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Volumn 5, Issue 3, 2013, Pages 177-185

Biocompatibility and biotolerability assessment of microspheres using a whole blood model

Author keywords

Alginate; Biocompatibility; Biomaterial; Inflammation; Microbead; Microcapsule; Whole blood

Indexed keywords

CELL SURFACE RECEPTORS; CELL TRANSPLANTATION; IDENTICAL CONDITIONS; INFLAMMATION; INFLAMMATORY REACTION; MICROBEADS; MICROCAPSULES; WHOLE BLOOD;

EID: 84892988258     PISSN: 18764029     EISSN: 18764037     Source Type: Journal    
DOI: 10.2174/1876402911305030005     Document Type: Review
Times cited : (8)

References (117)
  • 2
    • 0037222059 scopus 로고    scopus 로고
    • Survival and maturation of microencapsulated porcine neonatal pancreatic cell clusters transplanted into immunocompetent diabetic mice
    • Omer, A.; Duvivier-Kali, V. F.; Trivedi, N.; Wilmot, K.; Bonner-Weir, S.; Weir, G. C. Survival and maturation of microencapsulated porcine neonatal pancreatic cell clusters transplanted into immunocompetent diabetic mice. Diabetes, 2003, 52(1), 69-75.
    • (2003) Diabetes , vol.52 , Issue.1 , pp. 69-75
    • Omer, A.1    Duvivier-Kali, V.F.2    Trivedi, N.3    Wilmot, K.4    Bonner-Weir, S.5    Weir, G.C.6
  • 3
    • 0029027755 scopus 로고
    • Xenotransplantation of porcine and bovine islets without immunosuppression using uncoated alginate microspheres
    • Lanza, R. P.; Kuhtreiber, W. M.; Ecker, D.; Staruk, J. E.; Chick, W. L. Xenotransplantation of porcine and bovine islets without immunosuppression using uncoated alginate microspheres. Transplantation, 1995, 59(10), 1377-1384.
    • (1995) Transplantation , vol.59 , Issue.10 , pp. 1377-1384
    • Lanza, R.P.1    Kuhtreiber, W.M.2    Ecker, D.3    Staruk, J.E.4    Chick, W.L.5
  • 4
    • 0035433196 scopus 로고    scopus 로고
    • Complete protection of islets against allorejection and autoimmunity by a simple barium-alginate membrane
    • Duvivier-Kali, V. F.; Omer, A.; Parent, R. J.; O'Neil, J. J.; Weir, G. C. Complete protection of islets against allorejection and autoimmunity by a simple barium-alginate membrane. Diabetes, 2001, 50(8), 1698-1705.
    • (2001) Diabetes , vol.50 , Issue.8 , pp. 1698-1705
    • Duvivier-Kali, V.F.1    Omer, A.2    Parent, R.J.3    O'Neil, J.J.4    Weir, G.C.5
  • 5
    • 33744496021 scopus 로고    scopus 로고
    • Six-month survival of microencapsulated pig islets and alginate biocompatibility in primates: Proof of concept
    • Dufrane, D.; Goebbels, R. M.; Saliez, A.; Guiot, Y.; Gianello, P. Six-month survival of microencapsulated pig islets and alginate biocompatibility in primates: proof of concept. Transplantation, 2006, 81(9), 1345-1353.
    • (2006) Transplantation , vol.81 , Issue.9 , pp. 1345-1353
    • Dufrane, D.1    Goebbels, R.M.2    Saliez, A.3    Guiot, Y.4    Gianello, P.5
  • 9
    • 0032970097 scopus 로고    scopus 로고
    • Treatment of type I diabetes using encapsulated islets
    • Soon-Shiong, P. Treatment of type I diabetes using encapsulated islets. Adv. Drug Deliv. Rev., 1999, 35(2-3), 259-270.
    • (1999) Adv. Drug Deliv. Rev , vol.35 , Issue.2-3 , pp. 259-270
    • Soon-Shiong, P.1
  • 10
    • 70349667312 scopus 로고    scopus 로고
    • Safety and viability of microencapsulated human islets transplanted into diabetic humans
    • Tuch, B. E.; Keogh, G. W.; Williams, L. J.; Wu, W.; Foster, J. L.; Vaithilingam, V.; Philips, R. Safety and viability of microencapsulated human islets transplanted into diabetic humans. Diabetes Care, 2009, 32(10), 1887-1889.
    • (2009) Diabetes Care , vol.32 , Issue.10 , pp. 1887-1889
    • Tuch, B.E.1    Keogh, G.W.2    Williams, L.J.3    Wu, W.4    Foster, J.L.5    Vaithilingam, V.6    Philips, R.7
  • 11
    • 0035877013 scopus 로고    scopus 로고
    • An essential role of the NF-kappa B/Toll-like receptor pathway in induction of inflammatory and tissue-repair gene expression by necrotic cells
    • Li, M.; Carpio, D. F.; Zheng, Y.; Bruzzo, P.; Singh, V.; Ouaaz, F.; Medzhitov, R. M.; Beg, A. A. An essential role of the NF-kappa B/Toll-like receptor pathway in induction of inflammatory and tissue-repair gene expression by necrotic cells. J. Immunol., 2001, 166(12), 7128-7135.
    • (2001) J. Immunol , vol.166 , Issue.12 , pp. 7128-7135
    • Li, M.1    Carpio, D.F.2    Zheng, Y.3    Bruzzo, P.4    Singh, V.5    Ouaaz, F.6    Medzhitov, R.M.7    Beg, A.A.8
  • 12
    • 0033010333 scopus 로고    scopus 로고
    • Analysis of the cellular reaction towards microencapsulated xenogeneic islets after intraperitoneal transplantation
    • Siebers, U.; Horcher, A.; Brandhorst, H.; Brandhorst, D.; Hering, B.; Federlin, K.; Bretzel, R. G.; Zekorn, T. Analysis of the cellular reaction towards microencapsulated xenogeneic islets after intraperitoneal transplantation. J. Mol. Med., 1999, 77(1), 215-218.
    • (1999) J. Mol. Med , vol.77 , Issue.1 , pp. 215-218
    • Siebers, U.1    Horcher, A.2    Brandhorst, H.3    Brandhorst, D.4    Hering, B.5    Federlin, K.6    Bretzel, R.G.7    Zekorn, T.8
  • 13
    • 56749173545 scopus 로고    scopus 로고
    • Optimal implantation site for pancreatic islet transplantation
    • Merani, S.; Toso, C.; Emamaullee, J.; Shapiro, A. M. Optimal implantation site for pancreatic islet transplantation. Br. J. Surg., 2008, 95(12), 1449-1461.
