Effects of sex chromosome aneuploidy on male sexual behavior

Genes, Brain and Behavior

Volumn 7, Issue 6, 2008, Pages 609-617

  Park, J H ^a   Burns Cusato, M ^a   Dominguez Salazar, E ^a   Riggan, A ^a   Shetty, S ^a   Arnold, A P ^b   Rissman, E F ^a  

^a UNIVERSITY OF VIRGINIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Klinefelter syndrome; Libido; Male sex behavior; Sex chromosome aneuploidy

Indexed keywords

TESTOSTERONE;

ANEUPLOIDY; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ARTICLE; AUTOSOME; CASTRATION; CONTROLLED STUDY; EJACULATION; FEMALE; GENE DELETION; GENE FUNCTION; GENE INSERTION; GENOTYPE; KARYOTYPE 46,XX; KARYOTYPE 46,XY; KARYOTYPE 47,XXY; KARYOTYPE 47,XYY; MALE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; SEX CHROMOSOME; SEXUAL BEHAVIOR; SPONTANEOUS MUTATION; SRY GENE; TRANSGENE; X CHROMOSOME; Y CHROMOSOME;

ANEUPLOIDY; ANIMALS; COPULATION; FEMALE; GENOTYPE; MALE; MICE; MICE, TRANSGENIC; ORCHIECTOMY; REACTION TIME; SEX CHROMOSOMES; SEXUAL BEHAVIOR, ANIMAL; TESTOSTERONE; TRANSGENES; X CHROMOSOME; Y CHROMOSOME;

ANIMALIA; MUS;

EID: 48749101251     PISSN: 16011848     EISSN: 1601183X     Source Type: Journal    
DOI: 10.1111/j.1601-183X.2008.00397.x     Document Type: Article

References (39)

