메뉴 건너뛰기




Volumn 4, Issue 1, 2013, Pages

The Sex Chromosome Trisomy mouse model of XXY and XYY: Metabolism and motor performance

Author keywords

Body weight; Klinefelter; Mouse; Obesity; Sex chromosome trisomy; X chromosome; XXY; XYY; Y chromosome

Indexed keywords


EID: 84892918755     PISSN: None     EISSN: 20426410     Source Type: Journal    
DOI: 10.1186/2042-6410-4-15     Document Type: Article
Times cited : (31)

References (85)
  • 1
    • 85003166195 scopus 로고
    • Syndrome characterized by gynecomastia, aspermatogenesis without aleydigism, and increase excretion of follicle-stimulating hormone
    • Klinefelter HF, Reifenstein EC, Albright F: Syndrome characterized by gynecomastia, aspermatogenesis without aleydigism, and increase excretion of follicle-stimulating hormone. J Clin Endocr 1942, 2:615-627.
    • (1942) J Clin Endocr , vol.2 , pp. 615-627
    • Klinefelter, H.F.1    Reifenstein, E.C.2    Albright, F.3
  • 2
    • 33747686159 scopus 로고
    • A case of human intersexuality having a possible XXY sex-determining mechanism
    • Jacobs PA, Strong JA: A case of human intersexuality having a possible XXY sex-determining mechanism. Nat 1959, 183:302-303.
    • (1959) Nat , vol.183 , pp. 302-303
    • Jacobs, P.A.1    Strong, J.A.2
  • 3
    • 0030948448 scopus 로고    scopus 로고
    • 47,XXY (Klinefelter Syndrome) and 47,XYY: Estimated rates of and indication for postnatal diagnosis with implications for prenatal counselling
    • DOI 10.1002/(SICI)1097-0223(199704)17:4<363::AID-PD79>3.0.CO;2-O
    • Abramsky L, Chapple J: 47, XXY (Klinefelter syndrome) and 47, XYY: estimated rates of and indication for postnatal diagnosis with implications for prenatal counselling. Prenat Diagn 1997, 17:363-368. (Pubitemid 27192961)
    • (1997) Prenatal Diagnosis , vol.17 , Issue.4 , pp. 363-368
    • Abramsky, L.1    Chapple, J.2
  • 4
    • 0037326103 scopus 로고    scopus 로고
    • Prenatal and postnatal prevalence of Klinefelter syndrome: A national registry study
    • DOI 10.1210/jc.2002-021491
    • Bojesen A, Juul S, Gravholt CH: Prenatal and postnatal prevalence of Klinefelter syndrome: a national registry study. J Clin Endocrinol Metab 2003, 88:622-626. (Pubitemid 36207801)
    • (2003) Journal of Clinical Endocrinology and Metabolism , vol.88 , Issue.2 , pp. 622-626
    • Bojesen, A.1    Juul, S.2    Gravholt, C.H.3
  • 6
    • 84864779894 scopus 로고    scopus 로고
    • Function of the sex chromosomes in mammalian fertility
    • Heard E, Turner J: Function of the sex chromosomes in mammalian fertility. Cold Spring Harb Perspect Biol 2011, 10:a002675.
    • (2011) Cold Spring Harb Perspect Biol , vol.10
    • Heard, E.1    Turner, J.2
  • 9
    • 75349108961 scopus 로고    scopus 로고
    • Neurocognitive outcomes of individuals with a sex chromosome trisomy: XXX, XYY, or XXY: A systematic review
    • Leggett V, Jacobs P, Nation K, Scerif G, Bishop DV: Neurocognitive outcomes of individuals with a sex chromosome trisomy: XXX, XYY, or XXY: a systematic review. Dev Med Child Neurol 2010, 52:119-129.
