, Y.5    Deng, S.X.6
  • 28
    • 52149123619 scopus 로고    scopus 로고
    • Core signaling pathways in human pancreatic cancers revealed by global genomic analyses
    • Jones S, Zhang X, Parsons DW, Lin JC, Leary RJ, Angenendt P, et al. (2008). Core signaling pathways in human pancreatic cancers revealed by global genomic analyses. Science 321: 1801-1806.
    • (2008) Science , vol.321 , pp. 1801-1806
    • Jones, S.1    Zhang, X.2    Parsons, D.W.3    Lin, J.C.4    Leary, R.J.5    Angenendt, P.6
  • 29
    • 0025304674 scopus 로고
    • A retinoic acid responsive gene MK found in the teratocarcinoma system is expressed in spatially and temporally controlled manner during mouse embryogenesis
    • Kadomatsu K, Huang RP, Suganuma T, Murata F, Muramatsu T, (1990). A retinoic acid responsive gene MK found in the teratocarcinoma system is expressed in spatially and temporally controlled manner during mouse embryogenesis. J Cell Biol 110: 607-616.
    • (1990) J Cell Biol , vol.110 , pp. 607-616
    • Kadomatsu, K.1    Huang, R.P.2    Suganuma, T.3    Murata, F.4    Muramatsu, T.5
  • 31
    • 84878566210 scopus 로고    scopus 로고
    • The heparin-binding growth factor midkine: The biological activities and candidate receptors
    • Kadomatsu K, Kishida S, Tsubota S, (2013). The heparin-binding growth factor midkine: the biological activities and candidate receptors. J Biochem 153: 511-521.
    • (2013) J Biochem , vol.153 , pp. 511-521
    • Kadomatsu, K.1    Kishida, S.2    Tsubota, S.3
  • 35
    • 34250734020 scopus 로고    scopus 로고
    • Acinar cell carcinoma of the pancreas: Clinical analysis of 115 patients from Pancreatic Cancer Registry of Japan Pancreas Society
    • Kitagami H, Kondo S, Hirano S, Kawakami H, Egawa S, Tanaka M, (2007). Acinar cell carcinoma of the pancreas: clinical analysis of 115 patients from Pancreatic Cancer Registry of Japan Pancreas Society. Pancreas 35: 42-46.
    • (2007) Pancreas , vol.35 , pp. 42-46
    • Kitagami, H.1    Kondo, S.2    Hirano, S.3    Kawakami, H.4    Egawa, S.5    Tanaka, M.6
  • 36
    • 84871715774 scopus 로고    scopus 로고
    • Identifying people at a high risk of developing pancreatic cancer
    • Klein AP, (2013). Identifying people at a high risk of developing pancreatic cancer. Nat Rev Cancer 13: 66-74.
    • (2013) Nat Rev Cancer , vol.13 , pp. 66-74
    • Klein, A.P.1
  • 37
    • 34248385189 scopus 로고    scopus 로고
    • Nonductal neoplasms of the pancreas
    • Klimstra DS, (2007). Nonductal neoplasms of the pancreas. Mod Pathol 20: S94-S112.
    • (2007) Mod Pathol , vol.20
    • Klimstra, D.S.1
  • 38
  • 39
    • 0029548635 scopus 로고
    • Pleiotrophin and midkine in normal development and tumor biology
    • Kurtz A, Schulte AM, Wellstein A, (1995). Pleiotrophin and midkine in normal development and tumor biology. Crit Rev Oncog 6: 151-177.
    • (1995) Crit Rev Oncog , vol.6 , pp. 151-177
    • Kurtz, A.1    Schulte, A.M.2    Wellstein, A.3
  • 40
    • 84876214630 scopus 로고    scopus 로고
    • 50 years of progress in pathophysiology, diagnosis and treatment of chronic pancreatitis
    • Lerch MM, Mayerle J, (2013). 50 years of progress in pathophysiology, diagnosis and treatment of chronic pancreatitis. Z Gastroenterol 51: 358-362.
