Whole-exome sequencing to identify a novel LMNA gene mutation associated with inherited cardiac conduction disease

PLoS ONE

Volumn 8, Issue 12, 2013, Pages

  Lai, Chun Chi ^a   Yeh, Yung Hsin ^b   Hsieh, Wen Ping ^a   Kuo, Chi Tai ^b   Wang, Wen Ching ^a   Chu, Chia Han ^a   Hung, Chiu Lien ^a   Cheng, Chia Yang ^a   Tsai, Hsin Yi ^b   Lee, Jia Lin ^a   Tang, Chuan Yi ^a   Hsu, Lung An ^b  

^a NATIONAL TSING HUA UNIVERSITY   (Taiwan)

^b CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

LAMIN A;

ADULT; AGED; ARTICLE; ARTIFICIAL HEART PACEMAKER; ATRIOVENTRICULAR BLOCK; CHINESE; CLINICAL ARTICLE; CONTROLLED STUDY; FAMILY; FEMALE; GENE IDENTIFICATION; GENE MUTATION; GENE SEQUENCE; GENETIC SUSCEPTIBILITY; HEART ATRIUM FIBRILLATION; HEART MUSCLE CONDUCTION DISTURBANCE; HETEROZYGOSITY; HUMAN; LMNA GENE; MALE; MIDDLE AGED; MISSENSE MUTATION; NUCLEOTIDE SEQUENCE; PATHOGENICITY; PEDIGREE; SINUS NODE DISEASE; VERY ELDERLY; WHOLE EXOME SEQUENCING;

ADULT; AGED; AGED, 80 AND OVER; AMINO ACID SUBSTITUTION; ARRHYTHMIAS, CARDIAC; DNA MUTATIONAL ANALYSIS; EXOME; FAMILY; FEMALE; GENETIC DISEASES, INBORN; HEART CONDUCTION SYSTEM; HUMANS; LAMIN TYPE A; MALE; MIDDLE AGED; MUTATION, MISSENSE; PEDIGREE; PROTEIN STRUCTURE, TERTIARY;

EID: 84892609995     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0083322     Document Type: Article

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