Progranulin, a major secreted protein of mouse adipose-derived stem cells, inhibits light-induced retinal degeneration

Stem Cells Translational Medicine

Volumn 3, Issue 1, 2014, Pages 42-53

  Tsuruma, Kazuhiro ^a   Yamauchi, Mika ^a   Sugitani, Sou ^a   Otsuka, Tomohiro ^a   Ohno, Yuta ^a   Nagahara, Yuki ^a   Ikegame, Yuka ^b   Shimazawa, Masamitsu ^a   Yoshimura, Shinichi ^b   Iwama, Toru ^b   Hara, Hideaki ^a  

^a GIFU PHARMACEUTICAL UNIVERSITY   (Japan)

^b GIFU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Adipose derived stem cell; Light induced photoreceptor cell death; Photoreceptor; Progranulin; Retina

Indexed keywords

CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; PROGRANULIN; PROTEIN KINASE C; SCATTER FACTOR RECEPTOR;

ADIPOCYTE; ADIPOSE DERIVED STEM CELL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ELECTRORETINOGRAPHY; HISTOLOGY; IMMUNOHISTOCHEMISTRY; LIGHT EXPOSURE; MALE; MOUSE; NEUROPROTECTION; NONHUMAN; PHOTORECEPTOR CELL; PROTEIN EXPRESSION; PROTEIN MICROARRAY; PROTEIN PHOSPHORYLATION; RETINA DEGENERATION; VISUAL STIMULATION; WESTERN BLOTTING;

ADIPOSE-DERIVED STEM CELL; LIGHT-INDUCED PHOTORECEPTOR CELL DEATH; PHOTORECEPTOR; PROGRANULIN; RETINA;

ADIPOSE TISSUE; ANIMALS; ANIMALS, OUTBRED STRAINS; CELL CULTURE TECHNIQUES; CELL DEATH; CULTURE MEDIA, CONDITIONED; CYTOKINES; HYDROGEN PEROXIDE; INJECTIONS, INTRAOCULAR; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; LIGHT; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; OXIDANTS; PHOTORECEPTOR CELLS, VERTEBRATE; PROTEIN KINASE C; RETINAL DEGENERATION; STEM CELL TRANSPLANTATION; STEM CELLS;

EID: 84892758291     PISSN: 21576564     EISSN: 21576580     Source Type: Journal    
DOI: 10.5966/sctm.2013-0020     Document Type: Article

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