A comparative study of the effect of spray drying and hot-melt extrusion on the properties of amorphous solid dispersions containing felodipine

Journal of Pharmacy and Pharmacology

Volumn 66, Issue 2, 2014, Pages 275-284

  Mahmah, Osama ^a   Tabbakh, Rami ^a   Kelly, Adrian ^a   Paradkar, Anant ^a  

^a UNIVERSITY OF BRADFORD   (United Kingdom)

Author keywords

dissolution rate; hot melt extrusion; solid dispersion; spray drying; stability

Indexed keywords

DODECYL SULFATE SODIUM; FELODIPINE; HYDROXYPROPYLMETHYLCELLULOSE ACETATE SUCCINATE; POLYMER; POVIDONE;

ANALYTIC METHOD; ARTICLE; COMPARATIVE STUDY; DIFFERENTIAL SCANNING CALORIMETRY; DISPERSION; DRUG FORMULATION; DRUG RELEASE; DRUG SOLUBILITY; DRUG STABILITY; HOT MELT EXTRUSION; IN VITRO STUDY; PELLET EXTRUSION; SCANNING ELECTRON MICROSCOPY; SPRAY DRYING; THERMAL ANALYSIS; X RAY POWDER DIFFRACTION;

DISSOLUTION RATE; HOT-MELT EXTRUSION; SOLID DISPERSION; SPRAY DRYING; STABILITY;

BIOLOGICAL AVAILABILITY; CHEMISTRY, PHARMACEUTICAL; DESICCATION; DRUG CARRIERS; DRUG COMPOUNDING; DRUG STABILITY; FELODIPINE; HOT TEMPERATURE; HUMANS; METHYLCELLULOSE; POVIDONE; SOLUBILITY; SOLUTIONS; WETTABILITY;

EID: 84892770783     PISSN: 00223573     EISSN: 20427158     Source Type: Journal    
DOI: 10.1111/jphp.12099     Document Type: Article

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