Cocaine-Induced changes of synaptic transmission in the striatum are modulated by adenosine A 2A receptors and involve the tyrosine phosphatase STEP

Neuropsychopharmacology

Volumn 39, Issue 3, 2014, Pages 569-578

  Chiodi, Valentina ^a   Mallozzi, Cinzia ^a   Ferrante, Antonella ^a   Chen, Jiang F ^b   Lombroso, Paul J ^c   Di Stasi, Anna Maria Michela ^a   Popoli, Patrizia ^a   Domenici, Maria Rosaria ^a  

^a ISTITUTO SUPERIORE DI SANITÀ   (Italy)

^b BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

A2A receptor; cocaine; STEP; striatum; synaptic transmission

Indexed keywords

4 [2 [7 AMINO 2 (2 FURYL) 1,2,4 TRIAZOLO[2,3 A][1,3,5]TRIAZIN 5 YLAMINO]ETHYL]PHENOL; ADENOSINE A2A RECEPTOR; BETA ACTIN; COCAINE; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2B; PROTEIN STEP; PROTEIN TYROSINE PHOSPHATASE; UNCLASSIFIED DRUG; VANADATE SODIUM;

ANIMAL TISSUE; ARTICLE; BRAIN REGION; BRAIN SLICE; BRAIN SYNAPTOSOME; CONTROLLED STUDY; CORPUS STRIATUM; EXCITATORY POSTSYNAPTIC POTENTIAL; GENE EXPRESSION; IN VIVO STUDY; KNOCKOUT MOUSE; LONG TERM DEPRESSION; MALE; MOUSE; NEUROMODULATION; NONHUMAN; PRIORITY JOURNAL; PSYCHOMOTOR DISORDER; SYNAPTIC TRANSMISSION; UPREGULATION; VOLTAGE CLAMP TECHNIQUE; WHOLE CELL;

ANIMALS; CEREBRAL CORTEX; COCAINE; CORPUS STRIATUM; DOPAMINE UPTAKE INHIBITORS; ENZYME INHIBITORS; GENE EXPRESSION REGULATION; HUMANS; INHIBITORY POSTSYNAPTIC POTENTIALS; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NEURAL PATHWAYS; NEURONS; PROTEIN TYROSINE PHOSPHATASES, NON-RECEPTOR; RECEPTOR, ADENOSINE A2A; SYNAPTIC TRANSMISSION; SYNAPTOSOMES; VANADATES;

EID: 84892681020     PISSN: 0893133X     EISSN: 1740634X     Source Type: Journal    
DOI: 10.1038/npp.2013.229     Document Type: Article

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