Severe dietary lysine restriction affects growth and body composition and hepatic gene expression for nitrogen metabolism in growing rats

Journal of Animal Physiology and Animal Nutrition

Volumn 98, Issue 1, 2014, Pages 149-157

  Kim, J ^a   Lee, K S ^a   Kwon, D H ^a   Bong, J J ^a   Jeong, J Y ^b   Nam, Y S ^a   Lee, M S ^a   Liu, X ^a,d   Baik, M ^c  

^a Chonnam National University   (South Korea)

^b National Institute of Animal Science   (South Korea)

^c Seoul National University   (South Korea)

^d YANBIAN UNIVERSITY   (China)

Author keywords

Arginase; Blood amino acids; Food intake; Intramuscular fat; mRNA

Indexed keywords

RATTUS;

AMINO ACID; ARGINASE; INTRAMUSCULAR FAT; LYSINE; MESSENGER RNA; NITROGEN;

ANIMAL; ARTICLE; BLOOD; BLOOD AMINO ACIDS; BODY COMPOSITION; DRUG EFFECT; ENZYMOLOGY; FOOD INTAKE; GENE EXPRESSION REGULATION; GENETICS; LIVER; MALE; METABOLISM; RAT; SPRAGUE DAWLEY RAT; UREA NITROGEN BLOOD LEVEL;

ARGINASE; BLOOD AMINO ACIDS; FOOD INTAKE; INTRAMUSCULAR FAT; MRNA;

AMINO ACIDS; ANIMALS; BLOOD UREA NITROGEN; BODY COMPOSITION; GENE EXPRESSION REGULATION; LIVER; LYSINE; MALE; NITROGEN; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER;

EID: 84892671355     PISSN: 09312439     EISSN: 14390396     Source Type: Journal    
DOI: 10.1111/jpn.12061     Document Type: Article

References (31)