    • (2008) Br. J. Surg , vol.95 , Issue.12 , pp. 1449-1461
    • Merani, S.1    Toso, C.2    Emamaullee, J.3    Shapiro, A.M.4
  • 14
    • 0035814242 scopus 로고    scopus 로고
    • The effect of host factors and capsule composition on the cellular overgrowth on implanted alginate capsules
    • King, A.; Sandler, S.; Andersson, A. The effect of host factors and capsule composition on the cellular overgrowth on implanted alginate capsules. J Biomed. Mater. Res., 2001, 57(3), 374-383.
    • (2001) J Biomed. Mater. Res , vol.57 , Issue.3 , pp. 374-383
    • King, A.1    Sandler, S.2    Andersson, A.3
  • 15
    • 0037791563 scopus 로고    scopus 로고
    • Improvement of the biocompatibility of alginate/poly-L-lysine/alginate microcapsules by the use of epimerized alginate as a coating
    • King, A.; Strand, B.; Rokstad, A. M.; Kulseng, B.; Andersson, A.; Skjak-Braek, G.; Sandler, S. Improvement of the biocompatibility of alginate/poly-L-lysine/alginate microcapsules by the use of epimerized alginate as a coating. J. Biomed. Mater. Res., 2003, 64(3), 533-539.
    • (2003) J. Biomed. Mater. Res , vol.64 , Issue.3 , pp. 533-539
    • King, A.1    Strand, B.2    Rokstad, A.M.3    Kulseng, B.4    Andersson, A.5    Skjak-Braek, G.6    Sandler, S.7
  • 16
    • 0345346381 scopus 로고    scopus 로고
    • Transplantation of alginate microcapsules: Generation of antibodies against alginates and encapsulated porcine islet-like cell clusters
    • Kulseng, B.; Skjak-Braek, G.; Ryan, L.; Andersson, A.; King, A.; Faxvaag, A.; Espevik, T. Transplantation of alginate microcapsules: generation of antibodies against alginates and encapsulated porcine islet-like cell clusters. Transplantation, 1999, 67(7), 978-984.
    • (1999) Transplantation , vol.67 , Issue.7 , pp. 978-984
    • Kulseng, B.1    Skjak-Braek, G.2    Ryan, L.3    Andersson, A.4    King, A.5    Faxvaag, A.6    Espevik, T.7
  • 17
    • 68249095519 scopus 로고    scopus 로고
    • Biocompatibility and immune acceptance of adult porcine islets transplanted intraperitoneally in diabetic NOD mice in calcium alginate poly-L-lysine microcapsules versus barium alginate microcapsules without poly-L-lysine
    • Safley, S. A.; Cui, H.; Cauffiel, S.; Tucker-Burden, C.; Weber, C. J. Biocompatibility and immune acceptance of adult porcine islets transplanted intraperitoneally in diabetic NOD mice in calcium alginate poly-L-lysine microcapsules versus barium alginate microcapsules without poly-L-lysine. J. Diabetes Sci. Technol., 2008, 2(5), 760-767.
    • (2008) J. Diabetes Sci. Technol , vol.2 , Issue.5 , pp. 760-767
    • Safley, S.A.1    Cui, H.2    Cauffiel, S.3    Tucker-Burden, C.4    Weber, C.J.5
  • 19
    • 0031081712 scopus 로고    scopus 로고
    • Effect of the alginate composition on the biocompatibility of alginate-polylysine microcapsules
    • De Vos, P.; De Haan, B.; van Schilfgaarde, R. Effect of the alginate composition on the biocompatibility of alginate-polylysine microcapsules. Biomaterials, 1997, 18(3), 273-278.
    • (1997) Biomaterials , vol.18 , Issue.3 , pp. 273-278
    • De Vos, P.1    De Haan, B.2    van Schilfgaarde, R.3
  • 21
    • 33744543109 scopus 로고    scopus 로고
    • Effect of Ca2+, Ba2+, and Sr2+ on alginate microbeads
    • Morch, Y. A.; Donati, I.; Strand, B. L.; Skjak-Braek, G. Effect of Ca2+, Ba2+, and Sr2+ on alginate microbeads. Biomacromolecules, 2006, 7(5), 1471-1480.
    • (2006) Biomacromolecules , vol.7 , Issue.5 , pp. 1471-1480
    • Morch, Y.A.1    Donati, I.2    Strand, B.L.3    Skjak-Braek, G.4
  • 23
    • 0029777560 scopus 로고    scopus 로고
    • A rapid qualitative method to assess in vitro immunobarrier competence of pancreatic islets containing alginate/polyaminoacidic microcapsules
    • Calafiore, R.; Basta, G.; Sarchielli, P.; Luca, G.; Tortoioli, C.; Brunetti, P. A rapid qualitative method to assess in vitro immunobarrier competence of pancreatic islets containing alginate/polyaminoacidic microcapsules. Acta Diabetol., 1996, 33(2), 150-153.
    • (1996) Acta Diabetol , vol.33 , Issue.2 , pp. 150-153
    • Calafiore, R.1    Basta, G.2    Sarchielli, P.3    Luca, G.4    Tortoioli, C.5    Brunetti, P.6
  • 24
    • 23244440894 scopus 로고    scopus 로고
    • Characteristics of Poly-L-Ornithine-coated alginate microcapsules
    • Darrabie, M. D.; Kendall, W. F., Jr.; Opara, E. C. Characteristics of Poly-L-Ornithine-coated alginate microcapsules. Biomaterials, 2005, 26(34), 6846-6852.
    • (2005) Biomaterials , vol.26 , Issue.34 , pp. 6846-6852
    • Darrabie, M.D.1    Kendall Jr., W.F.2    Opara, E.C.3
  • 25
    • 0011040481 scopus 로고    scopus 로고
    • Microcapsules of alginate-chitosan. II. A study of capsule stability and permeability
    • Gaserod, O.; Sannes, A.; Skjak-Braek, G. Microcapsules of alginate-chitosan. II. A study of capsule stability and permeability. Biomaterials, 1999, 20(8), 773-783.
    • (1999) Biomaterials , vol.20 , Issue.8 , pp. 773-783
    • Gaserod, O.1    Sannes, A.2    Skjak-Braek, G.3
  • 26
    • 0030635256 scopus 로고    scopus 로고
    • New capsule with tailored properties for the encapsulation of living cells
    • Lacik, I.; Brissova, M.; Anilkumar, A. V.; Powers, A. C.; Wang, T. New capsule with tailored properties for the encapsulation of living cells. J. Biomed. Mater. Res., 1998, 39 (1), 52-60.
