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Volumn 10, Issue 1, 2014, Pages

T cell unresponsiveness in a pediatric cystic fibrosis patient: A case report

Author keywords

Cystic fibrosis; Na ve T cells; T cell differentiation; T cell exhaustion

Indexed keywords

CORTICOSTEROID; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; CYTOKINE; GAMMA INTERFERON; IMMUNOSUPPRESSIVE AGENT;

EID: 84892651753     PISSN: 17101484     EISSN: 17101492     Source Type: Journal    
DOI: 10.1186/1710-1492-10-2     Document Type: Article
Times cited : (7)

References (27)
  • 2
    • 0037460729 scopus 로고    scopus 로고
    • Cystic fibrosis
    • 10.1016/S0140-6736(03)12567-6, 12606185
    • Ratjen F, Doring G. Cystic fibrosis. Lancet 2003, 361:681-689. 10.1016/S0140-6736(03)12567-6, 12606185.
    • (2003) Lancet , vol.361 , pp. 681-689
    • Ratjen, F.1    Doring, G.2
  • 3
    • 0026520359 scopus 로고
    • Prediction of mortality in patients with cystic fibrosis
    • 10.1056/NEJM199204303261804, 1285737
    • Kerem E, Reisman J, Corey M, Canny GJ, Levison H. Prediction of mortality in patients with cystic fibrosis. N Engl J Med 1992, 326:1187-1191. 10.1056/NEJM199204303261804, 1285737.
    • (1992) N Engl J Med , vol.326 , pp. 1187-1191
    • Kerem, E.1    Reisman, J.2    Corey, M.3    Canny, G.J.4    Levison, H.5
  • 4
    • 0029286816 scopus 로고
    • Cystic fibrosis lung inflammation: early, sustained, and severe
    • Cantin A. Cystic fibrosis lung inflammation: early, sustained, and severe. Am J Respir Crit Care Med 1995, 151:939-941.
    • (1995) Am J Respir Crit Care Med , vol.151 , pp. 939-941
    • Cantin, A.1
  • 5
    • 0032906408 scopus 로고    scopus 로고
    • The innate immune system in cystic fibrosis lung disease
    • 10.1172/JCI6277, 407907, 9927489
    • Bals R, Weiner DJ, Wilson JM. The innate immune system in cystic fibrosis lung disease. J Clin Invest 1999, 103:303-307. 10.1172/JCI6277, 407907, 9927489.
    • (1999) J Clin Invest , vol.103 , pp. 303-307
    • Bals, R.1    Weiner, D.J.2    Wilson, J.M.3
  • 6
    • 84863359416 scopus 로고    scopus 로고
    • Distinct patterns of inflammation in the airway lumen and bronchial mucosa of children with cystic fibrosis
    • 10.1136/thoraxjnl-2011-200585, 22008188
    • Regamey N, Tsartsali L, Hilliard TN, Fuchs O, Tan HL, Zhu J, Qiu YS, Alton EW, Jeffery PK, Bush A, et al. Distinct patterns of inflammation in the airway lumen and bronchial mucosa of children with cystic fibrosis. Thorax 2012, 67:164-170. 10.1136/thoraxjnl-2011-200585, 22008188.
    • (2012) Thorax , vol.67 , pp. 164-170
    • Regamey, N.1    Tsartsali, L.2    Hilliard, T.N.3    Fuchs, O.4    Tan, H.L.5    Zhu, J.6    Qiu, Y.S.7    Alton, E.W.8    Jeffery, P.K.9    Bush, A.10
  • 7
    • 0034999076 scopus 로고    scopus 로고
    • Quantitative analysis of inflammatory cells infiltrating the cystic fibrosis airway mucosa
    • 10.1046/j.1365-2249.2001.01456.x, 1906034, 11359444
    • Hubeau C, Lorenzato M, Couetil JP, Hubert D, Dusser D, Puchelle E, Gaillard D. Quantitative analysis of inflammatory cells infiltrating the cystic fibrosis airway mucosa. Clin Exp Immunol 2001, 124:69-76. 10.1046/j.1365-2249.2001.01456.x, 1906034, 11359444.
    • (2001) Clin Exp Immunol , vol.124 , pp. 69-76
