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Volumn 120, Issue SUPPL. 1, 2013, Pages

Is there a need to redefine Parkinson's disease?

Author keywords

Biomarker; Early diagnosis; Molecular biomarkers; Neuroimaging; Non motor symptoms; Parkinson's disease (PD); Premotor PD

Indexed keywords

BIOLOGICAL MARKER; MOLECULAR MARKER;

EID: 84892789293     PISSN: 03009564     EISSN: 14351463     Source Type: Journal    
DOI: 10.1007/s00702-013-1038-5     Document Type: Review
Times cited : (13)

References (101)
  • 1
    • 0035859865 scopus 로고    scopus 로고
    • Frequency of bowel movements and the future risk of Parkinson's disease
    • Abbott RD, Petrovitch H, White LR et al (2001) Frequency of bowel movements and the future risk of Parkinson's disease. Neurology 57:456-462
    • (2001) Neurology , vol.57 , pp. 456-462
    • Abbott, R.D.1    Petrovitch, H.2    White, L.R.3
  • 2
    • 27644439093 scopus 로고    scopus 로고
    • Excessive daytime sleepiness and subsequent development of Parkinson disease
    • Abbott RD, Ross GW, White LR et al (2005) Excessive daytime sleepiness and subsequent development of Parkinson disease. Neurology 65:1442-1446
    • (2005) Neurology , vol.65 , pp. 1442-1446
    • Abbott, R.D.1    Ross, G.W.2    White, L.R.3
  • 3
    • 34748826388 scopus 로고    scopus 로고
    • Bowel movement frequency in late-life and incidental Lewy bodies
    • Abbott RD, Ross GW, Petrovitch H et al (2007) Bowel movement frequency in late-life and incidental Lewy bodies. Mov Disord 22:1581-1586
    • (2007) Mov Disord , vol.22 , pp. 1581-1586
    • Abbott, R.D.1    Ross, G.W.2    Petrovitch, H.3
  • 4
    • 84858144224 scopus 로고    scopus 로고
    • Penetrance of Parkinson disease in glucocerebrosidase gene mutation carriers
    • Anheim M, Elbaz A, Lesage S et al (2012) Penetrance of Parkinson disease in glucocerebrosidase gene mutation carriers. Neurology 78:417-420
    • (2012) Neurology , vol.78 , pp. 417-420
    • Anheim, M.1    Elbaz, A.2    Lesage, S.3
  • 5
    • 69949153066 scopus 로고    scopus 로고
    • The PRIAMO study: A multicenter assessment of nonmotor symptoms and their impact on quality of life in Parkinson's disease
    • Barone P, Antonini A, Colosimo C et al (2009) The PRIAMO study: a multicenter assessment of nonmotor symptoms and their impact on quality of life in Parkinson's disease. Mov Disord 24:1641-1649
    • (2009) Mov Disord , vol.24 , pp. 1641-1649
    • Barone, P.1    Antonini, A.2    Colosimo, C.3
  • 6
    • 84872870323 scopus 로고    scopus 로고
    • Submandibular gland biopsy for the diagnosis of Parkinson disease
    • Beach TG, Adler CH, Dugger BN et al (2013) Submandibular gland biopsy for the diagnosis of Parkinson disease. J Neuropathol Exp Neurol 72:130-136
    • (2013) J Neuropathol Exp Neurol , vol.72 , pp. 130-136
    • Beach, T.G.1    Adler, C.H.2    Dugger, B.N.3
  • 7
    • 67651161861 scopus 로고    scopus 로고
    • Hyperechogenicity of the substantia nigra in healthy controls is related to MRI changes and to neuronal loss as determined by F-Dopa PET
    • Behnke S, Schroeder U, Dillmann U et al (2009) Hyperechogenicity of the substantia nigra in healthy controls is related to MRI changes and to neuronal loss as determined by F-Dopa PET. Neuroimage 47:1237-1243
    • (2009) Neuroimage , vol.47 , pp. 1237-1243
    • Behnke, S.1    Schroeder, U.2    Dillmann, U.3
  • 8
    • 84876030967 scopus 로고    scopus 로고
    • Long-term course of substantia nigra hyperechogenicity in Parkinson's disease
    • doi:10.1002/mds.25193
    • Behnke S, Runkel A, Kassar HA et al (2012) Long-term course of substantia nigra hyperechogenicity in Parkinson's disease. Mov Disord 28(4):455-459. doi:10.1002/mds.25193
    • (2012) Mov Disord , vol.28 , Issue.4 , pp. 455-459
    • Behnke, S.1    Runkel, A.2    Kassar, H.A.3
  • 9
    • 0030043663 scopus 로고    scopus 로고
    • Prevalence of Parkinsonian signs and associated mortality in a community population of older people
    • Bennett DA, Beckett LA, Murray AM (1996) Prevalence of Parkinsonian signs and associated mortality in a community population of older people. N Engl J Med 334:71-76
    • (1996) N Engl J Med , vol.334 , pp. 71-76
    • Bennett, D.A.1    Beckett, L.A.2    Murray, A.M.3
  • 10
    • 84859812869 scopus 로고    scopus 로고
    • Can we define "pre-motor" Parkinson's disease?