1. Adibi, S. A., 1976: Metabolism of branched-chain amino acids in altered nutrition. Metabolism 25, 1287-1302.
2. Aparecida de Franca, S.; Dos Santos, M. P.; Garofalo, M. A.; Navegantes, L. C.; Kettelhut Ido, C.; Lopes, C. F.; Kawashita, N. H., 2009: Low protein diet changes the energetic balance and sympathetic activity in brown adipose tissue of growing rats. Nutrition 25, 1186-1192.
3. Apple, J. K.; Maxwell, C. V.; Brown, D. C.; Friesen, K. G.; Musser, R. E.; Johnson, Z. B.; Armstrong, T. A., 2004: Effects of dietary lysine and energy density on performance and carcass characteristics of finishing pigs fed ractopamine. Journal of Animal Science 82, 3277-3287.
4. Bieswal, F. M.; Ahn, T.; Reusens, B.; Holvoet, P.; Raes, M.; Rees, W.D.; Remacle, C., 2006: The importance of catch-up growth after early malnutrition for the programming of obesity in male rat. Obesity 14, 1330-1343.
5. Brookes, I. M.; Owens, F. N.; Garrigus, U. S., 1972: Influence of amino acid level in the diet upon amino acid oxidation by the rat. Journal of Nutrition 102, 27-36.
6. Chen, H. Y.; Lewis, A. J.; Miller, P. S.; Yen, J. T., 1999: The effect of excess protein on growth performance and metabolism of finishing barrows and gilts. Journal of Animal Science 77, 3238-3247.
7. Cherala, G.; Shapiro, B. H.; D'mello, A. P., 2006: Two low protein diets differentially affect food consumption and reproductive performance in pregnant and lactating rats and long-term growth in their offspring. Journal of Nutrition 136, 2827-2833.
8. Cieslak, D. G.; Benevenga, N. J., 1984: The effect of amino acid excess on utilization by the rat of the limiting amino acid-lysine. Journal of Nutrition 114, 1863-1870.
9. Dröge, W.; Holm, E., 1997: Role of cysteine and glutathione in HIV infection and other diseases associated with muscle wasting and immunological dysfunction. FASEB Journal 11, 1077-1089.
10. Du, F.; Higginbotham, D. A.; White, B. D., 2000: Food intake, energy balance and serum leptin concentrations in rats fed low-protein diets. Journal of Nutrition 130, 514-521.
11. Goto, S.; Nagao, K.; Bannai, M.; Takahashi, M.; Nakahara, K.; Kangawa, K.; Murakami, N., 2010: Anorexia in rats caused by a valine-deficient diet is not ameliorated by systemic ghrelin treatment. Neuroscience 166, 333-340.
12. Greenberg, D. M.; Ichihara, A., 1957: Further studies on the pathway of serine formation from carbohydrate. Journal of Biological Chemistry 224, 331-340.
13. Guo, F.; Cavener, D. R., 2007: The GCN2 eIF2alpha kinase regulates fatty-acid homeostasis in the liver during deprivation of an essential amino acid. Cell Metabolism 5, 103-114.
14. Kadowaki, M.; Kanazawa, T., 2003: Amino acids as regulators of proteolysis. Journal of Nutrition 133, 2052-2056.
15. Katsumata, M., 2011: Promotion of intramuscular fat accumulation in porcine muscle by nutritional regulation. Animal Science Journal 82, 17-25.
16. Katsumata, M.; Kobayashi, S. I.; Matsumoto, M.; Tsneishi, E.; Kaji, Y., 2005: Reduced intake of dietary lysine promotes accumulation of intramuscular fat in the longissimus dorsi muscles of finishing gilts. Animal Science Journal 76, 237-244.
17. Kerr, D. S.; Stevens, M. C.; Robinson, H. M., 1978: Fasting metabolism in infants. I. Effect of severe undernutrition on energy and protein utilization. Metabolism 27, 411-435.
18. Livak, K. J.; Schmittgen, T. D., 2001: Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 25, 402-408.
19. Nagao, K.; Bannai, M.; Seki, S.; Mori, M.; Takahashi, M., 2009: Adaptational modification of serine and threonine metabolism in the liver to essential amino acid deficiency in rats. Amino Acids 36, 555-562.
20. Nagao, K.; Bannai, M.; Seki, S.; Kawai, N.; Mori, M.; Takahashi, M., 2010: Voluntary wheel running is beneficial to the amino acid profile of lysine-deficient rats. American Journal of Physiology Endocrinology and Metabolism 298, 1170-1178.
21. Prior, R. L.; Milner, J. A.; Visek, W. J., 1975: Urea, citrate and orotate excretion in growing rats fed amino acid-deficient diets. Journal of Nutrition 105, 141-146.
22. Reeves, P. G.; Nielsen, F. H.; Fahey, G. C. Jr, 1993: AIN-93 purified diets for laboratory rodents: final report of the American Institute of Nutrition ad hoc writing committee on the reformulation of the AIN-76A rodent diet. Journal of Nutrition 123, 1939-1951.
23. Rodríguez-Sánchez, J. A.; Sanz, M. A.; Blanco, M.; Serrano, M. P.; Joy, M.; Latorre, M. A., 2011: The influence of dietary lysine restriction during the finishing period on growth performance and carcass, meat, and fat characteristics of barrows and gilts intended for dry-cured ham production. Journal of Animal Science 89, 3651-3662.
24. Ruusunen, M.; Partanen, K.; Pösö, R.; Puolanne, E., 2007: The effect of dietary protein supply on carcass composition, size of organs, muscle properties and meat quality of pigs. Livestock Science 107, 170-181.
25. Sawaya, A. L.; Lunn, P. G., 1998: Lowering of plasma triiodothyronine level and sympathetic activity does not alter hypoalbuminaemia in rats fed on a diet of low protein concentration. British Journal of Nutrition 79, 455-462.
26. Tanphaichitr, V.; Zaklama, M. S.; Broquist, H. P., 1976: Dietary lysine and carnitine: relation to growth and fatty livers in rats. Journal of Nutrition 106, 111-117.
27. Theys, N.; Bouckenooghe, T.; Ahn, M. T.; Remacle, C.; Reusens, B., 2009: Maternal low-protein diet alters pancreatic islet mitochondrial function in a sex-specific manner in the adult rat. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology 297, 1516-1525.
28. Vabulas, R. M.; Hartl, F. U., 2005: Protein synthesis upon acute nutrient restriction relies on proteasome function. Science 310, 1960-1963.
29. Witte, D. P.; Ellis, M.; McKeith, F. K.; Wilson, E. R., 2000: Effect of dietary lysine level and environmental temperature during the finishing phase on the intramuscular fat content of pork. Journal of Animal Science 78, 1272-1276.
30. Yang, Y. X.; Guo, J.; Jin, Z.; Yoon, S. Y.; Choi, J. Y.; Wang, M. H.; Piao, X. S.; Kim, B. W.; Chae, B. J., 2009: Lysine restriction and realimentation affected growth, blood profiles and expression of genes related to protein and fat metabolism in weaned pigs. Journal of Animal Physiology and Animal Nutrition 93, 732-743.
31. Young, V. R.; Pellett, P. L., 1944: Plant proteins in relation to human protein and amino acid nutrition. American Journal of Clinical Nutrition 59, 1203-1212.