    • (2010) Dev Med Child Neurol , vol.52 , pp. 119-129
    • Leggett, V.1    Jacobs, P.2    Nation, K.3    Scerif, G.4    Bishop, D.V.5
  • 10
    • 33747489673 scopus 로고    scopus 로고
    • X Chromosomal effects on social cognitive processing and emotion regulation: A study with Klinefelter men (47,XXY)
    • DOI 10.1016/j.schres.2006.02.020, PII S0920996406000867
    • van Rijn S, Swaab H, Aleman A, Kahn RS: X Chromosomal effects on social cognitive processing and emotion regulation: a study with Klinefelter men (47, XXY). Schizophr Res 2006, 84:194-203. (Pubitemid 44255605)
    • (2006) Schizophrenia Research , vol.84 , Issue.2-3 , pp. 194-203
    • Van Rijn, S.1    Swaab, H.2    Aleman, A.3    Kahn, R.S.4
  • 11
    • 73849106322 scopus 로고    scopus 로고
    • The cognitive phenotype in Klinefelter syndrome: A review of the literature including genetic and hormonal factors
    • Boada R, Janusz J, Hutaff-Lee C, Tartaglia N: The cognitive phenotype in Klinefelter syndrome: a review of the literature including genetic and hormonal factors. Dev Disabil Res Rev 2009, 15:284-294.
    • (2009) Dev Disabil Res Rev , vol.15 , pp. 284-294
    • Boada, R.1    Janusz, J.2    Hutaff-Lee, C.3    Tartaglia, N.4
  • 12
    • 53949113560 scopus 로고    scopus 로고
    • Social behavior and autism traits in a sex chromosomal disorder: Klinefelter (47XXY) syndrome
    • van Rijn S, Swaab H, Aleman A, Kahn RS: Social behavior and autism traits in a sex chromosomal disorder: Klinefelter (47XXY) syndrome. J Autism Dev Disord 2008, 38:1634-1641.
    • (2008) J Autism Dev Disord , vol.38 , pp. 1634-1641
    • Van Rijn, S.1    Swaab, H.2    Aleman, A.3    Kahn, R.S.4
  • 13
    • 0038383708 scopus 로고    scopus 로고
    • Executive skills in Klinefelter's syndrome
    • DOI 10.1016/S0028-3932(03)00061-7
    • Temple CM, Sanfilippo PM: Executive skills in Klinefelter's syndrome. Neuropsychologia 2003, 41:1547-1559. (Pubitemid 36808828)
    • (2003) Neuropsychologia , vol.41 , Issue.11 , pp. 1547-1559
    • Temple, C.M.1    Sanfilippo, P.M.2
  • 15
    • 73849109433 scopus 로고    scopus 로고
    • Social function in multiple X and y chromosome disorders: XXY, XYY, XXYY, XXXY
    • Visootsak J, Graham JM Jr: Social function in multiple X and Y chromosome disorders: XXY, XYY, XXYY, XXXY. Dev Disabil Res Rev 2009, 15:328-332.
    • (2009) Dev Disabil Res Rev , vol.15 , pp. 328-332
    • Visootsak, J.1    Graham Jr., J.M.2
  • 17
    • 33646059921 scopus 로고    scopus 로고
    • Morbidity in Klinefelter syndrome: A Danish register study based on hospital discharge diagnoses
    • Bojesen A, Juul S, Birkebaek NH, Gravholt CH: Morbidity in Klinefelter syndrome: a Danish register study based on hospital discharge diagnoses. J Clin Endocrinol Metab 2006, 91:1254-1260.
    • (2006) J Clin Endocrinol Metab , vol.91 , pp. 1254-1260
    • Bojesen, A.1    Juul, S.2    Birkebaek, N.H.3    Gravholt, C.H.4
  • 18
    • 79955524082 scopus 로고    scopus 로고
    • Morbidity and mortality in Klinefelter syndrome (47, XXY)
    • Bojesen A, Gravholt CH: Morbidity and mortality in Klinefelter syndrome (47, XXY). Acta Paediatr 2011, 100:807-813.
