Bridging population and tissue scale tumor dynamics: A new paradigm for understanding differences in tumor growth and metastatic disease

Cancer Research

Volumn 74, Issue 2, 2014, Pages 426-435

  Gallaher, Jill ^a   Babu, Aravind ^b   Plevritis, Sylvia ^c   Anderson, Alexander R A ^a  

^a H LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE   (United States)

^b Stanford University   (United States)

^c STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BREAST CANCER; BRIDGING POPULATION SCALE MODEL; CANCER SPECIFIC SURVIVAL; CELL FRACTIONATION; CIRCULATING TUMOR CELL; HUMAN; LUNG CANCER; MATHEMATICAL MODEL; METASTASIS; POPULATION MODEL; PRIMARY TUMOR; PRIORITY JOURNAL; TISSUE LEVEL; TISSUE SCALE MODEL; TUMOR GROWTH; TUMOR MODEL; TUMOR VOLUME; VASCULAR TUMOR;

ALGORITHMS; ANOXIA; BREAST NEOPLASMS; CHEMOTAXIS; FEMALE; HUMANS; LUNG NEOPLASMS; MODELS, STATISTICAL; MODELS, THEORETICAL; MONTE CARLO METHOD; NECROSIS; NEOPLASM METASTASIS; NEOPLASTIC CELLS, CIRCULATING; OXYGEN; POPULATION DYNAMICS; SEER PROGRAM; STOCHASTIC PROCESSES; TREATMENT OUTCOME; UNITED STATES; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84892905794     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-13-0759     Document Type: Article

References (56)