    • (1998) J. Biomed. Mater. Res , vol.39 , Issue.1 , pp. 52-60
    • Lacik, I.1    Brissova, M.2    Anilkumar, A.V.3    Powers, A.C.4    Wang, T.5
  • 28
    • 0030152589 scopus 로고    scopus 로고
    • Alginate polycation microcapsules. I. Interaction between alginate and polycation
    • Thu, B.; Bruheim, P.; Espevik, T.; Smidsrod, O.; Soon-Shiong, P.; Skjak-Braek, G. Alginate polycation microcapsules. I. Interaction between alginate and polycation. Biomaterials, 1996, 17(10), 1031-1040.
    • (1996) Biomaterials , vol.17 , Issue.10 , pp. 1031-1040
    • Thu, B.1    Bruheim, P.2    Espevik, T.3    Smidsrod, O.4    Soon-Shiong, P.5    Skjak-Braek, G.6
  • 29
    • 0030755661 scopus 로고    scopus 로고
    • Alginate polylysine microcapsules as immune barrier: Permeability of cytokines and immunoglobulins over the capsule membrane
    • Kulseng, B.; Thu, B.; Espevik, T.; Skjak-Braek, G. Alginate polylysine microcapsules as immune barrier: permeability of cytokines and immunoglobulins over the capsule membrane. Cell Transplant., 1997, 6(4), 387-394.
    • (1997) Cell Transplant , vol.6 , Issue.4 , pp. 387-394
    • Kulseng, B.1    Thu, B.2    Espevik, T.3    Skjak-Braek, G.4
  • 31
    • 33744932148 scopus 로고    scopus 로고
    • Cell-compatible covalently reinforced beads obtained from a chemoenzymatically engineered alginate
    • Rokstad, A. M.; Donati, I.; Borgogna, M.; Oberholzer, J.; Strand, B. L.; Espevik, T.; Skjak-Braek, G. Cell-compatible covalently reinforced beads obtained from a chemoenzymatically engineered alginate. Biomaterials, 2006, 27(27), 4726-4737.
    • (2006) Biomaterials , vol.27 , Issue.27 , pp. 4726-4737
    • Rokstad, A.M.1    Donati, I.2    Borgogna, M.3    Oberholzer, J.4    Strand, B.L.5    Espevik, T.6    Skjak-Braek, G.7
  • 33
    • 0022909916 scopus 로고
    • Future trends in biocompatibility aspects of hemodialysis and related therapies
    • Shaldon, S. Future trends in biocompatibility aspects of hemodialysis and related therapies. Clin. Nephrol., 1986, 26 Suppl 1, S13-S16.
    • (1986) Clin. Nephrol , vol.26 , Issue.SUPPL. 1
    • Shaldon, S.1
  • 34
    • 0022878980 scopus 로고
    • Clinical sequelae of complement activation in hemodialysis
    • Hakim, R. M. Clinical sequelae of complement activation in hemodialysis. Clin. Nephrol., 1986, 26 Suppl 1, S9-12.
    • (1986) Clin. Nephrol , vol.26 , Issue.SUPPL. 1
    • Hakim, R.M.1
  • 36
    • 42749096667 scopus 로고    scopus 로고
    • On the mechanisms of biocompatibility
    • Williams, D. F. On the mechanisms of biocompatibility. Biomaterials, 2008, 29(20), 2941-2953.
    • (2008) Biomaterials , vol.29 , Issue.20 , pp. 2941-2953
    • Williams, D.F.1
  • 37
    • 81855222098 scopus 로고    scopus 로고
    • The biocompatibility manifesto: Biocompatibility for the twenty-first century
    • Ratner, B. D. The biocompatibility manifesto: biocompatibility for the twenty-first century. J. Cardiovasc. Transl. Res., 2011, 4(5), 523-527.
    • (2011) J. Cardiovasc. Transl. Res , vol.4 , Issue.5 , pp. 523-527
    • Ratner, B.D.1
  • 38
    • 0031872493 scopus 로고    scopus 로고
    • Complement and biocompatibility
    • Mollnes, T. E. Complement and biocompatibility. Vox Sang., 1998, 74 Suppl 2, 303-307.
    • (1998) Vox Sang , vol.74 , Issue.SUPPL. 2 , pp. 303-307
    • Mollnes, T.E.1
  • 40
    • 17644388462 scopus 로고    scopus 로고
    • Role of C5a in inflammatory responses
    • Guo, R. F.; Ward, P. A. Role of C5a in inflammatory responses. Annu. Rev. Immunol., 2005, 23, 821-852.
    • (2005) Annu. Rev. Immunol , vol.23 , pp. 821-852
    • Guo, R.F.1    Ward, P.A.2
  • 41
    • 84868156108 scopus 로고    scopus 로고
    • Regulation of tissue factor coagulant activity on cell surfaces
    • Rao, L. V.; Pendurthi, U. R. Regulation of tissue factor coagulant activity on cell surfaces. J. Thromb. Haemost., 2012, 10(11), 2242-2253.
    • (2012) J. Thromb. Haemost , vol.10 , Issue.11 , pp. 2242-2253
    • Rao, L.V.1    Pendurthi, U.R.2
  • 43
    • 77949269053 scopus 로고    scopus 로고
    • Tissue factor expression in blood cells
    • Osterud, B. Tissue factor expression in blood cells. Thromb. Res., 2010, 125 Suppl 1, S31-S34.
    • (2010) Thromb. Res , vol.125 , Issue.SUPPL. 1
    • Osterud, B.1
  • 44
    • 0028846781 scopus 로고
    • A novel biological effect of platelet factor 4 (PF4): Enhancement of LPSinduced tissue factor activity in monocytes
    • Engstad, C. S.; Lia, K.; Rekdal, O.; Olsen, J. O.; Osterud, B. A novel biological effect of platelet factor 4 (PF4): enhancement of LPSinduced tissue factor activity in monocytes. J. Leukoc. Biol., 1995, 58(5), 575-581.
