메뉴 건너뛰기




Volumn 11, Issue , 2014, Pages

Protection of ischemic post conditioning against transient focal ischemia-induced brain damage is associated with inhibition of neuroinflammation via modulation of TLR2 and TLR4 pathways

Author keywords

Cerebral ischemia reperfusion; Ischemic postconditioning; Neuroinflammation; TLR2; TLR4

Indexed keywords

INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 4; INTERLEUKIN 1BETA; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4;

EID: 84892738438     PISSN: None     EISSN: 17422094     Source Type: Journal    
DOI: 10.1186/1742-2094-11-15     Document Type: Article
Times cited : (50)

References (37)
  • 1
    • 70350103848 scopus 로고    scopus 로고
    • Neuroendovascular management of acute ischemic stroke
    • 10.1016/j.nec.2009.07.005, 19853801
    • Tjoumakaris SI, Jabbour PM, Rosenwasser RH. Neuroendovascular management of acute ischemic stroke. Neurosurg Clin N Am 2009, 20:419-429. 10.1016/j.nec.2009.07.005, 19853801.
    • (2009) Neurosurg Clin N Am , vol.20 , pp. 419-429
    • Tjoumakaris, S.I.1    Jabbour, P.M.2    Rosenwasser, R.H.3
  • 2
    • 33747603205 scopus 로고    scopus 로고
    • Interrupting reperfusion as a stroke therapy: ischemic postconditioning reduces infarct size after focal ischemia in rats
    • Zhao H, Sapolsky RM, Steinberg GK. Interrupting reperfusion as a stroke therapy: ischemic postconditioning reduces infarct size after focal ischemia in rats. J Cereb Blood Flow Metab 2006, 26:1114-1121.
    • (2006) J Cereb Blood Flow Metab , vol.26 , pp. 1114-1121
    • Zhao, H.1    Sapolsky, R.M.2    Steinberg, G.K.3
  • 4
    • 84856437129 scopus 로고    scopus 로고
    • Ischemic postconditioning protects liver from ischemia-reperfusion injury by modulating mitochondrial permeability transition
    • 10.1097/TP.0b013e31823ef335, 22198494
    • Lin HC, Lee TK, Tsai CC, Lai IR, Lu KS. Ischemic postconditioning protects liver from ischemia-reperfusion injury by modulating mitochondrial permeability transition. Transplantation 2012, 93:265-271. 10.1097/TP.0b013e31823ef335, 22198494.
    • (2012) Transplantation , vol.93 , pp. 265-271
    • Lin, H.C.1    Lee, T.K.2    Tsai, C.C.3    Lai, I.R.4    Lu, K.S.5
  • 5
    • 67349254659 scopus 로고    scopus 로고
    • Immediate postconditioning during reperfusion attenuates intestinal injury
    • 10.1007/s00134-009-1428-1, 19190893
    • Liu KX, Li YS, Huang WQ, Chen SQ, Wang ZX, Liu JX, Xia Z. Immediate postconditioning during reperfusion attenuates intestinal injury. Intensive Care Med 2009, 35:933-942. 10.1007/s00134-009-1428-1, 19190893.
    • (2009) Intensive Care Med , vol.35 , pp. 933-942
    • Liu, K.X.1    Li, Y.S.2    Huang, W.Q.3    Chen, S.Q.4    Wang, Z.X.5    Liu, J.X.6    Xia, Z.7
  • 6
    • 41249084455 scopus 로고    scopus 로고
    • Ischemic postconditioning protects against global cerebral ischemia/reperfusion-induced injury in rats
    • 10.1161/STROKEAHA.107.499079, 18239163
    • Wang JY, Shen J, Gao Q, Ye ZG, Yang SY, Liang HW, Bruce IC, Luo BY, Xia Q. Ischemic postconditioning protects against global cerebral ischemia/reperfusion-induced injury in rats. Stroke 2008, 39:983-990. 10.1161/STROKEAHA.107.499079, 18239163.