    • Hubeau, C.1    Lorenzato, M.2    Couetil, J.P.3    Hubert, D.4    Dusser, D.5    Puchelle, E.6    Gaillard, D.7
  • 8
    • 84875159113 scopus 로고    scopus 로고
    • A Th17- and Th2-skewed cytokine profile in cystic fibrosis lungs represents a potential risk factor for Pseudomonas aeruginosa infection
    • 10.1164/rccm.201206-1150OC, 23306544
    • Tiringer K, Treis A, Fucik P, Gona M, Gruber S, Renner S, Dehlink E, Nachbaur E, Horak F, Jaksch P, et al. A Th17- and Th2-skewed cytokine profile in cystic fibrosis lungs represents a potential risk factor for Pseudomonas aeruginosa infection. Am J Respir Crit Care Med 2013, 187:621-629. 10.1164/rccm.201206-1150OC, 23306544.
    • (2013) Am J Respir Crit Care Med , vol.187 , pp. 621-629
    • Tiringer, K.1    Treis, A.2    Fucik, P.3    Gona, M.4    Gruber, S.5    Renner, S.6    Dehlink, E.7    Nachbaur, E.8    Horak, F.9    Jaksch, P.10
  • 9
    • 21244455537 scopus 로고    scopus 로고
    • Role of IL-17A, IL-17 F, and the IL-17 receptor in regulating growth-related oncogene-alpha and granulocyte colony-stimulating factor in bronchial epithelium: implications for airway inflammation in cystic fibrosis
    • 2849297, 15972674
    • McAllister F, Henry A, Kreindler JL, Dubin PJ, Ulrich L, Steele C, Finder JD, Pilewski JM, Carreno BM, Goldman SJ, et al. Role of IL-17A, IL-17 F, and the IL-17 receptor in regulating growth-related oncogene-alpha and granulocyte colony-stimulating factor in bronchial epithelium: implications for airway inflammation in cystic fibrosis. J Immunol 2005, 175:404-412. 2849297, 15972674.
    • (2005) J Immunol , vol.175 , pp. 404-412
    • McAllister, F.1    Henry, A.2    Kreindler, J.L.3    Dubin, P.J.4    Ulrich, L.5    Steele, C.6    Finder, J.D.7    Pilewski, J.M.8    Carreno, B.M.9    Goldman, S.J.10
  • 11
    • 0027469563 scopus 로고
    • Detection of intracellular cytokines by flow cytometry
    • 10.1016/0022-1759(93)90158-4, 8445253
    • Jung T, Schauer U, Heusser C, Neumann C, Rieger C. Detection of intracellular cytokines by flow cytometry. J Immunol Methods 1993, 159:197-207. 10.1016/0022-1759(93)90158-4, 8445253.
    • (1993) J Immunol Methods , vol.159 , pp. 197-207
    • Jung, T.1    Schauer, U.2    Heusser, C.3    Neumann, C.4    Rieger, C.5
  • 13
    • 0348223787 scopus 로고    scopus 로고
    • Conversion of peripheral CD4 + CD25- naive T cells to CD4 + CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3
    • 10.1084/jem.20030152, 2194145, 14676299
    • Chen W, Jin W, Hardegen N, Lei KJ, Li L, Marinos N, McGrady G, Wahl SM. Conversion of peripheral CD4 + CD25- naive T cells to CD4 + CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3. J Exp Med 2003, 198:1875-1886. 10.1084/jem.20030152, 2194145, 14676299.
    • (2003) J Exp Med , vol.198 , pp. 1875-1886
    • Chen, W.1    Jin, W.2    Hardegen, N.3    Lei, K.J.4    Li, L.5    Marinos, N.6    McGrady, G.7    Wahl, S.M.8
  • 14
    • 33646168597 scopus 로고    scopus 로고
    • FOXP3: of mice and men
    • 10.1146/annurev.immunol.24.021605.090547, 16551248
    • Ziegler SF. FOXP3: of mice and men. Annu Rev Immunol 2006, 24:209-226. 10.1146/annurev.immunol.24.021605.090547, 16551248.
    • (2006) Annu Rev Immunol , vol.24 , pp. 209-226