    • (2011) Acta Paediatr , vol.100 , pp. 807-813
    • Bojesen, A.1    Gravholt, C.H.2
  • 21
    • 79955472500 scopus 로고    scopus 로고
    • Bone mineral density in Klinefelter syndrome is reduced and primarily determined by muscle strength and resorptive markers, but not directly by testosterone
    • Bojesen A, Birkebaek N, Kristensen K, Heickendorff L, Mosekilde L, Christiansen JS, Gravholt CH: Bone mineral density in Klinefelter syndrome is reduced and primarily determined by muscle strength and resorptive markers, but not directly by testosterone. Osteoporos Int 2011, 22:1441-1450.
    • (2011) Osteoporos Int , vol.22 , pp. 1441-1450
    • Bojesen, A.1    Birkebaek, N.2    Kristensen, K.3    Heickendorff, L.4    Mosekilde, L.5    Christiansen, J.S.6    Gravholt, C.H.7
  • 22
    • 79955506265 scopus 로고    scopus 로고
    • Bone density and risk of osteoporosis in Klinefelter syndrome
    • Ferlin A, Schipilliti M, Foresta C: Bone density and risk of osteoporosis in Klinefelter syndrome. Acta Paediatr 2011, 100:878-884.
    • (2011) Acta Paediatr , vol.100 , pp. 878-884
    • Ferlin, A.1    Schipilliti, M.2    Foresta, C.3
  • 24
    • 65849285253 scopus 로고    scopus 로고
    • Autoimmunity and Klinefelter's syndrome: When men have two X chromosomes
    • Sawalha AH, Harley JB, Scofield RH: Autoimmunity and Klinefelter's syndrome: when men have two X chromosomes. J Autoimmun 2009, 33:31-34.
    • (2009) J Autoimmun , vol.33 , pp. 31-34
    • Sawalha, A.H.1    Harley, J.B.2    Scofield, R.H.3
  • 27
    • 23444442732 scopus 로고    scopus 로고
    • Evaluation of insulin sensitivity in patients with Klinefelter's syndrome: A hyperinsulinemic euglycemic clamp study
    • Yesilova Z, Oktenli C, Sanisoglu SY, Musabak U, Cakir E, Ozata M, Dagalp K: Evaluation of insulin sensitivity in patients with Klinefelter's syndrome: a hyperinsulinemic euglycemic clamp study. Endocr 2005, 27:11-15. (Pubitemid 41112857)
    • (2005) Endocrine , vol.27 , Issue.1 , pp. 11-15
    • Yesilova, Z.1    Oktenli, C.2    Sanisoglu, S.Y.3    Musabak, U.4    Cakir, E.5    Ozata, M.6    Dagalp, K.7
  • 30
    • 77953952014 scopus 로고    scopus 로고
    • Klinefelter's syndrome, type 2 diabetes and the metabolic syndrome: The impact of body composition
    • Bojesen A, Host C, Gravholt CH: Klinefelter's syndrome, type 2 diabetes and the metabolic syndrome: the impact of body composition. Mol Hum Reprod 2010, 16:396-401.
    • (2010) Mol Hum Reprod , vol.16 , pp. 396-401
    • Bojesen, A.1    Host, C.2    Gravholt, C.H.3
  • 31
    • 79955499752 scopus 로고    scopus 로고
    • Insulin resistance and metabolic syndrome in prepubertal boys with Klinefelter syndrome
    • Bardsley MZ, Falkner B, Kowal K, Ross JL: Insulin resistance and metabolic syndrome in prepubertal boys with Klinefelter syndrome. Acta Paediatr 2011, 100:866-870.
    • (2011) Acta Paediatr , vol.100 , pp. 866-870
    • Bardsley, M.Z.1    Falkner, B.2    Kowal, K.3    Ross, J.L.4
  • 32
    • 79955489888 scopus 로고    scopus 로고
    • Body composition, metabolic syndrome and type 2 diabetes in Klinefelter syndrome
    • Gravholt CH, Jensen AS, Host C, Bojesen A: Body composition, metabolic syndrome and type 2 diabetes in Klinefelter syndrome. Acta Paediatr 2011, 100:871-877.