    • Berg D, Poewe W (2012) Can we define "pre-motor" Parkinson's disease? Mov Disord 27:595-596
    • (2012) Mov Disord , vol.27 , pp. 595-596
    • Berg, D.1    Poewe, W.2
  • 11
    • 0033595447 scopus 로고    scopus 로고
    • Vulnerability of the nigrostriatal system as detected by transcranial ultrasound
    • Berg D, Becker G, Zeiler B et al (1999) Vulnerability of the nigrostriatal system as detected by transcranial ultrasound. Neurology 53:1026-1031
    • (1999) Neurology , vol.53 , pp. 1026-1031
    • Berg, D.1    Becker, G.2    Zeiler, B.3
  • 12
    • 0036279410 scopus 로고    scopus 로고
    • Echogenicity of the substantia nigra: Association with increased iron content and marker for susceptibility to nigrostriatal injury
    • Berg D, Roggendorf W, Schroder U et al (2002) Echogenicity of the substantia nigra: association with increased iron content and marker for susceptibility to nigrostriatal injury. Arch Neurol 59:999-1005
    • (2002) Arch Neurol , vol.59 , pp. 999-1005
    • Berg, D.1    Roggendorf, W.2    Schroder, U.3
  • 13
    • 53649086350 scopus 로고    scopus 로고
    • Transcranial sonography in movement disorders
    • Berg D, Godau J, Walter U (2008) Transcranial sonography in movement disorders. Lancet Neurol 7:1044-1055
    • (2008) Lancet Neurol , vol.7 , pp. 1044-1055
    • Berg, D.1    Godau, J.2    Walter, U.3
  • 14
    • 79960173762 scopus 로고    scopus 로고
    • Enlarged substantia nigra hyperechogenicity and risk for Parkinson disease: A 37-month 3-center study of 1847 older persons
    • Berg D, Seppi K, Behnke S et al (2011) Enlarged substantia nigra hyperechogenicity and risk for Parkinson disease: a 37-month 3-center study of 1847 older persons. Arch Neurol 68:932-937
    • (2011) Arch Neurol , vol.68 , pp. 932-937
    • Berg, D.1    Seppi, K.2    Behnke, S.3
  • 15
    • 84859846991 scopus 로고    scopus 로고
    • Defining at-risk populations for Parkinson's disease: Lessons from ongoing studies
    • Berg D, Marek K, Ross GW, Poewe W (2012) Defining at-risk populations for Parkinson's disease: lessons from ongoing studies. Mov Disord 27:656-665
    • (2012) Mov Disord , vol.27 , pp. 656-665
    • Berg, D.1    Marek, K.2    Ross, G.W.3    Poewe, W.4
  • 16
    • 84876464458 scopus 로고    scopus 로고
    • Changing the research criteria for the diagnosis of Parkinson's disease: Obstacles and opportunities
    • Berg D, Lang AE, Postuma R et al (2013a) Changing the research criteria for the diagnosis of Parkinson's disease: obstacles and opportunities. Lancet Neurol 12(5):514-524
    • (2013) Lancet Neurol , vol.12 , Issue.5 , pp. 514-524
    • Berg, D.1    Lang, A.E.2    Postuma, R.3
  • 17
    • 84874208978 scopus 로고    scopus 로고
    • Enlarged hyperechogenic substantia nigra as a risk marker for Parkinson's disease
    • Berg D, Behnke S, Seppi K et al (2013b) Enlarged hyperechogenic substantia nigra as a risk marker for Parkinson's disease. Mov Disord 28:216-219
    • (2013) Mov Disord , vol.28 , pp. 216-219
    • Berg, D.1    Behnke, S.2    Seppi, K.3
  • 18
    • 84871665722 scopus 로고    scopus 로고
    • The PRIPS study: Screening battery for subjects at risk for Parkinson's disease
    • Berg D, Godau J, Seppi K et al (2013c) The PRIPS study: screening battery for subjects at risk for Parkinson's disease. Eur J Neurol 20:102-108
    • (2013) Eur J Neurol , vol.20 , pp. 102-108
    • Berg, D.1    Godau, J.2    Seppi, K.3
  • 19
    • 84873641251 scopus 로고    scopus 로고
    • Naturally occurring asynuclein autoantibody levels are lower in patients with Parkinson disease
    • Besong-Agbo D, Wolf E, Jessen F et al (2013) Naturally occurring asynuclein autoantibody levels are lower in patients with Parkinson disease. Neurology 80:169-175
    • (2013) Neurology , vol.80 , pp. 169-175
    • Besong-Agbo, D.1    Wolf, E.2    Jessen, F.3
  • 20
    • 0037384803 scopus 로고    scopus 로고
    • Presymptomatic compensation in Parkinson's disease is not dopamine-mediated
    • Bezard E, Gross CE, Brotchie JM (2003) Presymptomatic compensation in Parkinson's disease is not dopamine-mediated. Trends Neurosci 26:215-221
    • (2003) Trends Neurosci , vol.26 , pp. 215-221
    • Bezard, E.1    Gross, C.E.2    Brotchie, J.M.3
  • 21
    • 84865055362 scopus 로고    scopus 로고
    • Expression pattern and localization of alpha-synuclein in the human enteric nervous system
    • Böttner M, Zorenkov D, Hellwig I et al (2012) Expression pattern and localization of alpha-synuclein in the human enteric nervous system. Neurobiol Dis 48:474-480
    • (2012) Neurobiol Dis , vol.48 , pp. 474-480
    • Böttner, M.1    Zorenkov, D.2    Hellwig, I.3
  • 23
    • 84857536339 scopus 로고    scopus 로고
    • Nigral pathology and parkinsonian signs in elders without Parkinson disease
    • Buchman AS, Shulman JM, Nag S et al (2012) Nigral pathology and parkinsonian signs in elders without Parkinson disease. Ann Neurol 71:258-266
