Development of a highly specific and productive process for n-caproic acid production: Applying lessons from methanogenic microbiomes

Water Science and Technology

Volumn 69, Issue 1, 2014, Pages 62-68

  Agler, M T ^a,b   Spirito, C M ^a   Usack, J G ^a   Werner, J J ^a,c   Angenent, L T ^a  

^a Department of Biological and Environmental Engineering   (United States)

^b MAX PLANCK INSTITUTE FOR PLANT BREEDING RESEARCH   (Germany)

^c STATE UNIVERSITY OF NEW YORK   (United States)

Author keywords

Liquid biochemical; Mixed culture; n caproic acid; n hexanoic acid; Reactor microbiome

Indexed keywords

ANAEROBIC DIGESTER; CHAIN ELONGATION; HIGH PRODUCTIVITY; MICROBIOME; MIXED CULTURES; PRODUCT RECOVERY; PRODUCTIVE PROCESS; SHORT-CHAIN CARBOXYLIC ACIDS;

ANAEROBIC DIGESTION; CARBON; CARBOXYLIC ACIDS; CHAINS; ETHANOL; LIQUIDS; METHANE;

SATURATED FATTY ACIDS;

ALCOHOL; CARBOXYLIC ACID; HEXANOIC ACID; METHANE;

ANOXIC CONDITIONS; BACTERIUM; CARBOXYLIC ACID; CATALYSIS; ETHANOL; INHIBITION; METHANE; METHANOGENESIS; MICROBIOLOGY; SOLID WASTE; SOLUBILITY; WASTE TREATMENT;

ANAEROBIC DIGESTION; ARTICLE; CATALYSIS; METHANOGENESIS; METHANOGENIC BACTERIUM; MICROBIOME; NONHUMAN; PH; REACTOR; SEQUENCING BATCH REACTOR; SOLID WASTE MANAGEMENT; SOLUBILITY;

ANAEROBIOSIS; BIOREACTORS; CAPROATES; REFUSE DISPOSAL;

EID: 84892770126     PISSN: 02731223     EISSN: None     Source Type: Journal    
DOI: 10.2166/wst.2013.549     Document Type: Article

References (15)

1. Agler, M. T., Aydinkaya, Z., Cummings, T. A., Beers, A. R. & Angenent, L. T. 2010 Anaerobic digestion of brewery primary sludge to enhance bioenergy generation: A comparison between low- and high-rate solids treatment and different temperatures. Bioresource Technology 101 (15), 5842-5851.
2. Agler, M. T., Werner, J. J., Iten, L. B., Dekker, A., Cotta, M. A., Dien, B. S. & Angenent, L. T. 2012a Shaping reactor microbiomes to produce the fuel precursor n-butyrate from pretreated cellulosic hydrolysates. Environmental Science and Technology 46 (18), 10229-10238.
3. Agler, M. T., Spirito, C. M., Usack, J. G., Werner, J. J. & Angenent, L. T. 2012b Chain elongation with reactor microbiomes: upgrading dilute ethanol to medium-chain carboxylates. Energy and Environmental Science 5 (8), 8189-8192.
4. Agler, M. T., Wrenn, B. A., Zinder, S. H. & Angenent, L. T. 2011 Waste to bioproduct conversion with undefined mixed cultures: the carboxylate platform. Trends in Biotechnology 29 (2), 70-78.
5. Butkus, M. A., Hughes, K. T., Bowman, D. D., Liotta, J. L., Jenkins, M. B. & Labare, M. P. 2011 Inactivation of Ascaris suum by short-chain fatty acids. Applied and Environmental Microbiology 77 (1), 363-366.
6. Canganella, F., Kuk, S.-U., Morgan, H. & Wiegel, J. 2002 Clostridium thermobutyricum growth studies and stimulation of butyrate formation by acetate supplementation. Microbiological Research 157 (2), 149-156.
7. Herrero, A. A., Gomez, R. F., Snedecor, B., Tolman, C. J. & Roberts, M. F. 1985 Growth inhibition of Clostridium thermocellum by carboxylic acids: a mechanism based on uncoupling by weak acids. Applied Microbiology and Biotechnology 22 (1), 53-62.
8. Kleerebezem, R. & van Loosdrecht, M. C. M. 2007 Mixed culture biotechnology for bioenergy production. Current Opinion in Biotechnology 18 (3), 207-212.
9. Rodriguez, J., Kleerebezem, R., Lema, J. & van Loosdrecht, M. 2006 Modeling product formation in anaerobic mixed culture fermentations. Biotechnology and Bioengineering 93 (3), 592-606.
10. Seedorf, H., Fricke, W. F., Veith, B., Bruggemann, H., Liesegang, H., Strittmatter, A., Miethke, M., Buckel, W., Hinderberger, J., Li, F., Hagemeier, C., Thauer, R. K. & Gottschalk, G. 2008 The genome of Clostridium kluyveri, a strict anaerobe with unique metabolic features. Proceedings of the National Academy of Sciences of the United States of America 105 (6), 2128-2133.
11. Steinbusch, K. J. J., Hamelers, H. V. M., Plugge, C. M. & Buisman, C. J. N. 2011 Biological formation of caproate and caprylate from acetate: fuel and chemical production from low grade biomass. Energy and Environmental Science 4 (1), 216-224.
12. Werner, J. J., Knights, D., Garcia, M. L., Scalfone, N. B., Smith, S., Yarasheski, K., Cummings, T. A., Beers, A. R., Knight, R. & Angenent, L. T. 2011 Bacterial community structures are unique and resilient in full-scale bioenergy systems. Proceedings of the National Academy of Sciences of the United States of America 108 (10), 4158-4163.
13. Wirth, R., Kovács, E., Maróti, G., Bagi, Z., Rákhely, G. & Kovács, K. 2012 Characterization of a biogas-producing microbial community by short-read next generation DNA sequencing. Biotechnology for Biofuels 5 (1), 1-16.
14. Wu, Z. & Yang, S.-T. 2003 Extractive fermentation for butyric acid production from glucose by Clostridium tyrobutyricum. Biotechnology and Bioengineering 82 (1), 93-102.
15. Zinder, S. H., Anguish, T. & Cardwell, S. C. 1984 Selective inhibition by 2-bromoethanesulfonate of methanogenesis from acetate in a thermophilic anaerobic digestor. Applied and Environmental Microbiology 47 (6), 1343-1345.