    • (2011) Acta Paediatr , vol.100 , pp. 871-877
    • Gravholt, C.H.1    Jensen, A.S.2    Host, C.3    Bojesen, A.4
  • 33
    • 84867741294 scopus 로고    scopus 로고
    • Prevalence and risk factors of diabetes in patients with Klinefelter syndrome: A longitudinal observational study
    • Jiang-Feng M, Hong-Li X, Xue-Yan W, Min N, Shuang-Yu L, Hong-Ding X, Liang-Ming L: Prevalence and risk factors of diabetes in patients with Klinefelter syndrome: a longitudinal observational study. Fertil Steril 2012, 98:1331-1335.
    • (2012) Fertil Steril , vol.98 , pp. 1331-1335
    • Jiang-Feng, M.1    Hong-Li, X.2    Xue-Yan, W.3    Min, N.4    Shuang-Yu, L.5    Hong-Ding, X.6    Liang-Ming, L.7
  • 34
    • 84874205380 scopus 로고    scopus 로고
    • Positive effects of short course androgen therapy on the neurodevelopmental outcome in boys with 47, XXY syndrome at 36 and 72 months of age
    • Samango-Sprouse CA, Sadeghin T, Mitchell FL, Dixon T, Stapleton E, Kingery M, Gropman AL: Positive effects of short course androgen therapy on the neurodevelopmental outcome in boys with 47, XXY syndrome at 36 and 72 months of age. Am J Med Genet A 2013, 161:501-508.
    • (2013) Am J Med Genet A , vol.161 , pp. 501-508
    • Samango-Sprouse, C.A.1    Sadeghin, T.2    Mitchell, F.L.3    Dixon, T.4    Stapleton, E.5    Kingery, M.6    Gropman, A.L.7
  • 35
    • 79955521590 scopus 로고    scopus 로고
    • Effects of short-course androgen therapy on the neurodevelopmental profile of infants and children with 49, XXXXY syndrome
    • Samango-Sprouse CA, Gropman AL, Sadeghin T, Kingery M, Lutz-Armstrong M, Rogol AD: Effects of short-course androgen therapy on the neurodevelopmental profile of infants and children with 49, XXXXY syndrome. Acta Paediatr 2011, 100:861-865.
    • (2011) Acta Paediatr , vol.100 , pp. 861-865
    • Samango-Sprouse, C.A.1    Gropman, A.L.2    Sadeghin, T.3    Kingery, M.4    Lutz-Armstrong, M.5    Rogol, A.D.6
  • 36
    • 0018150391 scopus 로고
    • Early development of children with sex chromosome aberrations
    • Haka-Ikse K, Stewart DA, Cripps MH: Early development of children with sex chromosome aberrations. Pediatr 1978, 62:761-766. (Pubitemid 9009884)
    • (1978) Pediatrics , vol.62 , Issue.5 , pp. 761-766
    • Haka-Ikse, K.1    Stewart, D.A.2    Cripps, M.H.3
  • 37
    • 0023278302 scopus 로고
    • Gross and fine motor development in 47,XXY and 47,XYY males
    • Salbenblatt JA, Meyers DC, Bender BG, Linden MG, Robinson A: Gross and fine motor development in 47, XXY and 47, XYY males. Pediatr 1987, 80:240-244. (Pubitemid 17119112)
    • (1987) Pediatrics , vol.80 , Issue.2 , pp. 240-244
    • Salbenblatt, J.A.1    Meyers, D.C.2    Bender, B.G.3
  • 38
    • 73849102897 scopus 로고    scopus 로고
    • An extra X or y chromosome: Contrasting the cognitive and motor phenotypes in childhood in boys with 47, XYY syndrome or 47, XXY Klinefelter syndrome
    • Ross JL, Zeger MP, Kushner H, Zinn AR, Roeltgen DP: An extra X or Y chromosome: contrasting the cognitive and motor phenotypes in childhood in boys with 47, XYY syndrome or 47, XXY Klinefelter syndrome. Dev Disabil Res Rev 2009, 15:309-317.