    • (2012) Ann Neurol , vol.71 , pp. 258-266
    • Buchman, A.S.1    Shulman, J.M.2    Nag, S.3
  • 24
    • 79955389388 scopus 로고    scopus 로고
    • Plasma epidermal growth factor levels predict cognitive decline in Parkinson disease
    • Chen-Plotkin AS, Hu WT, Siderowf A et al (2010) Plasma epidermal growth factor levels predict cognitive decline in Parkinson disease. Ann Neurol 69:655-663
    • (2010) Ann Neurol , vol.69 , pp. 655-663
    • Chen-Plotkin, A.S.1    Hu, W.T.2    Siderowf, A.3
  • 25
    • 36249014257 scopus 로고    scopus 로고
    • Sleep disorders in Parkinson's disease: An overview
    • Comella CL (2007) Sleep disorders in Parkinson's disease: an overview. Mov Disord 22(S17):367-373
    • (2007) Mov Disord , vol.22 , Issue.S17 , pp. 367-373
    • Comella, C.L.1
  • 26
    • 84859834711 scopus 로고    scopus 로고
    • Lewy pathology and neurodegeneration in premotor Parkinson's disease
    • Del TK, Braak H (2012) Lewy pathology and neurodegeneration in premotor Parkinson's disease. Mov Disord 27:597-607
    • (2012) Mov Disord , vol.27 , pp. 597-607
    • Del, T.K.1    Braak, H.2
  • 27
    • 79958233724 scopus 로고    scopus 로고
    • Salivary alpha-synuclein and DJ-1: Potential biomarkers for Parkinson's disease
    • Devic I, Hwang H, Edgar JS et al (2011) Salivary alpha-synuclein and DJ-1: potential biomarkers for Parkinson's disease. Brain 134:e178
    • (2011) Brain , vol.134
    • Devic, I.1    Hwang, H.2    Edgar, J.S.3
  • 28
    • 41149115508 scopus 로고    scopus 로고
    • Evidence that incidental Lewy body disease is pre-symptomatic Parkinson's disease
    • Dickson DW, Fujishiro H, DelleDonne A et al (2008) Evidence that incidental Lewy body disease is pre-symptomatic Parkinson's disease. Acta Neuropathol 115:437-444
    • (2008) Acta Neuropathol , vol.115 , pp. 437-444
    • Dickson, D.W.1    Fujishiro, H.2    Delledonne, A.3
  • 29
    • 71849092190 scopus 로고    scopus 로고
    • Neuropathological assessment of Parkinson's disease: Refining the diagnostic criteria
    • Dickson DW, Braak H, Duda JE et al (2009) Neuropathological assessment of Parkinson's disease: refining the diagnostic criteria. Lancet Neurol 8:1150-1157
    • (2009) Lancet Neurol , vol.8 , pp. 1150-1157
    • Dickson, D.W.1    Braak, H.2    Duda, J.E.3
  • 30
    • 84871251285 scopus 로고    scopus 로고
    • Non-motor symptoms in early Parkinson's disease: A 2-year follow-up study on previously untreated patients
    • Erro R, Picillo M, Vitale C et al (2013) Non-motor symptoms in early Parkinson's disease: a 2-year follow-up study on previously untreated patients. J Neurol Neurosurg Psychiatry 84:14-17
    • (2013) J Neurol Neurosurg Psychiatry , vol.84 , pp. 14-17
    • Erro, R.1    Picillo, M.2    Vitale, C.3
  • 31
    • 0025954066 scopus 로고
    • Ageing and Parkinson's disease: Substantia nigra regional selectivity
    • Fearnley JM, Lees AJ (1991) Ageing and Parkinson's disease: substantia nigra regional selectivity. Brain 114:2283-2301
    • (1991) Brain , vol.114 , pp. 2283-2301
    • Fearnley, J.M.1    Lees, A.J.2
  • 32
    • 82655171636 scopus 로고    scopus 로고
    • Phosphorylated a-synuclein can be detected in blood plasma and is potentially a useful biomarker for Parkinson's disease
    • Foulds PG, Mitchell JD, Parker A (2011) Phosphorylated a-synuclein can be detected in blood plasma and is potentially a useful biomarker for Parkinson's disease. FASEB 25:4127-4137
    • (2011) FASEB , vol.25 , pp. 4127-4137
    • Foulds, P.G.1    Mitchell, J.D.2    Parker, A.3
  • 33
    • 84862775133 scopus 로고    scopus 로고
    • Investigation of autonomic function in idiopathic REM sleep behavior disorder
    • Frauscher B, Nomura T, Duerr S et al (2012) Investigation of autonomic function in idiopathic REM sleep behavior disorder. J Neurol 259:1056-1061
    • (2012) J Neurol , vol.259 , pp. 1056-1061
    • Frauscher, B.1    Nomura, T.2    Duerr, S.3
  • 34
    • 79955466566 scopus 로고    scopus 로고
    • Agespecific progression of nigrostriatal dysfunction in Parkinson's disease
    • Fuente-Fernandez R, Schulzer M, Kuramoto L et al (2011) Agespecific progression of nigrostriatal dysfunction in Parkinson's disease. Ann Neurol 69:803-810
    • (2011) Ann Neurol , vol.69 , pp. 803-810
    • Fuente-Fernandez, R.1    Schulzer, M.2    Kuramoto, L.3
  • 35
  • 36
    • 0023898945 scopus 로고
    • The relevance of the Lewy body to the pathogenesis of idiopathic Parkinson's disease
    • Gibb WR, Lees AJ (1988) The relevance of the Lewy body to the pathogenesis of idiopathic Parkinson's disease. J Neurol Neurosurg Psychiatry 51:745-752
    • (1988) J Neurol Neurosurg Psychiatry , vol.51 , pp. 745-752
    • Gibb, W.R.1    Lees, A.J.2
  • 37
    • 84859877206 scopus 로고    scopus 로고
    • Neuroimaging: Current role in detecting pre-motor Parkinson's disease