    • (2008) Stroke , vol.39 , pp. 983-990
    • Wang, J.Y.1    Shen, J.2    Gao, Q.3    Ye, Z.G.4    Yang, S.Y.5    Liang, H.W.6    Bruce, I.C.7    Luo, B.Y.8    Xia, Q.9
  • 7
    • 57549115569 scopus 로고    scopus 로고
    • Delayed postconditioning protects against focal ischemic brain injury in rats
    • 10.1371/journal.pone.0003851, 2588536, 19066627
    • Ren C, Gao X, Niu G, Yan Z, Chen X, Zhao H. Delayed postconditioning protects against focal ischemic brain injury in rats. PLoS One 2008, 3:e3851. 10.1371/journal.pone.0003851, 2588536, 19066627.
    • (2008) PLoS One , vol.3
    • Ren, C.1    Gao, X.2    Niu, G.3    Yan, Z.4    Chen, X.5    Zhao, H.6
  • 8
    • 84880161619 scopus 로고    scopus 로고
    • TLR2 and TLR4 in the brain injury caused by cerebral ischemia and reperfusion
    • 3706022, 23864765
    • Wang Y, Ge P, Zhu Y. TLR2 and TLR4 in the brain injury caused by cerebral ischemia and reperfusion. Mediators Inflamm 2013, 2013:124614. 3706022, 23864765.
    • (2013) Mediators Inflamm , vol.2013 , pp. 124614
    • Wang, Y.1    Ge, P.2    Zhu, Y.3
  • 9
    • 79956193593 scopus 로고    scopus 로고
    • Comparison of cardioprotective and anti-inflammatory effects of ischemia pre- and postconditioning in rats with myocardial ischemia-reperfusion injury
    • 10.1007/s00011-010-0303-4, 21193944
    • Xiong J, Wang Q, Xue FS, Yuan YJ, Li S, Liu JH, Liao X, Zhang YM. Comparison of cardioprotective and anti-inflammatory effects of ischemia pre- and postconditioning in rats with myocardial ischemia-reperfusion injury. Inflamm Res 2011, 60:547-554. 10.1007/s00011-010-0303-4, 21193944.
    • (2011) Inflamm Res , vol.60 , pp. 547-554
    • Xiong, J.1    Wang, Q.2    Xue, F.S.3    Yuan, Y.J.4    Li, S.5    Liu, J.H.6    Liao, X.7    Zhang, Y.M.8
  • 11
    • 84875489498 scopus 로고    scopus 로고
    • Absence of TLR4 reduces neurovascular unit and secondary inflammatory process after traumatic brain injury in mice
    • 10.1371/journal.pone.0057208, 3610903, 23555560
    • Ahmad A, Crupi R, Campolo M, Genovese T, Esposito E, Cuzzocrea S. Absence of TLR4 reduces neurovascular unit and secondary inflammatory process after traumatic brain injury in mice. PLoS One 2013, 8:e57208. 10.1371/journal.pone.0057208, 3610903, 23555560.
    • (2013) PLoS One , vol.8
    • Ahmad, A.1    Crupi, R.2    Campolo, M.3    Genovese, T.4    Esposito, E.5    Cuzzocrea, S.6
  • 12
    • 84877823003 scopus 로고    scopus 로고
    • Ischemic postconditioning protects against focal cerebral ischemia by inhibiting brain inflammation while attenuating peripheral lymphopenia in mice
    • Joo SP, Xie W, Xiong X, Xu B, Zhao H. Ischemic postconditioning protects against focal cerebral ischemia by inhibiting brain inflammation while attenuating peripheral lymphopenia in mice. Neuroscience 2013, 243:149-157.
    • (2013) Neuroscience , vol.243 , pp. 149-157
    • Joo, S.P.1    Xie, W.2    Xiong, X.3    Xu, B.4    Zhao, H.5
  • 13
    • 84876408681 scopus 로고    scopus 로고
    • Ischemic postconditioning downregulates Egr-1 expression and attenuates postischemic pulmonary inflammatory cytokine release and tissue injury in rats
    • 10.1016/j.jss.2012.07.031, 22878149
    • Wu H, Lei S, Yuan J, Liu X, Zhang D, Gu X, Zhang L, Xia Z. Ischemic postconditioning downregulates Egr-1 expression and attenuates postischemic pulmonary inflammatory cytokine release and tissue injury in rats. J Surg Res 2013, 181:204-212. 10.1016/j.jss.2012.07.031, 22878149.
