-
1
-
-
0035225541
-
Nitrogen-Containing Metabolites from Marine Cyanobacteria
-
Gerwick, W.H.; Tan, L.T.; Sitachitta, N. Nitrogen-Containing Metabolites from Marine Cyanobacteria. Alkaloids Chem. Biol. 2001, 57, 75-184.
-
(2001)
Alkaloids Chem. Biol.
, vol.57
, pp. 75-184
-
-
Gerwick, W.H.1
Tan, L.T.2
Sitachitta, N.3
-
2
-
-
33947104489
-
Bioactive natural products from marine cyanobacteria for drug discovery
-
Tan, L.T. Bioactive natural products from marine cyanobacteria for drug discovery. Phytochemistry 2007, 68, 954-979.
-
(2007)
Phytochemistry
, vol.68
, pp. 954-979
-
-
Tan, L.T.1
-
3
-
-
84861161752
-
Marine cyanobacteria: A treasure trove of bioactive secondary metabolites for drug discovery
-
Tan, L.T. Marine cyanobacteria: A treasure trove of bioactive secondary metabolites for drug discovery. Stud. Nat. Prod. Chem. 2012, 36, 67-110.
-
(2012)
Stud. Nat. Prod. Chem.
, vol.36
, pp. 67-110
-
-
Tan, L.T.1
-
4
-
-
84883215375
-
Pharmaceutical agents from filamentous marine cyanobacteria
-
Tan, L.T. Pharmaceutical agents from filamentous marine cyanobacteria. Drug Discov. Today 2013, 18, 863-871.
-
(2013)
Drug Discov. Today
, vol.18
, pp. 863-871
-
-
Tan, L.T.1
-
5
-
-
84880800709
-
State of knowledge and concerns on cyanobacterial blooms and cyanotoxins
-
Merel, S.; Walker, D.; Chicana, R.; Snyder, S.; Baures, E.; Thomas, O. State of knowledge and concerns on cyanobacterial blooms and cyanotoxins. Environ. Int. 2013, 59, 303-327.
-
(2013)
Environ. Int.
, vol.59
, pp. 303-327
-
-
Merel, S.1
Walker, D.2
Chicana, R.3
Snyder, S.4
Baures, E.5
Thomas, O.6
-
6
-
-
33845471434
-
Absolute stereochemistries of the aplysiatoxins and oscillatoxin A
-
Moore, R.E.; Blackman, A.J.; Cheuk, C.E.; Mynderse, J.S.; Mataumoto, G.K.; Clardy, J.; Woodard, R.W.; Craig, J.C. Absolute stereochemistries of the aplysiatoxins and oscillatoxin A. J. Org. Chem. 1984, 49, 2484-2489.
-
(1984)
J. Org. Chem.
, vol.49
, pp. 2484-2489
-
-
Moore, R.E.1
Blackman, A.J.2
Cheuk, C.E.3
Mynderse, J.S.4
Mataumoto, G.K.5
Clardy, J.6
Woodard, R.W.7
Craig, J.C.8
-
7
-
-
77951569334
-
Nhatrangins A and B, aplysiatoxin-related metabolites from the marine cyanobacterium Lyngbya majuscula from Vietnam
-
Chlipala, G.E.; Pham, H.T.; Nguyen, V.H.; Krunic, A.; Shim, S.H.; Soejarto, D.D.; Orjala, J. Nhatrangins A and B, aplysiatoxin-related metabolites from the marine cyanobacterium Lyngbya majuscula from Vietnam. J. Nat. Prod. 2010, 73, 784-787.
-
(2010)
J. Nat. Prod.
, vol.73
, pp. 784-787
-
-
Chlipala, G.E.1
Pham, H.T.2
Nguyen, V.H.3
Krunic, A.4
Shim, S.H.5
Soejarto, D.D.6
Orjala, J.7
-
8
-
-
33846457375
-
Toxins of cyanobacteria
-
Van Apeldoorn, M.E.; van Egmond, H.P.; Speijers, G.J.A.; Bakker, G.J.I. Toxins of cyanobacteria. Mol. Nutr. Food Res. 2007, 51, 7-60.
-
(2007)
Mol. Nutr. Food Res.