1. Gerlee P. The model muddle: in search of tumor growth laws. Cancer Res 2013;73:2407-11.
2. * Stat Database: Incidence-SEER 17 Regs Limited - Use? Hurricane Katrina Impacted Louisiana Cases, Nov. 2007 Sub (1973-2005 varying) - Linked To County Attributes - Total U. S., 1969-2005 Counties, National Cancer Institute, DCCPS, Surveillance Research Program, Cancer Statistics Branch, released April 2008, based on the November 2007 submission.
3. Lin RS, Plevritis SK. Comparing the benefits of screening for breast cancer and lung cancer using a novel natural history model. Cancer Causes Control 2012;23:175-85.
4. Swanson KR, Rockne RC, Claridge J, Chaplain MA, Alvord EC Jr, Anderson AR. Quantifying the role of angiogenesis in malignant progression of gliomas: in silico modeling integrates imaging and histology. Cancer Res 2011;71:7366-75.
5. Hinow P, Gerlee P, McCawley LJ, Quaranta V, Ciobanu M, Wang S, et al. A spatial model of tumor-host interaction: application of chemotherapy. Math Biosci Eng 2009;6:521-46.
6. Dvorak HF. Rous-whipple award lecture: how tumors make bad blood vessels and stroma. Am J Pathol 2003;162:1747-57.
7. Weidner N. New paradigm for vessel intravasation by tumor cells. Am J Pathol 2002;160:1937-9.
8. Hofman V, Bonnetaud C, Ilie MI, Vielh P, Vignaud JM, Flejou JF, et al. Preoperative circulating tumor cell detection using the isolation by size of epithelial tumor cell method for patients with lung cancer is a new prognostic biomarker. Clin Cancer Res 2010;17:827-35.
9. Eschwege P, Moutereau S, Droupy A, Douard R, Gala JL, Benoit G, et al. Prognostic value of prostate circulating cells detection in prostate cancer patients: a prospective study. Br J Cancer 2009;100:608-10.
10. Cristofanilli M, Budd GT, Ellis MJ, Stopeck A, Matera J, Miller MC, et al. Circulating tumor cells, disease progression, and survival in metastatic breast cancer. N Engl J Med 2004;351:781-91.
11. Budd GT, Cristofanilli M, Ellis MJ, Stopeck A, Borden E, Miller MC, et al. Ciculating tumor cells versus imaging-predicting overall survival in metastatic breast cancer. Clin Cancer Res 2006;12:6403-9.
12. Liu MC, Shields PG, Warren RD, Cohen P, Wilkinson M, Ottaviano YL, et al. Circulating tumor cells: a useful predictor of treatment efficacy in metastatic breast cancer. J Clin Oncol 2009;27:5153-9.
13. Nakasu S, Nakasu Y, Fukami T, Jito J, Nozaki K. Growth curve analysis of asymptomatic and symptomatic meningiomas. J Neurooncol 2011;102:303-10.
14. Mayneord WV. On the law of growth of Jensen's rat sarcoma. Cancer Res 1932;16:841-6.
15. Schrek R. A comparison of the growth curves of malignant and normal (embryonic and postembryonic) tissues of the rat. Am J Pathol 1936;12:525-30.
16. Steel GG, Lamerton LF. The growth rate of human tumors. Br J Cancer 1966;20:74-86.
17. Peer PGM, van Dijck JAAM, Hendriks JHCL, Holland R, Verbeek ALM. Age-dependent growth rate of primary breast cancer. Cancer 1993;71:3547-51.
18. Hart D, Shochat E, Agur Z. The growth law of primary breast cancer as inferred from mammography screening trials data. Br J Cancer 1998;78:382-7.
19. Gatenby RA, Frieden BR. Inducing catastrophe in malignant growth. Math Med Biol 2008;25:267-83.
20. Weedon-Fekjaer H, Lindqvist BH, Vatten LJ, Awlen OO, Tretli S. Breast cancer tumor growth estimated through mammography screening data. Breast Cancer Res 2007;10:R41.
21. Laird AK. Dynamics of tumour growth. Br J Cancer 1964;18:490-502.
22. Trivella M, Pezzella F, Pastorino U, Harris AL, Altman DG. Microvessel density as a prognostic factor in non-small-cell lung carcinoma: a meta-analysis of individual patient data. Lancet Oncol online 2007;8:488-99.
23. Dhakal HP, Naume B, Synnestvedt M, Borgen E, Kaaresen R, Schlichting E, et al. Vascularizationinprimary breast carcinomas: its prognostic significance and relationship with tumor cell dissemination. Clin Cancer Res 2008;14:2341-50.
24. Ushijima C, Tsukamoto S, Yamazaki K, Yoshino I, Sugio K, Sugimachi K. High vascularity in the peripheral region of non-small cell lung cancer tissue is associated with tumor progression. Lung Cancer 2001;34:233-41.
25. Dagnon K, Heudes D, Bernaudin JF, Callard P. Computerized morphometric analysis of microvasculature in non-small cell lung carcinoma. Microvasc Res 2008;75:112-8.
26. Offersen BV, Pfeiffer P, Hamilton-Dutoit S, Overgaard J. Patterns of angiogenesis in non-small cell lung carcinoma. Cancer 2001;91:1500-9.
27. Offersen BV, Sørenson FB, Yilmaz M, Knoop A, Overgaard J. Chalkley estimates of angiogenesis in early breast cancer. Acta Oncol 2002;41:695-703.
28. Offersen BV, Borre M, Overgaard J. Quantification of angiogenesis as a prognostic marker in human carcinomas: a critical evaluation of histopathological methods for estimation of vascular density. Eur J Cancer 2003;39:881-90.
