A mitochondrial location for haemoglobins-Dynamic distribution in ageing and Parkinson's disease

Mitochondrion

Volumn 14, Issue 1, 2014, Pages 64-72

  Shephard, Freya ^a   Greville Heygate, Oliver ^a   Marsh, Oliver ^a   Anderson, Susan ^b   Chakrabarti, Lisa ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^b UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

Ageing; Haemoglobin; Mitochondria; Neurodegeneration; Parkinson's Disease

Indexed keywords

HEMOGLOBIN BETA CHAIN; PROTEIN HBA; PROTEIN HBB; UNCLASSIFIED DRUG;

AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN MITOCHONDRION; CELL FRACTIONATION; CELL LOSS; CYTOPLASM; IMMUNOHISTOCHEMISTRY; MITOCHONDRIAL MEMBRANE; MOLECULAR DYNAMICS; MOUSE; MUSCLE CELL; NERVE CELL DEGENERATION; NERVE DEGENERATION; NONHUMAN; PARKINSON DISEASE; PRIORITY JOURNAL; PROTEIN CONTENT; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PURKINJE CELL; SUBSTANTIA NIGRA; TISSUE SPECIFICITY; WESTERN BLOTTING;

MAMMALIA; VERTEBRATA;

AGEING; HAEMOGLOBIN; MITOCHONDRIA; NEURODEGENERATION; PARKINSON'S DISEASE;

AGING; ANIMALS; BRAIN; CYTOPLASM; HEMOGLOBIN A; HEMOGLOBINS; HUMANS; MICE; MITOCHONDRIA; MUSCLES; PARKINSON DISEASE;

EID: 84892990688     PISSN: 15677249     EISSN: 18728278     Source Type: Journal    
DOI: 10.1016/j.mito.2013.12.001     Document Type: Article

References (34)