    • (2013) J Surg Res , vol.181 , pp. 204-212
    • Wu, H.1    Lei, S.2    Yuan, J.3    Liu, X.4    Zhang, D.5    Gu, X.6    Zhang, L.7    Xia, Z.8
  • 14
    • 80054985592 scopus 로고    scopus 로고
    • Ischemic postconditioning attenuates liver warm ischemia-reperfusion injury through Akt-eNOS-NO-HIF pathway
    • 10.1186/1423-0127-18-79, 3212808, 22035453
    • Guo JY, Yang T, Sun XG, Zhou NY, Li FS, Long D, Lin T, Li PY, Feng L. Ischemic postconditioning attenuates liver warm ischemia-reperfusion injury through Akt-eNOS-NO-HIF pathway. J Biomed Sci 2011, 18:79. 10.1186/1423-0127-18-79, 3212808, 22035453.
    • (2011) J Biomed Sci , vol.18 , pp. 79
    • Guo, J.Y.1    Yang, T.2    Sun, X.G.3    Zhou, N.Y.4    Li, F.S.5    Long, D.6    Lin, T.7    Li, P.Y.8    Feng, L.9
  • 15
    • 84876177190 scopus 로고    scopus 로고
    • Effective neuroprotection by ischemic postconditioning is associated with a decreased expression of RGMa and inflammation mediators in ischemic rats
    • 10.1007/s11064-013-0984-5, 23389659
    • Kong Y, Rogers MR, Qin X. Effective neuroprotection by ischemic postconditioning is associated with a decreased expression of RGMa and inflammation mediators in ischemic rats. Neurochem Res 2013, 38:815-825. 10.1007/s11064-013-0984-5, 23389659.
    • (2013) Neurochem Res , vol.38 , pp. 815-825
    • Kong, Y.1    Rogers, M.R.2    Qin, X.3
  • 16
    • 0027519254 scopus 로고
    • Effect of brain edema on infarct volume in a focal cerebral ischemia model in rats
    • 10.1161/01.STR.24.1.117, 8418534
    • Lin TN, He YY, Wu G. Effect of brain edema on infarct volume in a focal cerebral ischemia model in rats. Stroke 1993, 24:117-121. 10.1161/01.STR.24.1.117, 8418534.
    • (1993) Stroke , vol.24 , pp. 117-121
    • Lin, T.N.1    He, Y.Y.2    Wu, G.3
  • 17
    • 0029839695 scopus 로고    scopus 로고
    • Middle cerebral artery occlusion in the rat by intraluminal suture. Neurological and pathological evaluation of an improved model
    • 10.1161/01.STR.27.9.1616, 8784138
    • Belayev L, Alonso OF, Busto R, Zhao W, Ginsberg MD. Middle cerebral artery occlusion in the rat by intraluminal suture. Neurological and pathological evaluation of an improved model. Stroke 1996, 27:1616-1623. 10.1161/01.STR.27.9.1616, 8784138.
    • (1996) Stroke , vol.27 , pp. 1616-1623
    • Belayev, L.1    Alonso, O.F.2    Busto, R.3    Zhao, W.4    Ginsberg, M.D.5
  • 18
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method
    • 10.1006/meth.2001.1262, 11846609
    • Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 2001, 25:402-408. 10.1006/meth.2001.1262, 11846609.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 19
    • 49349106431 scopus 로고    scopus 로고
    • Protective effects of ischemic postconditioning compared with gradual reperfusion or preconditioning
    • 10.1002/jnr.21703, 18438944
    • Gao X, Ren C, Zhao H. Protective effects of ischemic postconditioning compared with gradual reperfusion or preconditioning. J Neurosci Res 2008, 86:2505-2511. 10.1002/jnr.21703, 18438944.
    • (2008) J Neurosci Res , vol.86 , pp. 2505-2511
    • Gao, X.1    Ren, C.2    Zhao, H.3
  • 20
    • 84875112049 scopus 로고    scopus 로고
    • Expression analysis of genes involved in TLR2-related signaling pathway: inflammation and apoptosis after ischemic brain injury
    • Winters L, Winters T, Gorup D, Mitrečić D, Curlin M, Križ J, Gajović S. Expression analysis of genes involved in TLR2-related signaling pathway: inflammation and apoptosis after ischemic brain injury. Neuroscience 2013, 238:87-96.