, vol.51
, pp. 7-60
-
-
Van Apeldoorn, M.E.1
Van Egmond, H.P.2
Speijers, G.J.A.3
Bakker, G.J.I.4
-
9
-
-
0037303088
-
Discovery and prospect of protein kinase C research: Epilogue
-
Nishizuka, Y. Discovery and prospect of protein kinase C research: Epilogue. J. Biochem. 2003, 133, 155-158.
-
(2003)
J. Biochem.
, vol.133
, pp. 155-158
-
-
Nishizuka, Y.1
-
10
-
-
0034280331
-
Protein kinase C as a drug target: Implications for drug or diet prevention and treatment of cancer
-
Carter, C.A. Protein kinase C as a drug target: Implications for drug or diet prevention and treatment of cancer. Curr. Drug Targets 2000, 1, 163-183.
-
(2000)
Curr. Drug Targets
, vol.1
, pp. 163-183
-
-
Carter, C.A.1
-
11
-
-
67650558672
-
A simple analogue of tumor-promoting aplysiatoxin is an antineoplastic agent rather than a tumor promoter: Development of a synthetically accessible protein kinase C activator with bryostatin-like activity
-
Nakagawa, Y.; Yanagita, R.C.; Hamada, N.; Murakami, A.; Takahashi, H.; Saito, N.; Irie, K. A simple analogue of tumor-promoting aplysiatoxin is an antineoplastic agent rather than a tumor promoter: Development of a synthetically accessible protein kinase C activator with bryostatin-like activity. J. Am. Chem. Soc. 2009, 131, 7573-7579.
-
(2009)
J. Am. Chem. Soc.
, vol.131
, pp. 7573-7579
-
-
Nakagawa, Y.1
Yanagita, R.C.2
Hamada, N.3
Murakami, A.4
Takahashi, H.5
Saito, N.6
Irie, K.7
-
12
-
-
77956937206
-
Role of the phenolic hydroxyl group in the biological activities of simplified analogue of aplysiatoxin with antiproliferative activity
-
Yanagita, R.C.; Kamachi, H.; Tanaka, K.; Murakami, A.; Nakagawa, Y.; Tokuda, H.; Nagai, H.; Irie, K. Role of the phenolic hydroxyl group in the biological activities of simplified analogue of aplysiatoxin with antiproliferative activity. Bioorg. Med. Chem. Lett. 2010, 20, 6064-6066.
-
(2010)
Bioorg. Med. Chem. Lett.
, vol.20
, pp. 6064-6066
-
-
Yanagita, R.C.1
Kamachi, H.2
Tanaka, K.3
Murakami, A.4
Nakagawa, Y.5
Tokuda, H.6
Nagai, H.7
Irie, K.8
-
13
-
-
79959534894
-
Synthesis and biological evaluation of the 12,12-dimethyl derivative of Aplog-1, an anti-proliferative analog of tumor-promoting aplysiatoxin
-
Nakagawa, Y.; Kikumori, M.; Yanagita, R.C.; Murakami, A.; Tokuda, H.; Nagai, H.; Irie, K. Synthesis and biological evaluation of the 12,12-dimethyl derivative of Aplog-1, an anti-proliferative analog of tumor-promoting aplysiatoxin. Biosci. Biotechnol. Biochem. 2011, 75, 1167-1173.
-
(2011)
Biosci. Biotechnol. Biochem.
, vol.75
, pp. 1167-1173
-
-
Nakagawa, Y.1
Kikumori, M.2
Yanagita, R.C.3
Murakami, A.4
Tokuda, H.5
Nagai, H.6
Irie, K.7
-
14
-
-
84862275351
-
Structure-activity studies on the spiroketal moiety of a simplified analogue of debromoaplysiatoxin with antiproliferative activity
-
Kikumori, M.; Yanagita, R.C.; Tokuda, H.; Suzuki, N.; Nagai, H.; Suenaga, K.; Irie, K. Structure-activity studies on the spiroketal moiety of a simplified analogue of debromoaplysiatoxin with antiproliferative activity. J. Med. Chem. 2012, 55, 5614-5626.