1. Alexa A., Rahnenführer J., Lengauer T. Improved scoring of functional groups from gene expression data by decorrelating GO graph structure. Bioinformatics 2006, 22:1600-1607. 10.1093/bioinformatics/btl140.
2. Barbaric I., Miller G., Dear T.N. Appearances can be deceiving: phenotypes of knockout mice. Brief. Funct. Genomic Proteomic 2007, 6:91-103. 10.1093/bfgp/elm008.
3. 1 receptors regulate neuronal energy metabolism. Nat. Neurosci. 2012, 15:558-564. 10.1038/nn.3053.
4. Chakrabarti L., Neal J.T., Miles M., Martinez R.A., Smith A.C., et al. The Purkinje cell degeneration 5J mutation is a single amino acid insertion that destabilizes Nna1 protein. Mamm. Genome 2006, 17:103-110. 10.1007/s00335-005-0096-x.
5. Chakrabarti L., Eng J., Martinez R.A., Jackson S., Huang J., et al. The zinc-binding domain of Nna1 is required to prevent retinal photoreceptor loss and cerebellar ataxia in Purkinje cell degeneration (pcd) mice. Vision Res. 2008, 48:1999-2005. 10.1016/j.visres.2008.05.026.
6. Chakrabarti L., Eng J., Ivanov N., Garden G.A., La Spada A.R. Autophagy activation and enhanced mitophagy characterize the Purkinje cells of pcd mice prior to neuronal death. Mol. Brain 2009, 2:24. 10.1186/1756-6606-2-24.
7. Chakrabarti L., Zahra R., Jackson S.M., Kazemi-Esfarjani P., Sopher B.L., et al. Mitochondrial dysfunction in NnaD mutant flies and Purkinje cell degeneration mice reveals a role for Nna proteins in neuronal bioenergetics. Neuron 2010, 66:835-847. 10.1016/j.neuron.2010.05.024.
8. Chu C.T. Tickled PINK1: mitochondrial homeostasis and autophagy in recessive Parkinsonism. Biochim. Biophys. Acta 2010, 1802:20-28. 10.1016/j.bbadis.2009.06.012.
9. Chuang J.-Y., Lee C.-W., Shih Y.-H., Yang T., Yu L., et al. Interactions between amyloid-β and hemoglobin: implications for amyloid plaque formation in Alzheimer's disease. PLoS One 2012, 7:e33120. 10.1371/journal.pone.0033120.
10. Cookson M.R. Evolution of neurodegeneration. Curr. Biol. 2012, 22:R753-61. 10.1016/j.cub.2012.07.008.
11. Daulatzai M.A. Death by a thousand cuts in Alzheimer's disease: hypoxia-the prodrome. Neurotox. Res 2013, 10.1007/s12640-013-9379-2.
12. Ferrer I., Gómez A., Carmona M., Huesa G., Porta S., et al. Neuronal hemoglobin is reduced in Alzheimer's disease, argyrophilic grain disease, Parkinson's disease, and dementia with Lewy bodies. J. Alzheimers Dis. 2011, 23:537-550. (Available: http://iospress.metapress.com/content/4152218568037041/?genre=article&issn=1387-2877&volume=23&issue=3&spage=537. Accessed 22 January 2013).
13. Ferrer I., Martinez A., Blanco R., Dalfó E., Carmona M. Neuropathology of sporadic Parkinson disease before the appearance of parkinsonism: preclinical Parkinson disease. J. Neural Transm. 2011, 118:821-839. 10.1007/s00702-010-0482-8.
14. Fleming M.D., Hamza I. Mitochondrial heme: an exit strategy at last. Mammalian 2011, 10. 10.1172/JCI66607.
15. Gakh O., Park S., Liu G., Macomber L., Imlay J.A., et al. Mitochondrial iron detoxification is a primary function of frataxin that limits oxidative damage and preserves cell longevity. Hum. Mol. Genet. 2006, 15:467-479. 10.1093/hmg/ddi461.
16. Gaskell H., Derry S., Andrew Moore R., McQuay H.J. Prevalence of anaemia in older persons: systematic review. BMC Geriatr. 2008, 8:1. 10.1186/1471-2318-8-1.
17. Gomes I., Grushko J.S., Golebiewska U., Hoogendoorn S., Gupta A., et al. Novel endogenous peptide agonists of cannabinoid receptors. FASEB J. 2009, 23:3020-3029. 10.1096/fj.09-132142.
18. He Y., Hua Y., Liu W., Hu H., Keep R.F., et al. Effects of cerebral ischemia on neuronal hemoglobin. J. Cereb. Blood Flow Metab. 2009, 29:596-605. 10.1038/jcbfm.2008.145.
19. Hu F., Liu F. Mitochondrial stress: a bridge between mitochondrial dysfunction and metabolic diseases?. Cell. Signal. 2011, 23:1528-1533. 10.1016/j.cellsig.2011.05.008.
20. Neuronal Hemoglobin is Reduced in Alzheimer's Disease, Argyrophilic Grain Disease, Parkinson's Disease, and Dementia with Lewy Bodies - Journal of Alzheimer's Disease - Volume 23, Number 3 / 2011 - IOS Press (n.d.). Available: Accessed 22 January 2013. http://iospress.metapress.com/content/4152218568037041/?genre=article&issn=1387-2877&volume=23&issue=3&spage=537.
21. Lechauve C., Augustin S., Cwerman-Thibault H., Bouaita A., Forster V., et al. Neuroglobin involvement in respiratory chain function and retinal ganglion cell integrity. Biochim. Biophys. Acta 2012, 1823:2261-2273. 10.1016/j.bbamcr.2012.09.009.
22. Moens L., Bolognesi M., di Prisco G., Verde C., Vinogradov S.N., et al. A model of globin evolution. Gene 2007, 398:132-142.
23. Perfeito R., Cunha-Oliveira T., Rego A.C. Revisiting oxidative stress and mitochondrial dysfunction in the pathogenesis of Parkinson disease-resemblance to the effect of amphetamine drugs of abuse. Free Radic. Biol. Med. 2012, 53:1791-1806. 10.1016/j.freeradbiomed.2012.08.569.
24. Peterson C.M., Johannsen D.L., Ravussin E. Skeletal muscle mitochondria and aging: a review. J. Aging Res. 2012, 2012:194821. 10.1155/2012/194821.
25. Rugarli E.I., Langer T. Mitochondrial quality control: a matter of life and death for neurons. EMBO J. 2012, 31:1336-1349. 10.1038/emboj.2012.38.
26. Santos D., Cardoso S.M. Mitochondrial dynamics and neuronal fate in Parkinson's disease. Mitochondrion 2012, 12:428-437. 10.1016/j.mito.2012.05.002.
27. Savica R., Grossardt B.R., Carlin J.M., Icen M., Bower J.H., et al. Anemia or low hemoglobin levels preceding Parkinson disease: a case-control study. Neurology 2009, 73:1381-1387. 10.1212/WNL.0b013e3181bd80c1.
28. Schelshorn D.W., Schneider A., Kuschinsky W., Weber D., Krüger C., et al. Expression of hemoglobin in rodent neurons. J. Cereb. Blood Flow Metab. 2009, 29:585-595. 10.1038/jcbfm.2008.152.
29. Sian-Hülsmann J., Mandel S., Youdim M.B.H., Riederer P. The relevance of iron in the pathogenesis of Parkinson's disease. J. Neurochem. 2011, 118:939-957. 10.1111/j.1471-4159.2010.07132.x.
30. Straub A.C., Lohman A.W., Billaud M., Johnstone S.R., Dwyer S.T., et al. Endothelial cell expression of haemoglobin α regulates nitric oxide signalling. Nature 2012, 491:473-477. 10.1038/nature11626.
31. Vinogradov S.N., Hoogewijs D., Bailly X., Arredondo-Peter R., Gough J., et al. A phylogenomic profile of globins. BMC Evol. Biol. 2006, 6:31. 10.1186/1471-2148-6-31.
32. Wallace D.C. Mitochondria and cancer. Nat. Rev. Cancer 2012, 12:685-698. 10.1038/nrc3365.
33. Yan M.H., Wang X., Zhu X. Mitochondrial defects and oxidative stress in Alzheimer's disease and Parkinson's disease. Free Radic. Biol. Med. Null 2012, 10.1016/j.freeradbiomed.2012.11.014.
34. Yu Z., Xu J., Liu N., Wang Y., Li X., et al. Mitochondrial distribution of neuroglobin and its response to oxygen-glucose deprivation in primary-cultured mouse cortical neurons. Neuroscience 2012, 218:235-242. 10.1016/j.neuroscience.2012.05.054.