Polymer-enhanced delivery increases adenoviral gene expression in an orthotopic model of bladder cancer

Journal of Controlled Release

Volumn 176, Issue 1, 2014, Pages 35-43

  Gosnell, Helen ^a   Kasman, Laura M ^a   Potta, Thrimoorthy ^b   Vu, Lucas ^b   Garrett Mayer, Elizabeth ^a   Rege, Kaushal ^b   Voelkel Johnson, Christina ^a  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^b Arizona State University   (United States)

Author keywords

Adenovirus; Bladder cancer; Cationic polymer; Gene delivery; Orthotopic

Indexed keywords

ADENOVIRUS; BLADDER CANCERS; CATIONIC POLYMERS; GENE DELIVERY; ORTHOTOPIC;

DISEASES; DRUG PRODUCTS; GENE EXPRESSION; GENE THERAPY; GENE TRANSFER;

FUNCTIONAL POLYMERS;

1,4 BIS (3 AMINOPROPYL)PIPERAZINE; AMIKACIN; AMINOGLYCOSIDE; NEOMYCIN; NEOPENTYLGLYCOL DIGLYCIDYL ETHER; ONCOLYTIC ADENOVIRUS; PAROMOMYCIN; POLYAMINE; POLYMER; UNCLASSIFIED DRUG;

ADENOVIRUS; ADENOVIRUS INFECTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLADDER CANCER; CANCER RESISTANCE; CELL MEMBRANE; CONTROLLED STUDY; GEL PERMEATION CHROMATOGRAPHY; GENE EXPRESSION; GENE THERAPY; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MOLECULAR WEIGHT; MOUSE; NONHUMAN; ONCOLYTIC VIROTHERAPY; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; REPORTER GENE; RESPIRATORY ARREST; RING OPENING; SYNTHESIS; VIRAL GENE DELIVERY SYSTEM; VIRUS CONCENTRATION; VIRUS INFECTIVITY;

ADENOVIRUS; BLADDER CANCER; CATIONIC POLYMER; GENE DELIVERY; ORTHOTOPIC;

ADENOVIRIDAE; AMINOGLYCOSIDES; ANIMALS; CELL LINE, TUMOR; GENE EXPRESSION; GENE TRANSFER TECHNIQUES; GREEN FLUORESCENT PROTEINS; HUMANS; LUCIFERASES; MICE; POLYMERS; URINARY BLADDER NEOPLASMS;

EID: 84892634747     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2013.12.012     Document Type: Article

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