Dihydroartemisinin (DHA) treatment causes an arrest of cell division and apoptosis in rat embryonic erythroblasts in whole embryo culture

Birth Defects Research Part B - Developmental and Reproductive Toxicology

Volumn 98, Issue 6, 2013, Pages 445-458

  Posobiec, Lorraine M ^a   Clark, Robert L ^b   Bushdid, Paul B ^a   Laffan, Susan B ^a   Wang, Kai Fen ^a   White, Tacey E K ^c  

^a GLAXOSMITHKLINE   (United States)

^b Artemis Pharmaceutical Research   (United States)

^c EXPONENT INC   (United States)

Author keywords

Artesunate; Dihydroartemisinin; Embryogenesis; Erythroblast; Erythrocyte; Rat; Teratogen; Whole embryo culture

Indexed keywords

DIHYDROARTEMISININ;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BLOOD CELL; CELL CYCLE ARREST; CELL DIVISION; CONTROLLED STUDY; EMBRYO; EMBRYO CULTURE; ERYTHROBLAST; NONHUMAN; PRIORITY JOURNAL; RAT; YOLK SAC;

ARTESUNATE; RATTUS;

ARTESUNATE; DIHYDROARTEMISININ; EMBRYOGENESIS; ERYTHROBLAST; ERYTHROCYTE; RAT; TERATOGEN; WHOLE EMBRYO CULTURE;

ANIMALS; ANTIMALARIALS; APOPTOSIS; ARTEMISININS; CASPASE 3; CELL CYCLE CHECKPOINTS; CELL DIVISION; EMBRYO CULTURE TECHNIQUES; EMBRYO, MAMMALIAN; EMBRYONIC DEVELOPMENT; ERYTHROBLASTS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84892955870     PISSN: 15429733     EISSN: 15429741     Source Type: Journal    
DOI: 10.1002/bdrb.21088     Document Type: Article

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