    • (2009) Dev Disabil Res Rev , vol.15 , pp. 309-317
    • Ross, J.L.1    Zeger, M.P.2    Kushner, H.3    Zinn, A.R.4    Roeltgen, D.P.5
  • 42
    • 65549139630 scopus 로고    scopus 로고
    • The organizational-activational hypothesis as the foundation for a unified theory of sexual differentiation of all mammalian tissues
    • Arnold AP: The organizational-activational hypothesis as the foundation for a unified theory of sexual differentiation of all mammalian tissues. Horm Behav 2009, 55:570-578.
    • (2009) Horm Behav , vol.55 , pp. 570-578
    • Arnold, A.P.1
  • 44
    • 0025346057 scopus 로고
    • XY female mice resulting from a heritable mutation in the primary testisdetermining gene, Tdy
    • Lovell-Badge R, Robertson E: XY female mice resulting from a heritable mutation in the primary testis-determining gene, Tdy. Dev 1990, 109:635-646. (Pubitemid 20228658)
    • (1990) Development , vol.109 , Issue.3 , pp. 635-646
    • Lovell-Badge, R.1    Robertson, E.2
  • 47
    • 58049173922 scopus 로고    scopus 로고
    • What does the "four core genotypes" mouse model tell us about sex differences in the brain and other tissues?
    • Arnold AP, Chen X: What does the "four core genotypes" mouse model tell us about sex differences in the brain and other tissues? Front Neuroendocrinol 2009, 30:1-9.
    • (2009) Front Neuroendocrinol , vol.30 , pp. 1-9
    • Arnold, A.P.1    Chen, X.2
  • 48
    • 84874618686 scopus 로고    scopus 로고
    • X and y chromosome complement influence adiposity and metabolism in mice
    • Chen X, McClusky R, Itoh Y, Reue K, Arnold AP: X and Y chromosome complement influence adiposity and metabolism in mice. Endocrinol 2013, 154:1092-1104.
    • (2013) Endocrinol , vol.154 , pp. 1092-1104
    • Chen, X.1    McClusky, R.2    Itoh, Y.3    Reue, K.4    Arnold, A.P.5
  • 49
    • 38849200354 scopus 로고    scopus 로고
    • Sex difference in neural tube defects in p53-null mice is caused by differences in the complement of X not Y genes
    • DOI 10.1002/dneu.20581
    • Chen X, Watkins R, Delot E, Reliene R, Schiestl RH, Burgoyne PS, Arnold AP: Sex difference in neural tube defects in p53-null mice is caused by differences in the complement of X not Y genes. Dev Neurobiol 2008, 68:265-273. (Pubitemid 351199422)
    • (2008) Developmental Neurobiology , vol.68 , Issue.2 , pp. 265-273
    • Chen, X.1    Watkins, R.2    Delot, E.3    Reliene, R.4    Schiestl, R.H.5    Burgoyne, P.S.6    Arnold, A.P.7
  • 52
    • 18544366082 scopus 로고    scopus 로고
    • Chromosomal polymorphism and comparative painting analysis in the zebra finch
    • DOI 10.1007/s10577-005-6602-x
    • Itoh Y, Arnold AP: Chromosomal polymorphism and comparative painting analysis in the zebra finch. Chromosome Res 2005, 13:47-56. (Pubitemid 40655461)
    • (2005) Chromosome Research , vol.13 , Issue.1 , pp. 47-56
    • Itoh, Y.1    Arnold, A.P.2
  • 53
    • 1542470485 scopus 로고    scopus 로고
    • Quantitative magnetic resonance (QMR) method for bone and whole-body-composition analysis
    • DOI 10.1007/s00216-003-2224-3
    • Taicher GZ, Tinsley FC, Reiderman A, Heiman ML: Quantitative magnetic resonance (QMR) method for bone and whole-body-composition analysis. Anal Bioanal Chem 2003, 377:990-1002. (Pubitemid 40877830)