    • Godau J, Hussl A, Lolekha P, Stoessl AJ, Seppi K et al (2012) Neuroimaging: current role in detecting pre-motor Parkinson's disease. Mov Disord 27:634-643
    • (2012) Mov Disord , vol.27 , pp. 634-643
    • Godau, J.1    Hussl, A.2    Lolekha, P.3    Stoessl, A.J.4    Seppi, K.5
  • 38
    • 33645749795 scopus 로고    scopus 로고
    • Motor score of the unified Parkinson disease rating scale as a good predictor of Lewy body-associated neuronal loss in the substantia nigra
    • Greffard S, Verny M, Bonnet AM et al (2006) Motor score of the unified Parkinson disease rating scale as a good predictor of Lewy body-associated neuronal loss in the substantia nigra. Arch Neurol 63:584-588
    • (2006) Arch Neurol , vol.63 , pp. 584-588
    • Greffard, S.1    Verny, M.2    Bonnet, A.M.3
  • 40
    • 67650753670 scopus 로고    scopus 로고
    • Prevalence of smell loss in Parkinson's disease-A multicenter study
    • Haehner A, Boesveldt S, Berendse HW (2009) Prevalence of smell loss in Parkinson's disease-a multicenter study. Parkinsonism Relat Disord 15:490-494
    • (2009) Parkinsonism Relat Disord , vol.15 , pp. 490-494
    • Haehner, A.1    Boesveldt, S.2    Berendse, H.W.3
  • 41
    • 14844300111 scopus 로고    scopus 로고
    • Nonlinear progression of Parkinson disease as determined by serial positron emission tomographic imaging of striatal fluoro dopa F 18 activity
    • Hilker R, Schweitzer K, Coburger S et al (2005) Nonlinear progression of Parkinson disease as determined by serial positron emission tomographic imaging of striatal fluoro dopa F 18 activity. Arch Neurol 62:378-382
    • (2005) Arch Neurol , vol.62 , pp. 378-382
    • Hilker, R.1    Schweitzer, K.2    Coburger, S.3
  • 42
    • 77950223687 scopus 로고    scopus 로고
    • DJ-1 and alpha-synuclein in human cerebrospinal fluid as biomarkers of Parkinson's disease
    • Hong Z, Shi M, Chung KA et al (2010) DJ-1 and alpha-synuclein in human cerebrospinal fluid as biomarkers of Parkinson's disease. Brain 133:713-726
    • (2010) Brain , vol.133 , pp. 713-726
    • Hong, Z.1    Shi, M.2    Chung, K.A.3
  • 43
    • 79951811351 scopus 로고    scopus 로고
    • Imputation of sequence variants for identification of genetic risks for Parkinson's disease: A meta-analysis of genome-wide association studies
    • International Parkinson Disease Genomics Consortium
    • International Parkinson Disease Genomics Consortium, Nalls MA, Plagnol V, Hernandez DG et al (2011) Imputation of sequence variants for identification of genetic risks for Parkinson's disease: a meta-analysis of genome-wide association studies. Lancet 377:641-649
    • (2011) Lancet , vol.377 , pp. 641-649
    • Nalls, M.A.1    Plagnol, V.2    Hernandez, D.G.3
  • 44
    • 33744991945 scopus 로고    scopus 로고
    • Rapid-eyemovement sleep behaviour disorder as an early marker for a neurodegenerative disorder: A descriptive study
    • Iranzo A, Molinuevo JL, Santamaria J et al (2006) Rapid-eyemovement sleep behaviour disorder as an early marker for a neurodegenerative disorder: a descriptive study. Lancet Neurol 5:572-577
    • (2006) Lancet Neurol , vol.5 , pp. 572-577
    • Iranzo, A.1    Molinuevo, J.L.2    Santamaria, J.3
  • 45
    • 80051665062 scopus 로고    scopus 로고
    • Serial dopamine transporter imaging of nigrostriatal function in patients with idiopathic rapid-eye-movement sleep behaviour disorder: A prospective study
    • Iranzo A, Valldeoriola F, Lomena F et al (2011) Serial dopamine transporter imaging of nigrostriatal function in patients with idiopathic rapid-eye-movement sleep behaviour disorder: a prospective study. Lancet Neurol 10:797-805
    • (2011) Lancet Neurol , vol.10 , pp. 797-805
    • Iranzo, A.1    Valldeoriola, F.2    Lomena, F.3
  • 46
    • 33644898837 scopus 로고    scopus 로고
    • A systematic review of depression and mental illness preceding Parkinson's disease
    • Ishihara L, Brayne C (2006) A systematic review of depression and mental illness preceding Parkinson's disease. Acta Neurol Scand 113:211-220
    • (2006) Acta Neurol Scand , vol.113 , pp. 211-220
    • Ishihara, L.1    Brayne, C.2
  • 47
    • 84863728773 scopus 로고    scopus 로고
    • Therapies in Parkinson's disease
    • Jankovic J, Poewe W (2012) Therapies in Parkinson's disease. Curr Opin Neurol 25:433-447
    • (2012) Curr Opin Neurol , vol.25 , pp. 433-447
    • Jankovic, J.1    Poewe, W.2
  • 48
    • 84888206034 scopus 로고    scopus 로고
    • Association between CSF biomarkers and clinical phenotype of early Parkinson's disease in the Parkinson's Progression Marker Initiative (PPMI)
    • Kang JH, Caspell C, Coffey C et al (2012) Association between CSF biomarkers and clinical phenotype of early Parkinson's disease in the Parkinson's Progression Marker Initiative (PPMI). Mov Disord 27(S1):34-35
    • (2012) Mov Disord , vol.27 , Issue.S1 , pp. 34-35
    • Kang, J.H.1    Caspell, C.2    Coffey, C.3
