Multiple sclerosis in the Mount Etna Region: Possible role of volcanogenic trace elements

PLoS ONE

Volumn 8, Issue 12, 2013, Pages

  Nicoletti, Alessandra ^a   Bruno, Elisa ^a   Nania, Martina ^a   Cicero, Edoardo ^a   Messina, Silvia ^a   Chisari, Clara ^a   Torrisi, Josita ^a   Maimone, Davide ^b   Marziolo, Roberto ^c   Fermo, Salvatore Lo ^a   Patti, Francesco ^a   Giammanco, Salvatore ^d   Zappia, Mario ^a  

^a UNIVERSITY OF CATANIA   (Italy)

^b GARIBALDI HOSPITAL   (Italy)

^c CANNIZZARO HOSPITAL   (Italy)

^d ISTITUTO NAZIONALE DI GEOFISICA E VULCANOLOGIA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

TRACE ELEMENT;

ADULT; ARTICLE; CONTROLLED STUDY; DISEASE DURATION; ENVIRONMENTAL EXPOSURE; FEMALE; HUMAN; INCIDENCE; ITALY; MAJOR CLINICAL STUDY; MALE; MULTIPLE SCLEROSIS; ONSET AGE; PREVALENCE; RISK FACTOR; SEX DIFFERENCE; VOLCANIC ASH; VOLCANO;

ADULT; AGE DISTRIBUTION; FEMALE; HUMANS; INCIDENCE; ITALY; MALE; MULTIPLE SCLEROSIS; PREVALENCE; SEX DISTRIBUTION; TRACE ELEMENTS; VOLCANIC ERUPTIONS;

EID: 84892612148     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0074259     Document Type: Article

References (43)