-
(2012)
J. Med. Chem.
, vol.55
, pp. 5614-5626
-
-
Kikumori, M.1
Yanagita, R.C.2
Tokuda, H.3
Suzuki, N.4
Nagai, H.5
Suenaga, K.6
Irie, K.7
-
15
-
-
84860338528
-
Challenges to the development of bryostatin-type anticancer drugs based on the activation mechanism of protein kinase Cδ
-
Irie, K.; Yanagita, R.C.; Nakagawa, Y. Challenges to the development of bryostatin-type anticancer drugs based on the activation mechanism of protein kinase Cδ. Med. Res. Rev. 2012, 32, 518-535.
-
(2012)
Med. Res. Rev.
, vol.32
, pp. 518-535
-
-
Irie, K.1
Yanagita, R.C.2
Nakagawa, Y.3
-
16
-
-
84864182351
-
Artificial analogs of naturally occurring tumor promotors as biochemical tools and therapeutic leads
-
Nakagawa, Y. Artificial analogs of naturally occurring tumor promotors as biochemical tools and therapeutic leads. Biosci. Biotechnol. Biochem. 2012, 76, 1262-1274.
-
(2012)
Biosci. Biotechnol. Biochem.
, vol.76
, pp. 1262-1274
-
-
Nakagawa, Y.1
-
17
-
-
84876668291
-
Structure-activity studies on the side chain of a simplified analog of aplysiatoxin (aplog-1) with anti-proliferative activity
-
Kamachi, H.; Tanaka, K.; Yanagita, R.C.; Murakami, A.; Murakami, K.; Tokuda, H.; Suzuki, N.; Nakagawa, Y.; Irie, K. Structure-activity studies on the side chain of a simplified analog of aplysiatoxin (aplog-1) with anti-proliferative activity. Bioorg. Med. Chem. 2013, 21, 2695-2702.
-
(2013)
Bioorg. Med. Chem.
, vol.21
, pp. 2695-2702
-
-
Kamachi, H.1
Tanaka, K.2
Yanagita, R.C.3
Murakami, A.4
Murakami, K.5
Tokuda, H.6
Suzuki, N.7
Nakagawa, Y.8
Irie, K.9
-
18
-
-
84879689027
-
Effects of the methoxy group in the side chain of debromoaplysiatoxin on its tumor-promoting and anti-proliferative activities
-
Yanagita, R.C.; Kamachi, H.; Kikumori, M.; Tokuda, H.; Suzuki, N.; Suenaga, K.; Nagai, H.; Irie, K. Effects of the methoxy group in the side chain of debromoaplysiatoxin on its tumor-promoting and anti-proliferative activities. Bioorg. Med. Chem. Lett. 2013, 23, 4319-4323.
-
(2013)
Bioorg. Med. Chem. Lett.
, vol.23
, pp. 4319-4323
-
-
Yanagita, R.C.1
Kamachi, H.2
Kikumori, M.3
Tokuda, H.4
Suzuki, N.5
Suenaga, K.6
Nagai, H.7
Irie, K.8
-
19
-
-
84880918683
-
Structure-activity studies at position 27 of aplog-1, a simplified analog of debromoaplysiatoxin with anti-proliferative activity
-
Hanaki, Y.; Kikumori, M.; Ueno, S.; Tokuda, H.; Suzuki, N.; Irie, K. Structure-activity studies at position 27 of aplog-1, a simplified analog of debromoaplysiatoxin with anti-proliferative activity. Tetrahedron 2013, 69, 7636-7645.
-
(2013)
Tetrahedron
, vol.69
, pp. 7636-7645
-
-
Hanaki, Y.1
Kikumori, M.2
Ueno, S.3
Tokuda, H.4
Suzuki, N.5
Irie, K.6
-
20
-
-
34347342849
-
Characterization of reemerging Chikungunya virus
-
Sourisseau, M.; Schilte, C.; Casartelli, N.; Trouillet, C.; Guivel-Benhassine, F.; Rudnicka, D.; Sol-Foulon, N.; Le Roux, K.; Prevost, M.C.; Fsihi, H.; et al. Characterization of reemerging Chikungunya virus. PLoS Pathog. 2007, 3, e89.
-
(2007)
PLoS Pathog.