  • 49
    • 4043098888 scopus 로고    scopus 로고
    • Olfaction and Parkinson's syndromes: Its role in differential diagnosis
    • Katzenschlager R, Lees AJ (2004) Olfaction and Parkinson's syndromes: its role in differential diagnosis. Curr Opin Neurol 17:417-423
    • (2004) Curr Opin Neurol , vol.17 , pp. 417-423
    • Katzenschlager, R.1    Lees, A.J.2
  • 50
    • 84873660450 scopus 로고    scopus 로고
    • The spectrum of nonmotor symptoms in early Parkinson disease
    • Khoo TK, Yarnall AJ, Duncan GW (2013) The spectrum of nonmotor symptoms in early Parkinson disease. Neurology 80:276-281
    • (2013) Neurology , vol.80 , pp. 276-281
    • Khoo, T.K.1    Yarnall, A.J.2    Duncan, G.W.3
  • 52
    • 0035037328 scopus 로고    scopus 로고
    • Use of biomarkers and surrogate endpoints in drug development and regulatory decision making: Criteria, validation, strategies
    • Lesko LJ, Atkinson AJ Jr (2001) Use of biomarkers and surrogate endpoints in drug development and regulatory decision making: criteria, validation, strategies. Annu Rev Pharmacol Toxicol 41:347-366
    • (2001) Annu Rev Pharmacol Toxicol , vol.41 , pp. 347-366
    • Lesko, L.J.1    Atkinson Jr., A.J.2
  • 53
    • 84859339977 scopus 로고    scopus 로고
    • Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: The PDGene database
    • Lill CM, Roehr JT, McQueen MB et al (2012) Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: the PDGene database. PLoS Genet 8:e1002548
    • (2012) PLoS Genet , vol.8
    • Lill, C.M.1    Roehr, J.T.2    McQueen, M.B.3
  • 54
    • 35348943900 scopus 로고    scopus 로고
    • Mild Parkinsonian signs: An overview of an emerging concept
    • Louis ED, Bennett DA (2007) Mild Parkinsonian signs: an overview of an emerging concept. Mov Disord 22:1681-1688
    • (2007) Mov Disord , vol.22 , pp. 1681-1688
    • Louis, E.D.1    Bennett, D.A.2
  • 55
    • 84859856337 scopus 로고    scopus 로고
    • Motor signs in the prodromal phase of Parkinson's disease
    • Maetzler W, Hausdorff JM (2012) Motor signs in the prodromal phase of Parkinson's disease. Mov Disord 27:627-633
    • (2012) Mov Disord , vol.27 , pp. 627-633
    • Maetzler, W.1    Hausdorff, J.M.2
  • 56
    • 84858785464 scopus 로고    scopus 로고
    • Impaired trunk stability in individuals at high risk for Parkinson's disease
    • Maetzler W, Mancini M, Liepelt-Scarfone I et al (2012) Impaired trunk stability in individuals at high risk for Parkinson's disease. PLoS ONE 7:e32240
    • (2012) PLoS ONE , vol.7
    • Maetzler, W.1    Mancini, M.2    Liepelt-Scarfone, I.3
  • 57
    • 84864758540 scopus 로고    scopus 로고
    • A follow-up study of substantia nigra echogenicity in healthy adults
    • Mahlknecht P, Stockner H, Nocker M et al (2012) A follow-up study of substantia nigra echogenicity in healthy adults. Mov Disord 27:1196-1197
    • (2012) Mov Disord , vol.27 , pp. 1196-1197
    • Mahlknecht, P.1    Stockner, H.2    Nocker, M.3
  • 58
    • 0035846468 scopus 로고    scopus 로고
    • [123I]beta-CIT SPECT imaging assessment of the rate of Parkinson's disease progression
    • Marek K, Innis R, van DC et al (2001) [123I]beta-CIT SPECT imaging assessment of the rate of Parkinson's disease progression. Neurology 57:2089-2094
    • (2001) Neurology , vol.57 , pp. 2089-2094
    • Marek, K.1    Innis, R.2    Van, D.C.3
  • 59
    • 79956142378 scopus 로고    scopus 로고
    • The diagnosis of dementia due to Alzheimer's disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease
    • McKhann GM, Knopman DS, Chertkow H et al (2011) The diagnosis of dementia due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimers Dement 7:263-269
    • (2011) Alzheimers Dement , vol.7 , pp. 263-269
    • McKhann, G.M.1    Knopman, D.S.2    Chertkow, H.3
  • 60
    • 73649125445 scopus 로고    scopus 로고
    • Clinical availability of skin biopsy in the diagnosis of Parkinson's disease
    • Miki Y, Tomiyama M, Ueno T, Haga R et al (2010) Clinical availability of skin biopsy in the diagnosis of Parkinson's disease. Neurosci Lett 469:357-359
    • (2010) Neurosci Lett , vol.469 , pp. 357-359
    • Miki, Y.1    Tomiyama, M.2    Ueno, T.3    Haga, R.4
  • 62
    • 84859819081 scopus 로고    scopus 로고
    • Biochemical premotor biomarkers for Parkinson's disease
    • Mollenhauer B, Zhang J (2012) Biochemical premotor biomarkers for Parkinson's disease. Mov Disord 27:644-650
    • (2012) Mov Disord , vol.27 , pp. 644-650
    • Mollenhauer, B.1    Zhang, J.2
  • 64
    • 0031898680 scopus 로고    scopus 로고
    • Measuring the rate of progression and estimating the preclinical period of Parkinson's disease with [18F]dopa PET
    • Morrish PK, Rakshi JS, Bailey DL, Sawle GV, Brooks DJ (1998) Measuring the rate of progression and estimating the preclinical period of Parkinson's disease with [18F]dopa PET. J Neurol Neurosurg Psychiatry 64:314-319