    • (2013) Z Gastroenterol , vol.51 , pp. 358-362
    • Lerch, M.M.1    Mayerle, J.2
  • 41
    • 79953756112 scopus 로고    scopus 로고
    • Stat3/Socs3 activation by IL-6 transsignaling promotes progression of pancreatic intraepithelial neoplasia and development of pancreatic cancer
    • Lesina M, Kurkowski MU, Ludes K, Rose-John S, Treiber M, Klöppel G, et al. (2011). Stat3/Socs3 activation by IL-6 transsignaling promotes progression of pancreatic intraepithelial neoplasia and development of pancreatic cancer. Cancer Cell 19: 456-469.
    • (2011) Cancer Cell , vol.19 , pp. 456-469
    • Lesina, M.1    Kurkowski, M.U.2    Ludes, K.3    Rose-John, S.4    Treiber, M.5    Klöppel, G.6
  • 42
    • 84855946746 scopus 로고    scopus 로고
    • KrasG12D-induced IKK2/β/NF-κB activation by IL-1α and p62 feedforward loops is required for development of pancreatic ductal adenocarcinoma
    • Ling J, Kang Y, Zhao R, Xia Q, Lee DF, Chang Z, et al. (2012). KrasG12D-induced IKK2/β/NF-κB activation by IL-1α and p62 feedforward loops is required for development of pancreatic ductal adenocarcinoma. Cancer Cell 21: 105-120.
    • (2012) Cancer Cell , vol.21 , pp. 105-120
    • Ling, J.1    Kang, Y.2    Zhao, R.3    Xia, Q.4    Lee, D.F.5    Chang, Z.6
  • 44
    • 0028296179 scopus 로고
    • Association of transcription factor APRF and protein kinase Jak1 with the interleukin-6 signal transducer gp130
    • Lütticken C, Wegenka UM, Yuan J, Buschmann J, Schindler C, Ziemiecki A, et al. (1994). Association of transcription factor APRF and protein kinase Jak1 with the interleukin-6 signal transducer gp130. Science 263: 89-92.
    • (1994) Science , vol.263 , pp. 89-92
    • Lütticken, C.1    Wegenka, U.M.2    Yuan, J.3    Buschmann, J.4    Schindler, C.5    Ziemiecki, A.6
  • 45
    • 0037044716 scopus 로고    scopus 로고
    • Evidence of functional modulation of the MEKK/JNK/cJun signaling cascade by the low density lipoprotein receptor-related protein (LRP)
    • Lutz C, Nimpf J, Jenny M, Boecklinger K, Enzinger C, Utermann G, et al. (2002). Evidence of functional modulation of the MEKK/JNK/cJun signaling cascade by the low density lipoprotein receptor-related protein (LRP). J Biol Chem 277: 43143-43151.
    • (2002) J Biol Chem , vol.277 , pp. 43143-43151
    • Lutz, C.1    Nimpf, J.2    Jenny, M.3    Boecklinger, K.4    Enzinger, C.5    Utermann, G.6
  • 46
    • 34547596646 scopus 로고    scopus 로고
    • Clinical significance of midkine expression in pancreatic head carcinoma
    • Maeda S, Shinchi H, Kurahara H, Mataki Y, Noma H, Maemura K, et al. (2007). Clinical significance of midkine expression in pancreatic head carcinoma. Br J Cancer 97: 405-411.
    • (2007) Br J Cancer , vol.97 , pp. 405-411
    • Maeda, S.1    Shinchi, H.2    Kurahara, H.3    Mataki, Y.4    Noma, H.5    Maemura, K.6
  • 47
    • 84875159380 scopus 로고    scopus 로고
    • Pancreatic cancer genomics: Insights and opportunities for clinical translation
    • Makohon-Moore A, Brosnan JA, Iacobuzio-Donahue CA, (2013). Pancreatic cancer genomics: insights and opportunities for clinical translation. Genome Med 5: 26.
    • (2013) Genome Med , vol.5 , pp. 26
    • Makohon-Moore, A.1    Brosnan, J.A.2    Iacobuzio-Donahue, C.A.3
  • 48
    • 77954520482 scopus 로고    scopus 로고
    • Midkine inhibitors: Application of a simple assay procedure to screening of inhibitory compounds
    • Matsui T, Ichihara-Tanaka K, Lan C, Muramatsu H, Kondou T, Hirose C, et al. (2010). Midkine inhibitors: application of a simple assay procedure to screening of inhibitory compounds. Int Arch Med 21: 12.
