Gender differences in orthostatic tolerance in the elderly

Aging Clinical and Experimental Research

Volumn 25, Issue 6, 2013, Pages 659-665

  Mellingsæter, Marte Rognstad ^a,b   Wyller, Vegard Bruun ^b,c   Wyller, Torgeir Bruun ^a,b   Ranhoff, Anette Hylen ^d,e  

^a OSLO UNIVERSITY HOSPITAL   (Norway)

^b UNIVERSITY OF OSLO   (Norway)

^c AKERSHUS UNIVERSITY HOSPITAL   (Norway)

^d UNIVERSITY OF BERGEN   (Norway)

^e DIAKONHJEMMET HOSPITAL   (Norway)

Author keywords

Elderly; Gender; Orthostatic tolerance; Syncope

Indexed keywords

AGED; ARTICLE; AUTONOMIC NERVOUS SYSTEM FUNCTION; BLOOD PRESSURE; BLOOD PRESSURE VARIABILITY; BODY MASS; BODY SURFACE; CONSCIOUSNESS DISORDER; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; FAINTNESS; FEMALE; GERIATRIC CARE; HEAD TILTING; HEART INDEX; HEART OUTPUT; HEART RATE; HEART RATE VARIABILITY; HEART STROKE VOLUME; HUMAN; HUMAN EXPERIMENT; KNEE PAIN; MALAISE; MALE; MEAN ARTERIAL PRESSURE; NAUSEA; NORMAL HUMAN; ORTHOSTATIC TOLERANCE; PALLOR; PARASYMPATHETIC TONE; PRESSORECEPTOR; PRESYNCOPE; REST; SEX DIFFERENCE; SWEATING; SYSTOLIC BLOOD PRESSURE; VASCULAR RESISTANCE; VERY ELDERLY; VISUAL DISORDER;

AGED; AGED, 80 AND OVER; BLOOD PRESSURE; DIZZINESS; FEMALE; HEART RATE; HUMANS; MALE; POSTURE; PRESSORECEPTORS; SEX FACTORS; STROKE VOLUME; SYNCOPE; TILT-TABLE TEST; VASCULAR RESISTANCE;

EID: 84892867732     PISSN: 15940667     EISSN: 17208319     Source Type: Journal    
DOI: 10.1007/s40520-013-0092-z     Document Type: Article

References (34)