29. Takei H, Iino Y, Horiguchi J, Maemura M, Nagaoka H, Koibuchi Y, et al. Highest microvessel count as a long-term prognostic factor in Japanese breast cancer patients. Cancer Lett 2000;156:109-16.
30. Kang YH, Kim KS, Yu YK, Lim SC, Kim YC, Park KO. The relationship between microvessel count and the expression of vascular endothelial growth factor, p53, and K-ras in non-small cell lung cancer. J Korean Med Sci 2001;16:417-23.
31. Kato T, Steers G, Campo L, Roberts H, Leek RD, Turley H, et al. Prognostic significance of microvessel density and other variables in Japanese and British patients with primary invasive breast cancer. Cancer Res UK 2007;97:1277-86.
32. Zhang L, Yankelevitz DF, Henschke CI, Reeves AP, Vazquez MF, Carter D. Variation in vascular distribution in small lung cancers. Lung Cancer 2010;68:389-93.
33. Ng QS, Goh V, Milner J, Sundin J, Wellsted D, Saunders MI, et al. Quantitative helical dynamic contrast enhanced computed tomography assessment of the spatial variation in whole tumour blood volume with radiotherapy in lung cancer. Lung Cancer 2010;69:71-6.
34. Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, et al. Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes. Mol Cell Proteomics 2010;9:1085-99.
35. Vaupel P, Kallinowski F, Okunieff P. Blood flow, oxygen and nutrient supply, and metabolic microenvironment of human tumors: a review. Cancer Res 2006;49:6449-65.
36. Crosse JP, Michiels C. Tumour hypoxia affects the responsiveness of cancer cells to chemotherapy and promotes cancer progression. Anticancer Agents Med Chem 2008;8:790-7.
37. Brown JM, Wilson WR. Exploiting tumor hypoxia in cancer treatment. Nat Rev Cancer 2004;4:437-47.
38. Chaudary N, Hill RP. Hypoxia and metastasis. Clin Cancer Res 2007;13:1947-9.
39. Allan AL, Keeney M. Circulating tumor cell analysis: technical and statistical considerations for the application to the clinic. J Oncol 2009;2010:1-10.
40. Bidard FC, Mathiot C, Delaloge S, Brain E, Giachetti S, de Cremoux P, et al. Single circulating tumor cell detection and overall survival in nonmetastatic breast cancer. Ann Oncol 2010;21:729-33.
41. Cen P, Ni X, Yang J, Graham DY, Li M. Circulating tumor cells in the diagnosis and management of pancreatic cancer. Biochem Biophys Acta 2012;1826:350-6.
42. O'Flaherty JD, Gray S, Richard D, Fennell D, O'Leary JJ, Blackhall FH, et al. Circulating tumour cells, their role in metastasis and their clinical utility in lung cancer. Lung Cancer 2012;76:19-25.
43. Doyden J, Alix-Panabieres C, Hofman P, Parks SK, Chamorey E, Naman H, et al. Circulating tumor cells in prostate cancer: a potential surrogate marker of survival. Crit Rev Oncol Hemotol 2012;81:241-56.
44. Bray D. Cell movements. vol. 467. New York: Garland Publishing; 1992.
45. Pennacchietti S, Michieli P, Galluzzo M, Mazzone M, Giordano S, Comoglio PM. Hypoxia promotes invasive growth by transcriptional activation of the met protooncogene. Cancer Cell 2003;3:347-61.
46. Anderson ARA, Chaplain MAJ. Continuous and discrete mathematical models of tumor-induced angiogenesis. Bull Math Biol 1998;60:857-99.
47. Orme ME, Chaplain MAJ. A mathematical model of vascular tumour growth and invasion. Math Comput Model 1996;23:43-60.
48. Tyson DR, Garbett SP, Frick PL, Quaranta V. Fractional proliferation: a method to deconvolve cell population dynamics from single cell data. Nat Methods Advance Online Publication. 2012;9:923-8.
49. Anderson ARA, Hassanein M, Branch KM, Lu J, Lobdell NA, Maier J, et al. Microenvironmental independence associated with tumor progression. Cancer Res 2009;69:8797-806.
50. Hobson B, Denekamp J. Endothelial proliferation in tumours and normal tissues: continuous labelling studies. Br J Cancer 1984;49:405-13.
51. Ljungkvist ASE, Bussink J, Rijken P, Kaanders JHAM, van de Kogel AJ, Denekamp J. Vascular architecture, hypoxia, and proliferation in firstgeneration xenografts of human head-and-neck squamous cell carcinomas. Int J Radiat Oncol Biol Phys 2002;54:215-28.
52. Lanzen J, Braun RD, Klitzman B, Brizel D, Secomb TW, Dewhirst MW. Direct demonstration of instabilities in oxygen concentrations within the extravascular compartment of an experimental tumor. Cancer Res 2006;66:2219-23.
53. Benjamin LE, Golijanin D, Itin A, Pode D, Keshet E. Selective ablation of immature blood vessels in established human tumors follows vascular endothelial growth factor withdrawal. J Clin Invest 1999;103:159-65.
54. Durand RE, Sham E. The lifetime of hypoxic human tumor cells. Int J Radiat Oncol Biol Phys 1998;42:711-5.
55. Ljungkvist ASE, Bussink J, Kaanders JHAM, Rijken PFJW, Begg AC, Raleigh JA, et al. Hypoxic cell turnover in different solid tumor lines. Int J Radiat Oncol Biol Phys 2005;62:1157-68.
56. Vaupel P. Metabolic microenvironment of tumor cells: a key factor in malignant progression. Exp Oncol 2010;32:125-7.