    • (2010) Int Arch Med , vol.21 , pp. 12
    • Matsui, T.1    Ichihara-Tanaka, K.2    Lan, C.3    Muramatsu, H.4    Kondou, T.5    Hirose, C.6
  • 50
    • 10744223624 scopus 로고    scopus 로고
    • Notch mediates TGF alpha-induced changes in epithelial differentiation during pancreatic tumorigenesis
    • Miyamoto Y, Maitra A, Ghosh B, Zechner U, Argani P, Iacobuzio-Donahue CA, et al. (2003). Notch mediates TGF alpha-induced changes in epithelial differentiation during pancreatic tumorigenesis. Cancer Cell 3: 565-576.
    • (2003) Cancer Cell , vol.3 , pp. 565-576
    • Miyamoto, Y.1    Maitra, A.2    Ghosh, B.3    Zechner, U.4    Argani, P.5    Iacobuzio-Donahue, C.A.6
  • 53
    • 65249147725 scopus 로고    scopus 로고
    • Ligand-dependent Notch signaling is involved in tumor initiation and tumor maintenance in pancreatic cancer
    • Mullendore ME, Koorstra JB, Li YM, Offerhaus GJ, Fan X, Henderson CM, et al. (2009). Ligand-dependent Notch signaling is involved in tumor initiation and tumor maintenance in pancreatic cancer. Clin Cancer Res 15: 2291-2301.
    • (2009) Clin Cancer Res , vol.15 , pp. 2291-2301
    • Mullendore, M.E.1    Koorstra, J.B.2    Li, Y.M.3    Offerhaus, G.J.4    Fan, X.5    Henderson, C.M.6
  • 55
    • 9444262481 scopus 로고    scopus 로고
    • Alpha4beta1- and alpha6beta1-integrins are functional receptors for midkine, a heparin-binding growth factor
    • Muramatsu H, Zou P, Suzuki H, Oda Y, Chen GY, Sakaguchi N, et al. (2004). alpha4beta1- and alpha6beta1-integrins are functional receptors for midkine, a heparin-binding growth factor. J Cell Sci 117: 5405-5415.
    • (2004) J Cell Sci , vol.117 , pp. 5405-5415
    • Muramatsu, H.1    Zou, P.2    Suzuki, H.3    Oda, Y.4    Chen, G.Y.5    Sakaguchi, N.6
  • 56
    • 0036739307 scopus 로고    scopus 로고
    • Midkine and pleiotrophin: Two related proteins involved in development, survival, inflammation and tumorigenesis
    • Muramatsu T, (2002). Midkine and pleiotrophin: two related proteins involved in development, survival, inflammation and tumorigenesis. J. Biochem. 132: 359-371.
    • (2002) J. Biochem. , vol.132 , pp. 359-371
    • Muramatsu, T.1
  • 57
    • 77954503361 scopus 로고    scopus 로고
    • Midkine, a heparin-binding cytokine with multiple roles in development, repair and diseases
    • Muramatsu T, (2010). Midkine, a heparin-binding cytokine with multiple roles in development, repair and diseases. Proc Jpn Acad Ser B Phys Biol Sci 86: 410-425.
    • (2010) Proc Jpn Acad ser B Phys Biol Sci , vol.86 , pp. 410-425
    • Muramatsu, T.1
  • 58
    • 79953325739 scopus 로고    scopus 로고
    • Midkine: A promising molecule for drug development to treat diseases of the central nervous system
    • Muramatsu T, (2011). Midkine: a promising molecule for drug development to treat diseases of the central nervous system. Curr Pharm Des 17: 410-423.
    • (2011) Curr Pharm des , vol.17 , pp. 410-423
    • Muramatsu, T.1
  • 59
    • 13444260998 scopus 로고    scopus 로고
    • Truncated midkine induces transformation of cultured cells and short latency of tumorigenesis in nude mice
    • Nobata S, Shinozawa T, Sakanishi A, (2005). Truncated midkine induces transformation of cultured cells and short latency of tumorigenesis in nude mice. Cancer Lett 219: 83-89.
    • (2005) Cancer Lett , vol.219 , pp. 83-89
    • Nobata, S.1    Shinozawa, T.2    Sakanishi, A.3
  • 60
    • 34547445606 scopus 로고    scopus 로고
    • Cytotoxic therapy for advanced pancreatic adenocarcinoma
    • O'Reilly EM, Abou-Alfa GK, (2007). Cytotoxic therapy for advanced pancreatic adenocarcinoma. Semin Oncol 34: 347-353.