    • (1998) J Neurol Neurosurg Psychiatry , vol.64 , pp. 314-319
    • Morrish, P.K.1    Rakshi, J.S.2    Bailey, D.L.3    Sawle, G.V.4    Brooks, D.J.5
  • 65
    • 84872003490 scopus 로고    scopus 로고
    • Metaanalysis of early nonmotor features and risk factors for Parkinson disease
    • Noyce AJ, Bestwick JP, Silveira-Moriyama L et al (2012) Metaanalysis of early nonmotor features and risk factors for Parkinson disease. Ann Neurol 72:893-901
    • (2012) Ann Neurol , vol.72 , pp. 893-901
    • Noyce, A.J.1    Bestwick, J.P.2    Silveira-Moriyama, L.3
  • 67
    • 82755161902 scopus 로고    scopus 로고
    • The Parkinson Progression Marker Initiative (PPMI)
    • Parkinson Progression Marker Initiative
    • Parkinson Progression Marker Initiative (2011) The Parkinson Progression Marker Initiative (PPMI). Prog Neurobiol 95: 629-635
    • (2011) Prog Neurobiol , vol.95 , pp. 629-635
  • 68
    • 41049106214 scopus 로고    scopus 로고
    • Non-motor symptoms in Parkinson's disease
    • Poewe W (2008) Non-motor symptoms in Parkinson's disease. Eur J Neurol 15(S1):14-20
    • (2008) Eur J Neurol , vol.15 , Issue.S1 , pp. 14-20
    • Poewe, W.1
  • 70
    • 77950601138 scopus 로고    scopus 로고
    • Olfactory testing combined with dopamine transporter imaging as a method to detect prodromal Parkinson's disease
    • Ponsen MM, Stoffers D, Wolters ECh, Booij J, Berendse HW (2010) Olfactory testing combined with dopamine transporter imaging as a method to detect prodromal Parkinson's disease. J Neurol Neurosurg Psychiatry 81:396-399
    • (2010) J Neurol Neurosurg Psychiatry , vol.81 , pp. 396-399
    • Ponsen, M.M.1    Stoffers, D.2    Wolters, E.C.H.3    Booij, J.4    Berendse, H.W.5
  • 71
    • 33645836498 scopus 로고    scopus 로고
    • Potential early markers of Parkinson disease in idiopathic REM sleep behavior disorder
    • Postuma RB, Lang AE, Massicotte-Marquez J, Montplaisir J (2006) Potential early markers of Parkinson disease in idiopathic REM sleep behavior disorder. Neurology 66:845-851
    • (2006) Neurology , vol.66 , pp. 845-851
    • Postuma, R.B.1    Lang, A.E.2    Massicotte-Marquez, J.3    Montplaisir, J.4
  • 73
    • 79955485357 scopus 로고    scopus 로고
    • Olfaction and color vision identify impending neurodegeneration in REM behavior disorder
    • Postuma RB, Gagnon JF, Vendette M, Desjardins C, Montplaisir J (2011) Olfaction and color vision identify impending neurodegeneration in REM behavior disorder. Ann Neurol 69:811-818
    • (2011) Ann Neurol , vol.69 , pp. 811-818
    • Postuma, R.B.1    Gagnon, J.F.2    Vendette, M.3    Desjardins, C.4    Montplaisir, J.5
  • 74
    • 84861561293 scopus 로고    scopus 로고
    • How does Parkinsonism start? Prodromal Parkinsonism motor changes in idiopathic REM sleep behavior disorder
    • Postuma RB, Lang AE, Gagnon JF, Pelletier A, Montplaisir JY (2012a) How does Parkinsonism start? Prodromal Parkinsonism motor changes in idiopathic REM sleep behavior disorder. Brain 135:1860-1870
    • (2012) Brain , vol.135 , pp. 1860-1870
    • Postuma, R.B.1    Lang, A.E.2    Gagnon, J.F.3    Pelletier, A.4    Montplaisir, J.Y.5
  • 75
    • 84859874695 scopus 로고    scopus 로고
    • Identifying prodromal Parkinson's disease: Pre-motor disorders in Parkinson's disease
    • Postuma RB, Aarsland D, Barone P et al (2012b) Identifying prodromal Parkinson's disease: pre-motor disorders in Parkinson's disease. Mov Disord 27:617-626
    • (2012) Mov Disord , vol.27 , pp. 617-626
    • Postuma, R.B.1    Aarsland, D.2    Barone, P.3
  • 76
    • 84883303537 scopus 로고    scopus 로고
    • Plasma apolipoprotein A1 as a biomarker for Parkinson's disease
    • doi: 10.1002/ana.23872. [Epub ahead of print]
    • Qiang JK, Wong YC, Siderowf A et al (2013) Plasma apolipoprotein A1 as a biomarker for Parkinson's disease. Ann Neurol. doi: 10.1002/ana.23872. [Epub ahead of print]
    • (2013) Ann Neurol
    • Qiang, J.K.1    Wong, Y.C.2    Siderowf, A.3
  • 77
    • 35948933394 scopus 로고    scopus 로고
    • Classification and prediction of clinical Alzheimer's diagnosis based on plasma signaling proteins
    • Ray S, Britschgi M, Herbert C et al (2007) Classification and prediction of clinical Alzheimer's diagnosis based on plasma signaling proteins. Nat Med 13:1359-1362
    • (2007) Nat Med , vol.13 , pp. 1359-1362
    • Ray, S.1    Britschgi, M.2    Herbert, C.3
  • 78
    • 39749146383 scopus 로고    scopus 로고
    • A systematic review of prevalence studies of depression in Parkinson's disease
    • Reijnders JS, Ehrt U, Weber WE, Aarsland D, Leentjens AF (2008) A systematic review of prevalence studies of depression in Parkinson's disease. Mov Disord 23:183-189
    • (2008) Mov Disord , vol.23 , pp. 183-189
    • Reijnders, J.S.1    Ehrt, U.2    Weber, W.E.3    Aarsland, D.4    Leentjens, A.F.5
  • 79
    • 4844226577 scopus 로고    scopus 로고