    • (2003) Analytical and Bioanalytical Chemistry , vol.377 , Issue.6 , pp. 990-1002
    • Taicher, G.Z.1    Tinsley, F.C.2    Reiderman, A.3    Heiman, M.L.4
  • 58
    • 23844444214 scopus 로고    scopus 로고
    • XXY mice exhibit gonadal and behavioral phenotypes similar to Klinefelter syndrome
    • DOI 10.1210/en.2005-0278
    • Lue Y, Jentsch JD, Wang C, Rao PN, Hikim AP, Salameh W, Swerdloff RS: XXY mice exhibit gonadal and behavioral phenotypes similar to Klinefelter syndrome. Endocrinol 2005, 146:4148-4154. (Pubitemid 41175787)
    • (2005) Endocrinology , vol.146 , Issue.9 , pp. 4148-4154
    • Lue, Y.1    Jentsch, J.D.2    Wang, C.3    Rao, P.N.4    Sinha Hikim, A.P.5    Salameh, W.6    Swerdloff, R.S.7
  • 60
    • 84856215229 scopus 로고    scopus 로고
    • The end of gonad-centric sex determination in mammals
    • Arnold AP: The end of gonad-centric sex determination in mammals. Trends Genet 2011, 28:55-61.
    • (2011) Trends Genet , vol.28 , pp. 55-61
    • Arnold, A.P.1
  • 61
    • 77951794067 scopus 로고    scopus 로고
    • Global survey of escape from X inactivation by RNA-sequencing in mouse
    • Yang F, Babak T, Shendure J, Disteche CM: Global survey of escape from X inactivation by RNA-sequencing in mouse. Genome Res 2010, 20:614-622.
    • (2010) Genome Res , vol.20 , pp. 614-622
    • Yang, F.1    Babak, T.2    Shendure, J.3    Disteche, C.M.4
  • 62
    • 77949905610 scopus 로고    scopus 로고
    • Transcriptional changes in response to X chromosome dosage in the mouse: Implications for X inactivation and the molecular basis of Turner Syndrome
    • Lopes AM, Burgoyne PS, Ojarikre A, Bauer J, Sargent CA, Amorim A, Affara NA: Transcriptional changes in response to X chromosome dosage in the mouse: implications for X inactivation and the molecular basis of Turner Syndrome. BMC Genomics 2010, 11:82.
    • (2010) BMC Genomics , vol.11 , pp. 82
    • Lopes, A.M.1    Burgoyne, P.S.2    Ojarikre, A.3    Bauer, J.4    Sargent, C.A.5    Amorim, A.6    Affara, N.A.7
  • 63
    • 79955489716 scopus 로고    scopus 로고
    • Expression of selected genes escaping from X inactivation in the 41, XX(Y) mouse model for Klinefelter's syndrome
    • Werler S, Poplinski A, Gromoll J, Wistuba J: Expression of selected genes escaping from X inactivation in the 41, XX(Y) mouse model for Klinefelter's syndrome. Acta Paediatr 2011, 100:885-891.
    • (2011) Acta Paediatr , vol.100 , pp. 885-891
    • Werler, S.1    Poplinski, A.2    Gromoll, J.3    Wistuba, J.4
  • 64
    • 84874189927 scopus 로고    scopus 로고
    • Sexual differentiation in the developing mouse brain: Contributions of sex chromosome genes
    • Wolstenholme JT, Rissman EF, Bekiranov S: Sexual differentiation in the developing mouse brain: contributions of sex chromosome genes. Genes Brain Behav 2012, 12:166-180.
    • (2012) Genes Brain Behav , vol.12 , pp. 166-180
    • Wolstenholme, J.T.1    Rissman, E.F.2    Bekiranov, S.3
  • 65
    • 43749094750 scopus 로고    scopus 로고
    • Sex-specific differences in expression of histone demethylases Utx and Uty in mouse brain and neurons
    • Xu J, Deng X, Watkins R, Disteche CM: Sex-specific differences in expression of histone demethylases Utx and Uty in mouse brain and neurons. J Neurosci 2008, 28:4521-4527.