    • Ziegler, S.F.1
  • 15
    • 66649114758 scopus 로고    scopus 로고
    • High antigen levels are the cause of T cell exhaustion during chronic viral infection
    • 10.1073/pnas.0809818106, 2688997, 19433785
    • Mueller SN, Ahmed R. High antigen levels are the cause of T cell exhaustion during chronic viral infection. Proc Natl Acad Sci USA 2009, 106:8623-8628. 10.1073/pnas.0809818106, 2688997, 19433785.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 8623-8628
    • Mueller, S.N.1    Ahmed, R.2
  • 18
    • 84868159278 scopus 로고    scopus 로고
    • Upregulation of the Tim-3/galectin-9 pathway of T cell exhaustion in chronic hepatitis B virus infection
    • 10.1371/journal.pone.0047648, 3480425, 23112829
    • Nebbia G, Peppa D, Schurich A, Khanna P, Singh HD, Cheng Y, Rosenberg W, Dusheiko G, Gilson R, Chin-Aleong J, et al. Upregulation of the Tim-3/galectin-9 pathway of T cell exhaustion in chronic hepatitis B virus infection. PLoS One 2012, 7:e47648. 10.1371/journal.pone.0047648, 3480425, 23112829.
    • (2012) PLoS One , vol.7
    • Nebbia, G.1    Peppa, D.2    Schurich, A.3    Khanna, P.4    Singh, H.D.5    Cheng, Y.6    Rosenberg, W.7    Dusheiko, G.8    Gilson, R.9    Chin-Aleong, J.10
  • 19
    • 84872737389 scopus 로고    scopus 로고
    • Chronic exposure to Plasmodium falciparum is associated with phenotypic evidence of B and T cell exhaustion
    • 10.4049/jimmunol.1202438, 3549224,3549224, 23264654
    • Illingworth J, Butler NS, Roetynck S, Mwacharo J, Pierce SK, Bejon P, Crompton PD, Marsh K, Ndungu FM. Chronic exposure to Plasmodium falciparum is associated with phenotypic evidence of B and T cell exhaustion. J Immunol 2013, 190:1038-1047. 10.4049/jimmunol.1202438, 3549224,3549224, 23264654.
    • (2013) J Immunol , vol.190 , pp. 1038-1047
    • Illingworth, J.1    Butler, N.S.2    Roetynck, S.3    Mwacharo, J.4    Pierce, S.K.5    Bejon, P.6    Crompton, P.D.7    Marsh, K.8    Ndungu, F.M.9
  • 20
    • 84865159642 scopus 로고    scopus 로고
    • T cell exhaustion in protozoan disease
    • 10.1016/j.pt.2012.07.001, 3768288, 22832368
    • Gigley JP, Bhadra R, Moretto MM, Khan IA. T cell exhaustion in protozoan disease. Trends Parasitol 2012, 28:377-384. 10.1016/j.pt.2012.07.001, 3768288, 22832368.
    • (2012) Trends Parasitol , vol.28 , pp. 377-384
    • Gigley, J.P.1    Bhadra, R.2    Moretto, M.M.3    Khan, I.A.4
  • 21
    • 79951684125 scopus 로고    scopus 로고
    • PD-1 and LAG-3 inhibitory co-receptors act synergistically to prevent autoimmunity in mice
    • 10.1084/jem.20100466, 3039848, 21300912
    • Okazaki T, Okazaki IM, Wang J, Sugiura D, Nakaki F, Yoshida T, Kato Y, Fagarasan S, Muramatsu M, Eto T, et al. PD-1 and LAG-3 inhibitory co-receptors act synergistically to prevent autoimmunity in mice. J Exp Med 2011, 208:395-407. 10.1084/jem.20100466, 3039848, 21300912.
    • (2011) J Exp Med , vol.208 , pp. 395-407
    • Okazaki, T.1    Okazaki, I.M.2    Wang, J.3    Sugiura, D.4    Nakaki, F.5    Yoshida, T.6    Kato, Y.7    Fagarasan, S.8    Muramatsu, M.9    Eto, T.10
  • 22
    • 77953395286 scopus 로고    scopus 로고
    • LAG-3 expression defines a subset of CD4(+)CD25(high)Foxp3(+) regulatory T cells that are expanded at tumor sites
    • 10.4049/jimmunol.0903879, 20421648