    • Parkinsonian signs and substantia nigra neuron density in descendents elders without PD
    • Ross GW, Petrovitch H, Abbott RD et al (2004) Parkinsonian signs and substantia nigra neuron density in descendents elders without PD. Ann Neurol 56:532-539
    • (2004) Ann Neurol , vol.56 , pp. 532-539
    • Ross, G.W.1    Petrovitch, H.2    Abbott, R.D.3
  • 80
    • 33749022060 scopus 로고    scopus 로고
    • Association of olfactory dysfunction with incidental Lewy bodies
    • Ross GW, Abbott RD, Petrovitch H et al (2006) Association of olfactory dysfunction with incidental Lewy bodies. Mov Disord 21:2062-2067
    • (2006) Mov Disord , vol.21 , pp. 2062-2067
    • Ross, G.W.1    Abbott, R.D.2    Petrovitch, H.3
  • 81
    • 40449083312 scopus 로고    scopus 로고
    • Association of olfactory dysfunction with risk for future Parkinson's disease
    • Ross GW, Petrovitch H, Abbott RD et al (2008) Association of olfactory dysfunction with risk for future Parkinson's disease. Ann Neurol. 63:167-173
    • (2008) Ann Neurol. , vol.63 , pp. 167-173
    • Ross, G.W.1    Petrovitch, H.2    Abbott, R.D.3
  • 82
    • 73349092154 scopus 로고    scopus 로고
    • Medical records documentation of constipation preceding Parkinson disease: A case-control study
    • Savica R, Carlin JM, Grossardt BR et al (2009) Medical records documentation of constipation preceding Parkinson disease: a case-control study. Neurology 73:1752-1758
    • (2009) Neurology , vol.73 , pp. 1752-1758
    • Savica, R.1    Carlin, J.M.2    Grossardt, B.R.3
  • 83
    • 0022982498 scopus 로고
    • Chronic behavioral disorders of human REM sleep: A new category of parasomnia
    • Schenck CH, Bundlie SR, Ettinger MG, Mahowald MW (1986) Chronic behavioral disorders of human REM sleep: a new category of parasomnia. Sleep 9:293-308
    • (1986) Sleep , vol.9 , pp. 293-308
    • Schenck, C.H.1    Bundlie, S.R.2    Ettinger, M.G.3    Mahowald, M.W.4
  • 84
    • 79952523298 scopus 로고    scopus 로고
    • White and gray matter abnormalities in idiopathic rapid eye movement sleep behavior disorder: A diffusion-tensor imaging and voxel-based morphometry study
    • Scherfler C, Frauscher B, Schocke M et al (2011) White and gray matter abnormalities in idiopathic rapid eye movement sleep behavior disorder: a diffusion-tensor imaging and voxel-based morphometry study. Ann Neurol 69:400-407
    • (2011) Ann Neurol , vol.69 , pp. 400-407
    • Scherfler, C.1    Frauscher, B.2    Schocke, M.3
  • 85
    • 84861692236 scopus 로고    scopus 로고
    • Alphasynuclein in colonic submucosa in early untreated Parkinson's disease
    • Shannon KM, Keshavarzian A, Mutlu E et al (2012a) Alphasynuclein in colonic submucosa in early untreated Parkinson's disease. Mov Disord 27:709-715
    • (2012) Mov Disord , vol.27 , pp. 709-715
    • Shannon, K.M.1    Keshavarzian, A.2    Mutlu, E.3
  • 86
    • 84861697687 scopus 로고    scopus 로고
    • Is alpha-synuclein in the colon a biomarker for premotor Parkinson's disease? Evidence from 3 cases
    • Shannon KM, Keshavarzian A, Dodiya HB, Jakate S, Kordower JH (2012b) Is alpha-synuclein in the colon a biomarker for premotor Parkinson's disease? Evidence from 3 cases. Mov Disord 27:716-719
    • (2012) Mov Disord , vol.27 , pp. 716-719
    • Shannon, K.M.1    Keshavarzian, A.2    Dodiya, H.B.3    Jakate, S.4    Kordower, J.H.5
  • 87
    • 77954384099 scopus 로고    scopus 로고
    • Significance and confounders of peripheral DJ-1 and alpha-synuclein in Parkinson's disease
    • Shi M, Zabetian CP, Hancock AM et al (2010) Significance and confounders of peripheral DJ-1 and alpha-synuclein in Parkinson's disease. Neurosci Lett 480:78-82
    • (2010) Neurosci Lett , vol.480 , pp. 78-82
    • Shi, M.1    Zabetian, C.P.2    Hancock, A.M.3
  • 88
    • 79953283868 scopus 로고    scopus 로고
    • Cerebrospinal fluid biomarkers for Parkinson disease diagnosis and progression
    • Shi M, Bradner J, Hancock AM et al (2011) Cerebrospinal fluid biomarkers for Parkinson disease diagnosis and progression. Ann Neurol 69:570-580
    • (2011) Ann Neurol , vol.69 , pp. 570-580
    • Shi, M.1    Bradner, J.2    Hancock, A.M.3
  • 89
    • 0033925871 scopus 로고    scopus 로고
    • Anxiety disorders and depressive disorders preceding Parkinson's disease: A casecontrol study
    • Shiba M, Bower JH, Maraganore DM et al (2000) Anxiety disorders and depressive disorders preceding Parkinson's disease: a casecontrol study. Mov Disord 15:669-677
    • (2000) Mov Disord , vol.15 , pp. 669-677
    • Shiba, M.1    Bower, J.H.2    Maraganore, D.M.3
  • 90
    • 84859813166 scopus 로고    scopus 로고
    • Premotor Parkinson's disease: Concepts and definitions
    • Siderowf A, Lang AE (2012) Premotor Parkinson's disease: concepts and definitions. Mov Disord 27:608-616
    • (2012) Mov Disord , vol.27 , pp. 608-616
    • Siderowf, A.1    Lang, A.E.2
  • 91
    • 84858290153 scopus 로고    scopus 로고
