NSC126188 induces apoptosis of prostate cancer PC-3 cells through inhibition of Akt membrane translocation, FoxO3a activation, and RhoB transcription

Apoptosis

Volumn 19, Issue 1, 2014, Pages 179-190

  Won, Kyoung Jae ^a,b   Kim, Bo Kyung ^a   Han, Gyoonhee ^c   Lee, Kyeong ^d   Jung, Young Jin ^a,b   Kim, Hwan Mook ^a,e   Song, Kyung Bin ^f   Chung, Kyung Sook ^a   Won, Misun ^a,b  

^a Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

^b University of Science and Technology (UST)   (South Korea)

^c Yonsei University   (South Korea)

^d Dongguk University   (South Korea)

^e Gachon University College of Medicine   (South Korea)

^f Chungnam National University   (South Korea)

Author keywords

Akt; Apoptosis; Foxo3a; Nsci26188; Rhob

Indexed keywords

ANTINEOPLASTIC AGENT; INSULIN; NSC 126188; PIPERAZINE DERIVATIVE; PROTEIN KINASE B; RHOB GUANINE NUCLEOTIDE BINDING PROTEIN; TRANSCRIPTION FACTOR FKHRL1; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CANCER CELL; CELL DEATH; CELL MEMBRANE; DEPHOSPHORYLATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROSTATE CANCER CELL; UPREGULATION; WILD TYPE;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL LINE, TUMOR; CELL MEMBRANE; DOWN-REGULATION; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MALE; PIPERAZINES; PROSTATIC NEOPLASMS; PROTEIN TRANSPORT; PROTO-ONCOGENE PROTEINS C-AKT; RHOB GTP-BINDING PROTEIN; TRANSCRIPTION, GENETIC;

EID: 84892685304     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-013-0905-8     Document Type: Article

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