Enhanced B cell expansion, survival, and humoral responses by targeting death receptor 6

Journal of Experimental Medicine

Volumn 197, Issue 1, 2003, Pages 51-62

  Schmidt, Clint S ^a   Liu, Jinqi ^a,b   Zhang, Tonghai ^a   Song, Ho Yeong ^a   Sandusky, George ^a   Mintze, Karen ^a   Benschop, Robert J ^a   Glasebrook, Andrew ^a   Yang, Derek D ^a   Na, Songqing ^a  

^a ELI LILLY AND COMPANY   (United States)

^b PHARMACOPEIA INC   (United States)

Author keywords

Apoptosis; CD40; Hyperproliferation; Spleen; TNFR superfamily

Indexed keywords

CD4 ANTIGEN; CD40 LIGAND MONOCLONAL ANTIBODY; CD86 ANTIGEN; CELL RECEPTOR; DEATH RECEPTOR 6; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; IMMUNOGLOBULIN M ANTIBODY; LIPOPOLYSACCHARIDE; PROTEIN BCL XL; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR REL; UNCLASSIFIED DRUG;

ALLOGENEIC RESTRICTION; ANIMAL CELL; ANTIBODY TITER; ANTIGEN PRESENTING CELL; APOPTOSIS; ARTICLE; B LYMPHOCYTE; CELL DIFFERENTIATION; CELL DIVISION; CELL FUNCTION; CELL PROLIFERATION; CELL SURVIVAL; DOWN REGULATION; GENE DISRUPTION; GENE TARGETING; GERMINAL CENTER; HUMORAL IMMUNITY; IMMUNOSTIMULATION; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; OBSERVATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN TARGETING; REGULATORY MECHANISM; SURFACE PROPERTY; TH2 CELL; WILD TYPE;

ANIMALS; ANTIGEN PRESENTATION; ANTIGENS, CD; ANTIGENS, CD86; APOPTOSIS; B-LYMPHOCYTES; BCL-X PROTEIN; CELL DIVISION; CELL SURVIVAL; CELLS, CULTURED; DOWN-REGULATION; FLOW CYTOMETRY; GENE DELETION; IMMUNOHISTOCHEMISTRY; LYMPHOCYTE ACTIVATION; MEMBRANE GLYCOPROTEINS; MICE; MICE, KNOCKOUT; MITOGENS; PROTO-ONCOGENE PROTEINS C-BCL-2; PROTO-ONCOGENE PROTEINS C-REL; RECEPTORS, TUMOR NECROSIS FACTOR; T-LYMPHOCYTES; UP-REGULATION;

EID: 0037243911     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.20020617     Document Type: Article

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