    • (2007) Semin Oncol , vol.34 , pp. 347-353
    • O'Reilly, E.M.1    Abou-Alfa, G.K.2
  • 62
    • 79957651010 scopus 로고    scopus 로고
    • Exocrine pancreatic neoplasms of nonductal origin: Acinar cell carcinoma, pancreatoblastoma, and solid-pseudopapillary neoplasm
    • Ohike N, Morohoshi T, (2011). Exocrine pancreatic neoplasms of nonductal origin: acinar cell carcinoma, pancreatoblastoma, and solid-pseudopapillary neoplasm. Surg Pathol Clin 4: 579-588.
    • (2011) Surg Pathol Clin , vol.4 , pp. 579-588
    • Ohike, N.1    Morohoshi, T.2
  • 64
    • 77949647348 scopus 로고    scopus 로고
    • Targeted therapies for pancreatic cancer
    • Philip PA, (2008). Targeted therapies for pancreatic cancer. Gastrointest Cancer Res. 2 (4 Suppl. 2): S16-S19.
    • (2008) Gastrointest Cancer Res. , vol.2 , Issue.4 SUPPL. 2
    • Philip, P.A.1
  • 65
    • 0032488833 scopus 로고    scopus 로고
    • Midkine induces tumor cell proliferation and binds to a high affinity signalling receptor associated with JAK tyrosine kinases
    • Ratovitski EA, Kotzbauer PT, Milbrandt J, Lowenstein CJ, Burrow CR, (1998). Midkine induces tumor cell proliferation and binds to a high affinity signalling receptor associated with JAK tyrosine kinases. J Biol Chem 273: 3654-3660.
    • (1998) J Biol Chem , vol.273 , pp. 3654-3660
    • Ratovitski, E.A.1    Kotzbauer, P.T.2    Milbrandt, J.3    Lowenstein, C.J.4    Burrow, C.R.5
  • 66
    • 0035451087 scopus 로고    scopus 로고
    • The affinity of integrin alpha(4)beta(1) governs lymphocyte migration
    • Rose DM, Grabovsky V, Alon R, Ginsberg MH, (2001). The affinity of integrin alpha(4)beta(1) governs lymphocyte migration. J Immunol 167: 2824-2830.
    • (2001) J Immunol , vol.167 , pp. 2824-2830
    • Rose, D.M.1    Grabovsky, V.2    Alon, R.3    Ginsberg, M.H.4
  • 67
    • 34648830232 scopus 로고    scopus 로고
    • Controversies in the adjuvant treatment of pancreatic adenocarcinoma
    • Saif MW, (2007). Controversies in the adjuvant treatment of pancreatic adenocarcinoma. JOP 8: 545-552.
    • (2007) JOP , vol.8 , pp. 545-552
    • Saif, M.W.1
  • 68
    • 79953128574 scopus 로고    scopus 로고
    • Premature ligand- receptor interaction during biosynthesis limits the production of growth factor midkine and its receptor LDL receptor-related protein 1
    • Sakamoto K, Bu G, Chen S, Takei Y, Hibi K, Kodera Y, et al. (2011). Premature ligand- receptor interaction during biosynthesis limits the production of growth factor midkine and its receptor LDL receptor-related protein 1. J Biol Chem 286: 8405-8413.
    • (2011) J Biol Chem , vol.286 , pp. 8405-8413
    • Sakamoto, K.1    Bu, G.2    Chen, S.3    Takei, Y.4    Hibi, K.5    Kodera, Y.6
  • 69
    • 16944367477 scopus 로고    scopus 로고
    • Abrogation of the Rb/p16 tumor-suppressive pathway in virtually all pancreatic carcinomas
    • Schutte M, Hruban RH, Geradts J, Maynard R, Hilgers W, Rabindran SK, et al. (1997). Abrogation of the Rb/p16 tumor-suppressive pathway in virtually all pancreatic carcinomas. Cancer Res 57: 3126-3130.