1. Boone, K.B., Swerdloff, R.S., Miller, B.L., Geschwind, D.H., Razani, J., Lee, A., Gonzalo, I.G., Haddal, A., Rankin, K., Lu, P. Paul, L 2001) Neuropsychological profiles of adults with Klinefelter syndrome. J Int Neuropsychol Soc 7, 446 456.
2. Brown, W.A., Monti, P.M. Corriveau, D.P 1978) Serum testosterone and sexual activity and interest in men. Arch Sex Behav 7, 97 103.
3. Burgoyne, P.S., Lovell-Badge, R. Rattigan, A 2001) Evidence that the testis determination pathway interacts with a non-dosage compensated, X-linked gene Int J Dev Biol 45, 509 512.
4. Burns-Cusato, M., Scordalakes, E.M. Rissman, E.F 2004) Of mice and missing data: what we know (and need to learn) about male sexual behavior Physiol Behav 83, 217 232.
5. Clemens, L.G., Wee, B.E., Weaver, D.R., Roy, E.J., Goldman, B.D. Rakerd, B 1988) Retention of masculine sexual behavior following castration in male B6D2F1 mice. Physiol Behav 42, 69 76.
6. Corbier, P., Roffi, J. Rhoda, J 1983) Female sexual behavior in male rats: effect of hour of castration at birth. Physiol Behav 30, 613 616.
7. De Vries, G.J., Rissman, E.F., Simerly, R.B., Yang, L.Y., Scordalakes, E.M., Auger, C.J., Swain, A., Lovell-Badge, R., Burgoyne, P.S. Arnold, A.P 2002) A model system for study of sex chromosome effects on sexually dimorphic neural and behavioral traits. J Neurosci 22, 9005 9014.
8. Dominguez-Salazar, E., Bateman, H.L. Rissman, E.F 2004) Background matters: the effects of estrogen receptor alpha gene disruption on male sexual behavior are modified by background strain. Horm Behav 46, 482 490.
9. Gotz, M.J., Johnstone, E.C. Ratcliffe, S.G 1999) Criminality and antisocial behaviour in unselected men with sex chromosome abnormalities. Psychol Med 29, 953 962.
10. Gubbay, J., Vivian, N., Economou, A., Jackson, D., Goodfellow, P. Lovell-Badge, R 1992) Inverted repeat structure of the Sry locus in mice. Proc Natl cad Sci U S A 89, 7953 7957.
11. Kraemer, H.C., Becker, H.B., Brodie, H.K., Doering, C.H., Moos, R.H. Hamburg, D.A 1976) Orgasmic frequency and plasma testosterone levels in normal human males. Arch Sex Behav 5, 125 132.
12. Lanfranco, F., Kamischke, A., Zitzmann, M. Nieschlag, E 2004) Klinefelter's syndrome. Lancet 364, 273 283.
13. Lue, Y., Jentsch, J.D., Wang, C., Rao, P.N., Hikim, A.P., Salameh, W. Swerdloff, R.S 2005) XXY mice exhibit gonadal and behavioral phenotypes similar to Klinefelter syndrome. Endocrinology 146, 4148 4154.
14. McGill, T.E. Blight, W.C 1963) Effects of genotype on the recovery of sex drive in the male mouse. J Comp Physiol Psychol 56, 887 888.
15. McGill, T.E. Tucker, G.R 1964) Genotype and sex drive in intact and in castrated male mice. Science 145, 514 515.
16. Meisel, R.L. Ward, I.L 1981) Fetal female rats are masculinized by male littermates located caudally in the uterus. Science 213, 239 242.
17. Moore, C.L 1992) The role of maternal stimulation in the development of sexual behavior and its neural basis. Ann N Y Acad Sci 662, 160 177.
18. Raboch, J. Starka, L 1973) Reported coital activity of men and levels of plasma testosterone. Arch Sex Behav 2, 309 315.
19. Ratcliffe, S.G., Butler, G.E. Jones, M 1991) Edinburgh study of growth and development of children with sex chromosome abnormalities IV. In Evans, J.A., Hamerton, J.L. Robinson, A. (eds Proceedings of the 5th International Workshop on Sex Chromosome anomalies, March of Dimes Birth Defects Foundation, Birth Defects Original Article Series. Alan R Liss Inc., New York, pp. 1 44.
20. Rives, N., Simeon, N., Milazzo, J.P., Barthelemy, C. Mace, B 2003) Meiotic segregation of sex chromosomes in mosaic and non-mosaic XYY males: case reports and review of the literature. Int J Androl 26, 242 249.
21. Roffi, J., Chami, F., Corbier, P. Edwards, D.A 1987) Testicular hormones during the first few hours after birth augment the tendency of adult male rats to mount receptive females. Physiol Behav 39, 625 628.
22. Scordalakes, E.M. Rissman, E.F 2003) Aggression in male mice lacking functional estrogen receptor alpha. Behav Neurosci 117, 38 45.
23. Shrenker, P. Maxson, S.C 1983) The genetics of hormonal influences on male sexual behavior of mice and rats. Neurosci Biobehav Rev 7, 349 359.
24. Shrenker, P. Maxson, S.C 1984) The DBA/1Bg and DBA/2Bg Y chromosomes compared for their effects on male sexual behaviour. Behav Neural Biol 42, 33 37.
25. Simpson, J.L., de la Cruz, F., Swerdloff, R.S., Samango-Sprouse, C., Skakkebaek, N.E., Graham, J.M., Jr., Hassold, T., Aylstock, M., Meyer-Bahlburg, H.F., Willard, H.F., Hall, J.G., Salameh, W., Boone, K., Staessen, C., Geschwind, D., Giedd, J., Dobs, A.S., Rogol, A., Brinton, B. Paulsen, C.A 2003) Klinefelter syndrome: expanding the phenotype and identifying new research directions. Genet Med 5, 460 468.
26. Sipos, M.L. Nyby, J.G 1998) Intracranial androgenic activation of male-typical behaviours in house mice: concurrent stimulation of the medial preoptic area and medial nucleus of the amygdale. J Neuroendocrinol 10, 577 586.
27. Smyth, C.M. Bremner, W.J 1998) Klinefelter syndrome. Arch Intern Med 158, 1309 1314.
28. Sorensen, K., Nielsen, J., Froland, A. Johnsen, S.G 1979) Psychiatric examination of all eight adult males with the karyotype 46,XX diagnosed in Denmark till 1976. Acta Psychiatr Scand 59, 153 163.
29. Stewart, D.A., Bailey, J.D., Netley, C.T. Park, E 1990) Growth, development, and behavioral outcome from mid-adolescence to adulthood in subjects with chromosome aneuploidy: the Toronto Study. Birth Defects Orig Artic Ser 26, 131 188.
30. Theilgaard, A 1984) A psychological study of the personalities of XYY- and XXY-men. Acta Psychiatr Scand Suppl 315, 1 133.
31. Thomas, T.R. Gerall, A.A 1969) Dissociation of reproductive physiology and behavior induced by neonatal treatment with steroids. Endocrinology 85, 781 784.
32. vom Saal, F.S. Bronson, F.H 1978) In utero proximity of female mouse fetuses to males: effect on reproductive performance during later life. Biol Reprod 19, 842 853.
33. vom Saal, F.S., Grant, W.M., McMullen, C.W. Laves, K.S 1983) High fetal estrogen concentrations: correlation with increased adult sexual activity and decreased aggression in male mice. Science 220, 1306 1309.
34. Walzer, S., Bashir, A.S. Silbert, A.R 1991) Cognitive and behavioral factors in the learning disabilities of 47, XXY and 47, XXY boys. In Evans, J.A., Hamerton, J.L. Robinson, A. (eds Proceedings of the 5th International Workshop on Sex Chromosome anomalies, March of Dimes Birth Defects Foundation, Birth Defects Original Article Series. Alan R Liss Inc., New York, pp. 1 44.
35. Wersinger, S.R. Rissman, E.F 2000) Dopamine activates masculine sexual behavior independent of the estrogen receptor alpha. J Neurosci 20, 4248 4254.
36. Wersinger, S.R., Sannen, K., Villalba, C., Lubahn, D.B., Rissman, E.F. De Vries, G.J 1997) Masculine sexual behavior is disrupted in male and female mice lacking a functional estrogen receptor alpha gene. Horm Behav 32, 176 183.
37. Winter, J.S 1991) Androgen Therapy in Klinefelter Syndrome During Adolescence, Birth Defects: Original Article Series, Wiley-Liss, for the March of Dimes Birth Defects Foundation, New York.
38. Yoshida, A., Miura, K., Nagao, K., Hara, H., Ishii, N. Shirai, M 1997) Sexual function and clinical features of patients with Klinefelter's syndrome with the chief complaint of male infertility. Int J Androl 20, 80 85.
39. Zverina, J., Hampl, R., Sulocava, J. Starka, L 1990) Hormonal status and sexual behaviour of 16 men after surgical castration. Arch Ital Urol Nefrol Androl 62, 55 58.