    • (2008) J Neurosci , vol.28 , pp. 4521-4527
    • Xu, J.1    Deng, X.2    Watkins, R.3    Disteche, C.M.4
  • 66
    • 49749114829 scopus 로고    scopus 로고
    • Sex-specific expression of the X-linked histone demethylase gene Jarid1c in brain
    • Xu J, Deng X, Disteche CM: Sex-specific expression of the X-linked histone demethylase gene Jarid1c in brain. PLoS One 2008, 3:e2553.
    • (2008) PLoS One , vol.3
    • Xu, J.1    Deng, X.2    Disteche, C.M.3
  • 69
    • 15244353967 scopus 로고    scopus 로고
    • X-inactivation profile reveals extensive variability in X-linked gene expression in females
    • DOI 10.1038/nature03479
    • Carrel L, Willard HF: X-inactivation profile reveals extensive variability in X-linked gene expression in females. Nat 2005, 434:400-404. (Pubitemid 40469185)
    • (2005) Nature , vol.434 , Issue.7031 , pp. 400-404
    • Carrel, L.1    Willard, H.F.2
  • 73
    • 77955285002 scopus 로고    scopus 로고
    • Sex-specific parent-of-origin allelic expression in the mouse brain
    • Gregg C, Zhang J, Butler JE, Haig D, Dulac C: Sex-specific parent-of-origin allelic expression in the mouse brain. Sci 2010, 329:682-685.
    • (2010) Sci , vol.329 , pp. 682-685
    • Gregg, C.1    Zhang, J.2    Butler, J.E.3    Haig, D.4    Dulac, C.5
  • 74
    • 84859256941 scopus 로고    scopus 로고
    • Critical evaluation of imprinted gene expression by RNA-Seq: A new perspective
    • DeVeale B, van der Kooy D, Babak T: Critical evaluation of imprinted gene expression by RNA-Seq: a new perspective. PLoS Genet 2012, 8:e1002600.
    • (2012) PLoS Genet , vol.8
    • Deveale, B.1    Van Der-Kooy, D.2    Babak, T.3
  • 75
  • 76
    • 79953043998 scopus 로고    scopus 로고
    • Epigenetic regulation of autosomal gene expression by sex chromosomes
    • Wijchers PJ, Festenstein RJ: Epigenetic regulation of autosomal gene expression by sex chromosomes. Trends Genet 2011, 27:132-140.
    • (2011) Trends Genet , vol.27 , pp. 132-140
    • Wijchers, P.J.1    Festenstein, R.J.2
  • 78
    • 79955521239 scopus 로고    scopus 로고
    • Mouse model for men with klinefelter syndrome: A multifaceted fit for a complex disorder
    • Swerdloff RS, Lue Y, Liu PY, Erkkila K, Wang C: Mouse model for men with klinefelter syndrome: a multifaceted fit for a complex disorder. Acta Paediatr 2011, 100:892-899.
    • (2011) Acta Paediatr , vol.100 , pp. 892-899
    • Swerdloff, R.S.1    Lue, Y.2    Liu, P.Y.3    Erkkila, K.4    Wang, C.5
  • 79
    • 77953931323 scopus 로고    scopus 로고
    • Animal models for Klinefelter's syndrome and their relevance for the clinic
    • Wistuba J: Animal models for Klinefelter's syndrome and their relevance for the clinic. Mol Hum Reprod 2010, 16:375-385.
    • (2010) Mol Hum Reprod , vol.16 , pp. 375-385
    • Wistuba, J.1
  • 83
    • 84859110037 scopus 로고    scopus 로고
    • X-chromosome dosage affects male sexual behavior
    • Bonthuis PJ, Cox KH, Rissman EF: X-chromosome dosage affects male sexual behavior. Horm Behav 2012, 64:565-572.
    • (2012) Horm Behav , vol.64 , pp. 565-572
    • Bonthuis, P.J.1    Cox, K.H.2    Rissman, E.F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.