Induction of diabetes in the RIP-B7.1 mouse model is critically dependent on TLR3 and MyD88 pathways and is associated with alterations in the intestinal microbiome

Diabetes

Volumn 63, Issue 2, 2014, Pages 619-631

  Alkanani, Aimon K ^a   Hara, Naoko ^a   Lien, Egil ^b   Ir, Diana ^c   Kotter, Cassandra V ^c   Robertson, Charles E ^d,e   Wagner, Brandie D ^e,f   Frank, Daniel N ^c,e   Zipris, Danny ^a  

^a UNIVERSITY OF COLORADO DENVER   (United States)

^b UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF COLORADO   (United States)

^e UNIVERSITY OF COLORADO   (United States)

^f Global Health and Health Disparities   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; COTRIMOXAZOLE; DNA; MYELOID DIFFERENTIATION FACTOR 88; POLYINOSINIC POLYCYTIDYLIC ACID; RETINOIC ACID INDUCIBLE PROTEIN I; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 9;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOINFORMATICS; CONTROLLED STUDY; DIABETES MELLITUS; DISEASE COURSE; DNA SEQUENCE; HIGH THROUGHPUT SEQUENCING; INTESTINE FLORA; MICROBIAL COMMUNITY; MICROBIOME; MOUSE; NONHUMAN; PANCREAS ISLET; PHYLUM; PRINCIPAL COMPONENT ANALYSIS; PRIORITY JOURNAL; TRANSGENIC MOUSE; WILD TYPE;

ANIMALS; BACTERIA; DIABETES MELLITUS; GENE EXPRESSION REGULATION; INTESTINES; MICE; MICE, INBRED C57BL; MICE, INBRED STRAINS; MICE, KNOCKOUT; MYELOID DIFFERENTIATION FACTOR 88; POLY I-C; TOLL-LIKE RECEPTOR 3; TOLL-LIKE RECEPTOR 9;

EID: 84893059739     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db13-1007     Document Type: Article

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