    • (1997) Cancer Res , vol.57 , pp. 3126-3130
    • Schutte, M.1    Hruban, R.H.2    Geradts, J.3    Maynard, R.4    Hilgers, W.5    Rabindran, S.K.6
  • 70
    • 0037182578 scopus 로고    scopus 로고
    • Dual functions of [alpha]4[beta]1 integrin in epicardial development: Initial migration and long-term attachment
    • Sengbusch JK, He W, Pinco KA, Yang JT, (2002). Dual functions of [alpha]4[beta]1 integrin in epicardial development: initial migration and long-term attachment. J Cell Biol 157: 873-882.
    • (2002) J Cell Biol , vol.157 , pp. 873-882
    • Sengbusch, J.K.1    He, W.2    Pinco, K.A.3    Yang, J.T.4
  • 72
    • 0042563122 scopus 로고    scopus 로고
    • Preoperative serum midkine concentration is a prognostic marker for esophageal squamous cell carcinoma
    • Shimada H, Nabeya Y, Tagawa M, Okazumi S, Matsubara H, Kadomatsu K, et al. (2003). Preoperative serum midkine concentration is a prognostic marker for esophageal squamous cell carcinoma. Cancer Sci 94: 628-632.
    • (2003) Cancer Sci , vol.94 , pp. 628-632
    • Shimada, H.1    Nabeya, Y.2    Tagawa, M.3    Okazumi, S.4    Matsubara, H.5    Kadomatsu, K.6
  • 74
    • 84875798461 scopus 로고    scopus 로고
    • LCN2 and TIMP1 as potential serum markers for the early detection of familial pancreatic cancer
    • Slater EP, Fendrich V, Strauch K, Rospleszcz S, Ramaswamy A, Mätthai E, et al. (2013). LCN2 and TIMP1 as potential serum markers for the early detection of familial pancreatic cancer. Transl Oncol 6: 99-103.
    • (2013) Transl Oncol , vol.6 , pp. 99-103
    • Slater, E.P.1    Fendrich, V.2    Strauch, K.3    Rospleszcz, S.4    Ramaswamy, A.5    Mätthai, E.6
  • 75
    • 84872040888 scopus 로고    scopus 로고
    • Targeting the tumor microenvironment for cancer therapy
    • Sounni NE, Noel A, (2013). Targeting the tumor microenvironment for cancer therapy. Clin Chem 59: 85-93.
    • (2013) Clin Chem , vol.59 , pp. 85-93
    • Sounni, N.E.1    Noel, A.2
  • 76
    • 84880054952 scopus 로고    scopus 로고
    • Myeloid cell receptor LRP1/CD91 regulates monocyte recruitment and angiogenesis in tumors
    • Staudt ND, Jo M, Hu J, Bristow JM, Pizzo DP, Gaultier A, et al. (2013). Myeloid cell receptor LRP1/CD91 regulates monocyte recruitment and angiogenesis in tumors. Cancer Res 73: 3902-3912.
    • (2013) Cancer Res , vol.73 , pp. 3902-3912
    • Staudt, N.D.1    Jo, M.2    Hu, J.3    Bristow, J.M.4    Pizzo, D.P.5    Gaultier, A.6
  • 77
    • 84875210349 scopus 로고    scopus 로고
    • Re-resection for isolated local recurrence of pancreatic cancer is feasible, safe, and associated with encouraging survival
    • Strobel O, Hartwig W, Hackert T, Hinz U, Berens V, Grenacher L, et al. (2013). Re-resection for isolated local recurrence of pancreatic cancer is feasible, safe, and associated with encouraging survival. Ann Surg Oncol 20: 964-972.
    • (2013) Ann Surg Oncol , vol.20 , pp. 964-972
    • Strobel, O.1    Hartwig, W.2    Hackert, T.3    Hinz, U.4    Berens, V.5    Grenacher, L.6
  • 78
    • 0035577793 scopus 로고    scopus 로고
    • Antisense oligodeoxynucleotide targeted to Midkine, a heparin-binding growth factor, suppresses tumorigenicity of mouse rectal carcinoma cells
    • Takei Y, Kadomatsu K, Matsuo S, Itoh H, Nakazawa K, Kubota S, et al. (2001). Antisense oligodeoxynucleotide targeted to Midkine, a heparin-binding growth factor, suppresses tumorigenicity of mouse rectal carcinoma cells. Cancer Res 61: 8486-8491.