    • (2013) Neuroscience , vol.238 , pp. 87-96
    • Winters, L.1    Winters, T.2    Gorup, D.3    Mitrečić, D.4    Curlin, M.5    Križ, J.6    Gajović, S.7
  • 21
    • 80054891680 scopus 로고    scopus 로고
    • Ginkgolide B reduces neuronal cell apoptosis in the hemorrhagic rat brain: possible involvement of Toll-like receptor 4/nuclear factor-kappa B pathway
    • 10.1016/j.jep.2011.08.034, 21878382
    • Hu YY, Huang M, Dong XQ, Xu QP, Yu WH, Zhang ZY. Ginkgolide B reduces neuronal cell apoptosis in the hemorrhagic rat brain: possible involvement of Toll-like receptor 4/nuclear factor-kappa B pathway. J Ethnopharmacol 2011, 137:1462-1468. 10.1016/j.jep.2011.08.034, 21878382.
    • (2011) J Ethnopharmacol , vol.137 , pp. 1462-1468
    • Hu, Y.Y.1    Huang, M.2    Dong, X.Q.3    Xu, Q.P.4    Yu, W.H.5    Zhang, Z.Y.6
  • 22
    • 70350129230 scopus 로고    scopus 로고
    • IRAK-4 inhibitors for inflammation
    • 10.2174/156802609789044407, 3182414, 19689377
    • Wang Z, Wesche H, Stevens T, Walker N, Yeh WC. IRAK-4 inhibitors for inflammation. Curr Top Med Chem 2009, 9:724-737. 10.2174/156802609789044407, 3182414, 19689377.
    • (2009) Curr Top Med Chem , vol.9 , pp. 724-737
    • Wang, Z.1    Wesche, H.2    Stevens, T.3    Walker, N.4    Yeh, W.C.5
  • 23
    • 79960101157 scopus 로고    scopus 로고
    • How to make better use of thrombolytic therapy in acute ischemic stroke
    • 10.1038/nrneurol.2011.89, 21670766
    • Donnan GA, Davis SM, Parsons MW, Ma H, Dewey HM, Howells DW. How to make better use of thrombolytic therapy in acute ischemic stroke. Nat Rev Neurol 2011, 7:400-409. 10.1038/nrneurol.2011.89, 21670766.
    • (2011) Nat Rev Neurol , vol.7 , pp. 400-409
    • Donnan, G.A.1    Davis, S.M.2    Parsons, M.W.3    Ma, H.4    Dewey, H.M.5    Howells, D.W.6
  • 24
    • 33645080694 scopus 로고    scopus 로고
    • Postconditioning protects against endothelial ischemia-reperfusion injury in the human forearm
    • 10.1161/CIRCULATIONAHA.105.590398, 16476844
    • Loukogeorgakis SP, Panagiotidou AT, Yellon DM, Deanfield JE, MacAllister RJ. Postconditioning protects against endothelial ischemia-reperfusion injury in the human forearm. Circulation 2006, 113:1015-1019. 10.1161/CIRCULATIONAHA.105.590398, 16476844.
    • (2006) Circulation , vol.113 , pp. 1015-1019
    • Loukogeorgakis, S.P.1    Panagiotidou, A.T.2    Yellon, D.M.3    Deanfield, J.E.4    MacAllister, R.J.5
  • 25
    • 84874626831 scopus 로고    scopus 로고
    • Ischemic postconditioning may increase serum fetuin-A level in patients with acute ST-segment elevation myocardial infarction undergoing percutaneous intervention
    • Liu SH, Huo YE, Yin BY, Li XH, Wang YF. Ischemic postconditioning may increase serum fetuin-A level in patients with acute ST-segment elevation myocardial infarction undergoing percutaneous intervention. Clin Lab 2013, 59:59-64.
    • (2013) Clin Lab , vol.59 , pp. 59-64
    • Liu, S.H.1    Huo, Y.E.2    Yin, B.Y.3    Li, X.H.4    Wang, Y.F.5
  • 26
    • 84874566825 scopus 로고    scopus 로고
    • Ischemic postconditioning decreases cerebral edema and brain blood barrier disruption caused by relief of carotid stenosis in a rat model of cerebral hypoperfusion
    • 10.1371/journal.pone.0057869, 3585273, 23469092
    • Yang F, Zhang X, Sun Y, Wang B, Zhou C, Luo Y, Ge P. Ischemic postconditioning decreases cerebral edema and brain blood barrier disruption caused by relief of carotid stenosis in a rat model of cerebral hypoperfusion. PLoS One 2013, 8:e57869. 10.1371/journal.pone.0057869, 3585273, 23469092.