    • (1995) J. Leukoc. Biol , vol.58 , Issue.5 , pp. 575-581
    • Engstad, C.S.1    Lia, K.2    Rekdal, O.3    Olsen, J.O.4    Osterud, B.5
  • 45
    • 84934438226 scopus 로고    scopus 로고
    • The Effects of Selective Complement and CD14 Inhibition on the E. coli-Induced Tissue Factor mRNA Upregulation, Monocyte Tissue Factor Expression, and Tissue Factor Functional Activity in Human Whole Blood
    • Brekke, O. L.; Waage, C.; Christiansen, D.; Fure, H.; Qu, H.; Lambris, J. D.; Osterud, B.; Nielsen, E. W.; Mollnes, T. E. The Effects of Selective Complement and CD14 Inhibition on the E. coli-Induced Tissue Factor mRNA Upregulation, Monocyte Tissue Factor Expression, and Tissue Factor Functional Activity in Human Whole Blood. Adv. Exp. Med. Biol., 2013, 734, 123-136.
    • (2013) Adv. Exp. Med. Biol , vol.734 , pp. 123-136
    • Brekke, O.L.1    Waage, C.2    Christiansen, D.3    Fure, H.4    Qu, H.5    Lambris, J.D.6    Osterud, B.7    Nielsen, E.W.8    Mollnes, T.E.9
  • 46
    • 48449101517 scopus 로고    scopus 로고
    • Circulating tissue factor-exposing microparticles
    • Lechner, D.; Weltermann, A. Circulating tissue factor-exposing microparticles. Thromb. Res., 2008, 122 Suppl 1, S47-S54.
    • (2008) Thromb. Res , vol.122 , Issue.SUPPL. 1
    • Lechner, D.1    Weltermann, A.2
  • 47
    • 84857532767 scopus 로고    scopus 로고
    • Interactions between coagulation and complement--their role in inflammation
    • Oikonomopoulou, K.; Ricklin, D.; Ward, P. A.; Lambris, J. D. Interactions between coagulation and complement--their role in inflammation. Semin. Immunopathol., 2012, 34(1), 151-165.
    • (2012) Semin. Immunopathol , vol.34 , Issue.1 , pp. 151-165
    • Oikonomopoulou, K.1    Ricklin, D.2    Ward, P.A.3    Lambris, J.D.4
  • 52
    • 84859698558 scopus 로고    scopus 로고
    • The roles of thrombin and protease-activated receptors in inflammation
    • Ma, L.; Dorling, A. The roles of thrombin and protease-activated receptors in inflammation. Semin. Immunopathol., 2012, 34(1), 63-72.
    • (2012) Semin. Immunopathol , vol.34 , Issue.1 , pp. 63-72
    • Ma, L.1    Dorling, A.2
  • 53
    • 0032529677 scopus 로고    scopus 로고
    • Thrombinactivated human endothelial cells support monocyte adhesion in vitro following expression of intercellular adhesion molecule-1 (ICAM-1; CD54) and vascular cell adhesion molecule-1 (VCAM-1; CD106)
    • Kaplanski, G.; Marin, V.; Fabrigoule, M.; Boulay, V.; Benoliel, A. M.; Bongrand, P.; Kaplanski, S.; Farnarier, C. Thrombinactivated human endothelial cells support monocyte adhesion in vitro following expression of intercellular adhesion molecule-1 (ICAM-1; CD54) and vascular cell adhesion molecule-1 (VCAM-1; CD106). Blood, 1998, 92(4), 1259-1267.
    • (1998) Blood , vol.92 , Issue.4 , pp. 1259-1267
    • Kaplanski, G.1    Marin, V.2    Fabrigoule, M.3    Boulay, V.4    Benoliel, A.M.5    Bongrand, P.6    Kaplanski, S.7    Farnarier, C.8
  • 54
    • 0036464689 scopus 로고    scopus 로고
    • Roles for thrombin and fibrin(ogen) in cytokine/chemokine production and macrophage adhesion in vivo
    • Szaba, F. M.; Smiley, S. T. Roles for thrombin and fibrin(ogen) in cytokine/chemokine production and macrophage adhesion in vivo. Blood, 2002, 99(3), 1053-1059.
    • (2002) Blood , vol.99 , Issue.3 , pp. 1053-1059
    • Szaba, F.M.1    Smiley, S.T.2
  • 55
    • 0005746001 scopus 로고    scopus 로고
    • Phosphorylation of coagulation factor XI by a casein kinase released by activated human platelets increases its susceptibility to activation by factor XIIa and thrombin
    • Ekdahl, K. N.; Elgue, G.; Nilsson, B. Phosphorylation of coagulation factor XI by a casein kinase released by activated human platelets increases its susceptibility to activation by factor XIIa and thrombin. Thromb. Haemost., 1999, 82(4), 1283-1288.
    • (1999) Thromb. Haemost , vol.82 , Issue.4 , pp. 1283-1288
    • Ekdahl, K.N.1    Elgue, G.2    Nilsson, B.3
  • 57
    • 84870439456 scopus 로고    scopus 로고
    • Platelets: Key players in vascular inflammation
    • Projahn, D.; Koenen, R. R. Platelets: key players in vascular inflammation. J. Leukoc. Biol., 2012, 92(6), 1167-1175.
    • (2012) J. Leukoc. Biol , vol.92 , Issue.6 , pp. 1167-1175
    • Projahn, D.1    Koenen, R.R.2
  • 59
    • 84865511829 scopus 로고    scopus 로고
    • Plasmin as a proinflammatory cell activator
    • Syrovets, T.; Lunov, O.; Simmet, T. Plasmin as a proinflammatory cell activator. J. Leukoc. Biol., 2012, 92(3), 509-519.
    • (2012) J. Leukoc. Biol , vol.92 , Issue.3 , pp. 509-519
    • Syrovets, T.1    Lunov, O.2    Simmet, T.3
  • 60
    • 84862804952 scopus 로고    scopus 로고
    • Accessory molecules for Toll-like receptors and their function
    • Lee, C. C.; Avalos, A. M.; Ploegh, H. L. Accessory molecules for Toll-like receptors and their function. Nat. Rev. Immunol., 2012, 12(3), 168-179.
    • (2012) Nat. Rev. Immunol , vol.12 , Issue.3 , pp. 168-179
    • Lee, C.C.1    Avalos, A.M.2    Ploegh, H.L.3
  • 61
  • 63
    • 47649090540 scopus 로고    scopus 로고
    • Complement activation triggered by chondroitin sulfate released by thrombin receptor-activated platelets
    • Hamad, O. A.; Ekdahl, K. N.; Nilsson, P. H.; Andersson, J.; Magotti, P.; Lambris, J. D.; Nilsson, B. Complement activation triggered by chondroitin sulfate released by thrombin receptor-activated platelets. J. Thromb. Haemost., 2008, 6(8), 1413-1421.
