Demonstrating enhanced throughput of RapidFire mass spectrometry through multiplexing using the JmjD2d demethylase as a Model System

Journal of Biomolecular Screening

Volumn 19, Issue 2, 2014, Pages 278-286

  Leveridge, Melanie ^a   Buxton, Rachel ^a   Argyrou, Argyrides ^a   Francis, Peter ^a   Leavens, Bill ^a   West, Andy ^a   Rees, Mike ^a   Hardwicke, Philip ^a   Bridges, Angela ^a   Ratcliffe, Steven ^a   Chung, Chun Wa ^a  

^a GLAXOSMITHKLINE   (United Kingdom)

Author keywords

epigenetics; high throughput screen; histone demethylase; Jumonji enzymes; mass spectrometry; multiplexing; RapidFire

Indexed keywords

HISTONE DEMETHYLASE; HISTONE DEMETHYLASE JMJD2D; HISTONE H3; UNCLASSIFIED DRUG;

ARTICLE; AUTOMATION; CONTROLLED STUDY; ENZYME ACTIVITY; FLUORESCENCE; HIGH THROUGHPUT SCREENING; MASS SPECTROMETER; MASS SPECTROMETRY; MODEL; PRIORITY JOURNAL;

EPIGENETICS; HIGH-THROUGHPUT SCREEN; HISTONE DEMETHYLASE; JUMONJI ENZYMES; MASS SPECTROMETRY; MULTIPLEXING; RAPIDFIRE;

EPIGENOMICS; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; JUMONJI DOMAIN-CONTAINING HISTONE DEMETHYLASES; MASS SPECTROMETRY; SUBSTRATE SPECIFICITY;

EID: 84892755133     PISSN: 10870571     EISSN: 1552454X     Source Type: Journal    
DOI: 10.1177/1087057113496276     Document Type: Article

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