1. Poser CM (1994) The epidemiology of multiple sclerosis: a general overview. Ann Neurol 34: S180-193.
2. Alonso A, Hernan MA (2008) Temporal trends in the incidence of multiple sclerosis. A systematic review. Neurology 71: 129-135.
3. Pugliatti M, Rosati G, Cartonc H (2006) The epidemiology of multiple sclerosis in Europe. Eur J of Neurol 13: 700-722.
4. Ranzato F, Perini P, Tzintzeva E, Tiberio M, Calabrese M, et al. (2003) Increasing frequency of multiple sclerosis in Padova: a 30 year epidemiological survey. Mult Scler 9: 387-392.
5. Iuliano G, Napoletano R (2008) Prevalence and incidence of multiple sclerosis in Salerno (southern Italy) and its province. Eur J Neurol 15: 73-76.
6. Cocco E, Sardu C, Massa R, Mamusa E, Musu L, et al. (2011) Epidemiology of multiple sclerosis in south-western Sardinia. Mult Scler 17: 1282-1289.
7. Savettieri G, Ragonese P, Aridon P, Salemi G (2001) Epidemiology of multiple sclerosis in Sicily. Neurol Sci 22: 175-177.
8. Puthenparampil M, Seppi D, Rinaldi F, Federle L, Calabrese M, et al. (2013) Increased incidence of multiple sclerosis in the Veneto region, Italy. Multiple Sclerosis Epidemiology Veneto Study Group (MuSEV).Mult Scler 19(5):601-604.
9. Guidetti D, Cavalletti S, Merelli E, Zanoni P, Simonazzi P et al. (1995) Epidemiological survey of multiple sclerosis in the provinces of Reggio Emilia and Modena, Italy. Neuroepidemiology 14: 7-13.
10. Granieri E, Economou NT, De Gennaro R, Tola MR, Caniatti L, et al. (2007) Multiple sclerosis in the province of Ferrara: evidence for an increasing trend. J Neurol 254: 1642-1648.
11. Pugliatti M, Riise T, Sotgiu A, Sotgiu S, Satta WM, et al. (2005) Increasing incidence of multiple sclerosis in the province of Sassari, Northern Sardinia. Neuroepidemiology 25: 29-134.
12. Nicoletti A, Lo Bartolo ML, Lo Fermo S, Cocuzza V, Panetta MR, et al. (2001) Prevalence and incidence of multiple sclerosis in Catania, Sicily. Neurology 56: 62-66.
13. Nicoletti A, Patti F, Lo Fermo S, Sorbello V, Reggio E, et al. (2005) Possible increasing risk of multiple sclerosis in Catania, Sicily. Neurology 65: 1259-1263.
14. Nicoletti A, Patti F, Lo Fermo S, Messina S, Bruno E, et al. (2011) Increasing frequency of multiple sclerosis in Catania, Sicily: a 30-year survey. Mult Scler 17:273-280.
15. Handel AE, Giovannoni G, Ebers GC, Ramagopalan SV (2010) Environmental factors and their timing in adult-onsetmultiple sclerosis.Nat RevNeurol 6: 156-166.
16. Alimonti A, Ristori G, Giubilei F, Stazi MA, Pino A, et al. (2007) Serumchemical elements and oxidative status in Alzheimer's disease, Parkinson disease andmultiple sclerosis. Neurotoxicology 28: 450-456.
17. Ristori G, Brescianini S, Pino A, Visconti A, Vittori D, et al. (2011) Serumelements and oxidative status in clinically isolated syndromes: Imbalance andpredictivity Neurology 76: 549-555.
18. Hansell AL, Horwell CJ, Oppenheimer C (2006) The health hazards of volcanoes and geothermal areas. Occup Environ Med 63: 149-156.
19. Calabrese S, Aiuppa A, Allard P, Bagnato E, Bellomo S, et al. (2011) Atmospheric sources ad sinks of volcanogenic elements in a basaltic volcano (Etna, Italy). Geochi et Cosmoch Acta 75: 7401-7425.
20. Aiuppa A, Allard P, D'Alessandro W, Giammanco S, Parello F, et al. (2004) Magmatic gas leakage at Mount Etna (Sicily, Italy): Relationships with the volcano-tectonic structures, the hydrological pattern and the eruptive activity. Geophys Monogr Ser 143: 129-145.
21. Behncke B, Neri M (2003) Cycles and trends in the recent eruptive behaviour of Mount Etna (Italy). Can J Earth Sci 40: 1405-1411.
22. Branca S, Del Carlo P (2005) Types of eruptions of Etna volcano AD 16702003: implications for short-term eruptive behaviour. Bull Volcanol 67: 732-742.
23. Martin RS, Mather TA, Pyle DM, Watt SFL, Day JA, et al. (2009) Sweet chestnut (Castanea sativa) leaves as a bio-indicator of volcanic gas, aerosol and ash deposition onto the flanks of Mt Etna in 2005-2007. J Volcanol Geoth Res 179: 107-119.
24. Giammanco S, Ottaviani M, Valenza M, Veschetti E, Principio E, et al. (1998) Major and trace elements geochemistry in the ground waters of a volcanic area: Mount Etna (Sicily). Wat Res 32: 9-30.
25. Aiuppa A, Bellomo S, Brusca L, D'Alessandro W, Federico C, et al. (2003) Natural and anthropogenicfactors affecting groundwater quality of an active volcano (Mt. Etna, Italy). Applied Geochemistry 18: 863-882.
26. Istituto Centrale di Statistica (2011) 15° Censimento generale della popolazione.
27. Poser CM, Paty DW, Scheinberg L, McDonald WI, Davis FA, et al. (1983) New diagnostic criteria for multiple sclerosis: guidelines for research protocols. Ann Neurol 13: 227-231.
28. Giovannoni G, Ebers G (2007) Multiple sclerosis: the environment and causation. Curr Opin Neurol 20(3):261-268.
29. Riise T, Moen BE, Kyvik KR (2002) Organic solvents and the risk of multiple sclerosis. Epidemiology 6: 718-720.
30. Grønning M, Albrektsen G, Kvåle G, Moen B, Aarli JA, et al. (1993) Organic solvents and multiple sclerosis: a case-control study. Acta Neurol Scand 88: 247-250.
31. Schiffer RB, Mcdermott MP, Copley C (2001) A Multiple Sclerosis Cluster Associated with a Small, North-Central Illinois Community. Arch Environ Health 56: 389-395.
32. Purdey M (2004) Chronic barium intoxication disrupts sulphated proteoglycan synthesis: a hypothesis for the origins of multiple sclerosis. Med Hypotheses 62: 746-754.
33. Johnson S (2000) The possible role of gradual accumulation of copper, cadmium, lead and iron and gradual depletion of zinc, magnesium, selenium, vitamins B2, B6, D and E and essential fatty acids in multiple sclerosis. Med Hypotheses 55: 239-241.
34. Kapaki E, Segditsa J, Papageorgiou C (1989) Zinc, copper and magnesium concentration in serum and CSF of patients with neurological disorders. Acta Neurol Scand 79: 373-378.
35. Larsen C, White LR, Aasly J, Sjøbakk TE, Flaten TP, et al. (2003) Manganese, copper, and zinc in cerebrospinal fluid from patients with multiple sclerosis. Biol Trace Elem Res 93: 1-8.
36. Sayre LM, Perry G, Atwood CS, Smith MA (2000) The role of metals in neurodegenerative diseases. Cell Mol Biol (Noisy-le-grand) Jun;46(4):731-741.
37. Dhib-Jalbut S, Arnold DL, Cleveland DW, Fisher M, Friedlander RM, et al. (2006) Neurodegeneration and neuroprotection in multiple sclerosis and other neurodegenerative diseases. J Neuroimmunol Jul;176(1-2):198-215.
38. Gellein K, Skogholt JH, Aaseth J, Thoresen GB, Lierhagen S, et al. (2008)Trace elements in cerebrospinal fluid and blood from patients with a rare progressive central and peripheral demyelinating disease. J Neurol Sci; 266:70-78.
39. Klein R, Schwenk M, Templeton DM (2006) Cytokine Profiles In Human Exposure To Metals (Iupac Technical Report). Pure Appl Chem;78 (11):2155-2168.
40. Denkhaus E, Salnikow K (2002) Nickel essentiality, toxicity, and carcinogenicity. Crit Rev Oncol Hematol 42:35-56.
41. Gauthier PJ, Le Cloarec MF (1998) Variability of alkali and heavy metal fluxes released by Mt. Etna volcano, Sicily, between 1991 and 1995. J Volcanol Geotherm Res 81: 311-326.
42. Nicoletti A, Lo Fermo S, Reggio E, Tarantello R, Liberto A, et al. (2005) A possible spatial and temporal cluster of multiple sclerosis in the town of Linguaglossa, Sicily. J Neurol 252: 921-5.
43. Nicoletti A, Patti F, Lo Fermo S, Messina S, Bruno E, et al. (2009) A possible spatial and temporal cluster of multiple sclerosis in the town of Linguaglossa, Sicily: an update. Mult Scler 15:129-130.