Lamina propria plasma cells in inflammatory bowel disease: Intracellular detection of immunoglobulins using flow cytometry

Immunobiology

Volumn 206, Issue 5, 2002, Pages 546-557

  Dorn, Isabel ^a   Schlenke, Peter ^a   Mascher, Beate ^a   Stange, Eduard Friedrich ^a   Seyfarth, Michael ^a  

^a UNIVERSITY OF LÜBECK   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; AZATHIOPRINE; CD38 ANTIGEN; CORTISONE; IMMUNOGLOBULIN; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2; IMMUNOGLOBULIN G3; IMMUNOGLOBULIN G4; IMMUNOGLOBULIN M; MESALAZINE; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER;

ADULT; ANTIGEN DETECTION; CELL PERMEABILIZATION; CLINICAL ARTICLE; CONTROLLED STUDY; CROHN DISEASE; ENTERITIS; FEMALE; FLOW CYTOMETRY; GASTROINTESTINAL MUCOSA; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LYMPHOCYTE SUBPOPULATION; MALE; MICROSCOPY; OBSERVER VARIATION; PLASMA CELL; PRIORITY JOURNAL; REPRODUCIBILITY; REVIEW; SCORING SYSTEM; ULCERATIVE COLITIS;

EID: 0036993384     PISSN: 01712985     EISSN: None     Source Type: Journal    
DOI: 10.1078/0171-2985-00203     Document Type: Review

References (25)

