Rhesus macaque rectal and duodenal tissues exhibit B-cell sub-populations distinct from peripheral blood that continuously secrete antigen-specific IgA in short-term explant cultures

Vaccine

Volumn 32, Issue 7, 2014, Pages 872-880

  Thomas, Michael A ^a   Demberg, Thorsten ^a   Vargas Inchaustegui, Diego A ^a   Xiao, Peng ^a   Tuero, Iskra ^a   Venzon, David ^a   Weiss, Deborah ^b   Treece, James ^b   Robert Guroff, Marjorie ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b ADVANCED BIOSCIENCE LABORATORIES INC   (United States)

Author keywords

AIDS vaccine; IgA; Memory B cells; Mucosal explant cultures; SIV SHIV infected rhesus macaques

Indexed keywords

IMMUNOGLOBULIN A ANTIBODY; IMMUNOGLOBULIN D; IMMUNOGLOBULIN G;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBODY ISOLATION; ANTIGEN SPECIFICITY; ARTICLE; CONTROLLED STUDY; DUODENUM BIOPSY; EXPLANT; FLOW CYTOMETRY; HUMAN IMMUNODEFICIENCY VIRUS; MEMORY CELL; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PLASMA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECTUM BIOPSY; RHESUS MONKEY; SECRETORY CELL; SIMIAN IMMUNODEFICIENCY VIRUS; SUPERNATANT; T LYMPHOCYTE SUBPOPULATION; VIRUS LOAD;

AIDS VACCINE; IGA; MEMORY B-CELLS; MUCOSAL EXPLANT CULTURES; SIV/SHIV INFECTED RHESUS MACAQUES;

ANIMALS; ANTIGENS, CD27; BIOPSY; DUODENUM; IMMUNOGLOBULIN A; IMMUNOLOGIC MEMORY; MACACA MULATTA; PLASMA CELLS; RECTUM; SIMIAN ACQUIRED IMMUNODEFICIENCY SYNDROME; SIMIAN IMMUNODEFICIENCY VIRUS;

EID: 84892840924     PISSN: 0264410X     EISSN: 18732518     Source Type: Journal    
DOI: 10.1016/j.vaccine.2013.12.014     Document Type: Article

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