    • (2008) J. Thromb. Haemost , vol.6 , Issue.8 , pp. 1413-1421
    • Hamad, O.A.1    Ekdahl, K.N.2    Nilsson, P.H.3    Andersson, J.4    Magotti, P.5    Lambris, J.D.6    Nilsson, B.7
  • 64
    • 84866050890 scopus 로고    scopus 로고
    • Complement and dysbiosis in periodontal disease
    • Hajishengallis, G.; Lambris, J. D. Complement and dysbiosis in periodontal disease. Immunobiology, 2012, 217(11), 1111-1116.
    • (2012) Immunobiology , vol.217 , Issue.11 , pp. 1111-1116
    • Hajishengallis, G.1    Lambris, J.D.2
  • 65
    • 84866033089 scopus 로고    scopus 로고
    • Interactions of the complement system with molecules of extracellular matrix: Relevance for joint diseases
    • Happonen, K. E.; Heinegard, D.; Saxne, T.; Blom, A. M. Interactions of the complement system with molecules of extracellular matrix: Relevance for joint diseases. Immunobiology, 2012, 217(11), 1088-1096.
    • (2012) Immunobiology , vol.217 , Issue.11 , pp. 1088-1096
    • Happonen, K.E.1    Heinegard, D.2    Saxne, T.3    Blom, A.M.4
  • 66
    • 84866017430 scopus 로고    scopus 로고
    • The immunoglobulin, IgG Fc receptor and complement triangle in autoimmune diseases
    • Karsten, C. M.; Kohl, J. The immunoglobulin, IgG Fc receptor and complement triangle in autoimmune diseases. Immunobiology, 2012, 217 (11), 1067-1079.
    • (2012) Immunobiology , vol.217 , Issue.11 , pp. 1067-1079
    • Karsten, C.M.1    Kohl, J.2
  • 67
    • 52949118458 scopus 로고    scopus 로고
    • Harmful molecular mechanisms in sepsis
    • Rittirsch, D.; Flierl, M. A.; Ward, P. A. Harmful molecular mechanisms in sepsis. Nat. Rev. Immunol., 2008, 8(10), 776-787.
    • (2008) Nat. Rev. Immunol , vol.8 , Issue.10 , pp. 776-787
    • Rittirsch, D.1    Flierl, M.A.2    Ward, P.A.3
  • 69
    • 77950187449 scopus 로고    scopus 로고
    • Crosstalk pathways between Tolllike receptors and the complement system
    • Hajishengallis, G.; Lambris, J. D. Crosstalk pathways between Tolllike receptors and the complement system. Trends Immunol., 2010, 31(4), 154-163.
    • (2010) Trends Immunol , vol.31 , Issue.4 , pp. 154-163
    • Hajishengallis, G.1    Lambris, J.D.2
  • 70
    • 73149108627 scopus 로고    scopus 로고
    • Can cells and biomaterials in therapeutic medicine be shielded from innate immune recognition?
    • Nilsson, B.; Korsgren, O.; Lambris, J. D.; Ekdahl, K. N. Can cells and biomaterials in therapeutic medicine be shielded from innate immune recognition? Trends Immunol., 2010, 31(1), 32-38.
    • (2010) Trends Immunol , vol.31 , Issue.1 , pp. 32-38
    • Nilsson, B.1    Korsgren, O.2    Lambris, J.D.3    Ekdahl, K.N.4
  • 71
    • 0030893168 scopus 로고    scopus 로고
    • Modulation of blood cell activation by four commonly used anticoagulants
    • Engstad, C. S.; Gutteberg, T. J.; Osterud, B. Modulation of blood cell activation by four commonly used anticoagulants. Thromb. Haemost., 1997, 77(4), 690-696.
    • (1997) Thromb. Haemost , vol.77 , Issue.4 , pp. 690-696
    • Engstad, C.S.1    Gutteberg, T.J.2    Osterud, B.3
  • 72
    • 0036721025 scopus 로고    scopus 로고
    • Essential role of the C5a receptor in E coli-induced oxidative burst and phagocytosis revealed by a novel lepirudin based human whole blood model of inflammation
    • Mollnes, T. E.; Brekke, O. L.; Fung, M.; Fure, H.; Christiansen, D.; Bergseth, G.; Videm, V.; Lappegard, K. T.; Kohl, J.; Lambris, J. D. Essential role of the C5a receptor in E coli-induced oxidative burst and phagocytosis revealed by a novel lepirudin based human whole blood model of inflammation. Blood, 2002, 100(5), 1869-1877.
    • (2002) Blood , vol.100 , Issue.5 , pp. 1869-1877
    • Mollnes, T.E.1    Brekke, O.L.2    Fung, M.3    Fure, H.4    Christiansen, D.5    Bergseth, G.6    Videm, V.7    Lappegard, K.T.8    Kohl, J.9    Lambris, J.D.10
  • 73
    • 80052160688 scopus 로고    scopus 로고
    • Advances in assay of complement function and activation
    • Harboe, M.; Thorgersen, E. B.; Mollnes, T. E. Advances in assay of complement function and activation. Adv. Drug Deliv. Rev., 2011, 63(12), 976-987.
    • (2011) Adv. Drug Deliv. Rev , vol.63 , Issue.12 , pp. 976-987
    • Harboe, M.1    Thorgersen, E.B.2    Mollnes, T.E.3
  • 76
    • 0022898222 scopus 로고
    • Prothrombin fragment 1 X 2 X 3, a major product of prothrombin activation in human plasma
    • Rabiet, M. J.; Blashill, A.; Furie, B.; Furie, B. C. Prothrombin fragment 1 X 2 X 3, a major product of prothrombin activation in human plasma. J. Biol. Chem., 1986, 261(28), 13210-13215.
    • (1986) J. Biol. Chem , vol.261 , Issue.28 , pp. 13210-13215
    • Rabiet, M.J.1    Blashill, A.2    Furie, B.3    Furie, B.C.4
  • 78
    • 0020662680 scopus 로고
    • Chemotactic response of monocytes to thrombin
    • Bar-Shavit, R.; Kahn, A.; Fenton, J. W.; Wilner, G. D. Chemotactic response of monocytes to thrombin. J. Cell Biol., 1983, 96(1), 282-285.
    • (1983) J. Cell Biol , vol.96 , Issue.1 , pp. 282-285
    • Bar-Shavit, R.1    Kahn, A.2    Fenton, J.W.3    Wilner, G.D.4
  • 79
    • 0029996796 scopus 로고    scopus 로고
    • The proinflammatory cytokine response to coagulation and endotoxin in whole blood
    • Johnson, K.; Aarden, L.; Choi, Y.; De, G. E.; Creasey, A. The proinflammatory cytokine response to coagulation and endotoxin in whole blood. Blood, 1996, 87(12), 5051-5060.