    • (2013) PLoS One , vol.8
    • Yang, F.1    Zhang, X.2    Sun, Y.3    Wang, B.4    Zhou, C.5    Luo, Y.6    Ge, P.7
  • 27
    • 79953027116 scopus 로고    scopus 로고
    • Toll-like receptor 4 is involved in ischemic tolerance of postconditioning in hippocampus of tree shrews to thrombotic cerebral ischemia
    • Feng R, Li S, Li F. Toll-like receptor 4 is involved in ischemic tolerance of postconditioning in hippocampus of tree shrews to thrombotic cerebral ischemia. Brain Res 2011, 1384:118-227.
    • (2011) Brain Res , vol.1384 , pp. 118-227
    • Feng, R.1    Li, S.2    Li, F.3
  • 28
    • 84866992233 scopus 로고    scopus 로고
    • Inhibition of autophagy contributes to ischemic postconditioning-induced neuroprotection against focal cerebral ischemia in rats
    • 10.1371/journal.pone.0046092, 3461004, 23029398
    • Gao L, Jiang T, Guo J, Liu Y, Cui G, Gu L, Su L, Zhang Y. Inhibition of autophagy contributes to ischemic postconditioning-induced neuroprotection against focal cerebral ischemia in rats. PLoS One 2012, 7:e46092. 10.1371/journal.pone.0046092, 3461004, 23029398.
    • (2012) PLoS One , vol.7
    • Gao, L.1    Jiang, T.2    Guo, J.3    Liu, Y.4    Cui, G.5    Gu, L.6    Su, L.7    Zhang, Y.8
  • 29
    • 78650511500 scopus 로고    scopus 로고
    • Ischemic postconditioning protects brain from ischemia/reperfusion injury by attenuating endoplasmic reticulum stress-induced apoptosis through PI3K-Akt pathway
    • Yuan Y, Guo Q, Ye Z, Pingping X, Wang N, Song Z. Ischemic postconditioning protects brain from ischemia/reperfusion injury by attenuating endoplasmic reticulum stress-induced apoptosis through PI3K-Akt pathway. Brain Res 2011, 1367:85-93.
    • (2011) Brain Res , vol.1367 , pp. 85-93
    • Yuan, Y.1    Guo, Q.2    Ye, Z.3    Pingping, X.4    Wang, N.5    Song, Z.6
  • 30
    • 33845548578 scopus 로고    scopus 로고
    • The changes in endogenous antioxidant enzyme activity after postconditioning
    • Danielisová V, Némethová M, Gottlieb M, Burda J. The changes in endogenous antioxidant enzyme activity after postconditioning. Cell Mol Neurobiol 2006, 26:1181-1191.
    • (2006) Cell Mol Neurobiol , vol.26 , pp. 1181-1191
    • Danielisová, V.1    Némethová, M.2    Gottlieb, M.3    Burda, J.4
  • 31
    • 38549149924 scopus 로고    scopus 로고
    • In vivo and in vitro characterization of a novel neuroprotective strategy for stroke: ischemic postconditioning
    • 10.1038/sj.jcbfm.9600559, 17882162
    • Pignataro G, Meller R, Inoue K, Ordonez AN, Ashley MD, Xiong Z, Gala R, Simon RP. In vivo and in vitro characterization of a novel neuroprotective strategy for stroke: ischemic postconditioning. J Cereb Blood Flow Metab 2008, 28:232-241. 10.1038/sj.jcbfm.9600559, 17882162.