    • Camisaschi C, Casati C, Rini F, Perego M, De Filippo A, Triebel F, Parmiani G, Belli F, Rivoltini L, Castelli C. LAG-3 expression defines a subset of CD4(+)CD25(high)Foxp3(+) regulatory T cells that are expanded at tumor sites. J Immunol 2010, 184:6545-6551. 10.4049/jimmunol.0903879, 20421648.
    • (2010) J Immunol , vol.184 , pp. 6545-6551
    • Camisaschi, C.1    Casati, C.2    Rini, F.3    Perego, M.4    De Filippo, A.5    Triebel, F.6    Parmiani, G.7    Belli, F.8    Rivoltini, L.9    Castelli, C.10
  • 23
    • 0036773319 scopus 로고    scopus 로고
    • Inhibition of human T cell proliferation by CTLA-4 utilizes CD80 and requires CD25+ regulatory T cells
    • 10.1002/1521-4141(2002010)32:10<2888:AID-IMMU2888>3.0.CO;2-F, 12355442
    • Manzotti CN, Tipping H, Perry LC, Mead KI, Blair PJ, Zheng Y, Sansom DM. Inhibition of human T cell proliferation by CTLA-4 utilizes CD80 and requires CD25+ regulatory T cells. Eur J Immunol 2002, 32:2888-2896. 10.1002/1521-4141(2002010)32:10<2888:AID-IMMU2888>3.0.CO;2-F, 12355442.
    • (2002) Eur J Immunol , vol.32 , pp. 2888-2896
    • Manzotti, C.N.1    Tipping, H.2    Perry, L.C.3    Mead, K.I.4    Blair, P.J.5    Zheng, Y.6    Sansom, D.M.7
  • 24
    • 0029010464 scopus 로고
    • Activation of CFTR chloride current by nitric oxide in human T lymphocytes
    • 398388, 7540975
    • Dong YJ, Chao AC, Kouyama K, Hsu YP, Bocian RC, Moss RB, Gardner P. Activation of CFTR chloride current by nitric oxide in human T lymphocytes. EMBO J 1995, 14:2700-2707. 398388, 7540975.
    • (1995) EMBO J , vol.14 , pp. 2700-2707
    • Dong, Y.J.1    Chao, A.C.2    Kouyama, K.3    Hsu, Y.P.4    Bocian, R.C.5    Moss, R.B.6    Gardner, P.7
  • 25
    • 33847043963 scopus 로고    scopus 로고
    • IL-23 mediates inflammatory responses to mucoid Pseudomonas aeruginosa lung infection in mice
    • 2841977, 17071720
    • Dubin PJ, Kolls JK. IL-23 mediates inflammatory responses to mucoid Pseudomonas aeruginosa lung infection in mice. Am J Physiol Lung Cell Mol Physiol 2007, 292:L519-L528. 2841977, 17071720.
    • (2007) Am J Physiol Lung Cell Mol Physiol , vol.292
    • Dubin, P.J.1    Kolls, J.K.2
  • 26
    • 80051553123 scopus 로고    scopus 로고
    • The Th17 pathway in cystic fibrosis lung disease
    • 10.1164/rccm.201102-0236OC, 3381840, 21474644
    • Tan HL, Regamey N, Brown S, Bush A, Lloyd CM, Davies JC. The Th17 pathway in cystic fibrosis lung disease. Am J Respir Crit Care Med 2011, 184:252-258. 10.1164/rccm.201102-0236OC, 3381840, 21474644.
    • (2011) Am J Respir Crit Care Med , vol.184 , pp. 252-258
    • Tan, H.L.1    Regamey, N.2    Brown, S.3    Bush, A.4    Lloyd, C.M.5    Davies, J.C.6
  • 27
    • 84890258162 scopus 로고    scopus 로고
    • Intrinsic predisposition of naïve cystic fibrosis T cells to differentiate towards a Th17 phenotype
    • 10.1186/1465-9921-14-138, 3890528, 24344776
    • Kushwah R, Gagnon S, Sweezey NB. Intrinsic predisposition of naïve cystic fibrosis T cells to differentiate towards a Th17 phenotype. Respir Res 2013, 14:138. 10.1186/1465-9921-14-138, 3890528, 24344776.
    • (2013) Respir Res , vol.14 , pp. 138
    • Kushwah, R.1    Gagnon, S.2    Sweezey, N.B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.