    • Impaired olfaction and other prodromal features in the Parkinson at-risk syndrome study
    • Siderowf A, Jennings D, Eberly S et al (2012) Impaired olfaction and other prodromal features in the Parkinson at-risk syndrome study. Mov Disord 27:406-441
    • (2012) Mov Disord , vol.27 , pp. 406-441
    • Siderowf, A.1    Jennings, D.2    Eberly, S.3
  • 92
    • 70350319531 scopus 로고    scopus 로고
    • Multicenter analysis of glucocerebrosidase mutations in Parkinson's disease
    • Sidransky E, Nalls MA, Aasly JO et al (2009) Multicenter analysis of glucocerebrosidase mutations in Parkinson's disease. N Engl J Med 361:1651-1661
    • (2009) N Engl J Med , vol.361 , pp. 1651-1661
    • Sidransky, E.1    Nalls, M.A.2    Aasly, J.O.3
  • 93
    • 84855925916 scopus 로고    scopus 로고
    • Toward a redefinition of Parkinson's disease
    • Stern MB, Lang A, Poewe W (2012) Toward a redefinition of Parkinson's disease. Mov Disord 27:54-60
    • (2012) Mov Disord , vol.27 , pp. 54-60
    • Stern, M.B.1    Lang, A.2    Poewe, W.3
  • 94
    • 11244260421 scopus 로고    scopus 로고
    • Combination of 'idiopathic' REM sleep behaviour disorder and olfactory dysfunction as possible indicator for alpha-synucleinopathy demonstrated by dopamine transporter FP-CIT-SPECT
    • Stiasny-Kolster K, Doerr Y, Möller JC et al (2005) Combination of 'idiopathic' REM sleep behaviour disorder and olfactory dysfunction as possible indicator for alpha-synucleinopathy demonstrated by dopamine transporter FP-CIT-SPECT. Brain 128:126-137
    • (2005) Brain , vol.128 , pp. 126-137
    • Stiasny-Kolster, K.1    Doerr, Y.2    Möller, J.C.3
  • 95
    • 78649990079 scopus 로고    scopus 로고
    • Detection of elevated levels of alpha-synuclein oligomers in CSF from patients with Parkinson disease
    • Tokuda T, Qureshi MM, Ardah MT et al (2010) Detection of elevated levels of alpha-synuclein oligomers in CSF from patients with Parkinson disease. Neurology 75:1766-1772
    • (2010) Neurology , vol.75 , pp. 1766-1772
    • Tokuda, T.1    Qureshi, M.M.2    Ardah, M.T.3
  • 96
    • 77953152279 scopus 로고    scopus 로고
    • Diffusion tensor imaging in idiopathic REM sleep behavior disorder reveals microstructural changes in the brainstem, substantia nigra, olfactory region, and other brain regions
    • Unger MM, Belke M, Menzler K et al (2010) Diffusion tensor imaging in idiopathic REM sleep behavior disorder reveals microstructural changes in the brainstem, substantia nigra, olfactory region, and other brain regions. Sleep 33:767-773
    • (2010) Sleep , vol.33 , pp. 767-773
    • Unger, M.M.1    Belke, M.2    Menzler, K.3
  • 97
    • 67650363783 scopus 로고    scopus 로고
    • Heterozygous carriers of a Parkin or PINK1 mutation share a common functional endophenotype
    • van Nuenen BF, Weiss MM, Bloem BR et al (2009) Heterozygous carriers of a Parkin or PINK1 mutation share a common functional endophenotype. Neurology 72:1041-1047
    • (2009) Neurology , vol.72 , pp. 1041-1047
    • Van Nuenen, B.F.1    Weiss, M.M.2    Bloem, B.R.3
  • 98
    • 1842290405 scopus 로고    scopus 로고
    • Which clinical sign of Parkinson's disease best reflects the nigrostriatal lesion?
    • Vingerhoets FJ, Schulzer M, Calne DB, Snow BJ (1997) Which clinical sign of Parkinson's disease best reflects the nigrostriatal lesion? Ann Neurol 41:58-64
    • (1997) Ann Neurol , vol.41 , pp. 58-64
    • Vingerhoets, F.J.1    Schulzer, M.2    Calne, D.B.3    Snow, B.J.4
  • 99
    • 34447640535 scopus 로고    scopus 로고
    • Parkinson's disease-like midbrain sonography abnormalities are frequent in depressive disorders
    • Walter U, Hoeppner J, Prudente-Morrissey L, Horowski S, Herpertz SC, Benecke R (2007) Parkinson's disease-like midbrain sonography abnormalities are frequent in depressive disorders. Brain 130:1799-1807
    • (2007) Brain , vol.130 , pp. 1799-1807
    • Walter, U.1    Hoeppner, J.2    Prudente-Morrissey, L.3    Horowski, S.4    Herpertz, S.C.5    Benecke, R.6
  • 100
    • 84863164994 scopus 로고    scopus 로고
    • Phosphorylated alphasynuclein in Parkinson's disease
    • Wang Y, Shi M, Chung KA et al (2012) Phosphorylated alphasynuclein in Parkinson's disease. Sci Transl Med 4:121
    • (2012) Sci Transl Med , vol.4 , pp. 121
    • Wang, Y.1    Shi, M.2    Chung, K.A.3
  • 101
    • 79955554760 scopus 로고    scopus 로고
    • Alpha-synuclein reactive antibodies as diagnostic biomarkers in blood sera of Parkinson's disease patients
    • Yanamandra K, Gruden MA, Casaite V, Meskys R, Forsgren L, Morozova-Roche LA (2011) Alpha-synuclein reactive antibodies as diagnostic biomarkers in blood sera of Parkinson's disease patients. PLoS ONE 6:e18513
    • (2011) PLoS ONE , vol.6
    • Yanamandra, K.1    Gruden, M.A.2    Casaite, V.3    Meskys, R.4    Forsgren, L.5    Morozova-Roche, L.A.6


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