Agonist antibody activates death receptor 6 downstream signaling involving TRADD recruitment

FEBS Letters

Volumn 588, Issue 3, 2014, Pages 401-407

  Hu, Rui ^a,b   Du, Qiumei ^a,b   Yin, Xiangyun ^a,b   Li, Jingyun ^a,b   Wang, Tingting ^c   Zhang, Liguo ^a  

^a INSTITUTE OF BIOPHYSICS   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^c GENERAL HOSPITAL OF NORTHERN THEATER COMMAND   (China)

Author keywords

Agonist antibody; Death domain; DR6; TRADD

Indexed keywords

DEATH RECEPTOR; DEATH RECEPTOR 6; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MONOCLONAL ANTIBODY; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED DEATH DOMAIN PROTEIN; UNCLASSIFIED DRUG;

ANTIGEN BINDING; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; EMBRYO; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FUNCTION; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION;

AGONIST ANTIBODY; C-JUN N-TERMINAL KINASE; CRD; CYSTEINE-RICH DOMAIN; DD; DEATH DOMAIN; DEATH RECEPTOR; DR; DR6; FADD; FAS-ASSOCIATED DEATH DOMAIN; JNK; N-APP; N-TERMINAL Β-AMYLOID PRECURSOR PROTEIN; SIRNA; SMALL INTERFERING RNA; TNFR; TNFR-ASSOCIATED DEATH DOMAIN PROTEIN; TRADD; TRAF; TUMOR NECROSIS FACTOR RECEPTOR; TUMOR NECROSIS FACTOR RECEPTOR-ASSOCIATED FACTOR;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANTIBODIES, MONOCLONAL; APOPTOSIS; HEK293 CELLS; HUMANS; NF-KAPPA B; RECEPTORS, TUMOR NECROSIS FACTOR; SIGNAL TRANSDUCTION; TNF RECEPTOR-ASSOCIATED DEATH DOMAIN PROTEIN; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84892811143     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1016/j.febslet.2013.12.010     Document Type: Article

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