Crystal structure of tropomyosin at 7 angstroms resolution

Proteins: Structure, Function and Genetics

Volumn 38, Issue 1, 2000, Pages 49-59

  Whitby, Frank G ^a,b   Phillips Jr , George N ^a  

^a RICE UNIVERSITY   (United States)

^b UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

Author keywords

Alpha helix; Coiled coil; Muscle regulation; Thin filament; Tropomyosin

Indexed keywords

ACTIN; CALCIUM; SPERMINE; TROPOMYOSIN; TROPONIN;

ALPHA HELIX; ANIMAL TISSUE; ARTICLE; GEOMETRY; HEART VENTRICLE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN STRUCTURE; SWINE; THIN FILAMENT;

ANIMALS; CRYOELECTRON MICROSCOPY; CRYSTALLOGRAPHY, X-RAY; MERCURY; MODELS, MOLECULAR; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; SPERMINE; TROPOMYOSIN;

ANIMALIA; SUS SCROFA;

EID: 0033985268     PISSN: 08873585     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0134(20000101)38:1<49::AID-PROT6>3.0.CO;2-B     Document Type: Article

References (51)

1. Harbury PB, Zhang T, Kim PS, Alber T. A switch between two-, three-, and four-stranded coiled coils in GCN4 leucine zipper mutants. Science 1993;262:1401-1406.
2. McLachlan AD, Stewart M. Tropomyosin coiled-coil interactions: evidence for an unstaggered structure. J Mol Biol 1975;98:293-304.
3. Parry DAD. Analysis of the primary sequence of α-tropomyosin from rabbit skeletal muscle. J Mol Biol 1975;98:519-535.
4. Stone D, Sodek J, Johnson P, Smillie LB. Tropomyosin: correlation of ammo acid sequence and structure. In Proteins of contractile systems, Vol. 31. Amsterdam: North Holland Publishing; 1976. p 125-136.
5. Cohen C, Holmes KC. X-ray diffraction evidence for alpha-helical coiled coils in native muscle. J Mol Biol 1963;6:423-432.
6. Crick FHC. The packing of alpha-helices: simple coiled-coils. Acta Cryst 1953;6:689-697.
7. McLachlan AD, Stewart M. The 14-fold periodicity in alpha-tropomyosin and the interaction with actin. J Mol Biol 1976;103: 271-298.
8. Phillips GN Jr, Fillers JP, Cohen C. Tropomyosin crystal structure and muscle regulation. J Mol Biol 1986;192:111-131.
9. Hitchcock-DeGregori SE. Structural requirements of tropomyosin for binding to filamentous actin. Adv Exp Med Biol 1994;358:85-96.
10. Hitchcock-DeGregori SE, Varnell TA. Tropomyosin has discrete actin-binding sites with sevenfold and fourteenfold periodicities. J Mol Biol 1990;214:885-896.
11. Kress M, Huxley HE, Faruqi AR, Hendrix J. Structural changes during activation of frog muscle studied by time-resolved X-ray diffraction. J Mol Biol 1986;188:325-342.
12. Bivin DB, Stone DB, Schneider DK, Mendelson RA. Cross-helix separation of tropomyosin molecules in acto-tropomyosin as determined by neutron scattering. Biophys J 1991;59:880-888.
13. Chacko S, Phillips GN Jr. Diffuse X-ray scattering from tropomyosin crystals. Biophys J 1992;61:1256-1266.
14. Phillips GN Jr., Chacko S. Mechanical properties of tropomyosin and implications for muscle regulation. Bolymers 1996;38:89-95.
15. Lehman W, Craig R, Vibert P. Calcium-induced tropomyosin movements in limulus thin filaments revealed by three-dimensional reconstruction. Nature 1994;368:65-67.
16. Lehman W, Vibert P, Ulman P, Craig R. Steric-Blocking by Tropomyosin Visualized in Relaxed Vertebrate Muscle Thin Filaments. J Mol Biol 1995;251:191-196.
17. Lorenz M, Poole KJ, Popp D, Rosenbaum G, Holmes KC. An atomic model of the unregulated thin filament obtained by X-ray fiber diffraction on oriented actin-tropomyosin gels. J Mol Biol 1995;246:108-119.
18. Zou G, Phillips GN Jr. A cellular automation model for the regulatory behavior of muscle thin filaments. Biophys J 1994;67: 11-28.
19. Crick FHC. Is alpha-keratin a coiled coil? Nature 1952;170:882-883.
20. Phillips GN Jr, Lattman EE, Cummins P, Lee KY, Cohen C. Crystal structure and molecular interactions of tropomyosin. Nature 1979;278:413-417.
21. Phillips GN Jr, Cohen C, Stewart M. A new crystal form of tropomyosin. J Mol Biol 1987;195:219-223.
22. Whitby FG, Kent H, Stewart F, et al. Structure of tropomyosin at 9 Angstroms resolution. J Mol Biol 1992;227:441-452.