    • (1996) Blood , vol.87 , Issue.12 , pp. 5051-5060
    • Johnson, K.1    Aarden, L.2    Choi, Y.3    De, G.E.4    Creasey, A.5
  • 80
    • 0030036714 scopus 로고    scopus 로고
    • Thrombin potently stimulates cytokine production in human vascular smooth muscle cells but not in mononuclear phagocytes
    • Kranzhofer, R.; Clinton, S. K.; Ishii, K.; Coughlin, S. R.; Fenton, J. W.; Libby, P. Thrombin potently stimulates cytokine production in human vascular smooth muscle cells but not in mononuclear phagocytes. Circ. Res., 1996, 79(2), 286-294.
    • (1996) Circ. Res , vol.79 , Issue.2 , pp. 286-294
    • Kranzhofer, R.1    Clinton, S.K.2    Ishii, K.3    Coughlin, S.R.4    Fenton, J.W.5    Libby, P.6
  • 82
    • 0347384110 scopus 로고    scopus 로고
    • Optimal heparin surface concentration and antithrombin binding capacity as evaluated with human nonanticoagulated blood in vitro
    • Andersson, J.; Sanchez, J.; Ekdahl, K. N.; Elgue, G.; Nilsson, B.; Larsson, R. Optimal heparin surface concentration and antithrombin binding capacity as evaluated with human nonanticoagulated blood in vitro. J. Biomed. Mater. Res. A., 2003, 67(2), 458-466.
    • (2003) J. Biomed. Mater. Res. A , vol.67 , Issue.2 , pp. 458-466
    • Andersson, J.1    Sanchez, J.2    Ekdahl, K.N.3    Elgue, G.4    Nilsson, B.5    Larsson, R.6
  • 83
    • 0034653591 scopus 로고    scopus 로고
    • Damage to porcine islets of Langerhans after exposure to human blood in vitro, or after intraportal transplantation to cynomologus monkeys: Protective effects of sCR1 and heparin
    • Bennet, W.; Sundberg, B.; Lundgren, T.; Tibell, A.; Groth, C. G.; Richards, A.; White, D. J.; Elgue, G.; Larsson, R.; Nilsson, B.; Korsgren, O. Damage to porcine islets of Langerhans after exposure to human blood in vitro, or after intraportal transplantation to cynomologus monkeys: protective effects of sCR1 and heparin. Transplantation, 2000, 69(5), 711-719.
    • (2000) Transplantation , vol.69 , Issue.5 , pp. 711-719
    • Bennet, W.1    Sundberg, B.2    Lundgren, T.3    Tibell, A.4    Groth, C.G.5    Richards, A.6    White, D.J.7    Elgue, G.8    Larsson, R.9    Nilsson, B.10    Korsgren, O.11
  • 85
    • 0029924746 scopus 로고    scopus 로고
    • Tubing loops as a model for cardiopulmonary bypass circuits: Both the biomaterial and the blood-gas phase interfaces induce complement activation in an in vitro model
    • Gong, J.; Larsson, R.; Ekdahl, K. N.; Mollnes, T. E.; Nilsson, U.; Nilsson, B. Tubing loops as a model for cardiopulmonary bypass circuits: both the biomaterial and the blood-gas phase interfaces induce complement activation in an in vitro model. J. Clin. Immunol., 1996, 16(4), 222-229.
    • (1996) J. Clin. Immunol , vol.16 , Issue.4 , pp. 222-229
    • Gong, J.1    Larsson, R.2    Ekdahl, K.N.3    Mollnes, T.E.4    Nilsson, U.5    Nilsson, B.6
  • 86
    • 0027551670 scopus 로고
    • Complement activation by polymethyl methacrylate minimized by end-point heparin attachment
    • Pekna, M.; Larsson, R.; Formgren, B.; Nilsson, U. R.; Nilsson, B. Complement activation by polymethyl methacrylate minimized by end-point heparin attachment. Biomaterials, 1993, 14(3), 189-192.
    • (1993) Biomaterials , vol.14 , Issue.3 , pp. 189-192
    • Pekna, M.1    Larsson, R.2    Formgren, B.3    Nilsson, U.R.4    Nilsson, B.5
  • 87
    • 34249681296 scopus 로고    scopus 로고
    • The role of complement C3 opsonization, C5a receptor, and CD14 in E. coli-induced up-regulation of granulocyte and monocyte CD11b/CD18 (CR3), phagocytosis, and oxidative burst in human whole blood
    • Brekke, O. L.; Christiansen, D.; Fure, H.; Fung, M.; Mollnes, T. E. The role of complement C3 opsonization, C5a receptor, and CD14 in E. coli-induced up-regulation of granulocyte and monocyte CD11b/CD18 (CR3), phagocytosis, and oxidative burst in human whole blood. J. Leukoc. Biol., 2007, 81(6), 1404-1413.
    • (2007) J. Leukoc. Biol , vol.81 , Issue.6 , pp. 1404-1413
    • Brekke, O.L.1    Christiansen, D.2    Fure, H.3    Fung, M.4    Mollnes, T.E.5
  • 88
    • 80555133248 scopus 로고    scopus 로고
    • Differential effect of inhibiting MD-2 and CD14 on LPS-versus whole E. coli bacteria-induced cytokine responses in human blood
    • Christiansen, D.; Brekke, O. L.; Stenvik, J.; Lambris, J. D.; Espevik, T.; Mollnes, T. E. Differential effect of inhibiting MD-2 and CD14 on LPS-versus whole E. coli bacteria-induced cytokine responses in human blood. Adv. Exp. Med. Biol., 2012, 946, 237-251.
    • (2012) Adv. Exp. Med. Biol , vol.946 , pp. 237-251
    • Christiansen, D.1    Brekke, O.L.2    Stenvik, J.3    Lambris, J.D.4    Espevik, T.5    Mollnes, T.E.6
  • 90
    • 60549098794 scopus 로고    scopus 로고
    • Inhibition of complement and CD14 attenuates the Escherichia coli-induced inflammatory response in porcine whole blood
    • Thorgersen, E. B.; Pharo, A.; Haverson, K.; Axelsen, A. K.; Gaustad, P.; Kotwal, G. J.; Sfyroera, G.; Mollnes, T. E. Inhibition of complement and CD14 attenuates the Escherichia coli-induced inflammatory response in porcine whole blood. Infect. Immun., 2009, 77(2), 725-732.