1. BRANDTZAEG P., K. BAKLIEN, O. FAUSA, and P. S. HOTEL. 1974. Immunohistochemical characterization of local immunoglobulin formation in ulcerative colitis. Gastroenterology 66: 1123-1136.
2. BAKLIEN K., and P. BRANDTZAEG. 1975. Comparative mapping of the local distribution of immunoglobulin-containing cells in ulcerative colitis and Crohn's disease of the colon. Clin. Exp. Immunol. 22: 197-209.
3. ROSEKRANS P. C. M., C. J. L. M. MEIJER A. M. VAN DER WAL, C. J. CORNELISSE, and J. LINDEMANN. 1980. Immunoglobulin containing cells in inflammatory bowel disease of the colon: a morphometric and immunohistochemical study. Gut 21: 941-947.
4. BAKLIEN K., and P. BRANDTZAEG. 1976. Immunohistochemical characterization of local immunoglobulin formation in Crohn's disease of the ileum. Scand. J. Gastroent. 11: 447-457.
5. SCOTT M. G., M. H. NAHM, K. MACKE, G. S. NASH, M. J. BERTOVICH, and R. P. MACDERMOTT. 1986. Spontaneous secretion of IgG subclasses by intestinal mononuclear cells: Differences between ulcerative colitis, Crohn's disease, and controls. Clin. Exp. Immunol. 66: 209-215.
6. RÜTHLEIN J., M. IBE, W. BURGHARDT, J. MÖSSNER, and I. O. AUER. 1992. Immunoglobulin G (IgG), IgG1 and IgG2 determinations from endoscopic biopsy specimen in control, Crohn's disease, and ulcerative colitis subjects. Gut 33: 507-512.
7. KETT K., T. O. ROGNUM, and P. BRANDTZAEG. 1987. Mucosal subclass distribution of immunoglobulin G-producing cells is different in ulcerative colitis and Crohn's disease of the colon. Gastroent. 93: 919-924.
8. MACDERMOTT R. P., and M. H. NAHM. 1987. Expression of human immunoglobulin G subclasses in inflammatory bowel disease. Gastroent. 93: 1127-1134.
9. MASON D. Y., C. J. M. VAN NOESEL, J. L. CORDELL, W. M. COMANS-BITTER, K. MICKLEM, A. G. D. TSE, R. A. W. VAN LIER, and J. J. M. VAN DONGEN. 1992. The B29 and mb-1 polypeptides are differentially expressed during human B-cell differentiation. Eur. J. Immunol. 22: 2753-2756.
10. MASON D. Y., J. L. CORDELL, M. H. BROWN, J. BORST, M. JONES, K. PULFORD, E. JAFFE, E. RALFKIAER, F. DALLENBACH, H. STEIN, S. PILERI, and K. C. GATTER. 1995. CD79a: A novel marker for B-cell neoplasms in routinely processed tissue samples. Blood 86 (4): 1453-1459.
11. GREENFIELD S. 1996. Treatment of Crohn's disease. Lancet 347: 1266-1267.
12. LINN F. V., M. A. PEPPERCORN. 1992. Drug therapy for inflammatory bowel disease: Part II. Am. J. Surg. 164: 178-185.
13. MACPHERSON A., U. Y. KHOO, I. FORGACS, J. PHILPOTT-HOWARD, I. BJARNASON. 1996. Mucosal antibodies in inflammatory bowel disease are directed against intestinal bacteria. Gut 38: 365-375.
14. BRANDTZAEG P., G. HARALDSEN, J. RUGTVEIT. 1997. Immunopathology of human inflammatory bowel disease. Springer Semin. Immunopathol. 18: 555-589.
15. MACDERMOTT R. P. 1994. Alterations in the mucosal immune system in ulcerative colitis and Crohn's disease. Med. Clin. North. Am. 78: 1207-1231.
16. BRAEGGER C. P. 1994. Immunopathogenesis of chronic inflammatory bowel disease. Acta Paediatr. Suppl. 395: 18-21.
17. HELGELAND L., C. TYSK, G. JÄRNEROT, K. KETT, E. LINDBERG, D. DANIELSSON, S. N. ANDERSEN, P. BRANDTZAEG. 1992. IgG subclass distribution in serum and rectal mucosa of monozygotic twins with or without inflammatory bowel disease. Gut 33: 1358-1364.
18. TARGAN S. R., C. J. LANDERS, L. COBB et al. 1995. Perinuclear anti-neutrophil cytoplamatic antibodies are spontaneously produced by mucosal B-cells of ulcerative colitis patients. J. Immunol. 155: 3262-3267.
19. BRANDTZAEG P., A. E. BERSTAD, I. N. FARSTADT, G. HARALDSEN, L. HELGELAND, F. L. JAHNSEN, F. E. JOHANSEN, I. B. NATVIG, E. M. NILSEN, J. RUGTVETT. 1997. Mucosal Immunity - a major adaptive defence mechanism. Behring Inst. Mitt., No. 98: 1-23.
20. SELDENRIJK M. A., S. G. M. MEUWISSEN, N. W. SCHIPPER, B. C. MORSON, J. LINDEMAN, C. J. L. M. MEIJER. 1992. Value of counting colonic mucosal Ig-containing cells in the differential diagnosis of chronic inflammatory bowel disease. J. Clin. Pathol. 45: 241-247.
21. MEUWISSEN S. G. M., T. M. FELTKAMP-VROOM, A. B. BRUTEL DE LA RIVIERE, A. E. VON DEM BORNE, and G. N. TYTGAT. 1976. Analysis of the lympho-plasmacytic infiltrate in Crohn's disease with special reference to identification of lymphocyte-subpopulations. Gut 17: 770-780.
22. BRANDTZAEG P., and K. BAKLIEN. 1976. Immunohistochemical studies of the formation and epithelial transport of immunoglobulins in normal and diseased human intestinal mucosa. Scan. J. Gastroent. 11, suppl. 36: 1-45.
23. YOUNT W. J., P. COHEN, and R. A. EISENBERG. 1988. Distribution of IgG, subclasses among human autoantibodies to Sm, RNP, dsDNA and IgG rheumatoid factor. Monogr. Allergy 23: 41.
24. GHARAVI A. E., E. N. HARRIS, M. D. LOCKSHIN et al. 1988. IgG subclass and light chain distribution of anticardiolipin and anti-DNA antibodies in SLE. Ann. Rheum. Dis. 47: 536.
25. HAMMARSTRÖM L., and C. SMITH. 1986. IgG subclasses in bacterial infections. Monogr. Allergy 19: 122.