Comparative analysis of antioxidants against cadmium induced reproductive toxicity in adult male rats

Systems Biology in Reproductive Medicine

Volumn 60, Issue 1, 2014, Pages 28-34

  Jahan, Sarwat ^a   Khan, Mehreen ^a   Ahmed, Shakeel ^a   Ullah, Hizb ^a  

^a QUAID I AZAM UNIVERSITY   (Pakistan)

Author keywords

Antioxidants; Ficus religiosa; Reproductive toxicity; Sulforaphane

Indexed keywords

ALPHA TOCOPHEROL; ANTIOXIDANT; CADMIUM; PLANT EXTRACT; SULFORAPHANE; TESTOSTERONE; ZINC;

ADULT; ANIMAL TISSUE; ARTICLE; BLOOD SAMPLING; BODY WEIGHT; CONTROLLED STUDY; FICUS RELIGIOSA; MALE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; REPRODUCTIVE TOXICITY; SPERMATOGENESIS; TESTIS; TESTOSTERONE BLOOD LEVEL; ZINC BLOOD LEVEL;

ANIMALS; ANTIOXIDANTS; BODY WEIGHT; CADMIUM; CASE-CONTROL STUDIES; ISOTHIOCYANATES; MALE; PLANT EXTRACTS; RATS; RATS, SPRAGUE-DAWLEY; REPRODUCTION; SPERMATOGENESIS; TESTIS; TESTOSTERONE; VITAMIN E; ZINC;

EID: 84892735355     PISSN: 19396368     EISSN: 19396376     Source Type: Journal    
DOI: 10.3109/19396368.2013.843039     Document Type: Article

References (45)