    • (2001) Cancer Res , vol.61 , pp. 8486-8491
    • Takei, Y.1    Kadomatsu, K.2    Matsuo, S.3    Itoh, H.4    Nakazawa, K.5    Kubota, S.6
  • 79
    • 33747177852 scopus 로고    scopus 로고
    • Combinational antitumor effect of siRNA against midkine and paclitaxel on growth of human prostate cancer xenografts
    • Takei Y, Kadomatsu K, Goto T, Muramatsu T, (2006). Combinational antitumor effect of siRNA against midkine and paclitaxel on growth of human prostate cancer xenografts. Cancer 107: 864-873.
    • (2006) Cancer , vol.107 , pp. 864-873
    • Takei, Y.1    Kadomatsu, K.2    Goto, T.3    Muramatsu, T.4
  • 80
    • 36549069246 scopus 로고    scopus 로고
    • Midkine promoter-based conditionally replicative adenovirus for targeting midkine-expressing human bladder cancer model
    • Terao S, Shirakawa T, Kubo S, Bishunu A, Lee SJ, Goda K, et al. (2007). Midkine promoter-based conditionally replicative adenovirus for targeting midkine-expressing human bladder cancer model. Urology 70: 1009-1013.
    • (2007) Urology , vol.70 , pp. 1009-1013
    • Terao, S.1    Shirakawa, T.2    Kubo, S.3    Bishunu, A.4    Lee, S.J.5    Goda, K.6
  • 81
    • 0025316866 scopus 로고
    • A retinoic acid-responsive gene, MK, found in the teratocarcinoma system. Heterogeneity of the transcript and the nature of the translation product
    • Tomomura M, Kadomatsu K, Matsubara S, Muramatsu T, (1990). A retinoic acid-responsive gene, MK, found in the teratocarcinoma system. Heterogeneity of the transcript and the nature of the translation product. J Biol Chem 265: 10765-10770.
    • (1990) J Biol Chem , vol.265 , pp. 10765-10770
    • Tomomura, M.1    Kadomatsu, K.2    Matsubara, S.3    Muramatsu, T.4
  • 82
    • 0026536043 scopus 로고
    • Genomic structure of human midkine (MK), a retinoic acid-responsive growth/differentiation factor
    • Uehara K, Matsubara S, Kadomatsu K, Tsutsui J, Muramatsu T, (1992). Genomic structure of human midkine (MK), a retinoic acid-responsive growth/differentiation factor. J Biochem 111: 563-567.
    • (1992) J Biochem , vol.111 , pp. 563-567
    • Uehara, K.1    Matsubara, S.2    Kadomatsu, K.3    Tsutsui, J.4    Muramatsu, T.5
  • 84
  • 85
    • 47549093707 scopus 로고    scopus 로고
    • 672 patients with acinar cell carcinoma of the pancreas: A population based comparison to pancreatic adenocarcinoma
    • Wisnoski NC, Townsend CM Jr, Nealon WH, Freeman JL, Riall TS, (2008). 672 patients with acinar cell carcinoma of the pancreas: a population based comparison to pancreatic adenocarcinoma. Surgery 144: 141-148.
    • (2008) Surgery , vol.144 , pp. 141-148
    • Wisnoski, N.C.1    Townsend, Jr.C.M.2    Nealon, W.H.3    Freeman, J.L.4    Riall, T.S.5
  • 86
    • 79961141540 scopus 로고    scopus 로고
    • Targeted therapies for gastric cancer: Current status
    • Yoong J, Michael M, Leong T, (2011). Targeted therapies for gastric cancer: current status. Drugs 71: 1367-1384.
    • (2011) Drugs , vol.71 , pp. 1367-1384
    • Yoong, J.1    Michael, M.2    Leong, T.3
  • 87
    • 0032951527 scopus 로고    scopus 로고
    • Pleiotrophin and midkine, a family of mitogenic and angiogenic heparin-binding growth and differentiation factors
    • Zhang N, Deuel TF, (1999). Pleiotrophin and midkine, a family of mitogenic and angiogenic heparin-binding growth and differentiation factors. Curr Opin Hematol 6: 44-50.
    • (1999) Curr Opin Hematol , vol.6 , pp. 44-50
    • Zhang, N.1    Deuel, T.F.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.