1. Ferrer A, Formiga F, Plana-Ripoll O, Tobella M.A., Gil A., Pujol R. (2012) Risk of falls in 85-year-olds is associated with functional and cognitive status: the Octabaix Study. Arch Gerontol Geriatr 54:352-356
2. Lehtola S, Koistinen P, Luukinen H. (2006) Falls and injurious falls late in home-dwelling life. Arch Gerontol Geriatr 42:217-224
3. Wofford JL, Heuser MD, Moran W.P., Schwartz E., Mittelmark M.B. (1994) Community surveillance of falls among the elderly using computerized EMS transport data. Am J Emerg Med 12:433-437
4. Lofthus CM, Osnes EK, Falch J.A., Kaastad TS, Kristiansen IS, Nordsletten L, Stensvold I., Meyer H.E. (2001) Epidemiology of hip fractures in Oslo, Norway. Bone 29:413-418
5. Tinetti ME, Speechley M, Ginter S.F. (1988) Risk factors for falls among elderly persons living in the community. N Engl J Med 319:1701-1707
6. Moya A, Sutton R, Ammirati F., Blanc JJ, Brignole M, Dahm JB, Deharo J.C., Gajek J., Gjesdal K, Krahn A, Massin M, Pepi M, Pezawas T, Ruiz GR, Sarasin F, Ungar A, van Dijk JG, Walma EP, Wieling W (2009) Guidelines for the diagnosis and management of syncope (version 2009). Eur Heart J 30:2631-2671
7. Brignole M (2006) Distinguishing syncopal from non-syncopal causes of fall in older people. Age Ageing 35(Suppl 2):ii46-ii50
8. Ungar A, Mussi C, Del R.A., Noro G., Abete P, Ghirelli L, Cellai T., Landi A, Salvioli G, Rengo F, Marchionni N, Masotti G (2006) Diagnosis and characteristics of syncope in older patients referred to geriatric departments. J Am Geriatr Soc 54:1531-1536
9. Jonsson PV, Lipsitz LA, Kelley M, Koestner J. (1990) Hypotensive responses to common daily activities in institutionalized elderly. A potential risk for recurrent falls. Arch Intern Med 150:1518-1524
10. Shaw FE, Kenny R.A. (1997) The overlap between syncope and falls in the elderly. Postgrad Med J 73:635-639
11. Grenon SM, Xiao X, Hurwitz S., Sheynberg N, Kim C, Seely E.W., Cohen RJ, Williams GH (2006) Why is orthostatic tolerance lower in women than in men? Renal and cardiovascular responses to simulated microgravity and the role of midodrine. J Investig Med 54:180-190
12. Convertino VA (1998) Gender differences in autonomic functions associated with blood pressure regulation. Am J Physiol 275:R1909-R1920
13. Franke WD, Johnson CP, Steinkamp J.A., Wang R., Halliwill J.R. (2003) Cardiovascular and autonomic responses to lower body negative pressure: do not explain gender differences in orthostatic tolerance. Clin Auton Res 13:36-44
14. Laitinen T, Niskanen L, Geelen G., Lansimies E, Hartikainen J. (2004) Age dependency of cardiovascular autonomic responses to head-up tilt in healthy subjects. J Appl Physiol 96:2333-2340
15. Barnett SR, Morin RJ, Kiely D.K., Gagnon M., Azhar G, Knight EL, Nelson J.C., Lipsitz L.A. (1999) Effects of age and gender on autonomic control of blood pressure dynamics. Hypertension 33:1195-1200
16. Romero-Ortuno R., Cogan L, Foran T., Fan CW, Kenny R.A. (2010) Using the Finometer to examine sex differences in hemodynamic responses to orthostasis in older people. Blood Press Monit. 15:8-17
17. Barantke M, Krauss T, Ortak J., Lieb W, Reppel M, Burgdorf C., Pramstaller PP, Schunkert H, Bonnemeier H (2008) Effects of gender and aging on differential autonomic responses to orthostatic maneuvers. J Cardiovasc Electrophysiol 19:1296-1303
18. Fortin J, Habenbacher W, Heller A., Hacker A, Grullenberger R, Innerhofer J., Passath H, Wagner C, Haitchi G, Flotzinger D, Pacher R, Wach P (2006) Non-invasive beat-to-beat cardiac output monitoring by an improved method of transthoracic bioimpedance measurement. Comput Biol Med 36:1185-1203
19. Imholz BP, Wieling W, van Montfrans GA, Wesseling K.H. (1998) Fifteen years experience with finger arterial pressure monitoring: assessment of the technology. Cardiovasc Res 38:605-616
20. Malik et al (1996) Heart rate variability: standards of measurement, physiological interpretation and clinical use. Task Force of the European Society of Cardiology and the North American Society of Pacing and Electrophysiology. Circulation 93:1043-1065
21. Bertinieri G, di Rienzo M, Cavallazzi A, Ferrari A.U., Pedotti A., Mancia G. (1985) A new approach to analysis of the arterial baroreflex. J Hypertens 3(Suppl 3):S79-S81
22. Parry SW, Reeve P, Lawson J., Shaw FE, Davison J, Norton M, Frearson R., Kerr S, Newton JL (2009) The Newcastle protocols 2008: an update on head-up tilt table testing and the management of vasovagal syncope and related disorders. Heart 95:416-420
23. Galizia G, Abete P, Mussi C., Noro G, Morrione A, Langellotto A., Landi A, Cacciatore F, Masotti G, Rengo F, Marchionni N, Ungar A (2008) Role of early symptoms in assessment of syncope in elderly people: results from the Italian Group for the Study of Syncope in the Elderly. J Am Geriatr Soc 57:18-23
24. Brignole M, Menozzi C, Del R.A., Costa S., Gaggioli G, Bottoni N, Bartoli P., Sutton R. (2000) New classification of haemodynamics of vasovagal syncope: beyond the VASIS classification. Analysis of the pre-syncopal phase of the tilt test without and with nitroglycerin challenge. Vasovagal Syncope International Study. Europace. 2:66-76
25. Levy MN, Pappano A.J. (2007) Cardiovascular physiology, 9th edn. Mosby Elsevier, Amsterdam
26. Parry SW, Norton M, Pairman J., Baptist M, Wilton K, Reeve P., Sutcliffe K, Newton JL (2009) Impedance cardiography: a role in vasovagal syncope diagnosis? Age Ageing 38:718-723
27. Monahan KD, Ray C.A. (2004) Gender affects calf venous compliance at rest and during baroreceptor unloading in humans. Am J Physiol Heart Circ Physiol 286:H895-H901
28. Lindenberger M, Lanne T. (2007) Decreased capillary filtration but maintained venous compliance in the lower limb of aging women. Am J Physiol Heart Circ Physiol 293:H3568-H3574
29. Tomiyama H, Yamashina A, Arai T., Hirose K, Koji Y, Chikamori T., Hori S, Yamamoto Y, Doba N, Hinohara S (2003) Influences of age and gender on results of noninvasive brachialankle pulse wave velocity measurement-a survey of 12517 subjects. Atherosclerosis 166:303-309
30. Smith JJ, Porth C.J. (1991) Posture and the circulation: the age effect. Exp Gerontol 26:141-162
31. Ludwig DA, Vernikos J, Wade C.E., Convertino V.A. (2001) Blood pressure changes during orthostatic stress: evidence of gender differences in neuroeffector distribution. Aviat Space Environ Med 72:892-898
32. Groothuis JT, Thijssen DH, Kooijman M, Paulus R., Hopman M.T. (2008) Attenuated peripheral vasoconstriction during an ortho-static challenge in older men. Age Ageing 37:680-684
33. Gelman S (2008) Venous function and central venous pressure: a physiologic story. Anesthesiology 108:735-748
34. Shibao C, Grijalva CG, Raj S.R., Biaggioni I., Griffin M.R. (2007) Orthostatic hypotension-related hospitalizations in the United States. Am J Med 120:975-980