1. Adikpoh, M.A. and Obi, F.O. (2009) Prevention of cadmium induced alteration in rat testes and prostate lipid pattern by alpha tocopherol. Afric J of Biochem Res 3: 321-325.
2. Afolabi, A.O., Olotu, O.O. and Abdullateef, I. (2012) Vitamins E and C Alleviate the Germ Cell Loss and Oxidative Stress in Cryptorchidism When Administered Separately but Not When Combined in Rats. ISRN Pharmacol Article I.D 843569.
3. Agarwal, A. and Saleh, R.A. (2002) Role of oxidants in male infertility: rationale, significance and treatment. Urol Clin North Am 29: 817-827.
4. Aitkon, R.J. and Clarkson, J.S. (1987) Cellular basis of defective sperm function and its association with the genesis of reactive oxygen species by human spermatozoa. J Reprod Fertil 81: 459-469.
5. Amara, S., Abdelmelek, H., Garrel, C., Guiraud, P., Douki, T., Ravanat, J.L., et al. (2008) Preventive effect of zinc against cadmium-induced oxidative stress in the rat testis. J Reprod Dev 54: 129-134.
6. Azzi, A., Boscoboinik, D., Chatelain, E., Ozer, N.K and Stauble B. (1993) d-a-tocopherol control of cell proliferation. Mol Asp Med 14: 265-271.
7. Bench, G., Corzett, M.H., Martinelli, R. and Balhorn, R. (1999) Cadmium concentrations in the testes, sperm and spermatids of mice subjected to long-term Cadmium chloride exposure. Cytomet 35: 30-36.
8. Benoff, S., Jacob, A. and Hurley, I.R. (2000) Male infertility and environmental exposure to lead and cadmium. Hum Reprod 6: 107-121.
9. Bonda, E., Wlostowski, T. and Krasowska, A. (2004) Testicular toxicity induced by dietary cadmium is associated with decreased testicular zinc and increased hepatic and renal metallothionein and zinc in the bank vole. Biometals 17: 615-624.
10. Burukoglu, D. and Baycu, C. (2008) Protective effects of zinc on testes of cadmium-treated rats. Bull Environ Contam Toxicol 81: 521-524.
11. Cho, E.J., Lee, Y.A., Yoo, H.H. and Yokozawa, T. (2006) Protective effect of broccoli (brassica oleracea) against oxidative damage in vitro and in vivo. J Nutr Sci Vitaminol 52: 437-444.
12. El-Demerdash, F.M., Yousef, M.I., Kedwany, F.S. and Baghdadi, H.H. (2004) Cadmium induced changes in lipid peroxidation, blood hematology, biochemical parameters and semen quality of male rats: protective role of vitamin E and b-carotene. Food Chem Toxicol 42: 1563-1571.
13. Fahey, J.W. and Talalay, P. (2001) Phytochemicals from cruciferous plants protect against cancer by modulating carcinogen metabolism. J Nutr 131: 30275-30335.
14. Faure, P., Barclay, D., Joyeumx, F.M. and Halimi, S. (2007) Comparison of the effects of zinc alone and zinc associated with selenium and vitamin E on insulin sensitivity and oxidative stress in high fructose fed rats. J Trace Elem Med Biol 21: 113-119.
15. Gilabert, E.R., Ruiz, E., Osorio, C. and Ortega, E. (1996) Effect of dietary zinc deficiency on reproductive function in male rats: biochemical and morphometric parameters. J Nutr Biochem 7: 403-407.
16. Gunn, S.A. and Gould, T.C. (1970) Cadmium and other mineral elements. In: The Testis. Johnson, A.D., Gomes, W. R. and Van Demark, N.T., eds. Vol. II. New York: Academic Press, p. 377.
17. Gunn, S.A., Gould, T.C. and Anderson, W.A.D. (1963) Cadmiuminduced interstitial cell tumors in rats and mice and their prevention by zinc. J Nat Canc Inst 31: 745-759.
18. Henson, M.C. and Chedrese, P.J. (2004) Endocrine disruption by cadmium, a common environmental toxicant with paradoxical effects on reproduction. Biol Med 229: 383-392.
19. Johnson, A.D., Sigman, M.B. and Miller, W.J. (1970) Early actions of cadmium in the rat and domestic fowl testis: III. Subcellular location of injected cadmium. J Reprod Fertil 23: 201-213.
20. Kamel, M.M., Razek, A.H., Ahmed, K.A. and Kamel, G.M. (2011) Exposure of adult male rats to cadmium: Assessment of sexual behaviour, fertility, aggressive as well as anxiety like behavior with special reference to biochemical and pathological alterations. Life Sci 8: 106-119.
21. Kara, H., Cevik, A., Konar, V., Dayangac, A. and Yilmaz, M. (2007) Protective effects of antioxidants against cadmium-induced oxidative damage in rat testes. Biol Trace Elem 120: 205-211.
22. Khan, M.S.A., Hussain, S.A., Jais, A.M.M., Zakaria, Z.A. and Khan, M. (2011) Anti-ulcer activity of Ficus religiosa stem bark ethanolic extract in rats. J Med Plants Res 5: 354-359.
23. Kirana, H., Agrawal, S.S. and Srinivasan, B.P. (2009) Aqueous extract of Ficus religiosa Linn reduces oxidative stress in experimentally induced type 2 diabetic rats. Indian J Exp Biol 47: 822-826.
24. Koyuturk, M., Yanardag, R., Bolkent, S. and Sevim, T.S. (2006) Influence of combined antioxidant s against cadmium induced testicular damage. Environ Toxicol Pharmacol 21: 235-240.
25. Li, L. and Heindel, J. (1998) Sertoli cell Toxicants. Reprod Dev Toxicol 67:123- 129.
26. Li, Y., Zhang, T., Korkaya, H., Liu, S., Lee, H.F., Newman, B., et al. (2010) Sulforaphane, a dietary component of broccoli/broccoli sprouts, inhibits breast cancer stem cells. Clin Canc Res 16: 2580-2590.
27. Massoma, L., Gasco, M., Rubio, J., Yucra, S., Sock, E.N. and Gonzales, G.F. (2011) Effect of the ethanolic extract from Fagara tessmannii on testicular function, sex reproductive organs and hormonal level in adult male rats. J Androl 43: 139-144.
28. Niewenhuis, R.J. and Fende, P.L. (1978) The protective effect of selenium on cadmium-induced injury to normal and cryptorchid testes in the rat. Reprod Biol 19: 1-7.
29. Panda, H. (2005) Herb cultivation and medicinal uses (2nd ed). National Institute of Industrial Research; Delhi, India. pp. 302-303.
30. Parizek, J., Ostadalova, I., Kalouskova, J., Babicky, A. and Benes, J. (1971) The detoxifying effects of selenium. Interrelations between compounds of selenium and certain metals. In: Newer Trace Elements in Nutrition. Mertz, W. and Cornatzer, W. E, eds. New York: Marcel Dekker, pp. 85.
31. Predes, F.D., Diamante, M.A. and Dloder, H. (2010) Testis response to low doses of cadmium in wistar rats. Int J Exp Pathol 91: 125-131.
32. Riedl, M.A., Saxan A. and Sanchez. D. (2009) Oral sulforaphane increases Phase II antioxidant enzymes in the human upper airway. Clin Immunol 130: 244-251.
33. Said, L., Banni, M., Kerkeni, A., Said, K. and Messaoudi, I. (2010) Influence of combined treatment with zinc and selenium on cadmium induced testicular pathophysiology in rats. J Food Chem Toxicol 48: 2759-2765.
34. Stajn, A., Zikic, R.V., Ognjanovic, B., Saicic, Z.S., Pavlovi, V.M., Kostia, M., et al. (1997) Effect of cadmium and selenium on the antioxidant defense system in rat kidneys. Comp Biochem Physiol 117: 167-172.
35. Termellen, K. (2008) Oxidative stress and male infertility- a clinical prespective. Hum Reprod 14: 243-258.
36. Thomas, J.A. and Brogan, C.P. (1998) Some actions of lead on the sperm and on the male reproductive system. Am J Ind Med 4: 127-134.
37. Thompson, J. and Bannigan, J. (2008) Cadmium: toxic effects on the reproductive system and the embryo. Reprod Toxicol 25: 304-315.
38. Turner, T.T. and Lysiak, J.J. (2008) Oxidative stress: a common factor in testicular dysfunction. J Androl 299: 488-498.
39. Vernet, P., Aitken, R.J. and Drevet, J.R. (2004) Antioxidant strategies in the epididymis. Mol Cell Endocrinol 216: 31-39.
40. Waalkes, M.P. (2003) Cadmium carcinogenesis. Mutat 533: 107-120.
41. Waisberg, M., Joseph, P., Hale, B. and Beyersmann, D. (2003) Molecular and cellular mechanisms of cadmium carcinogenesis: a review. Toxicol 192: 95-117.
42. Webb, M. (1972) Protection by zinc against cadmium toxicity. Biochem. Pharmac 21: 2767-2771.
43. Yang, X.F., Wang, S.Y., Zhao, R.C., Ao, S.Q., Xu, L.C. and Wang, X.R. (2000) Changes in tissue metals after cadmium intoxication and intervention with chlorpromazine in male rats. Biomed Environ Sci 13: 19-25.
44. Yiin, S.J., Cheru, C.L., Sheu, J.Y. and Lin, T.H. (1999) Cadmium induced lipid peroxidation in rats' testes and protection by selenium. Biomet 12: 353-359.
45. Yucra, S., Sock, E.N. and Gonzales, G.F. (2008) Effect of different fractions from hydrolic extract of Black Maca (lepidium Meyenii) on testicular function in adult male rats. Fertil Steril 89: 1461-1467.