, vol.3
-
-
Sourisseau, M.1
Schilte, C.2
Casartelli, N.3
Trouillet, C.4
Guivel-Benhassine, F.5
Rudnicka, D.6
Sol-Foulon, N.7
Le Roux, K.8
Prevost, M.C.9
Fsihi, H.10
-
21
-
-
77949538318
-
Re-emergence of Chikungunya virus in South-east Asia: Virological evidence from Sri Lanka and Singapore
-
Hapuarachchi, H.C.; Bandara, K.B.; Sumanadasa, S.D.; Hapugoda, M.D.; Lai, Y.L.; Lee, K.S.; Tan, L.K.; Lin, R.T.; Ng, L.F.; Bucht, G.; et al. Re-emergence of Chikungunya virus in South-east Asia: Virological evidence from Sri Lanka and Singapore. J. Gen. Virol. 2010, 91, 1067-1076.
-
(2010)
J. Gen. Virol.
, vol.91
, pp. 1067-1076
-
-
Hapuarachchi, H.C.1
Bandara, K.B.2
Sumanadasa, S.D.3
Hapugoda, M.D.4
Lai, Y.L.5
Lee, K.S.6
Tan, L.K.7
Lin, R.T.8
Ng, L.F.9
Bucht, G.10
-
22
-
-
84859169887
-
Chikungunya disease: Infection-associated markers from the acute to the chronic phase of arbovirus-induced arthralgia
-
Dupuis-Maguiraga, L.; Noret, M.; Brun, S.; Le Grand, R.; Gras, G.; Roques, P. Chikungunya disease: Infection-associated markers from the acute to the chronic phase of arbovirus-induced arthralgia. PLoS Negl. Trop. Dis. 2012, 6, e1446.
-
(2012)
PLoS Negl. Trop. Dis.
, vol.6
-
-
Dupuis-Maguiraga, L.1
Noret, M.2
Brun, S.3
Le Grand, R.4
Gras, G.5
Roques, P.6
-
23
-
-
77949752839
-
Chikungunya disease in nonhuman primates involves long-term viral persistence in macrophages
-
Labadie, K.; Larcher, T.; Joubert, C.; Mannioui, A.; Delache, B.; Brochard, P.; Guigand, L.; Dubreil, L.; Lebon, P.; Verrier, B.; et al. Chikungunya disease in nonhuman primates involves long-term viral persistence in macrophages. J. Clin. Invest. 2010, 120, 894-906.
-
(2010)
J. Clin. Invest.
, vol.120
, pp. 894-906
-
-
Labadie, K.1
Larcher, T.2
Joubert, C.3
Mannioui, A.4
Delache, B.5
Brochard, P.6
Guigand, L.7
Dubreil, L.8
Lebon, P.9
Verrier, B.10
-
24
-
-
0023159188
-
Aedes albopictus in North America: Probable introduction in used tires from northern Asia
-
Hawley, W.A.; Reiter, P.; Copeland, R.S.; Pumpuni, C.B.; Craig, G.B., Jr. Aedes albopictus in North America: Probable introduction in used tires from northern Asia. Science 1987, 236, 1114-1116.
-
(1987)
Science
, vol.236
, pp. 1114-1116
-
-
Hawley, W.A.1
Reiter, P.2
Copeland, R.S.3
Pumpuni, C.B.4
Craig Jr., G.B.5
-
25
-
-
84884591270
-
Chikungunya virus: An update on antiviral development and challenges
-
Kaur, P.; Chu, J.J. Chikungunya virus: An update on antiviral development and challenges. Drug Discov. Today 2013, 18, 969-983.
-
(2013)
Drug Discov. Today
, vol.18
, pp. 969-983
-
-
Kaur, P.1
Chu, J.J.2
-
26
-
-
0018241278
-
The use of Artemia nauplii for toxicity tests - A critical anaysis
-
Sorgeloos, P.; Remiche-Van Der Wielen, C.; Persoone, G. The use of Artemia nauplii for toxicity tests - A critical anaysis. Ecotoxicol. Environ. Saf. 1978, 2, 249-255.
-
(1978)
Ecotoxicol. Environ. Saf.
, vol.2
, pp. 249-255
-
-
Sorgeloos, P.1
Remiche-Van Der Wielen, C.2
Persoone, G.3
|