    • (2008) J Cereb Blood Flow Metab , vol.28 , pp. 232-241
    • Pignataro, G.1    Meller, R.2    Inoue, K.3    Ordonez, A.N.4    Ashley, M.D.5    Xiong, Z.6    Gala, R.7    Simon, R.P.8
  • 32
    • 0034528154 scopus 로고    scopus 로고
    • Inflammation marker 7,8-dihydroneopterin induces apoptosis of neurons and glial cells: a potential contribution to neurodegenerative processes
    • 10.1016/S0171-2985(00)80104-7, 11205375
    • Speth C, Stöckl G, Fuchs D, Wirleitner B, Widner B, Würzner R, Mohsenipour I, Lass-Flörl C, Dierich MP. Inflammation marker 7,8-dihydroneopterin induces apoptosis of neurons and glial cells: a potential contribution to neurodegenerative processes. Immunobiology 2000, 202:460-476. 10.1016/S0171-2985(00)80104-7, 11205375.
    • (2000) Immunobiology , vol.202 , pp. 460-476
    • Speth, C.1    Stöckl, G.2    Fuchs, D.3    Wirleitner, B.4    Widner, B.5    Würzner, R.6    Mohsenipour, I.7    Lass-Flörl, C.8    Dierich, M.P.9
  • 33
    • 84864592986 scopus 로고    scopus 로고
    • Ischemic postconditioning inhibits the renal fibrosis induced by ischemia-reperfusion injury in rats
    • Weng X, Shen H, Kuang Y, Liu X, Chen Z, Zhu H, Jiang B, Zhu G, Chen H. Ischemic postconditioning inhibits the renal fibrosis induced by ischemia-reperfusion injury in rats. Urology 2012, 80:484.e1-484.e7.
    • (2012) Urology , vol.80
    • Weng, X.1    Shen, H.2    Kuang, Y.3    Liu, X.4    Chen, Z.5    Zhu, H.6    Jiang, B.7    Zhu, G.8    Chen, H.9
  • 34
    • 61349152312 scopus 로고    scopus 로고
    • Inhibition of the inflammasome complex reduces the inflammatory response after thromboembolic stroke in mice
    • 10.1038/jcbfm.2008.143, 19066616
    • Abulafia DP, de Rivero Vaccari JP, Lozano JD, Lotocki G, Keane RW, Dietrich WD. Inhibition of the inflammasome complex reduces the inflammatory response after thromboembolic stroke in mice. J Cereb Blood Flow Metab 2009, 29:534-544. 10.1038/jcbfm.2008.143, 19066616.
    • (2009) J Cereb Blood Flow Metab , vol.29 , pp. 534-544
    • Abulafia, D.P.1    de Rivero Vaccari, J.P.2    Lozano, J.D.3    Lotocki, G.4    Keane, R.W.5    Dietrich, W.D.6
  • 36
    • 79551633839 scopus 로고    scopus 로고
    • Blocking TLR2 in vivo protects against accumulation of inflammatory cells and neuronal injury in experimental stroke
    • 10.1038/jcbfm.2010.161, 3049529, 20842165
    • Ziegler G, Freyer D, Harhausen D, Khojasteh U, Nietfeld W, Trendelenburg G. Blocking TLR2 in vivo protects against accumulation of inflammatory cells and neuronal injury in experimental stroke. J Cereb Blood Flow Metab 2011, 31:757-766. 10.1038/jcbfm.2010.161, 3049529, 20842165.
    • (2011) J Cereb Blood Flow Metab , vol.31 , pp. 757-766
    • Ziegler, G.1    Freyer, D.2    Harhausen, D.3    Khojasteh, U.4    Nietfeld, W.5    Trendelenburg, G.6
  • 37
    • 84873242419 scopus 로고    scopus 로고
    • Toll-like receptor 4 mediates microglial activation and production of inflammatory mediators in neonatal rat brain following hypoxia: role of TLR4 in hypoxic microglia
    • 10.1186/1742-2094-10-23, 3575244, 23388509
    • Yao L, Kan EM, Lu J, Hao A, Dheen ST, Kaur C, Ling EA. Toll-like receptor 4 mediates microglial activation and production of inflammatory mediators in neonatal rat brain following hypoxia: role of TLR4 in hypoxic microglia. J Neuroinflammation 2013, 10:23. 10.1186/1742-2094-10-23, 3575244, 23388509.
    • (2013) J Neuroinflammation , vol.10 , pp. 23
    • Yao, L.1    Kan, E.M.2    Lu, J.3    Hao, A.4    Dheen, S.T.5    Kaur, C.6    Ling, E.A.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.