    • (2009) Infect. Immun , vol.77 , Issue.2 , pp. 725-732
    • Thorgersen, E.B.1    Pharo, A.2    Haverson, K.3    Axelsen, A.K.4    Gaustad, P.5    Kotwal, G.J.6    Sfyroera, G.7    Mollnes, T.E.8
  • 91
    • 48049089596 scopus 로고    scopus 로고
    • Combined inhibition of complement and CD14 abolish E. coli-induced cytokine-, chemokine-and growth factor-synthesis in human whole blood
    • Brekke, O. L.; Christiansen, D.; Fure, H.; Pharo, A.; Fung, M.; Riesenfeld, J.; Mollnes, T. E. Combined inhibition of complement and CD14 abolish E. coli-induced cytokine-, chemokine-and growth factor-synthesis in human whole blood. Mol. Immunol., 2008, 45(14), 3804-3813.
    • (2008) Mol. Immunol , vol.45 , Issue.14 , pp. 3804-3813
    • Brekke, O.L.1    Christiansen, D.2    Fure, H.3    Pharo, A.4    Fung, M.5    Riesenfeld, J.6    Mollnes, T.E.7
  • 92
    • 22244479716 scopus 로고    scopus 로고
    • Role of granulocytes and monocytes in the polyvinyl chlorideinduced synthesis of interleukin 8, monocyte chemoattractant protein 1, and leukotriene B4
    • Lappegard, K. T.; Bergseth, G.; Riesenfeld, J.; Sexton, J.; Mollnes, T. E. Role of granulocytes and monocytes in the polyvinyl chlorideinduced synthesis of interleukin 8, monocyte chemoattractant protein 1, and leukotriene B4. J. Biomed. Mater. Res. A., 2005, 74(2), 230-236.
    • (2005) J. Biomed. Mater. Res. A , vol.74 , Issue.2 , pp. 230-236
    • Lappegard, K.T.1    Bergseth, G.2    Riesenfeld, J.3    Sexton, J.4    Mollnes, T.E.5
  • 93
    • 51849090918 scopus 로고    scopus 로고
    • The artificial surface-induced whole blood inflammatory reaction revealed by increases in a series of chemokines and growth factors is largely complement dependent
    • Lappegard, K. T.; Bergseth, G.; Riesenfeld, J.; Pharo, A.; Magotti, P.; Lambris, J. D.; Mollnes, T. E. The artificial surface-induced whole blood inflammatory reaction revealed by increases in a series of chemokines and growth factors is largely complement dependent. J. Biomed. Mater. Res. A., 2008, 87(1), 129-135.
    • (2008) J. Biomed. Mater. Res. A , vol.87 , Issue.1 , pp. 129-135
    • Lappegard, K.T.1    Bergseth, G.2    Riesenfeld, J.3    Pharo, A.4    Magotti, P.5    Lambris, J.D.6    Mollnes, T.E.7
  • 94
    • 3042586752 scopus 로고    scopus 로고
    • Artificial surface-induced cytokine synthesis: Effect of heparin coating and complement inhibition
    • Lappegard, K. T.; Fung, M.; Bergseth, G.; Riesenfeld, J.; Mollnes, T. E. Artificial surface-induced cytokine synthesis: effect of heparin coating and complement inhibition. Ann. Thorac. Surg., 2004, 78(1), 38-44.
    • (2004) Ann. Thorac. Surg , vol.78 , Issue.1 , pp. 38-44
    • Lappegard, K.T.1    Fung, M.2    Bergseth, G.3    Riesenfeld, J.4    Mollnes, T.E.5
  • 96
    • 84859099901 scopus 로고    scopus 로고
    • Inflammatory response induced by candidate biomaterials of an implantable microfabricated sensor
    • Sokolov, A.; Hellerud, B. C.; Johannessen, E. A.; Mollnes, T. E. Inflammatory response induced by candidate biomaterials of an implantable microfabricated sensor. J. Biomed. Mater. Res. A., 2012, 100(5), 1142-1150.
    • (2012) J. Biomed. Mater. Res. A , vol.100 , Issue.5 , pp. 1142-1150
    • Sokolov, A.1    Hellerud, B.C.2    Johannessen, E.A.3    Mollnes, T.E.4
  • 97
    • 78751676380 scopus 로고    scopus 로고
    • Artificial surface-induced inflammation relies on complement factor 5: Proof from a deficient person
    • Bergseth, G.; Lambris, J. D.; Mollnes, T. E.; Lappegard, K. T. Artificial surface-induced inflammation relies on complement factor 5: proof from a deficient person. Ann. Thorac. Surg., 2011, 91(2), 527-533.
    • (2011) Ann. Thorac. Surg , vol.91 , Issue.2 , pp. 527-533
    • Bergseth, G.1    Lambris, J.D.2    Mollnes, T.E.3    Lappegard, K.T.4
  • 99
    • 0027408771 scopus 로고
    • Modification of the complement binding properties of polystyrene: Effects of end-point heparin attachment
    • Nilsson, U. R.; Larm, O.; Nilsson, B.; Storm, K. E.; Elwing, H.; Nilsson, E. K. Modification of the complement binding properties of polystyrene: effects of end-point heparin attachment. Scand. J. Immunol., 1993, 37(3), 349-354.
    • (1993) Scand. J. Immunol , vol.37 , Issue.3 , pp. 349-354
    • Nilsson, U.R.1    Larm, O.2    Nilsson, B.3    Storm, K.E.4    Elwing, H.5    Nilsson, E.K.6
  • 100
    • 9644280856 scopus 로고    scopus 로고
    • The quantitative role of alternative pathway amplification in classical pathway induced terminal complement activation
    • Harboe, M.; Ulvund, G.; Vien, L.; Fung, M.; Mollnes, T. E. The quantitative role of alternative pathway amplification in classical pathway induced terminal complement activation. Clin. Exp. Immunol., 2004, 138 (3), 439-446.
    • (2004) Clin. Exp. Immunol , vol.138 , Issue.3 , pp. 439-446
    • Harboe, M.1    Ulvund, G.2    Vien, L.3    Fung, M.4    Mollnes, T.E.5
  • 101
    • 33744461802 scopus 로고    scopus 로고
    • Design of a complement mannose-binding lectin pathway-specific activation system applicable at low serum dilutions
    • Harboe, M.; Garred, P.; Borgen, M. S.; Stahl, G. L.; Roos, A.; Mollnes, T. E. Design of a complement mannose-binding lectin pathway-specific activation system applicable at low serum dilutions. Clin. Exp. Immunol., 2006, 144(3), 512-520.