23. Phillips GN Jr. What is the pitch of the alpha-helical coiled coil? Proteins 1992;14:425-429.
24. Hvidt S, Nestler HM, Greaser ML, Ferry JD. Flexibility of myosin rod determined from dilute solution viscoelastic measurements. Biochemistry 1982;21:4064-4073.
25. Stewart M, McLachlan AD, Calladine CR. A model to account for the elastic element in muscle crossbridges in terms of a bending myosin rod. Proc Roy Soc Lond 1987;B229:381-413.
26. Nilges M, Brunger AT. Automated modeling of coiled coils: application to the GCN4 dimerization region. Prot Engineer 1991;4:649-659.
27. Nilges M, Brunger AT. Successful prediction of the coiled coil geometry of the GCN4 leucine zipper domain by simulated annealing: comparison to the X-ray structure. Proteins 1993;15: 133-146.
28. O'Shea EK, Klemm JD, Kim PS, Alber T. X-ray structure of the GCN4 leucine zipper, a two-stranded parallel coiled coil. Science 1991;254:539-544.
29. Saudek V, Pastore A, Castiglione-Morelli MA, Frank R, Gausepohl H, Gibson T. The solution structure of a leucine-zipper motif peptide. Prot Engineer 1991;4:519-529.
30. Saudek V, Pastore A, Castiglione-Morelli MA, et al. solution structure of the DNA-binding domain of the yeast transcriptional activator protein GCN4. Prot Engineer 1990;4:3-10.
31. Casper DLD, Cohen C, Longley W. Tropomyosin: crystal structure, polymorphism and molecular interactions. J Mol Biol 1969;41:87-107.
32. Cohen C, Longley W. Tropomyosin paracrystals formed by divalent cations. Science 1966;152:794-796.
33. Stewart M. Tropomyosin: evidence for no stagger between chains. FEBS 1975b;53:5-7.
34. Stewart M. Structure of α-tropomyosin magnesium paracrystals. J Mol Biol 1981;148:411-425.
35. Stewart M, Diakiw V. Electron microscopic location of protein thiol residues. Nature 1978;274:184-186.
36. Stewart M, Lepault J. Cryoelectron microscopy of tropomyosin magnesium paracrystals. J Microscopy Pt. 1, 1985;138:53-60.
37. Stewart M, McLachlan AD. Fourteen actin binding sites on tropomyosin? Nature 1975;257:331-333.
38. Stewart M, McLachlan AD. Structure of magnesium paracrystals of tropomyosin. J Mol Biol 1976;103:251-269.
39. Avila-Sakar AJ, Schmid MF, Li L, Whitby FG, Phillips GN Jr, Chiu W. Preliminary electron crystallographic analysis of ice-embedded tropomyosin crystals. J Struct Biol 1993;110:67-74.
40. Xie X, Sudhakara R, Walian P, Hatch V, Phillips GN Jr, Cohen C. Coiled-coil packing in spermine-induced tropomyosin crystals: a comparative study of three forms. J Mol Biol 1994;236:1212-1226.
41. Hitchcock-DeGregori SE, Heald RW. Altered actin and troponin binding of amino-terminal variants of chicken striated muscle alpha-tropomyosin expressed in Escherichia coli. J Biol Chem 1987;262:9730-9735.
42. Lees-Miller JP, Helfman DM. The molecular basis for tropomyosin isoform diversity. BioEssays 1991;13:429-437.
43. Pittenger MF, Kazzaz JA, Helfman DM. Functional properties of non-muscle tropomyosin isoforms. Curr Opin Cell Biol 1994;6:96-104.
44. Eisenberg E, Kielley WW. Troponin-tropomyosin complex. J Biol Chem 1974;249:4742-4748.
45. Phillips GN Jr. Crystallization in capillary tubes. Methods Enzymol 1985;114:128-131.
46. Stewart M. The location of the troponin binding site on tropomyosin. Proc R Soc London Ser B, 1975a;190:257-266.
47. Kabsch W. Evaluation of single-crystal X-ray diffraction data from a position-sensitive detector. J Appl Cryst 1988;21:916-924.
48. Hendrickson WA, Smith JL, Phizackerly RP, Merritt EA. Crystallographic structure analysis of lamprey hemoglobin from anomalous dispersion of synchrotron radiation. Proteins 1988;4:77-88.
49. Brunger AT, Kuriyan J, Karplus M. Crystallographic R-factor refinement by molecular dynamics. Science 1987;235:458-460.
50. Furey W, Swaminathan S. PHASES: a program package for the processing and analysis of diffraction data from macromolecules. American Crystallographic Association meeting abstracts, 1990; 18:73.
51. McRee DE. A visual protein crystallographic software system for X11/XView. J Mol Graphics 1992;10:44-46.