The zinc-binding domain of Nna1 is required to prevent retinal photoreceptor loss and cerebellar ataxia in Purkinje cell degeneration (pcd) mice

Vision Research

Volumn 48, Issue 19, 2008, Pages 1999-2005

  Chakrabarti, Lisa ^a   Eng, Jeremiah ^a   Martinez, Refugio A ^a   Jackson, Stephen ^a   Huang, Jing ^a   Possin, Daniel E ^a   Sopher, Bryce L ^a   Spada, Albert R La ^a  

^a UNIVERSITY OF WASHINGTON MEDICAL CENTER   (United States)

Author keywords

Genetic rescue; Purkinje cell degeneration; Retinal photoreceptor degeneration; Zinc dependent carboxypeptidase

Indexed keywords

NNA1 PROTEIN; ZINC BINDING PROTEIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL DEGENERATION; CELL LOSS; CELL POPULATION; CELL SURVIVAL; CEREBELLAR ATAXIA; CONTROLLED STUDY; FEMALE; GENE MUTATION; MALE; MOUSE; NERVE CELL; NONHUMAN; PHENOTYPE; PHOTORECEPTOR; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PURKINJE CELL; TRANSGENE;

AMINO ACID SEQUENCE; ANIMALS; CEREBELLAR ATAXIA; GENOTYPE; GTP-BINDING PROTEINS; MICE; MICE, TRANSGENIC; MOLECULAR SEQUENCE DATA; POLYMERASE CHAIN REACTION; PURKINJE CELLS; RETINAL DEGENERATION; SERINE-TYPE D-ALA-D-ALA CARBOXYPEPTIDASE; ZINC;

EID: 48749085672     PISSN: 00426989     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.visres.2008.05.026     Document Type: Article

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