    • (2006) Clin. Exp. Immunol , vol.144 , Issue.3 , pp. 512-520
    • Harboe, M.1    Garred, P.2    Borgen, M.S.3    Stahl, G.L.4    Roos, A.5    Mollnes, T.E.6
  • 102
    • 7444238105 scopus 로고    scopus 로고
    • Binding of C3 fragments on top of adsorbed plasma proteins during complement activation on a model biomaterial surface
    • Andersson, J.; Ekdahl, K. N.; Lambris, J. D.; Nilsson, B. Binding of C3 fragments on top of adsorbed plasma proteins during complement activation on a model biomaterial surface. Biomaterials, 2005, 26(13), 1477-1485.
    • (2005) Biomaterials , vol.26 , Issue.13 , pp. 1477-1485
    • Andersson, J.1    Ekdahl, K.N.2    Lambris, J.D.3    Nilsson, B.4
  • 103
    • 37549023083 scopus 로고    scopus 로고
    • Complement driven by conformational changes
    • Gros, P.; Milder, F. J.; Janssen, B. J. Complement driven by conformational changes. Nat. Rev. Immunol., 2008, 8(1), 48-58.
    • (2008) Nat. Rev. Immunol , vol.8 , Issue.1 , pp. 48-58
    • Gros, P.1    Milder, F.J.2    Janssen, B.J.3
  • 104
    • 0028784590 scopus 로고
    • A new model for evaluation of biocompatibility: Combined determination of neoepitopes in blood and on artificial surfaces demonstrates reduced complement activation by immobilization of heparin
    • Mollnes, T. E.; Riesenfeld, J.; Garred, P.; Nordstrom, E.; Hogasen, K.; Fosse, E.; Gotze, O.; Harboe, M. A new model for evaluation of biocompatibility: combined determination of neoepitopes in blood and on artificial surfaces demonstrates reduced complement activation by immobilization of heparin. Artif. Organs, 1995, 19(9), 909-917.
    • (1995) Artif. Organs , vol.19 , Issue.9 , pp. 909-917
    • Mollnes, T.E.1    Riesenfeld, J.2    Garred, P.3    Nordstrom, E.4    Hogasen, K.5    Fosse, E.6    Gotze, O.7    Harboe, M.8
  • 105
    • 0015093323 scopus 로고
    • In vivo effects of cellulose sulphate on plasma kininogen, complement and inflammation
    • Eisen, V.; Loveday, C. In vivo effects of cellulose sulphate on plasma kininogen, complement and inflammation. Br. J. Pharmacol., 1971, 42(3), 383-391.
    • (1971) Br. J. Pharmacol , vol.42 , Issue.3 , pp. 383-391
    • Eisen, V.1    Loveday, C.2
  • 107
    • 0021856788 scopus 로고
    • Bactericidal activity of ascitic fluid in patients with nephrotic syndrome
    • Akalin, H. E.; Fisher, K. A.; Laleli, Y.; Caglar, S. Bactericidal activity of ascitic fluid in patients with nephrotic syndrome. Eur. J. Clin. Invest., 1985, 15(3), 138-140.
    • (1985) Eur. J. Clin. Invest , vol.15 , Issue.3 , pp. 138-140
    • Akalin, H.E.1    Fisher, K.A.2    Laleli, Y.3    Caglar, S.4
  • 108
    • 79960371481 scopus 로고    scopus 로고
    • Structural surface changes and inflammatory responses against alginate-based microcapsules after exposure to human peritoneal fluid
    • De Haan, B. J.; Rossi, A.; Faas, M. M.; Smelt, M. J.; Sonvico, F.; Colombo, P.; de, V. P. Structural surface changes and inflammatory responses against alginate-based microcapsules after exposure to human peritoneal fluid. J. Biomed. Mater. Res. A., 2011, 98(3), 394-403.
    • (2011) J. Biomed. Mater. Res. A , vol.98 , Issue.3 , pp. 394-403
    • De Haan, B.J.1    Rossi, A.2    Faas, M.M.3    Smelt, M.J.4    Sonvico, F.5    Colombo, P.6    De, V.P.7
  • 111
    • 59249105532 scopus 로고    scopus 로고
    • Dual role of complement in adipose tissue
    • Pattrick, M.; Luckett, J.; Yue, L.; Stover, C. Dual role of complement in adipose tissue. Mol. Immunol., 2009, 46(5), 755-760.
    • (2009) Mol. Immunol , vol.46 , Issue.5 , pp. 755-760
    • Pattrick, M.1    Luckett, J.2    Yue, L.3    Stover, C.4
  • 112
    • 33748992313 scopus 로고    scopus 로고
    • Adipocytokines: Mediators linking adipose tissue, inflammation and immunity
    • Tilg, H.; Moschen, A. R. Adipocytokines: mediators linking adipose tissue, inflammation and immunity. Nat. Rev. Immunol., 2006, 6(10), 772-783.
    • (2006) Nat. Rev. Immunol , vol.6 , Issue.10 , pp. 772-783
    • Tilg, H.1    Moschen, A.R.2
  • 113
    • 63049112908 scopus 로고    scopus 로고
    • Innate immunity and adipocyte function: Ligand-specific activation of multiple Toll-like receptors modulates cytokine, adipokine, and chemokine secretion in adipocytes
    • Kopp, A.; Buechler, C.; Neumeier, M.; Weigert, J.; Aslanidis, C.; Scholmerich, J.; Schaffler, A. Innate immunity and adipocyte function: ligand-specific activation of multiple Toll-like receptors modulates cytokine, adipokine, and chemokine secretion in adipocytes. Obesity. (Silver. Spring), 2009, 17(4), 648-656.
    • (2009) Obesity. (Silver. Spring) , vol.17 , Issue.4 , pp. 648-656
    • Kopp, A.1    Buechler, C.2    Neumeier, M.3    Weigert, J.4    Aslanidis, C.5    Scholmerich, J.6    Schaffler, A.7
  • 114
    • 33644828305 scopus 로고    scopus 로고
    • Chemokines and chemokine receptors: Their manifold roles in homeostasis and disease
    • Le, Y.; Zhou, Y.; Iribarren, P.; Wang, J. Chemokines and chemokine receptors: their manifold roles in homeostasis and disease. Cell Mol. Immunol., 2004, 1(2), 95-104.
    • (2004) Cell Mol. Immunol , vol.1 , Issue.2 , pp. 95-104
    • Le, Y.1    Zhou, Y.2    Iribarren, P.3    Wang, J.4


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